Astrocyte Elevated Gene-1 Regulates {beta}-Catenin Signaling to Maintain Glioma Stem-like Stemness and Self-Renewal

This study discovers a previously unrecognized role of AEG-1 in GSC biology and supports the significance of this gene as a potential therapeutic target for glioblastoma multiforme. Mol Cancer Res; 15(2); 225–33. ©2016 AACR.

Source: Molecular Cancer Research - January 30, 2017 Category: Cancer & Oncology Authors: Hu, B., Emdad, L., Kegelman, T. P., Shen, X.-N., Das, S. K., Sarkar, D., Fisher, P. B. Tags: Signal Transduction Source Type: research