Cheap Drugs May Have Turned This Indian Lake Into A 'Superbug Hotspot'

Centuries ago, Indian princes would bathe in the cool Kazhipally lake in Medak. Now, even the poorest villagers here in India’s baking south point to the barren banks and frothy water and say they avoid going anywhere near it. A short drive from the bustling tech hub of Hyderabad, Medak is the heart of India’s antibiotics manufacturing business: a district of about 2.5 million that has become one of the world’s largest suppliers of cheap drugs to most markets, including the United States. But community activists, researchers and some drug company employees say the presence of more than 300 drug firms, combined with lax oversight and inadequate water treatment, has left lakes and rivers laced with antibiotics, making this a giant Petri dish for anti-microbial resistance. “Resistant bacteria are breeding here and will affect the whole world,” said Kishan Rao, a doctor and activist who has been working in Patancheru, a Medak industrial zone where many drug manufacturers have bases, for more than two decades. Drugmakers in Medak, including large Indian firms Dr Reddy’s Laboratories Ltd (REDY.NS), Aurobindo Pharma Ltd (ARBN.NS) and Hetero Drugs Ltd, and U.S. giant Mylan Inc (MYL.O), say they comply with local environmental rules and do not discharge effluent into waterways. National and local government are divided on the scale of the problem. While the Central Pollution Control Board (PCB) in New Delhi categorizes Medak’s Patancheru area ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

Related Links:

ConclusionsWe generated the first estimates of the incidence of CO-MRSA infections in Australia and identified stark regional differences in the nature and frequency of infections. Critically, we demonstrate that there has been a lack of consistency in reporting CO-MRSA and a general dearth of data. The only government in Australia that requires reporting of CO-MRSA is the Tasmanian, where the infection was least prevalent. Some regions of Australia have very high incidences of CO-MRSA. To improve surveillance and inform effective interventions, we recommend a standardized national reporting system in Australia that report...
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Abstract In Poland artisanal cheese production is an important local economic activity. Artisanal cheese is usually produced using raw cow's milk, animal rennet and salt, without the addition of starter cultures. Coagulase negative staphylococci (CoNS) are often present in artisanal cheeses. Pathogenic potential of some CoNS species, especially S. epidermidis, suggests that they could correspond to emerging pathogens. The identified risk factors correspond to virulence, antibiotic resistance and biofilm formation. Therefore, we aimed to characterize S. epidermidis isolated along the artisanal raw milk production c...
Source: International Journal of Food Microbiology - Category: Food Science Authors: Tags: Int J Food Microbiol Source Type: research
Conclusion: Overall, multiple factors, which are distinct for developing and developed countries, contribute to the increase in the prevalence of antibiotic resistance globally. The results highlight the need to improve the regulatory framework for antibiotic use and research globally.
Source: Journal of Global Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
(University of Plymouth) Amprologix Limited, a University of Plymouth spinout company, has won a £ 1.2 million contract from the Department for Health and Social Care to accelerate development and scale up its lead antibiotic candidate to tackle antimicrobial resistant MRSA and related superbugs.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
ConclusionsImplementation of AMR policy and decision-making should be guided only by reliable, unbiased estimates of effect size. Generating these estimates requires a thorough understanding of important biases and their impact on measured outcomes. This will ensure that researchers, clinicians, and other key decision makers concerned with increasing public health threat of AMR are accurately guided by the best available evidence.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Purpose: Parrots or psittacine birds are one of the most popular pets. The common problem in birds is respiratory disease, which spread mainly through contact, droplet and aerosol transmission. In particular, opportunistic bacteria normally involve in disease progression and threat of antimicrobial resistance. Moreover, close contact with a sick bird may pose health risk to owner due to spread of antibiotic-resistant bacteria. Thus, the aim of this work was to provide data on the characterization of antimicrobial resistance bacteria from upper respiratory tract of psittacine cases in Thailand.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 20.095 Source Type: research
öfle U, Torres C Abstract The aim of this study was to determine the carriage rate of coagulase-positive staphylococci (CoPS) in wild birds and to characterize recovered isolates. Tracheal samples from 324 wild birds, obtained in different Spanish regions during 2015-2016, were screened for CoPS carriage. The antimicrobial resistance profile and the virulence gene content were investigated. Molecular typing was performed by spa, agr, MLST, SCCmec, and S. delphini group classification. CoPS were recovered from 26 samples of wild birds (8.3%), and 27 isolates were further characterized. Two CoPS species were de...
Source: Microbial Ecology - Category: Microbiology Authors: Tags: Microb Ecol Source Type: research
The past two decades have witnessed an alarming expansion of staphylococcal disease caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). The factors underlying the epidemic expansion of CA-MRSA lineages such as USA300, the predominant CA-MRSA clone in the United States, are largely unknown. Previously described virulence and antimicrobial resistance genes that...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: PNAS Plus Source Type: research
ConclusionsThe first report to evaluated MSW against S. aureus and P. aeruginosa. However, environmental disinfection at low concentration sodium hypochlorite does not kill microorganisms. The proper use of sodium hypochlorite shows a bactericidal effect against various pathogenic microorganisms and is inexpensive, making it frequently used globally.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
This study reports the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in retail meat from Punjab, India.MethodsClassical microbiological methods were applied to isolate and identify S. aureus isolates. Isolates also underwent Etest. PCR and sequencing were used to identify and characterise antimicrobial resistance genes. MLST, SCCmec and spa typing were performed.ResultsA total of 408 meat and 101 swab samples were processed for S. aureus isolation. Phenotypic resistance was highest to penicillin (90.97%), followed by ciprofloxacin (61.80%), tetracycline (45.14%) and erythromycin (11.11%). Isolates from c...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
More News: Antimicrobial Resistance | Cardiology | Chemistry | Cipro | Ciprofloxacin | Drugs & Pharmacology | Environmental Health | Genetics | Government | Health | Heart | Infectious Diseases | Legislation | Pharmaceuticals | Study | Sulfamethoxazole | Superbugs | United Nations | Websites