A top 10 list waiting to save lives!

By Drs. David Niesel and Norbert Herzog Sometimes I have to remind myself we are in the 21st Century when I hear that infectious diseases are a leading cause of death among adults and remain the leading cause of death in children. While most of these deaths occur in the developing world, a significant number occur in middle income countries. Vaccines are the most cost effective medical intervention known to prevent infectious diseases. An effective vaccine can significantly reduce the mortality associated with them. However, while we have come a long way, the reality is that we have relatively few effective vaccines. One leading scientific magazine - "Science" recently asked infectious disease and vaccine experts for their opinions to prioritize vaccine development. This resulted in a ranking of ten infectious diseases in need of a vaccine and took into account the feasibility of producing one. So, in effect this is a top 10 list waiting to save lives. The top of the survey was Ebola Sudan, which is related to Ebola Zaire that was responsible for the West African outbreak involving more than 28,000 infected people and 11,000 deaths in 2014 and 2015. Remember that although there were only 4 cases in the US, the public was highly concerned about the possibility of Ebola infection spreading in the US. Next on the list is Chikungunya virus, which is spread by mosquitoes. This virus causes debilitating joint and muscle pain and is spreading across the Caribbean. As...
Source: Science - The Huffington Post - Category: Science Source Type: news

Related Links:

Authors: Noda A, Sakai T, Obara T, Miyazaki M, Tsuchiya M, Oyanagi G, Murai Y, Mano N Abstract BACKGROUND: There are no reports on investigations of the characteristics of adverse drug reaction (ADR) reports for pediatric patients in the Japanese Adverse Drug Event Report database (JADER) and the utility of database for drug safety surveillance in these patients. METHOD: We aimed to evaluate ADR reports for pediatric patients in the JADER. We used spontaneous ADR reports included in the JADER since April 1, 2004, to December 31, 2017, which was downloaded in April 2018. In a total of 504,407 ADR reports, the nu...
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research
Authors: Ambrosino I, Barbagelata E, Ortona E, Ruggieri A, Massiah G, Giannico OV, Politi C, Moretti AM Abstract In December 2019 a novel coronavirus emerged in Wuhan, China causing many cases of severe pneumonia. World Health Organization (WHO) named this disease Coronavirus Disease 2019 (COVID-19). The infection has rapidly spread across China to many other countries, and on March 12, 2020 the WHO declared pandemic outbreak of COVID-19. As of May 16, 2020, COVID-19 has been diagnosed in more than 4,490,000 patients, associated to 305,976 deaths worldwide; in Italy 224,760 COVID-19 cases have been reported with 31...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
Authors: Yadav SR, Kumar R, Gupta N, Ish P, Chakrabarti S, Kumar A Abstract To the Editor Novel Coronavirus disease (COVID-19) was first notified in December 2019 from Wuhan, China. Now, it has spread rapidly and has been declared a pandemic affecting over 200 countries with widespread morbidity and mortality. It has been postulated that the most vulnerable population are the elderly, people living in crowded areas, children and immune-compromised individuals, such as people living with human immunodeficiency virus (HIV). The correlation of tuberculosis (TB), HIV and malnutrition are well documented and hence, peop...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
The interplay of Hypertension, ACE-2 and SARS-CoV-2: Emerging data as the "Ariadne's thread" for the "labyrinth" of COVID-19. Hellenic J Cardiol. 2020 May 22;: Authors: Tsioufis C, Dimitriadis K, Tousoulis D PMID: 32450334 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Cardiology - Category: Cardiology Tags: Hellenic J Cardiol Source Type: research
CONCLUSIONS: The manifestations of COVID-19 at presentation were similar to those seen in other reports. Our population was older, slightly overrepresented by women and had a high level of co-morbidity. COVID-19 admittance was associated with frequent need of intensive care and mechanical ventilation that was associated with a very high mortality. FUNDING: none. TRIAL REGISTRATION: not relevant. PMID: 32448405 [PubMed - indexed for MEDLINE]
Source: Danish Medical Journal - Category: General Medicine Tags: Dan Med J Source Type: research
The American Institute of Biological Sciences (AIBS) joined 30 other scientific and medical associations to express deep concerns about the revocation of a National Institutes of Health (NIH) funded research grant to study coronavirus. Last month, NIH terminated a peer-reviewed research grant awarded in June 2019 that was investigating how coronaviruses move from their natural hosts to humans. The decision came after unverified reports from U.S. lawmakers and conservative media suggested that the SARS-CoV-2 virus responsible for the COVID-19 pandemic originated in a laboratory in Wuhan, China, which employs a Chinese vir...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
The U.S. House of Representatives passed a new coronavirus relief package, The Heroes Act, on May 15, 2020. If passed by the Senate and signed by the President, this will be the fifth measure adopted by Congress to respond to the COVID-19 pandemic. The $3 trillion stimulus bill includes $1 trillion in assistance for state, local, territorial, and tribal governments; $75 billion for coronavirus testing, contact tracing, and isolation measures; emergency supplemental appropriations to federal agencies; another round of direct payments; and $200 billion for a “Heroes’ fund” to provide hazard pay for essenti...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
The pandemic relief package, the Heroes Act, passed by the House on May 15, includes provisions of a scientific integrity bill that would protect federal scientists from political interference. The Scientific Integrity Act or SIA (H.R. 1709), sponsored by Representative Paul Tonko (D-NY), was approved by the House Science, Space, and Technology Committee in October 2019. Provisions of the legislation, which currently has 232 bipartisan cosponsors, were attached to the latest coronavirus relief measure as a manager’s amendment. SIA requires federal agencies that fund, conduct, or oversee scientific research to adop...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
Thirty-six scientific organizations, including AIBS, have expressed concerns about the April 22, 2020, Executive Proclamation Suspending Entry of Immigrants Who Present Risk to the U.S. Labor Market During the Economic Recovery Following the COVID-19 Outbreak. In a letter to President Trump, the groups wrote: “Our safety and return to daily activities following the COVID-19 outbreak will largely be delivered by America’s STEM enterprise. This enterprise will also play a vital role in U.S. economic recovery. Limiting immigration to the United States reduces our ability to attract the best available minds to thi...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
In the May 2020 issue of BioScience, AIBS President Dr. Charles Fenster and Executive Director Dr. Robert Gropp urge governments to coordinate to promote greater understanding of the SARS-CoV-2 pandemic, including the development of a vaccine. They further call on governments to “build the infrastructure needed to foster timely scientific exchange and the conversion of scientific information into responsible public policy - both domestically and internationally, for the current and future crises.” They further warn, “Understanding the origins of the current global health crisis resulting from the novel c...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
More News: African Health | Chikungunya | Child Development | Children | Coccidioidomycosis (Valley Fever) | Coronavirus | Ebola | Ebola Vaccine | Filovirus | Health | Infectious Diseases | Lassa Fever | Learning | Marburg Virus | MERS | Middle East Health | Outbreaks | Pain | Parasitic Diseases | Parasitology | Salmonella | SARS | Science | Texas University | Universities & Medical Training | Vaccines | Websites | Zika Virus