Knowledge of infection prevention and control among healthcare workers and factors influencing compliance: a systematic review
Conclusion: Embracing a multifaceted approach towards improving IPC-intervention strategies is highly suggested. The goal being to improve compliance among HCWs with IPC measures is necessary. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 16, 2021 Category: Consumer Health News Source Type: news

Anthony Fauci, 100 Days Into the Biden Administration, Is Finally Getting to Do His Job
When Dr. Anthony Fauci arrived at 1600 Pennsylvania Ave. for his first White House press briefing under the new Biden Administration, he could see things would be different. It was the day after the Inauguration, and President Joe Biden was eager to get the country’s COVID-19 response back on track. Five minutes before he addressed the public, Fauci spoke with the new President. “He said, ‘I want you to just go and tell the science, explain to people that if we make mistakes, we’re going to fix the mistakes and we’re not going to dwell on the mistakes. Let science be communicated to the public...
Source: TIME: Health - May 18, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

MERS DNA vaccine induces immunity, protects from virus challenge in preclinical model
(The Wistar Institute) A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at Wistar induced potent immune responses and afforded protective efficacy in non-human primate models when given intradermally in abbreviated, low-dose immunization regimen. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 22, 2021 Category: Biology Source Type: news

Exclusive: Inside the Facilities Making the World ’s Most Prevalent COVID-19 Vaccine
If you’ve been vaccinated for COVID-19, chances are pretty high that you’re benefiting from a product made by BioNTech. The German biotech company, co-founded by a husband-and-wife team of scientists, developed the vaccine that became not only the first to earn authorization in the U.S. for COVID-19 in December but also the first ever based on a new technology involving the genetic material mRNA. In interviews in December and March, co-founders Ugur Sahin and Ozlem Tureci spoke about their whirlwind year and their partnership with U.S. pharmaceutical company Pfizer to test and manufacture the vaccine. Over thre...
Source: TIME: Health - April 19, 2021 Category: Consumer Health News Authors: Alice Park and Aryn Baker/Marburg, Germany Tags: Uncategorized COVID-19 Exclusive feature longform Magazine photography Source Type: news

Microbicidal actives with virucidal efficacy against SARS-CoV-2 and other beta- and alpha-coronaviruses and implications for future emerging coronaviruses and other enveloped viruses, Scientific reports
Mitigating the risk of acquiring coronaviruses including SARS-CoV-2 requires awareness of the survival of virus on high-touch environmental surfaces (HITES) and skin, and frequent use of targeted microbicides with demonstrated efficacy. The data on stability of infectious SARS-CoV-2 on surfaces and in suspension have been put into perspective, as these inform the need for hygiene. We evaluated the efficacies of formulated microbicidal actives against alpha- and beta-coronaviruses, including SARS-CoV-2. The coronaviruses SARS-CoV, SARS-CoV-2, human coronavirus 229E, murine hepatitis virus-1, or MERS-CoV were deposited on pr...
Source: Current Awareness Service for Health (CASH) - April 15, 2021 Category: Consumer Health News Source Type: news

Researchers Are Hatching a Low-Cost Covid-19 Vaccine
A new formulation entering clinical trials in Brazil, Mexico, Thailand and Vietnam could change how the world fights the pandemic. (Source: NYT Health)
Source: NYT Health - April 5, 2021 Category: Consumer Health News Authors: Carl Zimmer Tags: your-feed-science Clinical Trials Coronavirus (2019-nCoV) MERS (Middle East Respiratory Syndrome) Eggs Immune System Influenza Factories and Manufacturing Antibodies Drugs (Pharmaceuticals) Biology and Biochemistry Gates, Bill and Me Source Type: news

The covid bio-terrorism trail leads back to CCP collaborators, Anthony Fauci and Peter Daszak
(Natural News) When controversial, gain-of-function virus research was banned in the United States in October of 2014, top scientists in the government and in the private sector had to immediately halt twenty-one projects related to virus manipulation and vaccine development for influenza viruses and coronaviruses like SARS and MERS. Controversial projects at Harvard, Emory and... (Source: NaturalNews.com)
Source: NaturalNews.com - March 31, 2021 Category: Consumer Health News Source Type: news

Potential COVID-19 treatment identified in UCLA-led lab study
This study identified a new potential therapy that could help the global fight against COVID-19 and support populations that have been disproportionately affected by this deadly disease.”Drugs are categorized as small molecules when their individual molecules are tiny enough that they can penetrate to where they are needed. The researchers screened 430 drugs from among the approximately 200,000 compounds in CNSI ’sMolecular Screening Shared Resource libraries. They identified 34  that demonstrated at least some ability to halt the coronavirus, and eight that did so at relatively lower doses, before zeroing...
Source: UCLA Newsroom: Health Sciences - March 24, 2021 Category: Universities & Medical Training Source Type: news

ICYMI: WSJ showcases breakthrough science of COVID-19 vaccines and implications for future medicines
Building on deep scientific knowledge gained from decades of experience with viruses such as MERS, SARS, influenza, HIV and Hepatitis C, biopharmaceutical companies have madeunprecedented progress in advancing treatments and vaccines to help fight COVID-19. At this time, three vaccines and several treatments have received emergency use authorizations (EUAs) from the U.S. Food and Drug Administration (FDA) with one treatment receiving FDA approval. Additional candidates under investigation have also shown promise. (Source: The Catalyst)
Source: The Catalyst - March 8, 2021 Category: Pharmaceuticals Tags: Vaccines Coronavirus Source Type: news

FDA abandons informed consent after “emergency use” approval of JJ coronavirus vaccine, which SKIPPED large-scale safety testing
(Natural News) Johnson and Johnson’s single dose coronavirus vaccine was recently granted “emergency use” approval by the Food and Drug Administration (FDA). This means J&J skipped large scale safety testing for their experimental biologic. To make matters worse, all previous attempts to create a safe and effective coronavirus vaccine (SARS and MERS) have failed and... (Source: NaturalNews.com)
Source: NaturalNews.com - March 4, 2021 Category: Consumer Health News Source Type: news

Association between chronic fatigue syndrome and suicidality among survivors of Middle East respiratory syndrome over a 2-year follow-up period - Ahn SH, Kim JL, Kim JR, Lee SH, Yim HW, Jeong H, Chae JH, Park HY, Lee JJ, Lee H.
Suicide is an important public health issue during the current pandemic of emerging infectious diseases (EIDs). In EIDs, various symptoms persist even after recovery, and chronic fatigue is among those that are commonly reported. The aim of this study was ... (Source: SafetyLit)
Source: SafetyLit - March 4, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

< a href= " /news-events/nih-research-matters/antibody-treatment-mers-coronavirus-safe-people " > Antibody treatment for MERS coronavirus safe in people < /a >
A combination of two monoclonal antibodies prevented and effectively treated Middle East Respiratory Syndrome (MERS) in mice. (Source: NIH Research Matters)
Source: NIH Research Matters - March 2, 2021 Category: Research Source Type: news

Monoclonal antibodies against MERS coronavirus show promise in Phase 1 NIH-sponsored trial
Antibodies were well tolerated and generally safe when administered simultaneously to healthy adults. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - February 23, 2021 Category: American Health Source Type: news

Monoclonal antibodies against MERS coronavirus show promise in phase 1 NIH-sponsored trial
(NIH/National Institute of Allergy and Infectious Diseases) A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal antibodies (mAbs) directed against the coronavirus that causes MERS found that they were well tolerated and generally safe when administered simultaneously to healthy adults. The experimental mAbs target the MERS coronavirus (MERS CoV) spike protein used by the virus to attach to and infect target cells. The mAbs were discovered and developed by scientists at the biopharmaceutical company Regeneron. The trial was sponsored by NIAID. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 23, 2021 Category: Infectious Diseases Source Type: news

Vaccinate, don ’t hesitate!
UNISON doesn’t think that people should be forced to be vaccinated, but the union is encouraging members to get the vaccine when they have the chance. Vice president James Anthony – a frontline NHS worker – has had his first dose, so we fired a few questions in his direction. James, you’re a frontline worker in a hospital and you’ve been caring for COVID patients during the pandemic – what’s that been like? I’m a nurse specialist and, in the first peak, I was mostly doing a lot of advice work with our patients, many of whom were very scared, while also looking after my heart ...
Source: UNISON Health care news - February 12, 2021 Category: UK Health Authors: Amanda Kendal Tags: Article News Covid-19 vaccine Source Type: news

A series of knocks: Oxford/AstraZeneca's bumpy road to Covid vaccine confidence
From doubts about safety in older people to questions about variants, scientists have faced a battle to convince the public and regulatorsCoronavirus – latest updatesSee all our coronavirus coverageThe Oxford University/AstraZeneca vaccine against Covid has barely been out of the news from the moment the race to protect the world ’s population from the novel coronavirus began. But not always in a good way.Talented scientists at the Jenner Institute at Oxford University, led by Prof Sarah Gilbert, were incredibly quick off the mark in developing a potential vaccine, as soon as the virus in Wuhan had been sequenc...
Source: Guardian Unlimited Science - February 9, 2021 Category: Science Authors: Sarah Boseley Health editor Tags: Coronavirus Vaccines and immunisation Health Infectious diseases Medical research Science Society World news University of Oxford Higher education Pharmaceuticals industry Regulators Business Source Type: news

Middle East respiratory syndrome coronavirus (MERS-CoV) – The Kingdom of Saudi Arabia
Between 1 June through 31 December 2020, the National IHR Focal Point of Saudi Arabia reported four additional cases of Middle East respiratory syndrome (MERS-CoV) with one associated death. The cases were reported from Riyadh (two cases), Taif (one case), and Al-Ahsaa (one case) Regions. The link below provides details of the four reported cases. (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - February 1, 2021 Category: Infectious Diseases Tags: news Source Type: news

mRNA Technology Gave Us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry
“No!” The doctor snapped. “Look at me!” I had been staring her in the eyes, as she had ordered, but when a doctor on my other side began jabbing me with a needle, I started to turn my head. “Don’t look at it,” the first doctor said. I obeyed. This was in early August in New Orleans, where I had signed up to be a participant in the clinical trial for the Pfizer-BioNTech COVID-19 vaccine. It was a blind study, which meant I was not supposed to know whether I had gotten the placebo or the real vaccine. I asked the doctor if I would really been able to tell by looking at the syringe. &...
Source: TIME: Health - January 11, 2021 Category: Consumer Health News Authors: Walter Isaacson Tags: Uncategorized COVID-19 feature Magazine Source Type: news

mRNA Technology Gave Us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry
“No!” The doctor snapped. “Look at me!” I had been staring her in the eyes, as she had ordered, but when a doctor on my other side began jabbing me with a needle, I started to turn my head. “Don’t look at it,” the first doctor said. I obeyed. This was in early August in New Orleans, where I had signed up to be a participant in the clinical trial for the Pfizer-BioNTech COVID-19 vaccine. It was a blind study, which meant I was not supposed to know whether I had gotten the placebo or the real vaccine. I asked the doctor if I would really been able to tell by looking at the syringe. &...
Source: TIME: Science - January 11, 2021 Category: Science Authors: Walter Isaacson Tags: Uncategorized COVID-19 feature Magazine Source Type: news

Recovery from COVID-19, RCGP (updated 4th January 2021)
This 30-minute, updated (4th January 2021) RCGP Learning course summarises what is known so far about sequelae of COVID-19 and reflects on what can be learnt from other causes of severe illness, including previous coronavirus outbreaks, for example Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 4, 2021 Category: Consumer Health News Source Type: news

Origin story: what do we know now about where coronavirus came from?
When Chinese scientists alerted colleagues to a new virus last December, suspicion fell on a Wuhan market. What have health officials learned since then?Show your support for rigorous, independent Guardian journalismCoronavirus – latest updatesSee all our coronavirus coverageMaria van Kerkhove was staying with her sister in the US for the Christmas holidays, but checking her emails. As always. Every day there are signals of potential trouble, said the World Health Organization virologist who was to become a household name and face within weeks.“There’s always something that happens at Christmas time. Ther...
Source: Guardian Unlimited Science - December 12, 2020 Category: Science Authors: Sarah Boseley Tags: Coronavirus Medical research Infectious diseases Biology World news Health China Asia Pacific World Health Organization Microbiology Science Society Long Covid Animals Source Type: news

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a grave threat to public health and the global economy. SARS-CoV-2 is closely related to the more lethal but less transmissible coronaviruses SARS-CoV-1 and Middle East respiratory syndrome coronavirus (MERS-CoV). Here, we have carried out comparative viral-human protein-protein interaction and viral protein localization analyses for all three viruses. Subsequent functional genetic screening identified host factors that functionally impinge on coronavirus proliferation, including Tom70, a mitochondrial chaperone protein that i...
Source: ScienceNOW - December 3, 2020 Category: Science Authors: Gordon, D. E., Hiatt, J., Bouhaddou, M., Rezelj, V. V., Ulferts, S., Braberg, H., Jureka, A. S., Obernier, K., Guo, J. Z., Batra, J., Kaake, R. M., Weckstein, A. R., Owens, T. W., Gupta, M., Pourmal, S., Titus, E. W., Cakir, M., Soucheray, M., McGregor, M Tags: Engineering, Microbiology, Online Only r-articles Source Type: news

The long game: the race for a vaccine against all coronaviruses
There is hope that Covid-19 immunisation might soon be a reality, but some scientists are aiming for a broader solutionCoronavirus – latest updatesSee all our coronavirus coverageHopes have been raised worldwide this week that a Covid-19 vaccine is getting closer, after one version was shown to be 90% effective in reducing disease symptoms, but a handful of scientists are working on an ambitious plan for a different sort of vaccine.Their project, which is fraught with technical and financial challenges, is to find a vaccine that could protect against not just Covid, but other viruses in the same family that cause Sar...
Source: Guardian Unlimited Science - November 13, 2020 Category: Science Authors: Natalie Grover Tags: Coronavirus Infectious diseases Medical research Microbiology Science World news Vaccines and immunisation Health Society Source Type: news

The Covid-carrying Danish mink are a warning sign – but is anyone heeding it? | Matthew Baylis
Sars, Mers, now this: we must think hard about how we farm animals that are known hosts of human coronavirusesTwo decades ago, aseminal study from the University of Edinburgh compiled a list of all known human infectious diseases. It found a total of 1,415 different human pathogens, and claimed that 61% were capable of spreading between humans and animals. Today, with the world put on hold by adeadly disease that seems likely to have spread first from bats to humans, we know the dangerous effects of such pathogens all too well.The group of diseases that spread from animals to humans are collectively known as zoonoses. The ...
Source: Guardian Unlimited Science - November 10, 2020 Category: Science Authors: Matthew Baylis Tags: Coronavirus Farming Environment Science Sars Infectious diseases Denmark Europe Source Type: news

The Covid Pandemic: Broadening the Discourse
Thailand’s COVID-19 response an example of resilience and solidarity: a UN Resident Coordinator’s BlogBy Asoka BandarageCOLOMBO, Sri Lanka, Nov 10 2020 (IPS) SARS-CoV-2, the corona virus that causes COVID-19, has been spreading exponentially across the world over the last ten or so months. As of November 6th, according to the Center for Systems Science at Johns Hopkins University, there have been 49,195,581 cases of COVID-19, including 1,241,031 deaths. More than a third of the global population has been placed on lockdown. The global economy is experiencing the deepest global recession since World War 2 and m...
Source: IPS Inter Press Service - Health - November 10, 2020 Category: International Medicine & Public Health Authors: Asoka Bandarage Tags: Featured Global Headlines Health Human Rights Humanitarian Emergencies Peace TerraViva United Nations Source Type: news

Supporting resilience and mental well-being in frontline healthcare professionals during and after a pandemic
This study was carried out immediately after the Ebola outbreak, and investigated whether staff who were training to give other people (such as patients and their family members)'psychological first aid'felt less ‘burnt out’. The authors had some concerns about the results that this study reported and about some of its methods. This means that confidence in the evidence is very low and the authors cannot say whether the intervention helped or not.Objective 2: all 16 studies provided some evidence about barriers and facilitators to implement interventions. The author team found 17 main findings from these studie...
Source: Cochrane News and Events - November 5, 2020 Category: Information Technology Authors: Katie Abbotts Source Type: news

Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a global crisis. Key to SARS-CoV-2 therapeutic development is unraveling the mechanisms that drive high infectivity, broad tissue tropism, and severe pathology. Our 2.85-angstrom cryo–electron microscopy structure of SARS-CoV-2 spike (S) glycoprotein reveals that the receptor binding domains tightly bind the essential free fatty acid linoleic acid (LA) in three composite binding pockets. A similar pocket also appears to be present in the highly pathogenic severe acute respiratory syndrome coronaviru...
Source: ScienceNOW - November 5, 2020 Category: Science Authors: Toelzer, C., Gupta, K., Yadav, S. K. N., Borucu, U., Davidson, A. D., Kavanagh Williamson, M., Shoemark, D. K., Garzoni, F., Staufer, O., Milligan, R., Capin, J., Mulholland, A. J., Spatz, J., Fitzgerald, D., Berger, I., Schaffitzel, C. Tags: Biochemistry reports Source Type: news

New COVID-19 related genes — helpful and harmful — found in massive screen
Research by Yale and partner institutions sheds new light on the genetics behind cells ’ susceptibility to infection by SARS-Cov-2 and MERS viruses. (Source: Yale Science and Health News)
Source: Yale Science and Health News - October 26, 2020 Category: Universities & Medical Training Source Type: news

New COVID-19 related genes -- helpful and harmful -- found in massive screen
(Yale University) Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus. The pro-viral and anti-viral role of these genes will help guide scientists in development of new therapies to combat COVID-19, the researchers say. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 26, 2020 Category: International Medicine & Public Health Source Type: news

COMMENTARY: The Sinatra Doctrine Confronts a Global Consensus
A photo-collage. Credit: Peter Costantini.By Peter CostantiniSEATTLE, Oct 23 2020 (IPS) By late September, the COVID-19 pandemic in the United States had claimed 200,000 lives. That’s equivalent to a slightly higher toll than the 418,500 United States deaths in World War II, adjusted for relative population and duration. [See note below.] With four percent of the world’s population, the U.S. has suffered 20 percent of global COVID-19 deaths. Tragically, most of these deaths need never have happened. They were caused primarily by the public-health equivalent of friendly fire: massive malpractice and deception by...
Source: IPS Inter Press Service - Health - October 23, 2020 Category: International Medicine & Public Health Authors: Peter Costantini Tags: Global Geopolitics Global Governance Headlines Health TerraViva United Nations Source Type: news

What Developing Countries Can Teach Us About How To Respond To a Pandemic
This article is republished from The Conversation under a Creative Commons license. Read the original article. The post What Developing Countries Can Teach Us About How To Respond To a Pandemic appeared first on Inter Press Service. (Source: IPS Inter Press Service - Health)
Source: IPS Inter Press Service - Health - October 16, 2020 Category: International Medicine & Public Health Authors: External Source Tags: Global Headlines Health TerraViva United Nations Source Type: news

Scientists identify common vulnerabilities across SARS-CoV-2, SARS-CoV-1 and MERS coronaviruses
In a study published online in Science, an international team of almost 200 researchers from 14 leading institutions in six countries, including France with the Institut Pasteur and CNRS, studied the three lethal coronaviruses SARS-CoV-2, SARS-CoV-1 and MERS-CoV in order to identify commonly hijacked cellular pathways and detect promising targets for broad coronavirus inhibition. In addition, (Source: World Pharma News)
Source: World Pharma News - October 16, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

The mental health impact of pandemics for front line health care staff
(University of East Anglia) New research shows the impact that pandemics have on the mental health of front-line health care staff.Researchers investigated how treating patients in past pandemics such as SARS and MERS affected the mental health of front-line staff.They found that over a third experienced anxiety or depression, almost a quarter experienced PTSD.The team hope that their work will help highlight the impact that the Covid-19 pandemic could be having on the mental health of doctors and nurses worldwide. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 16, 2020 Category: Infectious Diseases Source Type: news

Aetion statement on UCSF-led study to inform drug development for COVID-19, future pandemics
(Aetion) Aetion co-authored a study published today inScience, which examined lethal coronaviruses SARS-CoV-2, SARS-CoV-1, and MERS-CoV to identify molecular characteristics of potential treatments. The study, which was led by the Quantitative Biosciences Institute at UCSF and involved nearly 200 researchers from leading institutions, applied a novel approach to evaluate molecular hypotheses by analyzing real-world data from COVID-19 patients. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 15, 2020 Category: Infectious Diseases Source Type: news

Global study identifies common vulnerabilities across SARS-CoV-2, SARS-CoV-1 and MERS coronaviruses
(Georgia State University) There are common vulnerabilities among three lethal coronaviruses, SARS-CoV-2, SARS-CoV-1 and MERS-CoV, such as frequently hijacked cellular pathways, that could lead to promising targets for broad coronavirus inhibition, according to a study by an international research team that includes scientists from the Institute for Biomedical Sciences at Georgia State University. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 15, 2020 Category: Infectious Diseases Source Type: news

Team of international scientists identify common vulnerabilities across coronaviruses
(University of California - San Francisco) In a study published online inScience, today, an international team of almost 200 researchers from 14 leading institutions in six countries studied the three lethal coronaviruses SARS-CoV-2, SARS-CoV-1 and MERS-CoV in order to identify commonly hijacked cellular pathways and detect promising targets for broad coronavirus inhibition. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 15, 2020 Category: Infectious Diseases Source Type: news

Repurposing drugs for a pan-coronavirus treatment
(European Molecular Biology Laboratory - European Bioinformatics Institute) The study identifies drug targets common to all three coronaviruses (SARS-CoV-2, SARS-CoV-1, and MERS-CoV) and potential drugs that could be repurposed as COVID-19 treatments. The researchers suggest that repurposed pan-coronavirus therapeutics may offer a rapid treatment response against future emerging coronavirus strains (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 15, 2020 Category: Infectious Diseases Source Type: news

'Brain fog' following COVID-19 recovery may indicate PTSD
(University of California - Los Angeles Health Sciences) A new report suggests that lingering " brain fog " and other neurological symptoms after COVID -19 recovery may be due to post-traumatic stress disorder (PTSD), an effect observed in past human coronavirus outbreaks such as SARS and MERS. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 6, 2020 Category: Infectious Diseases Source Type: news

Persistence of SARS-CoV-2 in Aerosol Suspensions Persistence of SARS-CoV-2 in Aerosol Suspensions
How does the aerosol efficiency of SARS-CoV-2 compare with that of SARS-CoV and MERS-CoV?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 28, 2020 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

What are the effects of quarantine for close contacts of people with confirmed COVID19?, Cochrane Clinical Answers
Reviewers conducted a rapid review of the evidence on quarantine for close contacts of people with confirmed COVID ‐19 (plus isolation of the infected individual) and identified one observational study conducted in Singapore, along with eight modeling studies based on data collected from China, Singapore, the UK, the cruise ship Diamond Princess, or generic populations. Studies reported that quarantine for clo se contacts decreased the incidence of COVID‐19, mortality, and resource use (such as hospitalization and numbers of doctors and nurses needed in intensive care units). Reviewers rated the certainty of all eviden...
Source: Current Awareness Service for Health (CASH) - September 24, 2020 Category: Consumer Health News Source Type: news

Roche launches new quantitative antibody test to measure SARS-CoV-2 antibodies, to support the evaluation of vaccines
Basel, 18 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced the launch of its Elecsys ® Anti-SARS-CoV-2 S antibody test for markets accepting the CE Mark. Roche has filed for Emergency Use Authorisation (EUA) from the U.S. Food and Drug Administration (FDA). The Elecsys Anti-SARS-CoV-2 serology test can be used to quantitatively measure antibodies in people who have been exposed to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and can play an important part in characterising a vaccine-induced immune response.1 Specifically, the test targets antibodies which are directed against the ...
Source: Roche Media News - September 18, 2020 Category: Pharmaceuticals Source Type: news

Roche launches new quantitative antibody test to measure SARS-CoV-2 antibodies, to support the evaluation of vaccines
Basel, 18 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced the launch of its Elecsys ® Anti-SARS-CoV-2 S antibody test for markets accepting the CE Mark. Roche has filed for Emergency Use Authorisation (EUA) from the U.S. Food and Drug Administration (FDA). The Elecsys Anti-SARS-CoV-2 serology test can be used to quantitatively measure antibodies in people who have been exposed to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and can play an important part in characterising a vaccine-induced immune response.1 Specifically, the test targets antibodies which are directed against the ...
Source: Roche Investor Update - September 18, 2020 Category: Pharmaceuticals Source Type: news

Progress toward antiviral treatments for COVID-19
COVID-19 is caused by a virus known as SARS-CoV-2, which is similar in structure to two other viruses that have caused recent outbreaks: SARS-CoV, which caused an outbreak of SARS in 2003, and MERS-CoV, the cause of a 2012 outbreak of Middle East Respiratory Syndrome. (Source: World Pharma News)
Source: World Pharma News - September 15, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Progress toward antiviral treatments for COVID-19
(American Institute of Physics) COVID-19 is caused by the virus SARS-CoV-2, which is structurally similar to the viruses that cause SARS-CoV and MERS-CoV. In The Journal of Chemical Physics, scientists report molecular-level investigations of these viruses, providing a possible pathway to antiviral drugs to fight the diseases. They looked at a viral protein that plays a role in the virus's ability to replicate and in defeating the host's immune system, making it an attractive target for potential drug treatments. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 15, 2020 Category: Infectious Diseases Source Type: news

Cochrane Rapid Review examines travel-related control measures to contain the COVID-19 pandemic
 Can travel-related control measures contain the spread of the COVID-19 pandemic?What are travel-related control measures?To contain the spread of COVID-19, numerous countries have implemented control measures related to international travel. These include:complete closure of borders (i.e. a total ban on any border crossings);partial travel restrictions (e.g. restrictions on air travel only, or restrictions on travellers from certain countries);entry or exit screening (e.g. when travellers are asked about symptoms, examined physically, or tested for infection when leaving or entering a country);quarantine of traveller...
Source: Cochrane News and Events - September 10, 2020 Category: Information Technology Authors: Muriah Umoquit Source Type: news

The Great Vaccine Race: Inside the Unprecedented Scramble to Immunize the World Against COVID-19
The cleverest of enemies thrive on surprise attacks. Viruses—and coronaviruses in particular—know this well. Remaining hidden in animal hosts for decades, they mutate steadily, sometimes serendipitously morphing into more effective and efficient infectious agents. When a strain with just the right combination of genetic codes that spell trouble for people makes the leap from animal to human, the ambush begins. Such was the case with SARS-CoV-2, the coronavirus behind COVID-19, and the attack was mostly silent and insidious at first. Many people infected with SARS-CoV-2 remained oblivious as they served as the v...
Source: TIME: Health - September 10, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Magazine Source Type: news

Roche receives FDA Emergency Use Authorization for the cobas SARS-CoV-2 & Influenza A/B Test for use on the cobas 6800/8800 Systems
Basel, 04 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the cobas ® SARS-CoV-2& Influenza A/B Test for use on the cobas ® 6800/8800 Systems has received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA). This test is intended for the simultaneous qualitative detection and differentiation of SARS-CoV-2, Influenza A and Influenza B in patients suspected by their healthcare provider of having respiratory viral infection consistent with COVID-19. Additionally, it is available in markets accepting the CE mark.“With the approaching flu season, this new...
Source: Roche Media News - September 4, 2020 Category: Pharmaceuticals Source Type: news

Roche receives FDA Emergency Use Authorization for the cobas SARS-CoV-2 & Influenza A/B Test for use on the cobas 6800/8800 Systems
Basel, 04 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the cobas ® SARS-CoV-2& Influenza A/B Test for use on the cobas ® 6800/8800 Systems has received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA). This test is intended for the simultaneous qualitative detection and differentiation of SARS-CoV-2, Influenza A and Influenza B in patients suspected by their healthcare provider of having respiratory viral infection consistent with COVID-19. Additionally, it is available in markets accepting the CE mark.“With the approaching flu season, this new...
Source: Roche Investor Update - September 4, 2020 Category: Pharmaceuticals Source Type: news

Plasmin could be the link between COVID-19 comorbidities and serious illness
(University of Alabama at Birmingham) Why is the COVID-19 virus more dangerous in people with comorbidities? Literature analysis shows that comorbidities like hypertension, diabetes, coronary heart disease, cerebrovascular illness, chronic obstructive pulmonary disease and kidney dysfunction all feature elevated levels of the extracellular protease plasmin. Plasmin is able to nick proteins sequences called furin sites. For many viruses, this nicking increases viral infectivity, including SARS and MERS -- the two virulent coronaviruses that are related to the COVID-19 virus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news

High rates of delirium, persistent fatigue and post-traumatic stress disorder were common after severe infection in previous coronavirus outbreaks, NIHR
Little is known about the mental health consequences of severe COVID-19 illness because it is caused by a new coronavirus. Previous outbreaks caused by other coronaviruses (severe acute respiratory syndrome, SARS, and Middle East respiratory syndrome, MERS) may provide insights into ongoing problems after recovery from severe illness. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 28, 2020 Category: Consumer Health News Source Type: news