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Nigeria: Lassa Fever Will Keep Ravaging Nigeria Unless Better Surveillance Is Put in Place
[The Conversation Africa] Lassa fever was first discovered nearly 50 years ago in Nigeria. Since then, it has been reported in other West African countries including Sierra Leone, Liberia and Guinea. There is also evidence of Lassa fever presence in southern Mali, Burkina Faso, C ôte d'Ivoire and Ghana, all of which share a similar tropical wooded savanna ecological zone. But there is still no vaccine against the disease. A new outbreak in 19 Nigerian states and in Lagos city - the most populated city on the continent - has sp (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 26, 2017 Category: African Health Source Type: news

Nigeria: NCDC Reports Suspected Cases of Cholera, Lassa Fever, Others
[Vanguard] A total of 253 new cases of Acute Flaccid Paralysis, AFP, were reported in Nigeria in the week ending August 27, 2017, according to the Nigeria Centres for Diseases Control, NCDC, however, none was confirmed as polio. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 26, 2017 Category: African Health Source Type: news

Nigeria: 15 Contracted, One Under Surveillance After Lassa Fever Outbreak in Kogi
[This Day] Lokoja -The Kogi State Commissioner for Health, Dr. Saka Audu has disclosed that the late Aisha Jimoh, who died of Lassa fever contacted 15 persons, adding that out of the number, one person is under surveillance. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 6, 2017 Category: African Health Source Type: news

Nigeria: Kogi Lassa Fever Patient Dies
[Premium Times] A woman in Kogi, Aisha Jimoh, who was confirmed to have contracted the dreaded Lassa fever, is dead. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 5, 2017 Category: African Health Source Type: news

Researchers develop Lassa fever treatment effective eight days after infection
(University of Texas Medical Branch at Galveston) A collaborative team of scientists, led by a group at The University of Texas Medical Branch at Galveston, have successfully protected nonhuman primates against one of the most deadly viruses in the world, Lassa fever, eight days after they became infected. The findings are now available in Nature Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 5, 2017 Category: International Medicine & Public Health Source Type: news

Nigeria: Lasser Fever - LUTH Discharges 150 - Watching 40 Others
[Vanguard] The Lagos University Teaching Hospital, LUTH, yesterday said it has discharged 150 of its personnel placed under surveillance for Lassa fever following an outbreak that left two persons dead and five doctors infected. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 31, 2017 Category: African Health Source Type: news

Nigeria: Alarming Shortage of Health Personnel in Conflict-Affected Nigeria
[UNFPA] Maiduguri -Retired but not tired. This is how people describe Hauwa Lassa, a nurse and midwife who came out of retirement to care for women and girls affected by the conflict in north-eastern Nigeria. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 30, 2017 Category: African Health Source Type: news

Alarming shortage of health personnel in conflict-affected Nigeria
Language EnglishMAIDUGURI, Nigeria –Retired but not tired. This is how people describe Hauwa Lassa, a nurse and midwife who came out of retirement to care for women and girls affected by the conflict in north-eastern Nigeria.“I have been working in the field of maternal health in this country for more than 35 years,” she told UNFPA in Maiduguri, where she works at a health facility in one of the displacement camps. “It is now with this crisis going on that the women need support. So I decided to come back to the h ealth centre and help.” (Source: UNFPA News)
Source: UNFPA News - August 29, 2017 Category: International Medicine & Public Health Authors: zerzan Source Type: news

Nigeria: Herbal Defense Against Viral Infections
[Guardian] Re-emerging infectious diseases such as Lassa fever, yellow fever, Ebola, measles, chicken pox, small pox, Dengue fever, viral hepatitis, Human Immuno-deficiency Virus (HIV), polio, cold and influenza virus, among others are posing fresh threat to human existence. Unfortunately, conventional medicines are failing: the pathogens have developed resistance to the drugs-of-choice. But researchers have in experimental models treated these deadly bugs with combination of local herbs and spices. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 24, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever - Minister of State for Health Calls for Urgent Review Action
[Daily Trust] The Minister of State for Health, Dr Osagie Ehanire has said there is urgent need to review actions taken before and during the outbreak of Lassa fever so as to improve the country's level of preparedness and response to epidemic outbreaks. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 22, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever Kills 68, 718 Cases Recorded
[Leadership] Abuja -About 68 persons have been killed by lassa fever since the begining of 2017, the Federal Government has said. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 22, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever Claims One Life in Kwara, Lagos Records New Case
[Vanguard] Kwara State government has said that Lassa fever has claimed the life of one person in the state. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 19, 2017 Category: African Health Source Type: news

Nigeria: Halt Lassa Fever in Its Tracks
[Daily Trust] Lassa fever, one of this country's most dreaded contagious diseases, recently resurfaced in several states all at once. It made a deadly appearance at the Lagos University Teaching Hospital where two patients died and 15 others have been infected. Lassa fever virus is known to be transmitted to human beings who eat food items contaminated with faeces or urine of rodents, mainly infected rats. Afterwards, any person who has physical contact with a Lassa fever infected person could also be infected. In this (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 17, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever - Osun Cautions Residents As Corpse Tests Positive to Virus ‎
[Premium Times] The Osun State Government on Tuesday urged its citizens to be vigilant and maintain high hygienic standards after a corpse which was brought from Lagos tested positive to Lassa. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 16, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever - High Alert As Ogun Confirms 1 Case
[Vanguard] Surveillance officers and health workers in Lagos and Ogun States have been placed on high alert, even as Ogun State confirmed 1 case of Lassa fever and the Lagos University Teaching Hospital, LUTH, assured that confirmed cases in the institution are responding to treatment. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 14, 2017 Category: African Health Source Type: news

Nigeria: How We Buried Lassa Fever Victim - LASG
[Vanguard] The corpse of the second Lassa fever victim simply identified as Mr Hope, that died within 24 hours after admission in the Lagos University Teaching Hospital, LUTH, has been buried, even as a 22-year-old male patient is undergoing medical observation for suspected Lassa fever at the Ogun State General Hospital, Ijaiye, Abeokuta.. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 11, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever - 3 More Test Positive At LUTH, 150 Under Watch
[Vanguard] Lagos -Three persons under surveillance for Lassa fever at the Lagos University Teaching Hospital, LUTH, have tested positive to the disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 10, 2017 Category: African Health Source Type: news

Nigeria: Panic As Luth Confirms Lassa Fever Outbreak in Lagos
[Guardian] There is the fear of an outbreak of Lassa fever in the country as the Lagos University Teaching Hospital (LUTH) yesterday confirmed that two patients treated have died within a few days of admission in the past one week. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 9, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever Kills Two in Lagos
[This Day] Two persons, including a 36-year-old pregnant woman, have died at the Lagos University Teaching Hospital (LUTH), Idi-Araba, after being treated for Lassa fever. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 9, 2017 Category: African Health Source Type: news

Nigeria: NMA Alerts Nigerians On Ebola, Lassa Fever
[Daily Trust] The Nigerian Medical Association (NMA) has alerted Nigerians on the need to raise their guard against another outbreak of Lassa fever and Ebola. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 11, 2017 Category: African Health Source Type: news

Tulane University awarded $12 million to create Lassa vaccine and treatment
(Tulane University) The National Institutes of Health has awarded Tulane University more than $12 million to test a promising drug treatment against Lassa fever and develop a vaccine against the deadly disease endemic in parts of West Africa. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 11, 2017 Category: International Medicine & Public Health Source Type: news

Nigeria: 'No Case of Lassa Fever in Ogun'
[Daily Trust] Abeokuta -The Ogun State Commissioner for Health, Dr. Babatunde Ipaye has said that reports from the Diseases Surveillance Officers (DSO), across the 20 Local Government Areas and 37 Local Council Development Areas of the state have shown that there was no case of Lassa fever in the state. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 4, 2017 Category: African Health Source Type: news

Guidance Document: Questionnaire on Regulatory Science Issues for the Development of Emerging Infectious Disease (EID) Vaccines
Coalition for Epidemic Preparedness Innovations. 03/29/2017 This four-page document provides guidance on the completion of the CEPI questionnaire on regulatory science issues for development of emerging infectious disease (EID) vaccines. Partners with an interest in securing regulatory approval/licensure of EID vaccines are invited to provide comment on the regulatory scientific issues for the development of EID vaccines. The document provides background information and issues on the prioritized pathogens Ebola, Lassa, Nipah, and Middle East respiratory syndrome (MERS). (PDF) (Source: Disaster Lit: Resource Guide for Disas...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - July 2, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

WHO (World Health Organization) Target Product Profile for Lassa Virus Vaccine
World Health Organization. 06/2017 This 11-page document is a vaccine target product profile that followed prioritization of Lassa fever as part of the World Health Organization (WHO) R&D Blueprint for Action to Prevent Epidemics. The criteria lay out some of the considerations that will be relevant in WHO's case-by-case assessments of Lassa virus vaccines in the future. The profile considers two scenarios: non-emergency setting (preventive use), and emergency setting (reactive/outbreak use). (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - June 30, 2017 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news

Lassa Fever – Nigeria
Lassa fever is an acute viral haemorrhagic fever illness that is known to be endemic in various West African countries including Nigeria. As of 9 June 2017, a total of 501 suspected cases including 104 deaths have been reported since the onset of the current Lassa fever outbreaks season in December 2016. Of the reported cases, 189 have been further classified, 175 laboratory-confirmed including 59 deaths and 14 probable cases (all dead). (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - June 28, 2017 Category: Infectious Diseases Tags: news Source Type: news

Patient with Lassa Fever Offers Clues to Virus (CME/CE)
(MedPage Today) -- In-depth study probes neglected disease (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - June 22, 2017 Category: Infectious Diseases Source Type: news

Nigeria: Five Cases Confirmed As Lassa Fever Ravages Ondo
[Premium Times] The Lassa fever epidemic which started as a rumour some weeks ago in Ondo State, has fully manifested, with five persons now hospitalized for being infected with the disease. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 22, 2017 Category: African Health Source Type: news

Studies of US Lassa fever patient offer clues about immune response, viral persistence
(Infectious Diseases Society of America) Researchers were able to closely study a Lassa fever patient's immune response over time after he was evacuated to the US for treatment.An experimental drug, favipiravir, was used in treating the US patient and an additional patient infected with Lassa virus in Germany. The drug appeared to have few serious side effects, but its efficacy is unknown.Individual patient reports cannot be generalized to broader population, but findings suggest promising areas for future research. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 22, 2017 Category: Infectious Diseases Source Type: news

Nigeria: Lassa Fever Claims One, 65 On Surveillance in Anambra
[Daily Trust] Awka -A woman has been confirmed dead while 65 others are currently being monitored for Lassa fever in Anambra State, Director of Public Health, Ministry of Health (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 20, 2017 Category: African Health Source Type: news

Argonne X-rays used to help identify a key Lassa virus structure
(DOE/Argonne National Laboratory) Research done at Argonne National Laboratory's Advanced Photon Source was vital to the process of identifying the structure, which provides a guide for designing a Lassa virus vaccine. Lassa virus is endemic to Africa and kills thousands of people a year; it is particularly deadly for pregnant women. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 13, 2017 Category: International Medicine & Public Health Source Type: news

Details of Lassa virus structure could inform development of vaccines, therapies
Lassa virus can cause a hemorrhagic disease called Lassa fever and is endemic to western Africa. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - June 2, 2017 Category: American Health Source Type: news

Details of Lassa virus structure could inform development of vaccines, therapies
(NIH/National Institute of Allergy and Infectious Diseases) A 10-year Lassa virus research project has yielded structural and functional details of a key viral surface protein that could help advance development of Lassa vaccines and antibody-based therapeutics, which are currently lacking. The work was led by the Scripps Research Institute (TSRI) and funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 2, 2017 Category: International Medicine & Public Health Source Type: news

Perseverance pays off in fight against deadly Lassa virus
(Scripps Research Institute) This story starts with a young graduate student in San Diego and leads all the way to Sierra Leone, to a unique hospital where Lassa fever victims arrive by the thousands every year. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 1, 2017 Category: Infectious Diseases Source Type: news

A step on the path to a Lassa vaccine
(Source: ScienceNOW)
Source: ScienceNOW - June 1, 2017 Category: Science Authors: Vinson, V. Tags: Biochemistry twis Source Type: news

Structural basis for antibody-mediated neutralization of Lassa virus
The arenavirus Lassa causes severe hemorrhagic fever and a significant disease burden in West Africa every year. The glycoprotein, GPC, is the sole antigen expressed on the viral surface and the critical target for antibody-mediated neutralization. Here we present the crystal structure of the trimeric, prefusion ectodomain of Lassa GP bound to a neutralizing antibody from a human survivor at 3.2-angstrom resolution. The antibody extensively anchors two monomers together at the base of the trimer, and biochemical analysis suggests that it neutralizes by inhibiting conformational changes required for entry. This work illumin...
Source: ScienceNOW - June 1, 2017 Category: Science Authors: Hastie, K. M., Zandonatti, M. A., Kleinfelter, L. M., Heinrich, M. L., Rowland, M. M., Chandran, K., Branco, L. M., Robinson, J. E., Garry, R. F., Saphire, E. O. Tags: Biochemistry r-articles Source Type: news

Wash. Hospital Conducts Ebola Simulation at New Special Pathogens Unit
Spokane, Wash. - Sacred Heart Medical Center was the hospital selected for the Washington, Oregon, Alaska and Idaho region to receive a $2.1 million grant from the U.S. Department of Health and Human Services to build a new special pathogens unit. Hospital staff can care for two Ebola patients or up to 10 patients with other highly infectious diseases. Paramedics wore waterproof suits with respirators as they unloaded a patient at the Sacred Heart Medical Center parking garage Wednesday morning. The back of the ambulance had been covered in plastic from floor to ceiling, and the patient was zipped into a plastic isolation ...
Source: JEMS: Journal of Emergency Medical Services News - May 18, 2017 Category: Emergency Medicine Authors: Rachel Alexander, The Spokesman-Review Tags: Training News Source Type: news

13 Dead From Unexplained Illness In Liberia
A mysterious illness has killed 13 people and sickened 30 others in Liberia since April 23, according to the World Health Organization. Dr. Alex Gasasira, the WHO’s representative in Liberia, told HuffPost on Saturday that while authorities have not found the “smoking gun” of what has caused the unexplained illnesses and deaths in Sinoe County, Grand Bassa County and the capital city of Monrovia, all signs seem to point to an accidental “poisoning event” of some sort. The WHO said on Friday that all tests have come back negative for Ebola or Lassa fever. Of those that have died, 12 attend...
Source: Healthy Living - The Huffington Post - May 6, 2017 Category: Consumer Health News Source Type: news

Lassa Fever – Benin, Togo and Burkina Faso
On 20 February 2017, the Ministry of Health of Benin notified WHO of a Lassa fever case in Tchaourou district, Borgou Department, Benin, close to the border with Nigeria. The case was a pregnant woman who was living in Nigeria (close to the border with Benin). (Source: WHO Disease Outbreaks)
Source: WHO Disease Outbreaks - March 10, 2017 Category: Infectious Diseases Tags: news Source Type: news

Nigeria: Borno Govt Confirms Lassa Fever Outbreak
[Daily Trust] Maiduguri -The Borno State Commissioner for Health, Dr. Haruna Mshelia, yesterday confirmed the outbreak of Lassa fever in Jere Local Government Area of the state. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 2, 2017 Category: African Health Source Type: news

Nigeria: Woman Dies of Lassa Fever in Cross River
[Premium Times] A 22-year old woman, Itodo Christabel, was on Wednesday confirmed dead from Lassa fever in Calabar, capital of Cross River State. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 23, 2017 Category: African Health Source Type: news

Nigeria: Seven New Cases of Lassa Fever Reported in Edo, Ondo, Bauchi
[This Day] Abuja -Seven new cases of Lassa fever have been reported in three states namely: Edo, Ondo, and Bauchi, with four, two and one cases respectively in the weekly report collated by the Nigeria Centre for Disease Control (NCDC). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 9, 2017 Category: African Health Source Type: news

Nigeria: Ogun Confirms Another 19 Lassa Fever Cases Negative
[This Day] Abeokuta -Ogun State Commissioner for Health, Dr. Babtunde Ipaye, monday disclosed that 19 suspected lassa fever patients who had close contacts with another new suspect came out negative in the lassa fever screen test. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 24, 2017 Category: African Health Source Type: news

[In Depth] A half-billion-dollar bid to head off emerging diseases
In the wake of the Ebola crisis that erupted in West Africa in 2014, many public health leaders recognized that a more aggressive effort to develop vaccines could have moved a vaccine forward more quickly and prevented that outbreak from becoming an epidemic. A new organization was formed last year, the Coalition for Epidemic Preparedness Innovations (CEPI), to speed development of vaccines against emerging infectious diseases—but it had no serious financial backing. Now, CEPI has attracted nearly a half-billion dollars in funding, as it planned to announce at the World Economic Forum in Davos, Switzerland, this...
Source: ScienceNOW - January 19, 2017 Category: Science Authors: Jon Cohen Tags: Public Health Source Type: news

Global Coalition Aims To Outpace Epidemics With New Vaccines
A global coalition of governments, health specialists and philanthropists will launch a new plan on Thursday to “outsmart” future disease epidemics with a fund to prepare and create new vaccines. Stung by the devastation of West Africa’s 2014-2015 Ebola outbreak, which killed more than 11,300 people before an effective vaccine was developed, the coalition is aiming to ensure such deadly outbreaks can’t happen again. John-Arne Rottingen, interim chief executive officer of the Coalition for Epidemic Preparedness Innovations (CEPI), said it is designed as “a global insurance policy against epidem...
Source: Healthy Living - The Huffington Post - January 19, 2017 Category: Consumer Health News Source Type: news

World leaders donate $500m to fast-track three vaccines
Bill Gates has joined the governments of Germany, Norway, and Japan in donating $460 million to make vaccines for Middle East respiratory syndrome coronavirus (MERS-CoV), Lassa and Nipah viruses. (Source: the Mail online | Health)
Source: the Mail online | Health - January 19, 2017 Category: Consumer Health News Source Type: news

$460m pledged for vaccine initiative aimed at preventing global epidemics
Lassa, Mers and Nipah will be first diseases targeted by programme announced at Davos by coalition of governments, philanthropists and businessA coalition of governments, philanthropists and business is pledging to put money and effort into making vaccines to stop the spread of diseases that could threaten mankind – and to prevent another outbreak as devastating as the Ebola epidemic.At theWorld Economic Forum in Davos, the Norwegian, Japanese and German governments, the Wellcome Trust and the Gates Foundation announced they were putting in $460 million – half of what is needed for the first five years of the i...
Source: Guardian Unlimited Science - January 18, 2017 Category: Science Authors: Sarah Boseley Health editor Tags: Vaccines and immunisation Infectious diseases Davos Health Epidemics Medical research Business Science Society World news Source Type: news

Nigeria: Lassa Fever - NCDC Confirms 9 Deaths, 20 Cases in 7 States
[Vanguard] The Nigeria Centre for Disease Control, NCDC, has confirmed nine deaths and 20 cases of Lassa Fever in seven states since the beginning of the dry season in December 2016; even as it commences implementation of its plan to strengthen nationwide response capacity to anticipated Lassa Fever cases. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 17, 2017 Category: African Health Source Type: news

Nigeria: Lassa Fever Kills Four in Nasarawa
[Premium Times] The Nasarawa State Commissioner for Health, Daniel Iya, has confirmed that four persons have lost their lives to Lassa fever outbreak in the state. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 17, 2017 Category: African Health Source Type: news

Nigeria: Centre Cautions Nigerians On Increased Lassa Fever Cases
[Premium Times] The Nigeria Centre for Disease Control, NCDC, on Monday raised concerns over the increasing cases of Lassa fever and urged increased focus on prevention and preparedness. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 17, 2017 Category: African Health Source Type: news

Nigeria: 2016 Records Highest Lassa Deaths
[Daily Trust] Lassa fever killed more people between 2015 and 2016, the highest death toll from the disease on record since it was discovered more than 40 years ago, says the Nigeria Centre for Disease Control, NCDC. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 28, 2016 Category: African Health Source Type: news