What’s the best way to quit smoking?
Smoking cigarettes contributes to almost 1 in 5 deaths. The top three smoking-related causes of death are cardiovascular disease, lung cancer, and chronic obstructive pulmonary disease (COPD). In addition to these “top three,” smoking is also linked to a number of other cancers, an increased likelihood of getting more colds and infections, diabetes, osteoporosis and hip fractures, problems in pregnancy, difficulty with erections, stomach ulcers, gum disease, and the list goes on. Quitting smoking can add years to your life. Though the earlier the better, it’s never too late to quit. The benefits of quitting are real, even at the age of 80! So what’s the best way to quit? Set a quit date Pick a date in the next few weeks, share it with your friends and your family, and mark it on your calendar. Plan to completely stop smoking on that quit date. Think about what might make it challenging to stop. Be prepared for how you will handle any withdrawal symptoms. Identify what triggers your craving for a cigarette, and have a strategy to avoid or deal with these triggers. Start exercising before your quit date to minimize weight gain when you stop smoking. Find healthy distractions to keep your mind and hands busy. Have nicotine replacement products like nicotine gum and patches ready on hand if you plan to use them. Going “cold turkey” might be better You can choose to cut down on your cigarettes gradually before your quit date, or smoke as you nor...
The Pallimed community is invited to participate in the #hpm Tweet Chat this week which help inform and shape a comparative effectiveness research proposal being designed by the Brain Cancer Quality of Life Collaborative, an initiative led by a team of patients, care partners, advocates, neuro-oncologists, and palliative care professionals.The #hpm Tweet Chat is this Wednesday, April 25th, 6-7p PST/9-10p ET.Topics for the chatare available here, in the #hpm chat ’s blog post,How might we introduce palliative care to people with complex neurological conditions, by Liz Salmi and Bethany Kwan, P...
This study included all patients with non-metastatic primary T1 UBC reported to the Swedish National Register of Urinary Bladder Cancer (SNRUBC) from 1997 to 2014, excluding those treated with primary cystectomy. Differences between groups were evaluated using chi-squared tests and logistic regression, and survival was investigated using Kaplan-Meier and log-rank tests and Cox proportional hazards analysis. RESULTS: In all, 7681 patients with T1 UBC (77% male, 23% female) were included. Females were older than males at the time of diagnosis (median age at presentation 76 and 74 years, respectively; p
If the lack of control in the ED, the unfairness &unrealistic expectations by administration, and the chaotic circadian rhythm disruption has depressed your attitude, self confidence and hope for the future and burned you out, I'm here to tell you, there is a better way. Maybe it's a new EM job, or simply cutting work hours. Maybe for someone else, it's another residency, a fellowship, leaving Medicine altogether or something entirely different. What it is for any specific individual, I... Go from burnout to recharged &energized
CONCLUSION: This first national survey revealed a high prevalence of mental disorders. Considering the importance of mental disorders in the general population, it is important to train and involve more nurses and general practitioners in the identification and management of these disorders as there are very few specialists in the field at present. PMID: 29673721 [PubMed - as supplied by publisher]
Conclusion: Significant changes in oxidative stress indicators were observed in this study, confirming previous studies. Increased levels of oxidants were shown with increased disease severity rather than with the number of manic episodes. Systematic studies, including of each period of the disorder, are needed for using the findings indicating deterioration of oxidative parameters. PMID: 29674601 [PubMed - as supplied by publisher]
Conclusion: An adolescent psychological autopsy study using the K-PAC-A is expected to provide useful evidence for suicide prevention policies and intervention plans for Korean youths in the future. PMID: 29674599 [PubMed - as supplied by publisher]
It appears the prescribing of Subsys in non-cancer patients is now considered a crime by the federal government. Las Vegas pain physician arrested for illegal fentanyl distribution: 5 things to know Written by Brian Zimmerman | February 19, 2018 www.beckershospitalreview.com Police arrested a Las Vegas pain management physician Feb. 13 for charges related to the unlawful distribution of fentanyl and healthcare fraud. Here... Subsys Rx for Non-cancer Patients Is Considered a Criminal Act
Authors: Gao Y, Xu Y, Wang J, Yang X, Wen L, Feng J Abstract Long noncoding RNAs (lncRNAs) have been acknowledged as important regulators in various human cancers. LncRNA MNX1-AS1has been shown to be an oncogene in epithelial ovarian cancer. However, the function of MNX1-AS1 in glioblastoma (GBM) remains largely unknown. Here, we found that the expression of MNX1-AS1 was significantly upregulated in GBM tissues and cell lines. Knockdown of MNX1-AS1 significantly inhibited the proliferation, migration and invasion of GBM cells. In terms of mechanism, we found that MNX1-AS1 could bind to miR-4443 in GBM cells. Overex...
This study also identified cordycepin derivatives with promising pharmacological and pharmacokinetic properties for further investigation in the development of new treatments for endometrial cancer. PMID: 29673423 [PubMed - as supplied by publisher]
Authors: Wang L, Li Q, Ye Z, Qiao B Abstract Renal carcinoma greatly threatens human health, but the involved molecular mechanisms are far from complete understanding. As a master oncogene driving the initiation of many other cancers, Pokemon has not been established to be associated with renal cancer. Our data revealed that Pokemon is highly expressed in renal carcinoma specimen and cell lines, compared with normal cells. The silencing of Pokemon suppressed the proliferation and invasion of renal cancer cells. Pokemon overexpression rendered normal cells with higher proliferation rates and invasiveness. Animal stu...
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