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Pravastatin Recalled Over Bupropion Mix-Up (FREE)
By the Editors One lot of pravastatin tablets (40 mg, 30-tablet bottles) manufactured by International Laboratories, LLC has … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 14, 2017 Category: Primary Care Source Type: news

International Laboratories, LLC Issues Voluntary Nationwide Recall of One (1) Lot of Pravastatin Sodium Tablets USP, 40mg Packaged in Bottles of 30 Tablets Due to Mislabeling NDC # 54458-925-16; Lot # 115698A
International Laboratories, LLC is voluntarily recalling one (1) Lot of Pravastatin Sodium Tablets USP 40 mg packaged in bottles of 30 tablets, to the consumer level due to mislabeling. The product is labeled as Pravastatin Sodium Tablets USP 40 mg but contained Bupropion Hydrochloride XL 300 mg tablets. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 10, 2017 Category: Food Science Source Type: news

For Treatment-Resistant Depression, Add an Antipsychotic or Switch Antidepressants? (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM For patients with depression unresponsive to antidepressants, adding the antipsychotic aripiprazole seems modestly better than switching to the antidepressant bupropion, a JAMA study … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 12, 2017 Category: Primary Care Source Type: news

Study compares switching meds vs. an additional med for patients unresponsive to an antidepressant
(The JAMA Network Journals) Among patients unresponsive to an antidepressant medication, adding the antipsychotic aripiprazole modestly increased the likelihood of remission from depression compared to switching to the antidepressant bupropion, according to a study published by JAMA. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 11, 2017 Category: International Medicine & Public Health Source Type: news

Jubilant Life Sciences gets USFDA nod for anti-depressive drug
The approved product is the generic version of Wellbutrin XL of Valeant, which is used for the treatment of major depressive disorder and prevention of seasonal affective disorder. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 6, 2017 Category: Pharmaceuticals Source Type: news

Cocaine abuse, traumatic brain injury, and preexisting brain lesions as risk factors for bupropion-associated psychosis - Barman R, Kumar S, Pagadala B, Detweiler MB.
BACKGROUND AND OBJECTIVE: Bupropion is generally considered safe and is widely used both as a monotherapy and as an augmentation agent for the treatment of major depression. Concerns have been raised about bupropion's propensity to precipitate new psychosi... (Source: SafetyLit)
Source: SafetyLit - June 9, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Orexigen Therapeutics Announces Commercialization and Distributorship Arrangement with Navamedic ASA for Mysimba(R) (naltrexone HCl / bupropion HCl prolonged release) in Five Nordic Countries
SAN DIEGO, May 2, 2017 -- (Healthcare Sales & Marketing Network) -- Orexigen Therapeutics, Inc. (NASDAQ: OREX) today announced that its wholly owned subsidiary, Orexigen Therapeutics Ireland Ltd., and Navamedic AB, an affiliate of Navamedic ASA (Oslo:NAVA... Biopharmaceuticals, Distribution Orexigen Therapeutics, Navamedic AB, Mysimba, naltrexone, bupropion (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 2, 2017 Category: Pharmaceuticals Source Type: news

Budeprion XL (Bupropion Hydrochloride Extended-Release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 8, 2017 Category: Drugs & Pharmacology Source Type: news

Smoking-Cessation Meds, Counseling Work in Patients With CVD Smoking-Cessation Meds, Counseling Work in Patients With CVD
In contrast with some earlier research, a meta-analysis found that varenicline and bupropion along with counseling by phone or in person all seem effective in patients with cardiovascular disease.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 24, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Aplenzin (Bupropion Hydrobromide Tablet) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 11, 2017 Category: Drugs & Pharmacology Source Type: news

Contrave (Naltrexone HCl and Bupropion HCl Extended-Release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 11, 2017 Category: Drugs & Pharmacology Source Type: news

La FDA revisa la descripci ó n de los efectos secundarios para la salud mental de los medicamentos para dejar de fumar Chantix (vareniclina) y Zyban (bupropi ó n) para reflejar las conclusiones de estudio cl í nico
FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 5, 2017 Category: Drugs & Pharmacology Source Type: news

La FDA revisa la descripci ón de los efectos secundarios para la salud mental de los medicamentos para dejar de fumar Chantix (vareniclina) y Zyban (bupropión) para reflejar las conclusiones de estudio clínico
FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 5, 2017 Category: Drugs & Pharmacology Source Type: news

Black Box Warnings Removed From Chantix, Zyban
(Source: WebMD Health)
Source: WebMD Health - December 19, 2016 Category: Consumer Health News Source Type: news

Health Highlights: Dec. 19, 2016
Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Black Box Warnings Removed From Chantix and Zyban The anti-smoking drug Chantix no longer has to carry a bold-letter warning about possible... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 19, 2016 Category: Journals (General) Source Type: news

FDA Drug Safety Communication: FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings
An FDA review found the side effects on mood, behavior, or thinking with the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) are lower than previously suspected. These risks still exist, but we believe the benefits of quitting smoking outweigh them. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 16, 2016 Category: Drugs & Pharmacology Source Type: news

Chantix, Zyban Lose Boxed Warning on Psych Effects
(MedPage Today) -- Labels will still note serious neuropsychiatric risk but without the black box (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - December 16, 2016 Category: American Health Source Type: news

How to Quit Smoking
By Stacy Simon Tobacco use remains the single largest preventable cause of disease and premature death in the United States. Since the release of the Surgeon General’s Report on Smoking and Health 50 years ago, there have been 20 million deaths due to tobacco. Almost half the deaths from 12 different types of cancer combined – including lung, voice box, throat, esophagus, and bladder cancers – are attributable to cigarette smoking alone. In addition to cancer, smoking greatly increases the risk of debilitating long-term lung diseases like emphysema and chronic bronchitis. It also raises the risk for heart...
Source: American Cancer Society :: News and Features - November 16, 2016 Category: Cancer & Oncology Tags: Smoking/Tobacco Source Type: news

Wellbutrin XL (Bupropion Hydrochloride Extended-Release) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 14, 2016 Category: Drugs & Pharmacology Source Type: news

Forfivo XL (Bupropion Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 10, 2016 Category: Drugs & Pharmacology Source Type: news

Varenicline and risk of self-harm: a nested case-control study - Tadrous M, Martins D, Yao Z, Mamdani MM, Juurlink DN, Gomes T, Antoniou T.
BACKGROUND: Smoking remains a serious public health concern. Pharmacotherapy for smoking cessation, including bupropion and varenicline, are proven means to increase quit rates. Post-marketing reports describing suicidal behaviours have raised concerns abo... (Source: SafetyLit)
Source: SafetyLit - November 8, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Orexigen Therapeutics Announces Commercialization and Distributorship Agreement with Valeant for Contrave(R) (naltrexone HCl / bupropion HCl extended release) in Australia and New Zealand
SAN DIEGO, Calif., Nov. 8, 2016 -- (Healthcare Sales & Marketing Network) -- Orexigen Therapeutics, Inc. (OREX) today announced that Valeant Pharmaceuticals International, Inc. (Valeant), through a wholly owned subsidiary, will commercialize Contrave®... Biopharmaceuticals, Distribution Orexigen Therapeutics, Valeant Pharmaceuticals, Contrave, naltrexone, bupropion (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 8, 2016 Category: Pharmaceuticals Source Type: news

Seizure due to multiple drugs intoxication: a case report - Gulec H, Babayigit M, Kurtay A, Sahap M, Ulus F, Tutal Z, Horasanli E.
The mechanism of the antidepressant effect of bupropion is not fully understood. Besides, using it in the treatment of depression, it is found to be effective in reducing withdrawal symptoms due to smoking cessation. A 28-year-old female patient with a his... (Source: SafetyLit)
Source: SafetyLit - November 6, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

UCLA awarded grant to study depression in older adults
More than half of older adults who are treated for depression find that eventually their treatments are no longer effective. When depression persists, these people are at greater risk of accelerated aging, declining mental health and even suicide.To help address this, UCLA and four other institutions have been awarded a $13.9 million grant to evaluate treatment strategies for older adults with depression who have not responded to medications. UCLA psychiatry professor Dr. Helen Lavretsky will serve as principal investigator on this new study.“No more than 30 to 40 percent of people respond to first-line treatments,&r...
Source: UCLA Newsroom: Health Sciences - September 30, 2016 Category: Universities & Medical Training Source Type: news

The relationship between bupropion and suicide in post-mortem investigations - Kriikku P, Ojanper ä I.
We reviewed the 33 727 postmortem toxicology investigations performed in Finland over a period of 5 years (2009-2013) and identified those in which the antidepressant bupropion was detected. Cases positive for other antidepressant drugs were reviewed for c... (Source: SafetyLit)
Source: SafetyLit - September 19, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

FDA Reviewers Question Chantix/Zyban Safety Study
(MedPage Today) -- Inclusion criteria and data collection criticized (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - September 13, 2016 Category: Primary Care Source Type: news

FDA Questions Validity of Smoking Cessation Drug Research FDA Questions Validity of Smoking Cessation Drug Research
The FDA has raised concerns about a postmarketing study that examined adverse neuropsychiatric events associated with smoking cessation drugs varenicline and bupropion.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 13, 2016 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Wellbutrin SR (Bupropion Hydrochloride Sustained-Release) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 9, 2016 Category: Drugs & Pharmacology Source Type: news

Weight Loss Pills And Products Don't Work And Aren't Safe
Our ancestors lived in a feast or famine world. When you don't know where your next meal is coming from, or when it will arrive, the smart play is to pig out every time food is available. Our genes are programmed to extract as much energy as possible from what we eat and to store any extra energy in fat reservoirs, available in reserve for future famines. These deeply ingrained genetic tendencies worked great in the austere world of our ancestors, but are a disaster in our current world of refrigerators, ubiquitous fast food joints and milk shakes. Only one third of Americans are now able to maintain a normal weight; one ...
Source: Science - The Huffington Post - September 5, 2016 Category: Science Source Type: news

Cipla gets USFDA nod for generic anti-depressant drug
The company's tablets are generic versions of Valeant's Wellbutrin XL tablets in the same strengths, Cipla said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 30, 2016 Category: Pharmaceuticals Source Type: news

Bupropion "abuse" reported to US poison centers - Stassinos GL, Klein-Schwartz W.
The objective was to determine the prevalence, characteristics, clinical effects, and outcomes of bupropion "abuse." METHODS: A 14-year retrospective review was conducte... (Source: SafetyLit)
Source: SafetyLit - August 12, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Orexigen Completes Acquisition of All U.S. Rights to Contrave(R) and Launches U.S. Sales Organization
SAN DIEGO, Aug. 1, 2016 -- (Healthcare Sales & Marketing Network) -- Orexigen Therapeutics (OREX) announced today that it has successfully completed its previously announced acquisition of the United States rights to Contrave® (naltrexone HCl/bupropio... Biopharmaceuticals, Acquisitions, Product Launch Orexigen Therapeutics, Contrave, naltrexone, bupropion (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 1, 2016 Category: Pharmaceuticals Source Type: news

Talk to your doctor about quitting smoking while pregnant
HealthDay News Use of nicotine patches or the drug Zyban helps pregnant women quit smoking before and after they give birth, a new study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 28, 2016 Category: Consumer Health News Source Type: news

Quitting Smoking While Pregnant: What Works
Nicotine patches, Zyban helped 4 out of 5 women, study says (Source: WebMD Health)
Source: WebMD Health - July 27, 2016 Category: Consumer Health News Source Type: news

Quitting Smoking While Pregnant: What Works
Nicotine patches, Zyban helped 4 out of 5 women, study saysSource: HealthDay Related MedlinePlus Pages: Pregnancy and Medicines, Pregnancy and Substance Abuse, Smoking (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 27, 2016 Category: Consumer Health News Source Type: news

Quitting Smoking While Pregnant: What Works
WEDNESDAY, July 27, 2016 -- Use of nicotine patches or the drug Zyban helps pregnant women quit smoking before and after they give birth, a new study says. " In public health terms, these results are significant because one in five pregnant women... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 27, 2016 Category: Journals (General) Source Type: news

Quitting smoking during the second half of the menstrual cycle may help women kick the habit
Follow me on twitter @hricciot Nearly every woman will acknowledge that her menstrual cycle affects her mood and behavior. An estimated 85% of women experience premenstrual syndrome one to two weeks before her period, which may include moodiness, anxiety, irritability, or food cravings along with physical symptoms such as bloating and breast tenderness. Studies suggest that women are more likely to engage in addictive behaviors, such as cigarette smoking, in the first half of the menstrual cycle, that is the time between the start of your period and ovulation. The underlying reason is thought to be that the hormone estradi...
Source: New Harvard Health Information - July 21, 2016 Category: Consumer Health News Authors: Hope Ricciotti, MD Tags: Addiction Behavioral Health Prevention Smoking cessation Women's Health Source Type: news

Quitting smoking during pregnancy: Beneficial for both mother and child
(University of Montreal) The results of a study, published in the American Journal of Obstetrics and Gynecology, indicate that in 80 percent of cases, women who used nicotine patches or the drug Zyban successively quit smoking. Even after stopping the use of these products, 60 percent of Zyban users and 68 percent of women using nicotine patches did not restart smoking during or after pregnancy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 19, 2016 Category: Global & Universal Source Type: news

What’s the best way to quit smoking?
Smoking cigarettes contributes to almost 1 in 5 deaths. The top three smoking-related causes of death are cardiovascular disease, lung cancer, and chronic obstructive pulmonary disease (COPD). In addition to these “top three,” smoking is also linked to a number of other cancers, an increased likelihood of getting more colds and infections, diabetes, osteoporosis and hip fractures, problems in pregnancy, difficulty with erections, stomach ulcers, gum disease, and the list goes on. Quitting smoking can add years to your life. Though the earlier the better, it’s never too late to quit. The benefits of quitti...
Source: New Harvard Health Information - July 8, 2016 Category: Consumer Health News Authors: Wynne Armand, MD Tags: Addiction Behavioral Health Lung disease Prevention Smoking cessation Source Type: news

What ’s the best way to quit smoking?
Smoking cigarettes contributes to almost 1 in 5 deaths. The top three smoking-related causes of death are cardiovascular disease, lung cancer, and chronic obstructive pulmonary disease (COPD). In addition to these “top three,” smoking is also linked to a number of other cancers, an increased likelihood of getting more colds and infections, diabetes, osteoporosis and hip fractures, problems in pregnancy, difficulty with erections, stomach ulcers, gum disease, and the list goes on. Quitting smoking can add years to your life. Though the earlier the better, it’s never too late to quit. The benefits of quitti...
Source: New Harvard Health Information - July 8, 2016 Category: Consumer Health News Authors: Wynne Armand, MD Tags: Addiction Behavioral Health Lung disease Prevention Smoking cessation Source Type: news

5 weight loss drugs that actually work in the US
Scientists at the University of California found of the drugs - orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide - the last two, marketed as Qsymia, Saxenda and Victoza were most effective. (Source: the Mail online | Health)
Source: the Mail online | Health - June 15, 2016 Category: Consumer Health News Source Type: news

Revealed... the 5 weight loss drugs that ACTUALLY work - helping obese people shed up to 20lbs in a year
Scientists at the University of California found of the drugs - orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide - the last two, marketed as Qsymia, Saxenda and Victoza were most effective. (Source: the Mail online | Health)
Source: the Mail online | Health - June 14, 2016 Category: Consumer Health News Source Type: news

Study compares effectiveness of weight-loss drugs
In an analysis that included nearly 30,000 overweight or obese adults, compared with placebo, orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide were each associated with achieving at least 5 percent weight loss at 52 weeks, and phentermine-topiramate and liraglutide were associated with the highest odds of achieving at least 5 percent weight loss, according to a study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 14, 2016 Category: Science Source Type: news

Zyban (Bupropion Hcl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 9, 2016 Category: Drugs & Pharmacology Source Type: news

World No Tobacco Day 2016
31 May is World No Tobacco Day. It is organized by the World Health Organization to draw attention to the health risks associated with the use of tobacco and what can still be done to reduce tobacco consumption around the world.Here we focus on a Cochrane Review of a medical intervention - nicotine receptor partial agonists for smoking cessation - and what the available evidence tells us about its effectiveness. Cochrane Review provides more support for medication as long-term aid to quitting smokingWhen people stop smoking, they experience cravings to smoke and unpleasant mood changes. Nicotine receptor partial agonists a...
Source: Cochrane News and Events - May 31, 2016 Category: Information Technology Authors: mumoquit at cochrane.org Source Type: news

Bupropion Only Antidepressant Linked to Weight LossBupropion Only Antidepressant Linked to Weight Loss
Bupropion was the only antidepressant associated with modest long-term weight loss over 2 years, but only among nonsmokers, a new study indicates. Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - May 17, 2016 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Wellbutrin (Bupropion Hcl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 9, 2016 Category: Drugs & Pharmacology Source Type: news

Elevated Psychiatric Risk Not Observed with Varenicline and Bupropion (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH The smoking cessation medications varenicline and bupropion aren't associated with increased risk for moderate-to-severe neuropsychiatric adverse events, suggests an industry-funded study requested by the FDA. Both drugs carry a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - April 24, 2016 Category: Primary Care Source Type: news

Stop smoking drugs not linked to rise in psychiatric side effects
Varenicline and bupropion do not increase rates of depression, anxiety or suicide ideation Related items from OnMedicaCombining varenicline with nicotine patch boosts quit ratesHospitals ‘should provide free e-cigarettes to patients’Teens who vape, likely to try the real thing a year onTobacco giants start legal challenge against plain packaging in UKStop smoking drug not linked to heart attacks or depression (Source: OnMedica Latest News)
Source: OnMedica Latest News - April 24, 2016 Category: UK Health Source Type: news

Chantix, Wellbutrin Found Safe in Smokers with Psych Disorders (CME/CE)
(MedPage Today) -- No increase in psychiatric adverse events for drug, patch users versus placebo (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 24, 2016 Category: Primary Care Source Type: news