Pre-Ozempic Obesity Drugs: Effective and Budget-Friendly
Before there was Ozempic, there were these cost-friendly, safe, and highly effective weight loss drugs. FDA-approved obesity medication like orlistat (Xenical), phentermine/topiramate (Qsymia), and naltrexone/bupropion extended release (Contrave) have been on the market for decades. (Source: WebMD Health)
Source: WebMD Health - April 26, 2024 Category: Consumer Health News Source Type: news

Novel Agent Curbs Alzheimer's-Related Agitation Novel Agent Curbs Alzheimer's-Related Agitation
AXS-05, a combination of dextromethorphan and bupropion, led to a rapid and sustained improvement in agitation related to Alzheimer ' s disease in the phase 3 ACCORD trial.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - April 23, 2024 Category: Internal Medicine Tags: Neurology & Neurosurgery News Source Type: news

Alzheimer's Agitation Relapse Delayed With Dextromethorphan-Bupropion
(MedPage Today) -- DENVER -- Dextromethorphan-bupropion (known as AXS-05) delayed time to relapse in patients with Alzheimer's-related agitation, according to a phase III trial presented here. Compared with placebo, AXS-05 increased the time... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 17, 2024 Category: Psychiatry Source Type: news

Agitation Relapse Delayed With Dextromethorphan-Bupropion
(MedPage Today) -- DENVER -- Dextromethorphan-bupropion (known as AXS-05) delayed time to relapse in patients with Alzheimer's-related agitation, according to a phase III trial presented here. Compared with placebo, AXS-05 increased the time... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 17, 2024 Category: Psychiatry Source Type: news

Elon Musk suggests his prescription ketamine use is good for investors
In a new interview, Elon Musk said prescription ketamine has been helpful in treating his occasional depressive episodes and suggested that taking the drug has been beneficial for investors in his companies. Musk, speaking with former CNN anchor Don Lemon in an interview that was posted online…#elonmusk #donlemon #tesla #lemon #austin #tulsigabbard #jimrome #wellbutrin #matthewperry #donlemonshow (Source: Reuters: Health)
Source: Reuters: Health - March 18, 2024 Category: Consumer Health News Source Type: news

Singer, 19, claims antidepressants changed her SEXUALITY: 'I took out my nose piercing and got rid of my pink hair... I've never been happier!'
June Henry, 19, from Lawrence, Kansas, said within weeks of starting a course of Wellbutrin she began questioning her sexuality. Henry was in a polymerous relationship before her prescription. (Source: the Mail online | Health)
Source: the Mail online | Health - December 4, 2023 Category: Consumer Health News Source Type: news

GI Adverse Events Increased With Use of GLP-1 Agonists for Weight Loss
FRIDAY, Oct. 6, 2023 -- Use of glucagon-like peptide 1 (GLP-1) receptor agonists for weight loss is associated with increased risks for pancreatitis, gastroparesis, and bowel obstruction compared with use of bupropion-naltrexone, according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 6, 2023 Category: Pharmaceuticals Source Type: news

GLP-1 Agonists Linked to Higher Risk for GI Complications GLP-1 Agonists Linked to Higher Risk for GI Complications
Compared with naltrexone/bupropion for weight loss, semaglutide and liraglutide were associated with a higher risk for three adverse gastrointestinal outcomes.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - October 5, 2023 Category: Drugs & Pharmacology Tags: Gastroenterology News Source Type: news

La FDA revisa la descripci ón de los efectos secundarios para la salud mental de los medicamentos para dejar de fumar Chantix (vareniclina) y Zyban (bupropión) para reflejar las conclusiones de estudio clínico
FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 25, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA Drug Safety Communication: FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings
An FDA review found the side effects on mood, behavior, or thinking with the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) are lower than previously suspected. These risks still exist, but we believe the benefits of quitting smoking outweigh them. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 11, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Prolonged Antidepressant Treatment No Benefit in Bipolar I Disorder
THURSDAY, Aug. 3, 2023 -- For patients with bipolar I disorder who had recently had remission of a depressive episode, adjunctive treatment with escitalopram or bupropion XL that continues for 52 weeks does not show a significant benefit compared... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 3, 2023 Category: Pharmaceuticals Source Type: news

A New Genetic Test Could Determine Which Weight Loss Drug Will Actually Work For You
As popular as the latest drugs being touted for weight loss, including Ozempic, Mounjaro, and Wegovy, are on social media, like any medications, they don’t work in the same way for everyone. Not all are even approved to treat obesity, but are being used off label as a relatively easy way to shed pounds. While some users lose up to 20% or more of their body weight on these drugs, others struggle to shed single digit percentages. That shouldn’t come as a surprise, since obesity isn’t a monolith and the factors that contribute to extra pounds are different for different people. In the same way that cancer do...
Source: TIME: Health - June 30, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate Weight loss Source Type: news

Adaptation to Pharmacotherapy Does Not Up Smoking Cessation in Black Adults
TUESDAY, June 27, 2023 -- For Black adults who smoke, adaptation to varenicline and/or bupropion plus nicotine patch (NP) does not improve abstinence rates compared with NP monotherapy, according to a study published online June 20 in JAMA Network... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 27, 2023 Category: Pharmaceuticals Source Type: news

The role of decision tree and machine learning models for outcome prediction of bupropion exposure: a nationwide analysis of more than 14,000 patients in the United States - Mehrpour O, Saeedi F, Vohra V, Abdollahi J, Shirazi FM, Goss F.
Bupropion is widely used for the treatment of major depressive disorder and for smoking cessation assistance. Unfortunately, there are no practical systems to assist clinicians or poison centers in predicting outcomes based on clinical features. Hence, the... (Source: SafetyLit)
Source: SafetyLit - March 28, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment-resistant depression and psychiatric comorbidities - Pedraz-Petrozzi B, Deuschle M, Gilles M.
We admitted a 42-year-old patient with severe treatment-resistant depression and with psychiatric comorbidities. The patient attempted suicide 5  weeks after admission. Subsequently, we initiated dextromethorphan/bupropion based on prior evidence. As a re... (Source: SafetyLit)
Source: SafetyLit - March 20, 2023 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news