Log in to search using one of your social media accounts:

 

Identification and characteristics of time-related shifts in suicide-related event frequency during smoking cessation treatment with varenicline - Akimoto H, Wakiyama H, Oshima S, Negishi A, Ohara K, Numajiri S, Okita M, Ohshima S, Inoue N, Kobayashi D.
OBJECTIVES: To survey time-related shifts in number of suicide-related events (SRE) during smoking cessation treatment with varenicline (VAR) in cases from the U.S. Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS), as well as the c... (Source: SafetyLit)
Source: SafetyLit - September 22, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

A Single Drug Could One Day Treat Pain, Memory Loss And Nicotine Addiction
Pain, memory problems and nicotine addiction are formidable problems that have quite different consequences. But in terms of what’s happening in the brain that causes people to suffer from each, they share a close connection. And now scientists say one drug might be able to help people with all three of these problems. Estimates suggest 2 million people in the U.S. suffered from an opioid abuse disorder in 2015 (the most recent year with data available), about 5 million Americans are currently living with Alzheimer’s disease and more than 36 million Americans are currently cigarette smokers (more than half of w...
Source: Healthy Living - The Huffington Post - May 31, 2017 Category: Consumer Health News Source Type: news

A Single Drug Could One Day Treat Pain, Memory Loss And Nicotine Addiction
Pain, memory problems and nicotine addiction are formidable problems that have quite different consequences. But in terms of what’s happening in the brain that causes people to suffer from each, they share a close connection. And now scientists say one drug might be able to help people with all three of these problems. Estimates suggest 2 million people in the U.S. suffered from an opioid abuse disorder in 2015 (the most recent year with data available), about 5 million Americans are currently living with Alzheimer’s disease and more than 36 million Americans are currently cigarette smokers (more than half of w...
Source: Science - The Huffington Post - May 31, 2017 Category: Science Source Type: news

Researchers warn of hazards of smoking and need for wider use of varenicline to quit
More than 35 million Americans are trying to quit smoking. Researchers reassure clinicians and their patients that varenicline, whose brand name is Chantix, is a safe and effective way to achieve smoking cessation and that failure to use this drug has caused preventable heart attacks and deaths from cardiovascular disease. Just a few months ago, the FDA removed the black box warning from varenicline. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 27, 2017 Category: Science Source Type: news

Researchers warn of hazards of smoking and need for wider use of varenicline to quit
(Florida Atlantic University) More than 35 million Americans are trying to quit smoking. Researchers reassure clinicians and their patients that varenicline, whose brand name is Chantix, is a safe and effective way to achieve smoking cessation and that failure to use this drug has caused preventable heart attacks and deaths from cardiovascular disease. Just a few months ago, the FDA removed the black box warning from varenicline. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 27, 2017 Category: Global & Universal Source Type: news

Smoking Cessation Drug May Boost Cognition in Schizophrenia Smoking Cessation Drug May Boost Cognition in Schizophrenia
The smoking cessation drug varenicline may help treat cognitive deficits in schizophrenia patients who smoke and allay worsening cognition when they try to quit.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 16, 2017 Category: Psychiatry Tags: Psychiatry News Source Type: news

Smoking-Cessation Meds, Counseling Work in Patients With CVD Smoking-Cessation Meds, Counseling Work in Patients With CVD
In contrast with some earlier research, a meta-analysis found that varenicline and bupropion along with counseling by phone or in person all seem effective in patients with cardiovascular disease.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 24, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

A combination of naltrexone + varenicline retards the expression of a genetic predisposition toward high alcohol drinking - Froehlich JC, Fischer SM, Nicholson ER, Dilley JE, Filosa NJ, Smith TN, Rademacher LC.
This study examined whether naltrexone (NTX) or varenicline (VAR), alone or in combination, can retard the phenotypic expression of a genetic predisposition toward high alcohol drinking in rats selectively bred for high alcohol intake when drug... (Source: SafetyLit)
Source: SafetyLit - January 14, 2017 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

La FDA revisa la descripci ó n de los efectos secundarios para la salud mental de los medicamentos para dejar de fumar Chantix (vareniclina) y Zyban (bupropi ó n) para reflejar las conclusiones de estudio cl í nico
FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 5, 2017 Category: Drugs & Pharmacology Source Type: news

La FDA revisa la descripci ón de los efectos secundarios para la salud mental de los medicamentos para dejar de fumar Chantix (vareniclina) y Zyban (bupropión) para reflejar las conclusiones de estudio clínico
FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 5, 2017 Category: Drugs & Pharmacology Source Type: news

FDA Smokes Black Box Warning on Chantix FDA Smokes Black Box Warning on Chantix
Siding with an advisory committee, the FDA approved dropping the black box warning regarding possible serious neuropsychiatric side effects with Pfizer's smoking cessation drug varenicline.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - December 19, 2016 Category: Psychiatry Tags: Psychiatry News Source Type: news

Black Box Warnings Removed From Chantix, Zyban
(Source: WebMD Health)
Source: WebMD Health - December 19, 2016 Category: Consumer Health News Source Type: news

Health Highlights: Dec. 19, 2016
Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Black Box Warnings Removed From Chantix and Zyban The anti-smoking drug Chantix no longer has to carry a bold-letter warning about possible... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 19, 2016 Category: Journals (General) Source Type: news

FDA Removes Black Box Warning from Varenicline's Label (FREE)
By Kristin J. Kelley Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH The FDA has agreed to remove the black box warning from the label of the smoking-cessation drug, varenicline (Chantix). The warning alerted patients about the … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - December 18, 2016 Category: Primary Care Source Type: news

FDA Drug Safety Communication: FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings
An FDA review found the side effects on mood, behavior, or thinking with the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) are lower than previously suspected. These risks still exist, but we believe the benefits of quitting smoking outweigh them. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 16, 2016 Category: Drugs & Pharmacology Source Type: news

Pfizer get OK to remove 'black box' warning on smoking cessation drug
The Food and Drug Administration has agreed to Pfizer ’s request to remove a boxed warning on its medicine prescribed to help people quit smoking. The company’s Chantix product previous carried a "black box" warning of potential neuropsychiatric events associated with the drug. Pfizer (NYSE: PFE) said the removal of the boxed warning was based on positive outcomes from what it described as the largest smoking cessation clinical trial, which involved 8,000 patients with and without histories… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - December 16, 2016 Category: American Health Authors: John George Source Type: news

Pfizer get OK to remove 'black box' warning on smoking cessation drug
The Food and Drug Administration has agreed to Pfizer ’s request to remove a boxed warning on its medicine prescribed to help people quit smoking. The company’s Chantix product previous carried a "black box" warning of potential neuropsychiatric events associated with the drug. Pfizer (NYSE: PFE) said the removal of the boxed warning was based on positive outcomes from what it described as the largest smoking cessation clinical trial, which involved 8,000 patients with and without histories… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - December 16, 2016 Category: Biotechnology Authors: John George Source Type: news

Chantix Loses Boxed Warning on Psych Effects
(MedPage Today) -- Label will still note serious neuropsychiatric risk but without the black box (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 16, 2016 Category: Psychiatry Source Type: news

Chantix, Zyban Lose Boxed Warning on Psych Effects
(MedPage Today) -- Labels will still note serious neuropsychiatric risk but without the black box (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - December 16, 2016 Category: American Health Source Type: news

FDA drops black box warning on Pfizer's anti-smoking drug
(Reuters) - U.S. health regulators on Friday allowed Pfizer Inc to remove a serious warning from the label of its smoking cessation treatment, Chantix, giving a new lease of life to the controversial drug that was approved a decade ago. (Source: Reuters: Health)
Source: Reuters: Health - December 16, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

FDA Drug Safety Communication: FDA updates label for stop smoking drug Chantix (varenicline) to include potential alcohol interaction, rare risk of seizures, and studies of side effects on mood, behavior, or thinking
[03-09-2015] The U.S. Food and Drug Administration (FDA) is warning that the prescription smoking cessation medicine Chantix (varenicline) can change the way people react to alcohol. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 15, 2016 Category: Drugs & Pharmacology Source Type: news

How to Quit Smoking
By Stacy Simon Tobacco use remains the single largest preventable cause of disease and premature death in the United States. Since the release of the Surgeon General’s Report on Smoking and Health 50 years ago, there have been 20 million deaths due to tobacco. Almost half the deaths from 12 different types of cancer combined – including lung, voice box, throat, esophagus, and bladder cancers – are attributable to cigarette smoking alone. In addition to cancer, smoking greatly increases the risk of debilitating long-term lung diseases like emphysema and chronic bronchitis. It also raises the risk for heart...
Source: American Cancer Society :: News and Features - November 16, 2016 Category: Cancer & Oncology Tags: Smoking/Tobacco Source Type: news

Varenicline and risk of self-harm: a nested case-control study - Tadrous M, Martins D, Yao Z, Mamdani MM, Juurlink DN, Gomes T, Antoniou T.
BACKGROUND: Smoking remains a serious public health concern. Pharmacotherapy for smoking cessation, including bupropion and varenicline, are proven means to increase quit rates. Post-marketing reports describing suicidal behaviours have raised concerns abo... (Source: SafetyLit)
Source: SafetyLit - November 8, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Assessment of the risk of suicide-related events induced by concomitant use of antidepressants in cases of smoking cessation treatment with varenicline and assessment of latent risk by the use of varenicline - Akimoto H, Oshima S, Negishi A, Ohara K, Ohshima S, Inoue N, Kobayashi D.
Smoking Cessation Treatment (SCT) is a policy that has to be promoted for health economics, and expectations for the success of treatments with varenicline (VAR) are large. However, the Food and Drug Administration (FDA) have issued a warning on VAR-induce... (Source: SafetyLit)
Source: SafetyLit - September 25, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

By failing to update their warnings, drug regulators are letting patients down
Varenicline could help smokers quit, but misleading warnings might stop people trying it. Should regulators like the FDA be better at communicating research?US drug regulator the Food and Drug Administration (FDA) has issued warnings about possible side effects of taking varenicline. Varenicline (marketed as Chantix in the US, and Champix in the UK) is a drug whichcan help people stop smoking. The FDA ’s warnings are out of date, do not reflect the scientific evidence, and urgently need to be updated. They may have led the public and clinicians to incorrectly believe that there was strong scientific evidence that var...
Source: Guardian Unlimited Science - September 21, 2016 Category: Science Authors: Neil Davies and Kyla Thomas Tags: Smoking Science Society Health Drugs Source Type: news

FDA Advisers Recommend Removing Chantix Boxed Warning, but Vote Was Mixed (FREE)
By Amy Orciari Herman Edited by William E. Chavey, MD, MS An FDA advisory panel voted 10-9 on Wednesday to remove the black-box warning from the label of the smoking-cessation drug varenicline (Chantix), Reuters reports. The warning alerts prescribers … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 15, 2016 Category: Primary Care Source Type: news

FDA panel votes to remove serious warning from Chantix label
Stephen FellerWASHINGTON, Sept. 15 (UPI) -- An advisory panel at the FDA voted to recommend the removal of a black box warning for psychological side effects of the drug smoking cessation drug Chantix. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 15, 2016 Category: Consumer Health News Source Type: news

FDA Panel Splits on Softening Chantix Warning
(MedPage Today) -- Panels split on removal of black box (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - September 15, 2016 Category: American Health Source Type: news

Chantix Squeaks by With Favorable FDA Safety Vote
(MedPage Today) -- Panels split on removal of black box (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - September 15, 2016 Category: Primary Care Source Type: news

Pfizer Moves Closer to FDA Removal of Suicide Warning on Chantix
Pfizer Inc. said two federal advisory panels have recommended removing the most serious warnings on its Chantix smoking cessation pill, clearing a major hurdle in the pharmaceutical giant ’s push to lessen concerns about using the medicine. (Source: WSJ.com: Health)
Source: WSJ.com: Health - September 14, 2016 Category: Pharmaceuticals Tags: PAID Source Type: news

FDA panel recommends dropping serious warning on Pfizer's Chantix
(Reuters) - A serious warning on Pfizer Inc's quit smoking drug should be removed, 10 of 19 independent panelists to the U.S. Food and Drug Administration recommended on Wednesday, after reviewing additional trial data on the controversial treatment. (Source: Reuters: Health)
Source: Reuters: Health - September 14, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

E-cigarettes 'help thousands successfully quit smoking'
Conclusion Stopping smoking remains the best thing you can possibly do for your health. Anything that can help reduce the number of people who smoke is likely to have a good impact on health. But although this study found e-cigarette use was linked to an increase in successful quit attempts, there are a number of things to be aware of: Attempting to quit with e-cigarettes alone may not be as helpful as attempting to quit using an NHS stop smoking service. Getting support and help for a quit attempt is thought to increase your chances of success fourfold. You can use NHS services and e-cigarettes together if you wish. ...
Source: NHS News Feed - September 14, 2016 Category: Consumer Health News Tags: Lifestyle/exercise Medication Heart/lungs Cancer Source Type: news

FDA Reviewers Question Chantix/Zyban Safety Study
(MedPage Today) -- Inclusion criteria and data collection criticized (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - September 13, 2016 Category: Primary Care Source Type: news

FDA Questions Validity of Smoking Cessation Drug Research FDA Questions Validity of Smoking Cessation Drug Research
The FDA has raised concerns about a postmarketing study that examined adverse neuropsychiatric events associated with smoking cessation drugs varenicline and bupropion.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 13, 2016 Category: Consumer Health News Tags: Psychiatry News Source Type: news

FDA Questions Pfizer's Chantix Trial Data
The FDA says Pfizer's study of neuropsychiatric effects of its smoking cessation drug Chantix may have presented confusing data on adverse events, potentially biasing the research. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - September 13, 2016 Category: Pharmaceuticals Source Type: news

Morning Break: FDA on Chantix; Kids and Medicine; Failure to Improve
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - September 13, 2016 Category: Psychiatry Source Type: news

FDA staff flags concerns about Pfizer's quit-smoking drug study
(Reuters) - Pfizer Inc's trial data on Chantix, a drug to help people quit smoking, failed to impress U.S. Food and Drug Administration scientists, in a blow to the company's attempts to have a serious warning removed from the drug's label. (Source: Reuters: Health)
Source: Reuters: Health - September 12, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Chantix (Varenicline) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 2, 2016 Category: Drugs & Pharmacology Source Type: news

FDA warning on drug for quitting smoking needs rethink, say researchers
Researchers from the University of Bristol have called for the USA Food and Drug Administration ’ s ‘ black box ’ warning for smoking cessation drug varenicline to be lifted. (Source: University of Bristol news)
Source: University of Bristol news - September 1, 2016 Category: Universities & Medical Training Tags: Health, Research; Faculty of Health Sciences, Faculty of Health Sciences, School of Social and Community Medicine, Institutes, Elizabeth Blackwell; Press Release Source Type: news

Quitting smoking during the second half of the menstrual cycle may help women kick the habit
Follow me on twitter @hricciot Nearly every woman will acknowledge that her menstrual cycle affects her mood and behavior. An estimated 85% of women experience premenstrual syndrome one to two weeks before her period, which may include moodiness, anxiety, irritability, or food cravings along with physical symptoms such as bloating and breast tenderness. Studies suggest that women are more likely to engage in addictive behaviors, such as cigarette smoking, in the first half of the menstrual cycle, that is the time between the start of your period and ovulation. The underlying reason is thought to be that the hormone estradi...
Source: New Harvard Health Information - July 21, 2016 Category: Consumer Health News Authors: Hope Ricciotti, MD Tags: Addiction Behavioral Health Prevention Smoking cessation Women's Health Source Type: news

Some Tobacco-Cessation Treatments Better Than Others in Women (CME/CE)
(MedPage Today) -- Chantix especially helpful for female smokers (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 14, 2016 Category: Primary Care Source Type: news

Smoking cessation success linked to sex difference
Photo by ©Shutterstock.com/Pedro Bento A meta-analysis of smoking cessation therapies, funded by the National Institute on Drug Abuse (NIDA), showed that clinicians should strongly consider varenicline as the first treatment option for women who are trying to quit smoking. Varenicline, a... (Source: NIDA News)
Source: NIDA News - July 10, 2016 Category: Addiction Tags: Tobacco, Treatment Research Source Type: news

What’s the best way to quit smoking?
Smoking cigarettes contributes to almost 1 in 5 deaths. The top three smoking-related causes of death are cardiovascular disease, lung cancer, and chronic obstructive pulmonary disease (COPD). In addition to these “top three,” smoking is also linked to a number of other cancers, an increased likelihood of getting more colds and infections, diabetes, osteoporosis and hip fractures, problems in pregnancy, difficulty with erections, stomach ulcers, gum disease, and the list goes on. Quitting smoking can add years to your life. Though the earlier the better, it’s never too late to quit. The benefits of quitti...
Source: New Harvard Health Information - July 8, 2016 Category: Consumer Health News Authors: Wynne Armand, MD Tags: Addiction Behavioral Health Lung disease Prevention Smoking cessation Source Type: news

What ’s the best way to quit smoking?
Smoking cigarettes contributes to almost 1 in 5 deaths. The top three smoking-related causes of death are cardiovascular disease, lung cancer, and chronic obstructive pulmonary disease (COPD). In addition to these “top three,” smoking is also linked to a number of other cancers, an increased likelihood of getting more colds and infections, diabetes, osteoporosis and hip fractures, problems in pregnancy, difficulty with erections, stomach ulcers, gum disease, and the list goes on. Quitting smoking can add years to your life. Though the earlier the better, it’s never too late to quit. The benefits of quitti...
Source: New Harvard Health Information - July 8, 2016 Category: Consumer Health News Authors: Wynne Armand, MD Tags: Addiction Behavioral Health Lung disease Prevention Smoking cessation Source Type: news

World No Tobacco Day 2016
31 May is World No Tobacco Day. It is organized by the World Health Organization to draw attention to the health risks associated with the use of tobacco and what can still be done to reduce tobacco consumption around the world.Here we focus on a Cochrane Review of a medical intervention - nicotine receptor partial agonists for smoking cessation - and what the available evidence tells us about its effectiveness. Cochrane Review provides more support for medication as long-term aid to quitting smokingWhen people stop smoking, they experience cravings to smoke and unpleasant mood changes. Nicotine receptor partial agonists a...
Source: Cochrane News and Events - May 31, 2016 Category: Information Technology Authors: mumoquit at cochrane.org Source Type: news

Europe lifts warning on Pfizer smoking cessation drug
LONDON (Reuters) - European regulators have lifted a warning on Pfizer's smoking cessation drug Champix - called Chantix in the United States - after a clinical study concluded it did not appear to increase the risk of neuropsychiatric side effects. (Source: Reuters: Health)
Source: Reuters: Health - May 23, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Taking prescription medication to help stop smoking is more successful long term
A new NIHR Cochrane Review has confirmed that varenicline (branded as Champix), the most commonly used prescription medication used to treat nicotine addiction, more than doubles the likelihood of stopping people smoking in the long term, compared to those who don’t use medications to help them quit. When people stop smoking they experience cravings to... (Source: NIHR Evaluation, Trials and Studies News)
Source: NIHR Evaluation, Trials and Studies News - May 12, 2016 Category: American Health Source Type: news

The FDA Should Remove Warning Label On The Smoking Cessation Drug Chantix
By removing the black box label for Chantix, the FDA will encourage the broader use of this drug and enable more and more people to quit. It is an action that needs to be taken. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 5, 2016 Category: Pharmaceuticals Authors: John LaMattina Source Type: news

The FDA Needs To Change The Label For The Smoking Cessation Drug, Chantix
By removing the black box label for Chantix, the FDA will encourage the broader use of this drug and enable more and more people to quit. It is an action that needs to be taken. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 5, 2016 Category: Pharmaceuticals Authors: John LaMattina Source Type: news

Pfizer’s EAGLES trial finds Chantix safe in smokers with psychiatric disorders
Pfizer has reported positive results from EAGLES, a multi-centre, parallel-group, post-authorisation safety study / post-marketing requirement (PASS / PMR), which was conducted in 16 countries in collaboration with GlaxoSmithKline. (Source: Drug Development Technology)
Source: Drug Development Technology - April 24, 2016 Category: Pharmaceuticals Source Type: news