Meet The Woman Who Launched A New Field Of Scientific Study

As a female chemical engineer, Frances Arnold was already a rarity. After all, only about 16 percent of chemical engineers are women. But now that she has become the first woman ever to win the prestigious Millennium Technology Prize — it was awarded in Helsinki, Finland, on May 24 — Arnold is truly one of a kind. And she knows that in addition to a big cash award (1 million euros, or about $1.3 million), the prize brings an opportunity to spotlight the gender gap in STEM (science, technology, engineering and math) careers and to be a role model for other women. "I hope that my getting this prize will highlight the fact that yes, women can do this, they can do it well, and that they can make a contribution to the world and be recognized for it," Arnold told The Huffington Post in an email. "I hope that women will see that one can have a rewarding career in science and technology." Arnold, 59, won the prize for "her discoveries that launched a field known as directed evolution," according to a statement issued by Technology Academy Finland, the organization that awards the prize. To learn more about the field, and about Arnold herself, HuffPost Science posed a series of questions to her via email. Here, lightly edited, are her answers: Did you always want to be a scientist? I did not choose to become a researcher until I was almost 30. I tried other careers, but science spoke to me more and more, especially after I started studying the...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Conclusions Moderate-to-vigorous intensity physical activity is an important predictor of cardiometabolic health in early adulthood. Strategies to prevent declines in MVPA at this life stage are required to prevent deteriorating cardiometabolic health profiles.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: EPIDEMIOLOGY Source Type: research
Conclusion These findings demonstrate that T2D and HTN attenuate tolerance to uncompensable heat stress (32°C WBGT); however, these chronic diseases do not significantly impact thermal and cardiovascular strain, or the validity of ACIGH recommendations during moderate-intensity work.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
In conclusion, awareness of the risk factors associated with IFIS, their detailed preoperative assessment and intraoperative measures and surgical intervention is crucial in addressing IFIS. Lack of awareness can turn a routine, uneventful surgery into one with significant visual morbidity.
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Exclusive: NHS launching large trial of approach that could boost number of transplants and their success rateThousands of lives could be saved globally by giving patients a 10p statin before transplants, doctors have said, as the NHS launches the world ’s largest clinical trial in organ donors.The medical breakthrough is predicted to dramatically increase the supply of organs for transplant. Currently, demand for organs vastly exceeds the number available. Every year thousands of people die waiting for a transplant, including hundreds in Britain.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Organ donation Statins Medical research NHS Health Society Science UK news Source Type: news
In conclusion, inhibiting the lysosomal oxidation of LDL in atherosclerotic lesions by antioxidants targeted at lysosomes causes the regression of atherosclerosis and improves liver and muscle characteristics in mice and might be a promising novel therapy for atherosclerosis in patients. NANOG Expression versus Cellular Senescence Are there many strategies that can reverse cellular senescence? There are certainly strategies that can lower levels of cellular senescence over time, both in cell cultures and in living an...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Acute respiratory distress syndrome is a heterogenous syndrome with many etiologies for which there are no definitive pharmacologic treatments, despite decades of research. We explore some adjunctive pharmacologic therapies, including neuromuscular blockade, corticosteroids, and inhaled pulmonary vasodilators. Additionally, we explore some investigative therapies, including Vitamin C, beta-agonists, statins, mesenchymal stromal cells, and granulocyte –macrophage colony stimulating factor. We do discuss the potential role of steroids in acute respiratory distress syndrome with severe acute respiratory syndrome coronav...
Source: Critical Care Clinics - Category: Intensive Care Authors: Source Type: research
Source: Primary Care Diabetes - Category: Primary Care Source Type: research
Source: Primary Care Diabetes - Category: Primary Care Source Type: research
Contributors : Xuezhu Li ; Dipankar Bhattacharya ; Scott L Friedman ; John C HeSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNon-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD) that underlies a growing prevalence of cirrhosis and liver cancer worldwide. Clinical studies suggest that NASH is an independent risk factor for chronic kidney disease (CKD), but models and mechanisms linking these two diseases are lacking. Here, we have characterized the renal function, histological features, and transcriptomic profile in a well-validated murin...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Our objective is to describe two genetically confirmed Oculopharyngeal Muscular Dystrophy (OPMD) patients with HMGCoARdase-antibody positive autoimmune necrotic myopathy (AINM) responsive to immunosuppressive treatment. Although clinicians have suspected muscular dystrophy patients are at increased risk of statin side-effects, to date no patients with genetically confirmed muscular dystrophy have been reported with HMGCoRdase-antibody positive AINM. Here we describe the clinical presentation, serology, muscle pathology and response to treatment in two patients with genetically confirmed OPMD who developed statin-associated AINM.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
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