GRADE Published: Liraglutide Best for Type 2 Diabetes After Metformin GRADE Published: Liraglutide Best for Type 2 Diabetes After Metformin
The US-funded GRADE trial shows liraglutide performed best overall when added to metformin, followed by insulin glargine, with sitagliptin and glimepiride trailing. But SGLT2 inhibitors were not included in study.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 21, 2022 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Pricing authority caps rates of key diabetes drugs
India's drug pricing authority has brought two key anti-diabetic drugs - Sitagliptin-Metformin combination and Linagliptin-Metformin combination - under price control. For a 2.5 mg Linagliptin-metformin tablet, the price has been fixed at 16.17, and for the same combination in 5 mg strength, the price will be 25.33 per tablet. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 25, 2022 Category: Pharmaceuticals Source Type: news

FDA: Common Diabetes Drug Januvia May Contain Traces of Carcinogen
FRIDAY, Aug. 12, 2022 -- The popular diabetes drug Januvia may contain traces of a probable carcinogen, but patients should keep using the medication because it could be dangerous to stop taking it, the U.S. Food and Drug Administration announced... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 12, 2022 Category: Pharmaceuticals Source Type: news

Common Diabetes Drug Januvia May Contain Traces of Carcinogen, FDA Says
FRIDAY, Aug. 12, 2022– The popular diabetes drug Januvia may contain traces of a probable carcinogen, but patients should keep using the medication because it could be dangerous to stop taking it, the U.S. Food and Drug Administration... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 12, 2022 Category: General Medicine Source Type: news

Samples of Popular Diabetes Drug Contain Potential Carcinogen, F.D.A. Says
Testing found nitrosamine contamination in some samples of Januvia, but regulators will allow Merck to continue selling the drug for now. (Source: NYT Health)
Source: NYT Health - August 11, 2022 Category: Consumer Health News Authors: Andrew Jacobs Tags: Drugs (Pharmaceuticals) Diabetes Regulation and Deregulation of Industry Shortages Cancer Food and Drug Administration Merck & Company Inc your-feed-healthcare Source Type: news

Januvia's Nitrosamine Contamination; COVID & Type 1 Diabetes; Vegans Who Lift
(MedPage Today) -- Some samples of the type 2 diabetes medication sitagliptin (Januvia) were found to be contaminated with nitrosamine; to avoid a shortage, the FDA is allowing Merck to temporarily distribute sitagliptin containing Nitroso-STG... (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - August 10, 2022 Category: Endocrinology Source Type: news

FDA works to avoid shortage of sitagliptin following detection of nitrosamine impurity
To avoid a shortage and help ensure patients have access to an adequate supply of the medicine, FDA will not object to the temporary distribution of sitagliptin containing NTTP above the acceptable intake limit of 37 ng per day, and up to 246.7 ng per day. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 9, 2022 Category: Drugs & Pharmacology Authors: FDA Source Type: news

EU OKs Difelikefalin for CKD-Associated Pruritus, Generic Diabetes Meds EU OKs Difelikefalin for CKD-Associated Pruritus, Generic Diabetes Meds
CHMP adopts positive opinions for a new drug for pruritis associated with chronic kidney disease, two biosimilar insulins, and a generic form of the DPP-4 inhibitor sitagliptin for type 2 diabetes.International Approvals (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - March 1, 2022 Category: Transplant Surgery Tags: Diabetes & Endocrinology News Source Type: news

EU Green Light for Finerenone for CKD, Growth Hormone for Kids EU Green Light for Finerenone for CKD, Growth Hormone for Kids
Positive opinions issued for branded somatrogon and finerenone and for generic versions of sitagliptin/metformin hydrochloride and sapropterin.International Approvals (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - December 20, 2021 Category: Transplant Surgery Tags: Diabetes & Endocrinology News Alert Source Type: news

Zydus Cadila gets US Food and Drug Administration nod for diabetes medication
On October 31, 2020, Zydus had filed a new drug application (NDA) with the USFDA seeking approval to market Sitagliptin base 25, 50 and 100 mg tablets. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 6, 2021 Category: Pharmaceuticals Source Type: news

Diabetes drug may help women who have repeated miscarriages – study
Type of stem cell deficiency is common among women who lose pregnancies, and sitagliptin may helpA common diabetes drug may be able to help women who have repeated miscarriages, researchers have found, after they identified that a certain type of stem cell deficiency is common among women who lose pregnancies.A study for the Tommy ’s National Miscarriage Research Centre in London discovered that the diabetes drugsitagliptin can boost recruitment of these cells to the lining of the uterus, called the endometrium, in women who have experienced repeated miscarriages.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - March 25, 2021 Category: Science Authors: Linda Geddes Tags: Miscarriage Medical research Stem cells Biology Science Society Source Type: news

Sitagliptin Promising Addition for Preventing Acute GVHD
Low incidence of grade II to IV acute GVHD seen in patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 7, 2021 Category: Cancer & Oncology Tags: Oncology, Pathology, Pharmacy, Journal, Source Type: news

Sitagliptin Promising Addition for Preventing Acute GVHD
THURSDAY, Jan. 7, 2020 -- For patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation, sitagliptin combined with tacrolimus and sirolimus results in a low incidence of grade II to IV acute graft-versus-host disease... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 7, 2021 Category: Pharmaceuticals Source Type: news

New studies show diabetes drug not proven to improve blood sugar control in pediatric patients
The FDA has approved labeling changes stating that Januvia (sitagliptin), Janumet (sitagliptin and metformin hydrochloride), and Janumet XR (sitagliptin and metformin hydrochloride extended-release) are not proven to improve glycemic (blood sugar) control in pediatric patients. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 4, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Sitagliptin May Cut Mortality in T2DM Patients With COVID - 19
Sitagliptin at time of hospitalization linked to reduced mortality, improved clinical outcomes (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - October 14, 2020 Category: Respiratory Medicine Tags: Endocrinology, Family Medicine, Geriatrics, Infections, Internal Medicine, Critical Care, Emergency Medicine, Pharmacy, Pulmonology, Journal, Source Type: news