He Looks At Tuberculosis Death Toll And Wonders Why You're Not Worried

Aaron Motsoaledi is tired of delivering the same spiel over and over again. No matter how many times the charismatic health minister of South Africa speaks out, people don’t seem to grasp the threat presented by tuberculosis, now the No. 1 infectious killer in the world. “People think it’s a curable disease that’s been there for ages, so what’s new? I think that’s the mentality,” Dr. Motsoaledi told The Huffington Post. As chair of the Stop TB Partnership, a group of public and private leaders hosted through the United Nations Office for Project Service, he has seen the eyes of bureaucrats around the world glaze over when he brings up TB. And yet 4,100 people die every day from the disease. His own country is one of the hardest hit. Motsoaledi has pushed to organize a comprehensive TB strategy for South Africa and its neighbors. In South Africa, they've targeted those who work in the country's mines and inhabit its prisons, two communities where TB rates are particularly high. Death by tuberculosis, he said, “happens very slowly, maybe in a corner somewhere, in an isolated hospital ward, with nobody watching, so it doesn’t evoke any emotion. Maybe that’s what’s at play around the entire world.” HuffPost spoke with Motsoaledi about the growing threat of tuberculosis ahead of World TB Day on Thursday. In your own words, what is the TB global health crisis? It’s growing, even though we’...
Source: Science - The Huffington Post - Category: Science Source Type: news

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In conclusion, the agonistic anti-TLR4 mAb induces potent CD8 T-cell-dependent antitumour immunity and an inflammatory response of lesser magnitude than does LPS. The agonistic anti-TLR4 mAb has potential as an adjuvant for use in vaccines against cancer. PMID: 31515801 [PubMed - in process]
Source: Immunology - Category: Allergy & Immunology Authors: Tags: Immunology Source Type: research
Publication date: Available online 13 September 2019Source: BiologicalsAuthor(s): Alexandra Douglas-Bardsley, Catpagavalli Asokanathan, Sharon Tierney, Jason Hockley, Kevin MarkeyAbstractPertussis toxin (PT) in its detoxified form is one of the major protective antigens in vaccines against Bordetella pertussis (whooping cough). Reference preparations of native PT are required for the quality control of pertussis vaccines. Stocks of the first WHO International Standard (IS) for PT (JNIH-5) were low and a replacement was required. One candidate material was donated by a vaccine manufacturer to NIBSC. It was formulated, lyoph...
Source: Biologicals - Category: Biology Source Type: research
Publication date: Available online 14 September 2019Source: Gene Expression PatternsAuthor(s): P. Arya, P.K. Pradhan, Anutosh Paria, R. Sharma, Dev K. Verma, Ravindra, G. Rathore, N. SoodAbstractIndia is the second largest fish producing country in the world with production of 12.6 million tonnes (mt) in 2017–18, and Indian major carps (IMCs) share bulk of this fish production. Catla, Catla catla is the fastest growing species among IMCs. However, the survival rate of catla during larval rearing is normally lower than the other IMCs i.e rohu Labeo rohita, and mrigal Cirrhinus mrigala. Continuous efforts are devoted f...
Source: Gene Expression Patterns - Category: Genetics & Stem Cells Source Type: research
A woman threw a bloody menstrual cup at lawmakers and shouted, "That's for the dead babies."
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
Former Minister of Health Oly Ilunga has been taken into custody as part of an investigation into the use of Ebola funds, according to a statement by Congo police. There have been nearly 2,000 Ebola-related deaths in the country, and roughly $200 million in aid donated in the past year.
Source: CBC | Health - Category: Consumer Health News Tags: News/World Source Type: news
Publication date: Available online 13 September 2019Source: Journal of Global Antimicrobial ResistanceAuthor(s): Vladimir Rafalskiy, Dmitry Pushkar, Sergey Yakovlev, Oleg Epstein, Mikhail Putilovskiy, Sergey Tarasov, Alexey Glazunov, Sergeiy Korenev, Ekaterina Moiseeva, Natalia GorelyshevaAbstractBackgroundUrinary tract infections (UTIs) are among the most common bacterial infections in clinical practice. The aim of the RESOURCE study was to determine the antimicrobial resistance profile of gram-negative bacteria isolated from outpatient urine samples collected across the Russian Federation.MethodsA total of 96,781 urine s...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Conclusioncarbapenem-resistance is frequent among ESBL-E in Nigeria and mainly associated with blaNDM. Genotyping suggest that these clones possibly originated from South-East Asia.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
CONCLUSIONImmunosuppression, ICU admission, antibiotics exposure including carbapenems, quinolones, glycopeptides, β‑lactams and β‑lactamase inhibitor combinations, surgery, mechanical ventilation, central venous catheterization, indwelling catheter and nasogastric catheter intubation are risk factors for CRKP infection. These conditions have to be considered in clinical practice
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Abstract Coinfection with malaria and soil-transmitted helminths (STHs) has been common among school-aged children in Tanzania. However, after a countrywide scaling up of interventions for malaria and STHs, there are limited data on the prevalence of malaria-STH coinfection and its effect on anemia in schoolchildren in Tanzania. We assessed the distribution and risk factors for malaria, STHs, and malaria-STH coinfection, and its relation to anemia among 445 primary schoolchildren in Muheza district. A semi-structured questionnaire was used to collect demographic characteristics of the children. Malaria rapid diagn...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
This study sought to quantify the effect of AMR on treatments for pediatric pneumococcal disease in Ethiopia. We developed the DREAMR (Dynamic Representation of the Economics of AMR) model that simulated children younger than 5 years who acquire pneumococcal disease (pneumonia, meningitis, and acute otitis media) and seek treatment from various health facilities in Ethiopia over a year. We examined the AMR levels of three antibiotics (penicillin, amoxicillin, and ceftriaxone), treatment failures, and attributable deaths. We used a cost-of-illness method to assess the resulting economic impact of AMR from a societal perspec...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
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