Exploring the impact of pharmacogenetics on personalized medicine: A systematic review

CONCLUSION: The studies analyzed in this review suggest a strong correlation between genetic variability and individual drug responses, supporting the use of pharmacogenetics for treatment optimization. However, for certain drugs like metformin or quetiapine, the influence of genotype on their response remains unclear. More studies with larger sample sizes, greater ethnic diversity, and consideration of non-genetic factors are needed. The lack of standardization in analysis methods and accessibility to genetic testing are significant challenges in this field. As a conclusion, pharmacogenetics shows immense potential in personalized medicine, but further research is required.PMID:38341366 | DOI:10.1016/j.farma.2023.12.004
Source: Farmacia Hospitalaria - Category: Drugs & Pharmacology Authors: Source Type: research