Novel tool for tacrolimus monitoring promising, feasible, no cost saving
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - March 1, 2020 Category: Drugs & Pharmacology Source Type: news

Tacrolimus and not cyclosporin A or sirolimus interacts synergistically in vitro with isavuconazole against Aspergillus species
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 9, 2019 Category: Respiratory Medicine Authors: MeganB Source Type: news

Immunosuppressive drug combo keeps lung transplant patients alive longer
Lung transplant patients in a recent study who took a mix of two immunosuppressive drugs, sirolimus and tacrolimus, had a median survival rate of nearly nine years -- two more than the most commonly used combination. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 29, 2019 Category: Consumer Health News Source Type: news

What is This Itchy Rash?
Discussion Atopic dermatitis (AD) has a prevalence of 3-5% in the overall U.S. population but is increasing with an estimated 10-15% lifetime risk in childhood. It is even more common in children of color with a prevalence in African-American/black children of 17% and Hispanic children of 14%. Health care utilization data also appears to support more severe disease in children of color also. Atopic dermatitis or eczema is a common dermatological skin problem which characteristically is a pruritic, papular eruption with erythema. Like most papulosquamous eruptions it often occurs in intertrigenous areas in people with alle...
Source: PediatricEducation.org - July 1, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Podcast: Immunosuppressive treatment for people with proliferative lupus nephritis
Systemic lupus erythematosus, or SLE, is an autoimmune disease that can affect any part of the body. About half the people with it develop lupus nephritis. In the June 2018 update of their Cochrane Review, David Tunnicliffe from the Centre for Kidney Research in the Children ’s Hospital at Westmead and the University of Sydney’s School of Public Health in Australia and colleagues brought together the studies that have tested a range of treatments." Lupus nephritis is a serious condition, leading to end-stage kidney disease in 15% of patients after 10 years. It mainly affects women of child-bearing age, and...
Source: Cochrane News and Events - May 30, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Update on the Use of Tacrolimus in Pediatrics Update on the Use of Tacrolimus in Pediatrics
This article provides an update for its use in children.Pediatric Pharmacotherapy (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 18, 2019 Category: Allergy & Immunology Tags: Pediatrics Journal Article Source Type: news

tacrolimus ointment (Protopic)
Title: tacrolimus ointment (Protopic)Category: MedicationsCreated: 1/21/2002 12:00:00 AMLast Editorial Review: 3/1/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - March 1, 2019 Category: Dermatology Source Type: news

Reprogramming the wonder drug rapamycin allows creation of new small-molecule drugs
(University of Helsinki) In the new study, the authors aimed to reprogram rapamycin by keeping the parts of rapamycin and tacrolimus that bind FKBP12 and changing the remaining half of the molecule in order to target completely new disease-associated proteins beyond mTOR and calcineurin. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 27, 2019 Category: International Medicine & Public Health Source Type: news

FDA Approves New Indication for Envarsus XR (tacrolimus extended-release tablets)
COPENHAGEN, Denmark, Dec. 19, 2018 /PRNewswire/ -- Veloxis Pharmaceuticals announced today that the U.S. Food& Drug Administration (FDA) approved a new indication for Envarsus XR (tacrolimus extended-release tablets) to prevent organ rejection... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - December 19, 2018 Category: Drugs & Pharmacology Source Type: news

How a Tiny Device Is Making a Big Difference for Pediatric Transplant Patients
Imagine being a pediatric kidney transplant patient and having to miss school or extracurricular activities because of clinic appointments and routine blood tests. Now imagine being offered a take-home kit that has everything you and your caregivers need to collect a blood sample at home that can be shipped to a lab. For patients like 14-year-old Josh Knapp, a kidney transplant patient in England, that choice became a reality, thanks to an initiative at Nottingham University Hospital designed to facilitate easier therapeutic drug monitoring of tacrolimus and creatinine. Made specifically for pediatric transplant patients, ...
Source: MDDI - December 14, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: IVD Source Type: news

Tacrolimus: A Role in Lupus?
(MedPage Today) -- Successful add-on treatment in small European study (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - November 6, 2018 Category: Primary Care Source Type: news

Recurrent PBC Tied to Higher Risk of Liver Graft Loss, Death (CME/CE)
(MedPage Today) -- Severe cholestasis, use of tacrolimus predicted post-graft disease recurrence (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - October 9, 2018 Category: Surgery Source Type: news

Rituximab Over Tacrolimus in Steroid-Dependent Nephrotic Syndrome? Rituximab Over Tacrolimus in Steroid-Dependent Nephrotic Syndrome?
Dr Desai reviews recent trials comparing steroid-sparing agents used to treat corticosteroid-dependent children with nephrotic syndrome.Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 8, 2018 Category: Consumer Health News Tags: Nephrology Viewpoint Source Type: news

FDA Accepts Veloxis's Supplemental New Drug Application for the De Novo Indication for ENVARSUS XR(R)
COPENHAGEN, Denmark, April 20, 2018 -- (Healthcare Sales & Marketing Network) -- Veloxis Pharmaceuticals A/S announced today that the U.S. Food & Drug Administration (FDA) has accepted for standard review the Company's supplemental New Drug Application (s... Biopharmaceuticals, FDA Veloxis Pharmaceuticals, ENVARSUS, tacrolimus, kidney transplant (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 20, 2018 Category: Pharmaceuticals Source Type: news

Drug Safety update: Oral tacrolimus products: reminder to prescribe and dispense by brand name only
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update for oral tacrolimus products. Inadvertent switching between tacrolimus products has been associated with (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - November 24, 2017 Category: Drugs & Pharmacology Source Type: news

Astagraf XL (Tacrolimus Extended-release Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 8, 2016 Category: Drugs & Pharmacology Source Type: news

Protopic (Tacrolimus) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 8, 2016 Category: Drugs & Pharmacology Source Type: news

tacrolimus (Prograf, Astagraf XL, Envarsus XR)
Title: tacrolimus (Prograf, Astagraf XL, Envarsus XR)Category: MedicationsCreated: 12/6/1998 12:00:00 AMLast Editorial Review: 9/29/2016 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - September 29, 2016 Category: Nutrition Source Type: news

Prograf (Tacrolimus) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 26, 2016 Category: Drugs & Pharmacology Source Type: news

Envarsus XR (Tacrolimus Extended-release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 6, 2016 Category: Drugs & Pharmacology Source Type: news

Immunosuppressive medication effectively treats ocular graft-versus-host-disease
A complication associated with bone marrow transplantation, graft-versus-host-disease, occurs when a transplanted immune system attacks certain parts of a host's body, and may cause severe dry eye and damage to the cornea. A clinical trial showed that topical doses of ultra low-dose tacrolimus, an immunosuppressive medication, is equally effective and showed fewer hypertensive side effects in treating ocular symptoms associated with graft-versus-host-disease than methylprednisolone, a steroid medication. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 14, 2016 Category: Science Source Type: news

Immunosuppressive medication effectively treats ocular graft-versus-host-disease
(Massachusetts Eye and Ear Infirmary) A complication associated with bone marrow transplantation, graft-versus-host-disease, occurs when a transplanted immune system attacks certain parts of a host's body, and may cause severe dry eye and damage to the cornea. A clinical trial at Massachusetts Eye and Ear showed that topical doses of ultra low-dose tacrolimus, an immunosuppressive medication, is equally effective and showed fewer hypertensive side effects in treating ocular symptoms associated with graft-versus-host-disease than methylprednisolone, a steroid medication. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 13, 2016 Category: Global & Universal Source Type: news

UCLA study yields the key to effective personalized medicine
This study demonstrated the ability to use a patient’s phenotype to personalize their treatment in an actionable manner without the need for genome profiling,” said Ho, a corresponding author of the study. “We also have shown that PPM can be extended to optimize combination therapy for a wide spectrum of diseases.” Showing that every patient’s response to medical treatment — for diseases ranging from cancer to infectious diseases, or following an organ transplant — produces a parabola-shaped graph is a landmark advance, Ho said. Among other things, the appr...
Source: UCLA Newsroom: Health Sciences - April 6, 2016 Category: Universities & Medical Training Source Type: news

Feature Review: Topical treatments for psoriasis of the scalp
 Topical treatments for psoriasis of the scalpWhat are the most effective and safest treatments?                                                                                         ...
Source: Cochrane News and Events - March 4, 2016 Category: Information Technology Authors: mumoquit at cochrane.org Source Type: news

VIDEO: What’s new on atopic dermatitis drugs and cancer concerns?
WAIKOLOA, HAWAII – Topical calcineurin inhibitors’ boxed warnings give many patients and physicians pause over cancer concerns – but a new database analysis may put some minds at ease about the drugs’ use for atopic dermatitis. “Pimecrolimus and tacrolimus are given topically, not internally –... (Source: Skin and Allergy News)
Source: Skin and Allergy News - February 17, 2016 Category: Dermatology Source Type: news

Common cause for complications after kidney transplantation identified
(University of Basel) The BK polyomavirus often causes complications after kidney transplantation. The research group of Professor Hans H. Hirsch from the Department of Biomedicine at the University of Basel has now been able to show, that the immunosuppressive drug Tacrolimus directly activates the replication of the virus and could thus be responsible for these complications. The American Journal of Transplantation has published the study. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 23, 2015 Category: Infectious Diseases Source Type: news

Scientists identify potential birth control 'pill' for men
Two drugs that help suppress the immune system in organ transplant patients may have a future as the long-sought birth control "pill" for men, new research suggests. The drugs – cyclosporine A (also known as CsA) and FK506 (also known as tacrolimus) – are given to transplant recipients to reduce... (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - October 1, 2015 Category: Science Authors: Karen Kaplan Source Type: news

Envarsus XR (Tacrolimus Extended-release Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 3, 2015 Category: Drugs & Pharmacology Source Type: news

Tacrolimus Comes Out Tops for Lupus Nephritis (CME/CE)
(MedPage Today) -- Meta-analysis compares the available immunosuppressants. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - July 25, 2015 Category: Rheumatology Source Type: news

Veloxis's Envarsus XR gets FDA approval to treat kidney transplant patients
Denmark-based Veloxis Pharmaceuticals has received approval from the US Food and Drug Administration (FDA) for its Envarsus XR (tacrolimus extended-release tablets) to treat kidney transplant patients. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - July 13, 2015 Category: Pharmaceuticals Source Type: news

Tacrolimus Market (Immunosuppressive Drug) 2020 Forecasts with 6...
2015 Market Research Report on Global Tacrolimus Industry is the new addition to pharmaceuticals market intelligence collection of DeepResearchReports.com and its industry research library focusing on...(PRWeb July 09, 2015)Read the full story at http://www.prweb.com/releases/global-tacrolimus-market/2020-forecast-analysis/prweb12836245.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - July 12, 2015 Category: Pharmaceuticals Source Type: news

Tacrolimus Won't Derail Pneumococcus Vaccine (CME/CE)
(MedPage Today) -- But there's diminished response in RA patients on it with methotrexate. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - June 14, 2015 Category: Geriatrics Source Type: news

The Emerging Role of Tacrolimus in Myasthenia GravisThe Emerging Role of Tacrolimus in Myasthenia Gravis
Is the immunosuppressive drug tacrolimus beneficial in reducing symptoms of myasthenia gravis? This review summarizes the latest evidence. Therapeutic Advances in Neurological Disorders (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 26, 2015 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Generic transplant drugs as good as brand name, experts say
Scientists have found that generic formulations of tacrolimus, a drug used post-transplant to lower the risk of organ rejection, are just as good as the name-brand version. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 3, 2015 Category: Science Source Type: news

Study: Generic transplant drugs as good as brand name
(University of Cincinnati Academic Health Center) A University of Cincinnati-led research team has found that generic formulations of tacrolimus, a drug used post-transplant to lower the risk of organ rejection, are just as good as the name-brand version. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 3, 2015 Category: Global & Universal Source Type: news

Selten Pharma, Inc. Receives Orphan Drug Designation From U.S. FDA for the Treatment of Pulmonary Arterial Hypertension
SARATOGA, Calif., March 18, 2015 -- (Healthcare Sales & Marketing Network) -- Selten Pharma, Inc., a privatively held biopharmaceutical company focused on the development and commercialization of therapies for the treatment of rare diseases, announced tod... Biopharmaceuticals, FDASelten Pharma, tacrolimus, pulmonary arterial hypertension (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 18, 2015 Category: Pharmaceuticals Source Type: news

tacrolimus, Prograf, Astagraf XL, Hectoria
Title: tacrolimus, Prograf, Astagraf XL, HectoriaCategory: MedicationsCreated: 12/6/1998 12:00:00 AMLast Editorial Review: 2/17/2015 12:00:00 AM (Source: MedicineNet Crohn's Disease General)
Source: MedicineNet Crohn's Disease General - February 17, 2015 Category: Gastroenterology Source Type: news

Tacrolimus Similar to MMF as Induction for Lupus NephritisTacrolimus Similar to MMF as Induction for Lupus Nephritis
In combination with steroids, tacrolimus (TAC) seems to have similar efficacy and safety as mycophenolate mofetil (MMF) as induction therapy for lupus nephritis, researchers reported December 30 in Annals of the Rheumatic Diseases Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 10, 2015 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Tacrolimus for Induction in Lupus Nephritis? (CME/CE)
(MedPage Today) -- Patients did just as well with tacrolimus as with mycophenolate mofetil. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 8, 2015 Category: Rheumatology Source Type: news

Prograf Aids in Myopathy-Related Lung Disease
(MedPage Today) -- Study "provides some reassurance" on use of tacrolimus. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - December 30, 2014 Category: Primary Care Source Type: news

Maintenance tacrolimus for eczema boosts quality of life
AMSTERDAM – Twice-weekly proactive maintenance therapy with 0.1% tacrolimus ointment in adults with moderate to severe atopic dermatitis resulted in dramatic improvement in self-reported quality of life in a 12-month observational study. This prospective study was designed to assess patients’ own...googletag.display('div-gpt-ad-cta'); (Source: Skin and Allergy News)
Source: Skin and Allergy News - December 15, 2014 Category: Dermatology Tags: FPN News FPN Dermatology IMN News IMN Dermatology SAN Clinical News SAN News SAN Atopic Dermatitis European Academy of Dermatology and Venereology Source Type: news

Lupus Nephritis: Multidrug Induction Ups Complete Responses Lupus Nephritis: Multidrug Induction Ups Complete Responses
A combination of tacrolimus, mycophenolate mofetil, and steroid resulted in higher remission rates than cyclophosphamide plus steroid. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 15, 2014 Category: Consumer Health News Tags: Nephrology News Source Type: news

Underused Drug Combo May Up Survival in Lung Transplant
No antibody induction therapy with sirolimus plus tacrolimus associated with maximal survival (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Pharmacy, Pulmonology, Surgery, Journal, Source Type: news

Strides Arcolab gets USFDA approval for Tacrolimus capsules
The product will be manufactured at the company's oral dosage facility at Bangalore and marketed directly by Strides in the US market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 23, 2014 Category: Pharmaceuticals Source Type: news

Topical Tacrolimus 0.03% in Vernal KeratoconjunctivitisTopical Tacrolimus 0.03% in Vernal Keratoconjunctivitis
This study compares the efficacy of this agent when used alone or combined with olopatadine. Eye & Contact Lens (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2014 Category: Consumer Health News Tags: Ophthalmology Journal Article Source Type: news

Veloxis Announces Scientific Publication of Phase II Study Demonstrating Conversion from Twice-Daily Tacrolimus to Once-Daily Envarsus® in Liver Transplant Patients
(Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - April 28, 2014 Category: Pharmaceuticals Source Type: news

Tacrolimus Eye Drops for Refractory Allergic Ocular DiseasesTacrolimus Eye Drops for Refractory Allergic Ocular Diseases
Use of tacrolimus 0.1% eye drops is associated with significant improvement of refractory allergic conjunctivitis with proliferative lesions and/or corneal involvement, according to an observational study from Japan. Reuters Health Information (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - April 22, 2014 Category: Opthalmology Tags: Ophthalmology News Source Type: news

FDA awards $2.25M grant to study immunosuppresive drug in high-risk patients
(University of Cincinnati Academic Health Center) University of Cincinnati Research Professor Rita Alloway, PharmD, has been awarded a $2.25 million grant from the U.S. Food and Drug Administration to study the safety and efficacy of the generic immunosuppressive drug tacrolimus in transplant patients. As a "cornerstone drug" in post-transplant immunosuppression, tacrolimus is used to lower the risk of organ rejection -- these studies are aimed to address public concerns regarding the use of new generic formulations in high-risk transplant recipients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 7, 2013 Category: Global & Universal Source Type: news