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Study finds epilepsy drug to be safe during pregnancy
(Wiley) New research indicates that use of the epilepsy drug lamotrigine during pregnancy does not increase the risk of birth malformations or neurodevelopmental disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 18, 2017 Category: International Medicine & Public Health Source Type: news

Acute lamotrigine overdose: a systematic review of published adult and pediatric cases - Alyahya B, Friesen M, Nauche B, Lalibert é M.
CONTEXT: Lamotrigine is a broad-spectrum anticonvulsant commonly used to treat seizure and bipolar mood disorders. Evidence from case series and retrospective studies indicate that lamotrigine overdose is usually benign. However, there are reported cases o... (Source: SafetyLit)
Source: SafetyLit - September 5, 2017 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

FDA Drug Safety Communication: Aseptic meningitis associated with use of Lamictal (lamotrigine)
[08-12-2010] The U.S. Food and Drug Administration (FDA) is informing the public that Lamictal (lamotrigine) †, a medication commonly used for seizures in children two years and older, and bipolar disorder in adults, can cause aseptic meningitis. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Reassurance on Generic Lamotrigine Bioequivalence Reassurance on Generic Lamotrigine Bioequivalence
Two disparate generic formulations of lamotrigine were found to be bioequivalent to the branded product, Lamictal, in a new FDA-sponsored study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 7, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Lamotrigine Generics Equal to Brand (CME/CE)
(MedPage Today) -- Single-dose study of generic antiepileptic drug finds minimal differences (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - June 27, 2017 Category: Consumer Health News Source Type: news

Student sues after seizure drug burned her inside and out
Khaliah Shaw was a graduate student at Georgia College and State University when she was diagnosed with bipolar disorder and prescribed the medication, Lamotrigine, in 2013. (Source: the Mail online | Health)
Source: the Mail online | Health - May 10, 2017 Category: Consumer Health News Source Type: news

Lamictal (Lamotrigine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 25, 2017 Category: Drugs & Pharmacology Source Type: news

Lamotrigine, Levetiracetam Top AEDs in Pregnancy Lamotrigine, Levetiracetam Top AEDs in Pregnancy
Researchers are tracking changes in drug use during pregnancy in women with epilepsy, as well as maternal and offspring outcomes.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - December 9, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Lamotrigine, Levetiracetam Top AEDs in Pregnancy
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - December 9, 2016 Category: Journals (General) Source Type: news

Massive lamotrigine poisoning. A case report - Grosso S, Ferranti S, Gaggiano C, Grande E, Loi B, Di Bartolo R.
We describe a child who was admitted to the emergency room because of generalized tonic-clonic status epilepticus followed by a complex neurologi... (Source: SafetyLit)
Source: SafetyLit - December 3, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

One Lot of Anticonvulsant Drug Recalled Due to Label Error (FREE)
By Kristin J. Kelley Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM One lot of the anticonvulsant drug lamotrigine has … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 30, 2016 Category: Primary Care Source Type: news

Impax Laboratories, Inc. Issues Voluntary, Nationwide Recall for One Lot of Lamotrigine Orally Disintegrating Tablet 200 mg Due to the Potential for 100 mg Blister Cards being Packaged in 200 mg Containers
Impax Laboratories, Inc. (NASDAQ: IPXL) announced today that the Company had issued a voluntary nationwide retail level recall on August 19, 2016 for one lot of Lamotrigine Orally Disintegrating Tablet (ODT) 200 mg. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 29, 2016 Category: Food Science Source Type: news

Christopher Wooll, 'burned alive' after suffering allergic reaction to lamotrigine
WARNING: GRAPHIC CONTENT: Christopher Wooll, of Warwickshire, developed Stevens Johnson Syndrome - a rare skin condition was triggered by the mood-stabilising drug lamotrigine. (Source: the Mail online | Health)
Source: the Mail online | Health - August 12, 2016 Category: Consumer Health News Source Type: news

Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother's lifestyle
This NIHR funded study found that antipsychotic use during pregnancy was not associated with worse child outcomes after poorer health and riskier lifestyles were taken into account. For pregnant women these were things like other medications, obesity, smoking, alcohol and taking illicit drugs. The study also provides further evidence against the use of valproate during pregnancy for epilepsy, bipolar disorder or schizophrenia because of the increased risk of poor outcomes for the child. The risk was double that of taking the alternatives, lamotrigine or carbamazapine during pregnancy. Mental health problems can become wors...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news

Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother's lifestyle
This NIHR funded study found that antipsychotic use during pregnancy was not associated with worse child outcomes after poorer health and riskier lifestyles were taken into account. For pregnant women these were things like other medications, obesity, smoking, alcohol and taking illicit drugs. The study also provides further evidence against the use of valproate during pregnancy for epilepsy, bipolar disorder or schizophrenia because of the increased risk of poor outcomes for the child. The risk was double that of taking the alternatives, lamotrigine or carbamazapine during pregnancy. Mental health problems can become wo...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news

No Excess Risk for Orofacial Cleft in Lamotrigine-Exposed BabiesNo Excess Risk for Orofacial Cleft in Lamotrigine-Exposed Babies
A new analysis shows no strong evidence for orofacial cleft risk among babies exposed in utero to lamotrigine, and if there is a risk, it is low, researchers conclude. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 7, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Lamotrigine May Not Cause Orofacial Birth Defects (CME/CE)
(MedPage Today) -- But large European registry case-control study suggests link to clubfoot (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 7, 2016 Category: Neurology Source Type: news

Epilepsy drug exposure does not increase newborn orofacial cleft risk
Pregnant women with epilepsy should not rule out continuing lamotrigine therapy due to concerns that exposure could increase the risk of orofacial clefts in their babies, say investigators. (Source: MedWire News)
Source: MedWire News - April 7, 2016 Category: Consumer Health News Tags: Epilepsy Source Type: news

Epilepsy Drug & Certain Birth Defects Not Linked?
Large review found no greater risk of clubfoot, cleft palate, in babies of moms-to-be who used lamotrigine (Source: WebMD Health)
Source: WebMD Health - April 6, 2016 Category: Consumer Health News Source Type: news

Study: No link between common epilepsy drug, certain birth defects
HealthDay News Despite concern from early studies, taking the epilepsy drug Lamictal during pregnancy may not raise risk for certain birth defects, a large new study finds. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 6, 2016 Category: Consumer Health News Source Type: news

Taking epilepsy drugs when pregnant may NOT raise risk of birth defects 
It was previously feared anti-seizure drug lamotrigine could raise the risk of having a baby with a cleft lip, a cleft palate or a club foot, Ulster University researchers said. (Source: the Mail online | Health)
Source: the Mail online | Health - April 6, 2016 Category: Consumer Health News Source Type: news

Study Sees No Link Between Common Epilepsy Drug, Certain Birth Defects
Large review found no greater risk of clubfoot, cleft palate, in babies of moms-to-be who used lamotrigine (Source: U.S. News - Health)
Source: U.S. News - Health - April 6, 2016 Category: Consumer Health News Source Type: news

Fetal malformation risk not increased after exposure to lamotrigine
A new analysis of registry data from European countries does not support a risk of orofacial cleft and clubfoot with exposure to lamotrigine monotherapy, in contrast to signals from previous studies... (Source: Family Practice News)
Source: Family Practice News - April 6, 2016 Category: Primary Care Source Type: news

Fetal malformation risk not increased after exposure to lamotrigine
A new analysis of registry data from European countries does not support a risk of orofacial cleft and clubfoot with exposure to lamotrigine monotherapy, in contrast to signals from previous studies... (Source: Clinical Neurology News)
Source: Clinical Neurology News - April 6, 2016 Category: Neurology Source Type: news

Study Sees No Link Between Common Epilepsy Drug, Certain Birth Defects
Large review found no greater risk of clubfoot, cleft palate, in babies of moms-to-be who used lamotrigine Source: HealthDay Related MedlinePlus Pages: Birth Defects, Epilepsy (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 6, 2016 Category: Consumer Health News Source Type: news

Study Sees No Link Between Common Epilepsy Drug, Certain Birth Defects
WEDNESDAY, April 6, 2016 -- Despite initial concern from early studies, taking the epilepsy drug lamotrigine (Lamictal) during pregnancy may not raise the risk for certain birth defects, a large new study finds. "An initial study of this drug... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 6, 2016 Category: Journals (General) Source Type: news

FDA Drug Safety Communication: Aseptic meningitis associated with use of Lamictal (lamotrigine)
[08-12-2010] The U.S. Food and Drug Administration (FDA) is informing the public that Lamictal (lamotrigine)†, a medication commonly used for seizures in children two years and older, and bipolar disorder in adults, can cause aseptic meningitis. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 25, 2016 Category: Drugs & Pharmacology Source Type: news

So Your Doctor Prescribed Lamical. Will You...
If you're taking Lamictal for bipolar disorder or for epilepsy, you may be worried that it will cause you to gain or lose weight. Learn the facts. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - March 16, 2016 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Can Lamictal (Lamotrigine) Cause or Treat...
Lamictal (lamotrigine) is prescribed for seizure disorders and bipolar disorder as a mood stabilizer, but does it treat or cause anxiety? (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - March 13, 2016 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

‘Bioequivalence’ shown for generic lamotrigine
The EQUIGEN trial shows that switching to and between generic versions of lamotrigine does not affect the plasma levels achieved by patients with epilepsy. (Source: MedWire News)
Source: MedWire News - February 17, 2016 Category: Consumer Health News Tags: Epilepsy Source Type: news

New study confirms different generics have equal efficacy when treating epilepsy
A new study tested two generic lamotrigine (prescription antiepileptic) products and found no detectable difference in clinical effects among patients in the trial. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 12, 2016 Category: Science Source Type: news

Federal Register: Recommendations for Premarket Notifications for Lamotrigine and Zonisamide Assays; Guidance for Industry and Food and Drug Administration Staff; Availability
The FDA is announcing the availability of the guidance ``Recommendations for Premarket Notifications for Lamotrigine and Zonisamide Assays.'' This guidance document discusses information to be included in premarket notifications for zonisamide or lamot... (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - February 9, 2016 Category: Medical Equipment Source Type: news

Recommendations for Premarket Notifications for Lamotrigine and Zonisamide Assays - Guidance for Industry and Food and Drug Administration Staff
This guidance document contains recommendations to manufacturers and FDA reviewers concerning information to include in premarket notifications for assays for the anti-seizure drugs, lamotrigine and zonisamide. These assays are intended to... (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - February 8, 2016 Category: Medical Equipment Source Type: news

My Doctor Stopped Lamictal Due to a Rash
Lamictal carries a strong warning, called a black box warning, about the potential for patients to develop a serious, life-threatening skin rash. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - January 24, 2016 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Adding Antiepileptic to Quetiapine Helps in Bipolar DepressionAdding Antiepileptic to Quetiapine Helps in Bipolar Depression
Adjunctive therapy with the anticonvulsant lamotrigine may improve outcomes in bipolar depression but not in the presence of folic acid. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - December 25, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

11 Things You Need to Know About Lamictal and...
Information about Lamictal - generic lamotrigine - a drug used to treat seizure disorders and as a mood stabilizer for people who have bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - March 8, 2015 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Pregnancy and Lamictal
Is Lamictal safe when pregnant? Is the generic lamotrigine safe when breast feeding? Does Lamictal cause birth defects? We try to answer these questions. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - March 1, 2015 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Excellent review of lipid rescue therapy
3.5 out of 5 stars Intravenous Lipid Emulsion in the Emergency Department: A Systematic Review of Recent Literature. Cao D et al. J Emerg Med 2014 Dec 19 [Epub ahead of print] Abstract This excellent comprehensive review of lipid rescue therapy (LRT) is vitiated only by the unavoidable fact that available clinical evidence  is so inconclusive. As the authors point out, published literature consists mostly of case reports and small case series. The vast majority of these reported cases have good outcomes and reflect positive effects from ILE, but the evidence is marred by multiple confounding variables (such ...
Source: The Poison Review - February 25, 2015 Category: Toxicology Authors: Leon Tags: Medical intralipid lipid emulsion lipid rescue therapy lipid sink Review Source Type: news

What You Need to Know About Lamictal
Lamictal - generic lamotrigine - is an anticonvulsant epilepsy medication approved for use as a mood stabilizer in the treatment of bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - January 29, 2015 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Lamictal Tastes Terrible! Here's Help for...
Taking Lamictal or lamotrigine? If so, you know how AWFUL they taste if you don't get them down fast. Here are tips for taking these and other pills. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - December 12, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Different lamotrigine generics are confirmed to be bioequivalent
Read the full story on MD Consult: Different lamotrigine generics are confirmed to be bioequivalent (Source: MD Consult: News: Top Stories)
Source: MD Consult: News: Top Stories - December 12, 2014 Category: Journals (General) Source Type: news

The Dangers Of Stevens-Johnson Syndrome
Stevens-Johnson syndrome may be caused by the drug Lamictal (lamotrigine), which is used to treat epilepsy and as a mood stabilizer for bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - December 8, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

What's the Manufacturer's Recommended Dosage...
Learn about the available strengths and manufacturer's recommended dosages for Lamictal, a mood stabilizer used in patients with bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - November 25, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Can You Get a Rash from Lamictal?
Lamictal - generic lamotrigine - prescribed for epilepsy and as a mood stabilizer for bipolar disorder - can cause serious, even life-threatening rashes. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - November 20, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Old drug may be key to new antibiotics
An anticonvulsant drug called lamotrigine is the first chemical inhibitor of the assembly of ribosomes in bacteria. he discovery is important as there is growing concern worldwide about how antibiotic resistance is making the cures for infections ineffective. The World Health Organization has declared that antibiotic resistance is a major threat to global health security. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 22, 2014 Category: Science Source Type: news

Old drug may be key to new antibiotics
(McMaster University) An anticonvulsant drug called lamotrigine is the first chemical inhibitor of the assembly of ribosomes in bacteria. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 22, 2014 Category: Infectious Diseases Source Type: news

Low-doses of fish oil may reduce seizures in patients with drug-resistant epilepsy
An estimated 3 million Americans suffer from epileptic seizures. Although drug therapies often successfully dampen the out-of-control neural firing that produces seizures, such drugs don’t work for everyone. A new study by researchers at the David Geffen School of Medicine at UCLA suggests that for such patients, improvement might come in the form of a few capsules of fish oil. The small, randomized, controlled study, published Sept. 8 in the Journal of Neurology Neurosurgery & Psychiatry (JNNP), shows that low doses of omega-3 fatty acids — the key component in common fish-oil capsules — ma...
Source: UCLA Newsroom: Health Sciences - September 9, 2014 Category: Universities & Medical Training Source Type: news

What Is Stevens-Johnson Syndrome and What...
Stevens-Johnson Syndrome is a severe inflammatory eruption of the skin and mucous membranes that may occur as a result of treatment with Lamictal (lamotrigine). More ... (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - July 18, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Does Lamictal Cause Weight Gain?
A look at the effect of Lamictal (lamotrigine) on weight. Answers the question of whether Lamictal causes weight gain. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - July 12, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Pregnant Women With Bipolar, Epilepsy Often UndertreatedPregnant Women With Bipolar, Epilepsy Often Undertreated
The pattern of lamotrigine varies widely during pregnancy and postpartum in women with bipolar disorders and may leave some vulnerable for worsening of their illness. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 23, 2014 Category: Consumer Health News Tags: Psychiatry News Source Type: news