Man's face 'peels off' after rare condition triggered by his antidepressant
WARNING: GRAPHIC CONTENT. Jonathan Laird, 38, from Greenfield, Indiana, was prescribed lamotrigine tablets in April 2016. Within a month red sores broke out inside his mouth and eyeballs. (Source: the Mail online | Health)
Source: the Mail online | Health - January 14, 2020 Category: Consumer Health News Source Type: news

Taro Pharmaceuticals U.S.A., Inc. Issues Voluntary Nationwide Recall of Lamotrigine Tablets USP, 100 mg, 100 Count Bottles
Taro Pharmaceuticals U.S.A., Inc. ( “Taro” or the “Company”) is voluntarily recalling one (1) lot of Lamotrigine 100 mg Tablets, Lot # 331771 (expiration date June 2021) in 100 count bottles, NDC 51672-4131-1 to the consumer level. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 10, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Lamotrigine in the Prevention of Migraine With Aura Lamotrigine in the Prevention of Migraine With Aura
While the antiepileptic drug lamotrigine is not recommended for the prevention of migraine in general, this review suggests that it may be promising for attacks of migraine with aura.Headache (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 4, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Lamictal XR (Lamotrigine Extended-Release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 4, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Drug Safety Communication: FDA warns of serious immune system reaction with seizure and mental health medicine lamotrigine (Lamictal)
The Food and Drug Administration (FDA) is warning that the medicine lamotrigine (Lamictal) for seizures and bipolar disorder can cause a rare but very serious reaction that excessively activates the body ’s infection-fighting immune system. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - June 19, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Rare reaction to a drug for her 'mood swings' left 14-year-old girl with a near-fatal rash
WARNING: GRAPHIC CONTENT Ashley SIlverman, 14, from Los Angeles, California, was prescribed Lamictal in November by a psychiatrist to treat her 'abnormal mood swings'. (Source: the Mail online | Health)
Source: the Mail online | Health - February 13, 2019 Category: Consumer Health News Source Type: news

Podcast: Lamotrigine versus carbamazepine monotherapy (single medication treatment) for epilepsy
Up to 70 million people worldwide have epilepsy and there are many Cochrane Reviews of ways to treat it. These include reviews that work with the original researchers to gather data on everyone who was in their studies, to perform individual participant data meta-analyses. In June 2018, Sarah Nevitt and colleagues from the University of Liverpool in the UK updated one of these reviews, comparing two commonly used drugs, lamotrigine and carbamazepine." Carbamazepine and lamotrigine are both recommended as first-line treatments for people with newly diagnosed focal onset epileptic seizures and as second-line treatments ...
Source: Cochrane News and Events - December 18, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

La FDA advierte sobre una reacci ó n grave del sistema inmunitario con el medicamento para convulsiones y enfermedades psiqui á tricas lamotrigina (Lamictal)
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 3, 2018 Category: Drugs & Pharmacology Source Type: news

La FDA advierte sobre una reacci ón grave del sistema inmunitario con el medicamento para convulsiones y enfermedades psiquiátricas lamotrigina (Lamictal)
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 3, 2018 Category: Drugs & Pharmacology Source Type: news

Potentially Fatal Immune Reactions to Lamotrigine Draw FDA Warning
(MedPage Today) -- Eight serious events including one death since drug was approved in 1994 (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 26, 2018 Category: Primary Care Source Type: news

FDA: Lamotrigine Tied to Rare, Serious Immune System Reaction FDA: Lamotrigine Tied to Rare, Serious Immune System Reaction
The FDA will add a warning about the risk for hemophagocytic lymphohistiocytosis to the prescribing information on lamotrigine drug labels.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 25, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Alert Source Type: news

FDA Drug Safety Communication: FDA warns of serious immune system reaction with seizure and mental health medicine lamotrigine (Lamictal)
The Food and Drug Administration (FDA) is warning that the medicine lamotrigine (Lamictal) for seizures and bipolar disorder can cause a rare but very serious reaction that excessively activates the body ’s infection-fighting immune system. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - April 24, 2018 Category: Drugs & Pharmacology Source Type: news

Medical News Today: What to know about Lamictal rash
Rashes are a common side effect of the epilepsy drug lamotrigine. Find out what ’s normal, warning signs to look out for, and complications. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 11, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Lamotrigine Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - November 28, 2017 Category: Drugs & Pharmacology Source Type: news

Study finds epilepsy drug to be safe during pregnancy
(Wiley) New research indicates that use of the epilepsy drug lamotrigine during pregnancy does not increase the risk of birth malformations or neurodevelopmental disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 18, 2017 Category: International Medicine & Public Health Source Type: news

Acute lamotrigine overdose: a systematic review of published adult and pediatric cases - Alyahya B, Friesen M, Nauche B, Lalibert é M.
CONTEXT: Lamotrigine is a broad-spectrum anticonvulsant commonly used to treat seizure and bipolar mood disorders. Evidence from case series and retrospective studies indicate that lamotrigine overdose is usually benign. However, there are reported cases o... (Source: SafetyLit)
Source: SafetyLit - September 5, 2017 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

FDA Drug Safety Communication: Aseptic meningitis associated with use of Lamictal (lamotrigine)
[08-12-2010] The U.S. Food and Drug Administration (FDA) is informing the public that Lamictal (lamotrigine) †, a medication commonly used for seizures in children two years and older, and bipolar disorder in adults, can cause aseptic meningitis. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Reassurance on Generic Lamotrigine Bioequivalence Reassurance on Generic Lamotrigine Bioequivalence
Two disparate generic formulations of lamotrigine were found to be bioequivalent to the branded product, Lamictal, in a new FDA-sponsored study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 7, 2017 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Lamotrigine Generics Equal to Brand (CME/CE)
(MedPage Today) -- Single-dose study of generic antiepileptic drug finds minimal differences (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - June 27, 2017 Category: Consumer Health News Source Type: news

Student sues after seizure drug burned her inside and out
Khaliah Shaw was a graduate student at Georgia College and State University when she was diagnosed with bipolar disorder and prescribed the medication, Lamotrigine, in 2013. (Source: the Mail online | Health)
Source: the Mail online | Health - May 11, 2017 Category: Consumer Health News Source Type: news

Lamictal (Lamotrigine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 25, 2017 Category: Drugs & Pharmacology Source Type: news

Lamotrigine, Levetiracetam Top AEDs in Pregnancy Lamotrigine, Levetiracetam Top AEDs in Pregnancy
Researchers are tracking changes in drug use during pregnancy in women with epilepsy, as well as maternal and offspring outcomes.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - December 9, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Lamotrigine, Levetiracetam Top AEDs in Pregnancy
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - December 9, 2016 Category: Journals (General) Source Type: news

Massive lamotrigine poisoning. A case report - Grosso S, Ferranti S, Gaggiano C, Grande E, Loi B, Di Bartolo R.
We describe a child who was admitted to the emergency room because of generalized tonic-clonic status epilepticus followed by a complex neurologi... (Source: SafetyLit)
Source: SafetyLit - December 3, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

One Lot of Anticonvulsant Drug Recalled Due to Label Error (FREE)
By Kristin J. Kelley Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM One lot of the anticonvulsant drug lamotrigine has … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 31, 2016 Category: Primary Care Source Type: news

Impax Laboratories, Inc. Issues Voluntary, Nationwide Recall for One Lot of Lamotrigine Orally Disintegrating Tablet 200 mg Due to the Potential for 100 mg Blister Cards being Packaged in 200 mg Containers
Impax Laboratories, Inc. (NASDAQ: IPXL) announced today that the Company had issued a voluntary nationwide retail level recall on August 19, 2016 for one lot of Lamotrigine Orally Disintegrating Tablet (ODT) 200 mg. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 29, 2016 Category: Food Science Source Type: news

Christopher Wooll, 'burned alive' after suffering allergic reaction to lamotrigine
WARNING: GRAPHIC CONTENT: Christopher Wooll, of Warwickshire, developed Stevens Johnson Syndrome - a rare skin condition was triggered by the mood-stabilising drug lamotrigine. (Source: the Mail online | Health)
Source: the Mail online | Health - August 12, 2016 Category: Consumer Health News Source Type: news

Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother's lifestyle
This NIHR funded study found that antipsychotic use during pregnancy was not associated with worse child outcomes after poorer health and riskier lifestyles were taken into account. For pregnant women these were things like other medications, obesity, smoking, alcohol and taking illicit drugs. The study also provides further evidence against the use of valproate during pregnancy for epilepsy, bipolar disorder or schizophrenia because of the increased risk of poor outcomes for the child. The risk was double that of taking the alternatives, lamotrigine or carbamazapine during pregnancy. Mental health problems can become wors...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news

Links between antipsychotics in pregnancy and harmful outcomes for baby may be influenced by mother's lifestyle
This NIHR funded study found that antipsychotic use during pregnancy was not associated with worse child outcomes after poorer health and riskier lifestyles were taken into account. For pregnant women these were things like other medications, obesity, smoking, alcohol and taking illicit drugs. The study also provides further evidence against the use of valproate during pregnancy for epilepsy, bipolar disorder or schizophrenia because of the increased risk of poor outcomes for the child. The risk was double that of taking the alternatives, lamotrigine or carbamazapine during pregnancy. Mental health problems can become wo...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news

No Excess Risk for Orofacial Cleft in Lamotrigine-Exposed BabiesNo Excess Risk for Orofacial Cleft in Lamotrigine-Exposed Babies
A new analysis shows no strong evidence for orofacial cleft risk among babies exposed in utero to lamotrigine, and if there is a risk, it is low, researchers conclude. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 7, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Lamotrigine May Not Cause Orofacial Birth Defects (CME/CE)
(MedPage Today) -- But large European registry case-control study suggests link to clubfoot (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - April 7, 2016 Category: Neurology Source Type: news

Epilepsy drug exposure does not increase newborn orofacial cleft risk
Pregnant women with epilepsy should not rule out continuing lamotrigine therapy due to concerns that exposure could increase the risk of orofacial clefts in their babies, say investigators. (Source: MedWire News)
Source: MedWire News - April 7, 2016 Category: Consumer Health News Tags: Epilepsy Source Type: news

Epilepsy Drug & Certain Birth Defects Not Linked?
Large review found no greater risk of clubfoot, cleft palate, in babies of moms-to-be who used lamotrigine (Source: WebMD Health)
Source: WebMD Health - April 7, 2016 Category: Consumer Health News Source Type: news

Study: No link between common epilepsy drug, certain birth defects
HealthDay News Despite concern from early studies, taking the epilepsy drug Lamictal during pregnancy may not raise risk for certain birth defects, a large new study finds. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 6, 2016 Category: Consumer Health News Source Type: news

Taking epilepsy drugs when pregnant may NOT raise risk of birth defects 
It was previously feared anti-seizure drug lamotrigine could raise the risk of having a baby with a cleft lip, a cleft palate or a club foot, Ulster University researchers said. (Source: the Mail online | Health)
Source: the Mail online | Health - April 6, 2016 Category: Consumer Health News Source Type: news

Study Sees No Link Between Common Epilepsy Drug, Certain Birth Defects
Large review found no greater risk of clubfoot, cleft palate, in babies of moms-to-be who used lamotrigine (Source: U.S. News - Health)
Source: U.S. News - Health - April 6, 2016 Category: Consumer Health News Source Type: news

Fetal malformation risk not increased after exposure to lamotrigine
A new analysis of registry data from European countries does not support a risk of orofacial cleft and clubfoot with exposure to lamotrigine monotherapy, in contrast to signals from previous studies... (Source: Family Practice News)
Source: Family Practice News - April 6, 2016 Category: Primary Care Source Type: news

Fetal malformation risk not increased after exposure to lamotrigine
A new analysis of registry data from European countries does not support a risk of orofacial cleft and clubfoot with exposure to lamotrigine monotherapy, in contrast to signals from previous studies... (Source: Clinical Neurology News)
Source: Clinical Neurology News - April 6, 2016 Category: Neurology Source Type: news

Study Sees No Link Between Common Epilepsy Drug, Certain Birth Defects
Large review found no greater risk of clubfoot, cleft palate, in babies of moms-to-be who used lamotrigine Source: HealthDay Related MedlinePlus Pages: Birth Defects, Epilepsy (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 6, 2016 Category: Consumer Health News Source Type: news

Study Sees No Link Between Common Epilepsy Drug, Certain Birth Defects
WEDNESDAY, April 6, 2016 -- Despite initial concern from early studies, taking the epilepsy drug lamotrigine (Lamictal) during pregnancy may not raise the risk for certain birth defects, a large new study finds. "An initial study of this drug... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 6, 2016 Category: Journals (General) Source Type: news

FDA Drug Safety Communication: Aseptic meningitis associated with use of Lamictal (lamotrigine)
[08-12-2010] The U.S. Food and Drug Administration (FDA) is informing the public that Lamictal (lamotrigine)†, a medication commonly used for seizures in children two years and older, and bipolar disorder in adults, can cause aseptic meningitis. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 25, 2016 Category: Drugs & Pharmacology Source Type: news

So Your Doctor Prescribed Lamical. Will You...
If you're taking Lamictal for bipolar disorder or for epilepsy, you may be worried that it will cause you to gain or lose weight. Learn the facts. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - March 16, 2016 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Can Lamictal (Lamotrigine) Cause or Treat...
Lamictal (lamotrigine) is prescribed for seizure disorders and bipolar disorder as a mood stabilizer, but does it treat or cause anxiety? (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - March 13, 2016 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

‘Bioequivalence’ shown for generic lamotrigine
The EQUIGEN trial shows that switching to and between generic versions of lamotrigine does not affect the plasma levels achieved by patients with epilepsy. (Source: MedWire News)
Source: MedWire News - February 18, 2016 Category: Consumer Health News Tags: Epilepsy Source Type: news

New study confirms different generics have equal efficacy when treating epilepsy
A new study tested two generic lamotrigine (prescription antiepileptic) products and found no detectable difference in clinical effects among patients in the trial. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 12, 2016 Category: Science Source Type: news

Federal Register: Recommendations for Premarket Notifications for Lamotrigine and Zonisamide Assays; Guidance for Industry and Food and Drug Administration Staff; Availability
The FDA is announcing the availability of the guidance ``Recommendations for Premarket Notifications for Lamotrigine and Zonisamide Assays.'' This guidance document discusses information to be included in premarket notifications for zonisamide or lamot... (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - February 9, 2016 Category: Medical Equipment Source Type: news

Recommendations for Premarket Notifications for Lamotrigine and Zonisamide Assays - Guidance for Industry and Food and Drug Administration Staff
This guidance document contains recommendations to manufacturers and FDA reviewers concerning information to include in premarket notifications for assays for the anti-seizure drugs, lamotrigine and zonisamide. These assays are intended to... (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - February 8, 2016 Category: Medical Equipment Source Type: news

My Doctor Stopped Lamictal Due to a Rash
Lamictal carries a strong warning, called a black box warning, about the potential for patients to develop a serious, life-threatening skin rash. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - January 24, 2016 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Adding Antiepileptic to Quetiapine Helps in Bipolar DepressionAdding Antiepileptic to Quetiapine Helps in Bipolar Depression
Adjunctive therapy with the anticonvulsant lamotrigine may improve outcomes in bipolar depression but not in the presence of folic acid. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - December 25, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

11 Things You Need to Know About Lamictal and...
Information about Lamictal - generic lamotrigine - a drug used to treat seizure disorders and as a mood stabilizer for people who have bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - March 8, 2015 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news