The 2024 Word of the Year: Missense

By MIKE MAGEE Not surprisingly, my nominee for “word of the year” involves AI, and specifically “the language of human biology.” As Eliezer Yudkowski, the founder of the Machine Intelligence Research Institute and coiner of the term “friendly AI” stated in Forbes: “Anything that could give rise to smarter-than-human intelligence—in the form of Artificial Intelligence, brain-computer interfaces, or neuroscience-based human intelligence enhancement – wins hands down beyond contest as doing the most to change the world. Nothing else is even in the same league.”  Perhaps the simplest way to begin is to say that “missense” is a form of misspeak or expressing oneself in words “incorrectly or imperfectly.” But in the case of “missense”, the language is not made of words, where (for example) the meaning of a sentence would be disrupted by misspelling or choosing the wrong word. With “missense”, we’re talking about a different language – the language of DNA and proteins. Specifically, the focus in on how the four base units or nucleotides that provide the skeleton of a strand of DNA communicate instructions for each of the 20 different amino acids in the form of 3 “letter” codes or “codons.” In this protein language, there are four nucleotides. Each “nucleotide” (adenine, quinine, cytosine, thymine) is a 3-part molecule which includes a nuclease, a 5-carbon sugar and a phosphate group. T...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Tech Biology Crispr DNA Mike Magee Source Type: blogs