NLRP3 Inflammasome Activation Through Heart-Brain Interaction Initiates Cardiac Inflammation and Hypertrophy During Pressure Overload

CONCLUSIONS: Cardiac inflammation and hypertrophy are regulated by heart-brain interaction. Controlling neural signals might be important for the treatment of hypertensive heart disease.PMID:36440584 | DOI:10.1161/CIRCULATIONAHA.122.060860

Source: Circulation - November 28, 2022 Category: Cardiology Authors: Yasutomi Higashikuni Wenhao Liu Genri Numata Kimie Tanaka Daiju Fukuda Yu Tanaka Yoichiro Hirata Teruhiko Imamura Eiki Takimoto Issei Komuro Masataka Sata Source Type: research