Single-cell studies offer new view of how HIV infections persist —and might be cured
This microscopic device is one of three that together separate out individual HIV-infected immune cells from blood samples and trap their genetic contents in droplets for analysis. Iain Clark and Adam Abate Curing HIV infections remains one of the most formidable challenges in biomedicine, in part because cells that hold the viral DNA in their chromosomes persist in the face of powerful drugs and immune responses. A research team has now, for the first time, isolated single cells from these stubborn viral reservoirs and characterized their gene activity, suggesting potential new cure strategie...
Source: ScienceNOW - August 3, 2022 Category: Science Source Type: news

Fourth patient seemingly cured of HIV
A man who has had HIV since the 1980s had a bone marrow transplant from a donor resistant to the virus. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 27, 2022 Category: Consumer Health News Source Type: news

Sudan: After a Successful Liver Transplant, Alia Specialist Hospital Prepares for Bone Marrow
[SudaNow] Aliaa Specialized Hospital is preparing to carry out bone marrow transplants inside after the success of the first two liver transplant operations in the country, which were performed last Wednesday, the first in which a mother donated to her daughter, followed by a second surgery last Thursday, in which a son donated liver to father. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 25, 2022 Category: African Health Source Type: news

Mayo Clinic Minute: Bone marrow donor diversity is needed
Bone marrow transplants are procedures that infuse healthy blood stem cells into your body to replace damaged or diseased bone marrow. Just like people in need of solid organ transplants, such as hearts or kidneys, people in need of a bone marrow transplant have to find a matching donor. Dr. Ernesto Ayala, a Mayo Clinic hematologist and oncologist, says bone marrow donations from people of all races and ethnicities are essential in order to help… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - July 13, 2022 Category: Databases & Libraries Source Type: news

UAB launches partnership with entity to offer life-saving service
People who need a bone marrow transplant are getting a boost locally with a new partnership between two entities. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - July 11, 2022 Category: American Health Authors: Laurel Thrailkill Source Type: news

Jon Batiste privately married Suleika Jaouad before her bone marrow transplant
Jon Batiste revealed he recently married his longtime girlfriend Suleika Jaouad. #bonemarrowtransplant #suleikajaouad #jonbatiste (Source: Reuters: Health)
Source: Reuters: Health - April 4, 2022 Category: Consumer Health News Source Type: news

Grammy winner Jon Batiste secretly married his partner Suleika Jaouad in February
The singer, 35, and the author exchanged vows the day before Suleika was admitted to hospital to undergo a bone marrow transplant after being diagnosed with leukemia for second time. #jonbatiste #suleikajaouad (Source: Reuters: Health)
Source: Reuters: Health - April 4, 2022 Category: Consumer Health News Source Type: news

Africa: First Case of HIV Cure in a Woman After Stem Cell Transplantation Reported At CROI-2022
[WHO] The International Maternal Pediatric Adolescent AIDS Clinical Trial Network (IMPAACT) P1107 reported the first case of HIV cure in a woman living with HIV submitted to a dual stem cell transplant (i.e., an umbilical cord blood transplant combined with a half-matched bone marrow transplant) for treatment of an acute myelogenous leukemia. The IMPAACT P1107 researchers presented the case details during the oral abstract session held at the 29th Conference on Retroviruses and Opportunistic Infections (CROI 202 (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - April 4, 2022 Category: Infectious Diseases Source Type: news

Woman Seemingly Cured of HIV After Umbilical Cord Transplant
Umbilical cord blood may be a good alternative to bone marrow transplants for treating HIV in patients with HIV and cancer. (Source: The Scientist)
Source: The Scientist - February 16, 2022 Category: Science Tags: News & Opinion Source Type: news

Third Person Living With HIV Has Been Cured by Transplant
Before now, only two people, both men, had been cured of HIV through bone marrow transplant. This is the first case of a woman, and someone cured using cord blood instead of bone marrow transplant. (Source: WebMD Health)
Source: WebMD Health - February 16, 2022 Category: Consumer Health News Source Type: news

A Third Person Living With HIV Has Been Cured by Transplant A Third Person Living With HIV Has Been Cured by Transplant
Before now, only two people, both men, had been cured of HIV through bone marrow transplant. This is the first case of a woman, and someone cured using cord blood instead of bone marrow transplant.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - February 15, 2022 Category: Allergy & Immunology Tags: HIV/AIDS News Source Type: news

Consumer Health: The gift of bone marrow transplantation
In this season of celebrating and gift-giving, you could have the chance to give someone the gift of a second chance at life. Each year, approximately 18,000 people in the U.S. under 74 are diagnosed with life-threatening illnesses for which a bone marrow transplant or an umbilical cord blood transplant are their best treatment options, according to the Health Resources& Services Administration. A bone marrow transplant, also called a stem cell transplant, is a… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 23, 2021 Category: Databases & Libraries Source Type: news

UCLA gene therapy gives new life to girl born with fatal immune disorder
In every visible way, Marley Gaskins is an average 12-year-old — she enjoys painting, playing online games like Roblox with her friends and taking ukulele lessons. But until recently, her life was far from normal.Marley was born with a one-in-a-million genetic disorder called leukocyte adhesion deficiency-1, or LAD-1, which cripples the immune system and results in recurring infections, coupled with slow wound healing.“She started getting what looked like ant bites on her skin when she turned 1,” said Marley’s mother, Tamara Hogue. “When she was 3, she got a really big skin abscess on her stomach that landed her ...
Source: UCLA Newsroom: Health Sciences - December 17, 2021 Category: Universities & Medical Training Source Type: news

Tanzania: New Milestone in Bone Marrow Transplant
[Daily News] MUHIMBILI National Hospital is looking to conduct bone marrow transplants to six patients every month following a successful infusion of the healthy blood-forming stem cells to five patients. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 16, 2021 Category: African Health Source Type: news

New Data from CARTITUDE-1 Study Show Continued Deep and Durable Responses of Ciltacabtagene Autoleucel (cilta-cel) in Treatment of Heavily Pretreated Patients with Multiple Myeloma
ATLANTA, Ga., December 12, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today longer-term results from the Phase 1b/2 CARTITUDE-1 study evaluating the efficacy and safety of ciltacabtagene autoleucel (cilta-cel), an investigational B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T-cell (CAR-T) therapy administered as a single infusion, in the treatment of patients with relapsed and/or refractory multiple myeloma. The data, featured as an oral presentation at the American Society of Hematology (ASH) 2021 Annual Meeting (Abstract #549) and selected as part of the Highli...
Source: Johnson and Johnson - December 12, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news