Girl, 6, bravely battles two types of rare cancer and needs bone marrow transplant
Kalea Ramos, six, from San Diego, California, was diagnosed with two forms of rare leukemia last October, leaving her in need of a bone marrow transplant - and nobody in her family is a match. (Source: the Mail online | Health)
Source: the Mail online | Health - May 28, 2018 Category: Consumer Health News Source Type: news

The Healing Edge: Five Blood Transfusions, One Bone Marrow Transplant — All Before Birth
In a bold experiment in fetal therapy, doctors in San Francisco treated a fetus with a severe, often fatal blood disorder. The child was saved, but the long-term prognosis is still uncertain. (Source: NYT Health)
Source: NYT Health - May 25, 2018 Category: Consumer Health News Authors: DENISE GRADY Tags: Transfusions Pregnancy and Childbirth Bone Marrow Genetics and Heredity Immune System University of California, San Francisco Source Type: news

New CAR T case study shows promise in acute myeloid leukemia
(H. Lee Moffitt Cancer Center& Research Institute) According to a case study from trial published online ahead of print in the journal Haematologica, a patient has remained cancer free for nine months after being treated with CYAD-01, followed by a bone marrow transplant. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 9, 2018 Category: Cancer & Oncology Source Type: news

Latest Mesothelioma Immunotherapy Combination Looks Promising
Scientists at the Vaccine and Immunotherapy Center (VIC) at Massachusetts General Hospital have uncovered a novel, two-agent immunotherapy combination that worked surprisingly well in animal models with malignant mesothelioma. The discovery has sparked new optimism for immunotherapy, which has struggled to provide consistently positive results with aggressive cancers such as mesothelioma. “This is the beginning of a new story of hope, a new combination of immunotherapy,” Dr. Mark Poznansky, director of the VIC and associate professor at Harvard Medical School, told Asbestos.com. “It worked quite well in a...
Source: Asbestos and Mesothelioma News - April 17, 2018 Category: Environmental Health Authors: Daniel King Source Type: news

Uncovering a mechanism causing chronic graft-vs-host disease after bone marrow transplant
(Medical University of South Carolina) MicroRNA-17-92 is required for the T-cell and B-cell pathogenicity that drives chronic graft-versus-host disease (cGVHD) after allogeneic bone marrow transplant (BMT), report investigators at The Medical University of South Carolina in an article prepublished online March 12, 2018 by Blood. Data from cGVHD mouse models showed that, by determining T-cell and B-cell differentiation and function, miR-17-92 is responsible for cGVHD development. Inhibiting miR-17 is a potential therapeutic strategy for preventing cGVHD in BMT patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 2, 2018 Category: Cancer & Oncology Source Type: news

Iranian man granted visa to donate bone marrow to brother in US
After almost two months, the US State Department approved a visa for an Iranian man to come to the United States in order to have bone marrow transplant surgery to help his brother, who has cancer. (Source: CNN.com - Health)
Source: CNN.com - Health - March 30, 2018 Category: Consumer Health News Source Type: news

Trump's Travel Ban Imperils U.S. Citizen With Cancer Trump's Travel Ban Imperils U.S. Citizen With Cancer
Maziar Hashemi, a naturalized U.S. citizen who lives in Massachusetts, has been told by doctors that his best hope for surviving a rare form of blood cancer is a bone marrow transplant.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - March 30, 2018 Category: Transplant Surgery Tags: Public Health & Prevention News Source Type: news

Trump travel ban hinders man's ability to have lifesaving surgery
President Donald Trump's travel ban is throwing up road blocks for a US citizen who needs a bone marrow transplant that could save his life. (Source: CNN.com - Health)
Source: CNN.com - Health - March 29, 2018 Category: Consumer Health News Source Type: news

Trump's travel ban imperils U.S. citizen with cancer
NEW YORK (Reuters) - Maziar Hashemi, a naturalized U.S. citizen who lives in Massachusetts, has been told by doctors that his best hope for surviving a rare form of blood cancer is a bone marrow transplant. (Source: Reuters: Health)
Source: Reuters: Health - March 27, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

There Is No Cure for HIV —But Scientists May Be Getting Closer
Cure isn’t a word normally used in the context of AIDS. For most of the 35 years since HIV, the virus responsible for the disease, was first identified, doctors have viewed the notion of a cure as more fantasy than fact. That’s because HIV is a virus unlike any other. It disables the very immune cells that are supposed to destroy it and also sequesters itself in the body’s cells, staging the ultimate deadly ambush whenever the immune defense’s guard comes down, months or sometimes even years later. Yet for the first time in the HIV epidemic that currently affects nearly 37 million people worldwide, ...
Source: TIME: Health - March 8, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized AIDS/HIV Source Type: news

Release of the 7th edition of the International Standards on Hematopoietic Cell Therapy
(European Society for Blood and Marrow Transplantation) The Standards are among the only sets of professional They are produced by international experts from cellular therapy programs.The Standards address every aspect of cell collection, processing and administration that impacts on the quality of products and therapeutic care.* The Standards are considered the 'gold standard' for bone marrow transplantation. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 2, 2018 Category: Biology Source Type: news

Helpful, hopeful news for bone marrow transplant patients
(Children's National Health System) Research published online by The Lancet Haematology and co-led by Kirsten M. Williams, M.D., suggests that a new imaging agent can safely show engraftment as early as days after transplant--giving a helpful and hopeful preview to patients and their doctors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 27, 2018 Category: Cancer & Oncology Source Type: news

How Cancer Immunotherapy Is Getting Even Better
Last year, the Food and Drug Administration approved two new immunotherapies to treat certain leukemias and lymphomas. Now, in a study published in the New England Journal of Medicine, researchers detail who is most likely to benefit from the treatments, called CAR T cell therapy. CAR T cell therapy trains the body’s immune system to target and destroy cancer cells in the blood; scientists take people’s own immune cells (T cells) and genetically engineer them to seek out and destroy cancer cells. The immune system can then attack cancer cells in the same way it does bacteria and viruses, and the therapy can lea...
Source: TIME: Health - February 2, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Cancer cancer cells cancer immunotherapy CAR T car t cell therapy car t gene therapy car t therapy cure for cancer healthytime leukemia leukemia treatments Source Type: news

Brave toddler meets 24 strangers who saved her life
It took a team of UCLA medical professionals and the generosity of 71 strangers to save 2-year-old Skye Savren-McCormick ’s life.The toddler from Ventura, California, required frequent blood and platelet transfusions, often on a daily basis, while undergoing  three grueling bone-marrow transplants, surgery to remove her swollen spleen and seven rounds of chemotherapy for leukemia and lymphoma. She received 77 units of blood and platelets during a 10-month stay at UCLA Mattel Children ’s Hospital.  Recently Skye ’s family got to meet and thank two dozen of the 71 strangers whose blood a...
Source: UCLA Newsroom: Health Sciences - January 19, 2018 Category: Universities & Medical Training Source Type: news

A retrospective review of fall risk factors in the bone marrow transplant inpatient service - Vela CM, Grate LM, McBride A, Devine S, Andritsos LA.
PURPOSE The purpose of this study was to compare medications and potential risk factors between patients who experienced a fall during hospitalization compared to those who did not fall while admitted to the Blood and Marrow Transplant inpatient setting at... (Source: SafetyLit)
Source: SafetyLit - January 3, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Baby survived rare blood disorder Wiskott-Aldrich syndrome after life-saving transplant
WISKOTT-ALDRICH SYNDROME is a very rare blood disorder that causes children to have a poorly functioning immune system. One baby received a stem cell bone marrow transplant to survive the condition, and can now look forward to his first Christmas without the disorder. (Source: Daily Express - Health)
Source: Daily Express - Health - December 18, 2017 Category: Consumer Health News Source Type: news

Nigeria:Lagos, Sickle Cell Foundation Partner On Bone Marrow Transplantation Programme
[Guardian] As part of efforts to improve the lives of sickle cell anaemia patients in Nigeria, the Sickle Cell Foundation Nigeria (SCFN) have received the support of the Lagos State Government towards establishment of Bone Marrow Transplantation (BMT) project. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 14, 2017 Category: African Health Source Type: news

Bone-Marrow Transplant
A slide show depicting a bone-marrow transplant. (Source: NYT Health)
Source: NYT Health - December 11, 2017 Category: Consumer Health News Source Type: news

Novel harvesting method rapidly produces superior stem cells for transplantation
(Massachusetts General Hospital) A new method of harvesting stem cells for bone marrow transplantation -- developed by a team of investigators from the Massachusetts General Hospital Cancer Center and the Harvard Stem Cell Institute -- may make the donation process more convenient and less unpleasant for donors while providing cells that are superior to those acquired by current protocols. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 7, 2017 Category: Cancer & Oncology Source Type: news

Antiviral Immunotherapy Comes of Age
T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections. (Source: The Scientist)
Source: The Scientist - December 4, 2017 Category: Science Tags: News & Opinion,News Analysis Source Type: news

GST makes ‘orphan drugs’ prices soar
These high-value ‘orphan’ drugs used in bone marrow transplant, classical Hodgkin Lymphoma, Crohn’s disease and melanoma. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 24, 2017 Category: Pharmaceuticals Source Type: news

Monoclonal antibody prevents graft-vs-host disease in bone marrow transplantation model
(Bioscribe) New research provides preclinical proof-of-concept for the ability of PRO 140, a humanized anti-CCR5 monoclonal antibody under development by CytoDyn Inc., to effectively block the development of graft-versus-host disease, a potentially lethal complication of bone marrow stem cell transplantation. CytoDyn is currently enrolling patients in a Phase 2 clinical trial with PRO 140 for the prevention of GvHD in leukemia patients undergoing BMSC transplantation. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 14, 2017 Category: Cancer & Oncology Source Type: news

How DID a transplant cure this man of HIV?
Timothy Brown, the 51-year-old American man known as the 'Berlin patient', was declared HIV-free in 2008 after two bone marrow transplants at a hospital in Berlin. (Source: the Mail online | Health)
Source: the Mail online | Health - November 10, 2017 Category: Consumer Health News Source Type: news

FDA OKs drug to block infection after marrow transplant
U.S. regulators approve new drug to prevent life-threatening infections in adults after a bone marrow transplant (Source: ABC News: Health)
Source: ABC News: Health - November 8, 2017 Category: Consumer Health News Tags: Health Source Type: news

Research suggests new way to treat inflammatory gut disease and prevent rejection of bone marrow transplants
(NYU Langone Health / NYU School of Medicine) A new study explains how a widely used drug is effective against inflammatory bowel disease and rejection of bone marrow transplants, while suggesting another way to address both health issues. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 31, 2017 Category: Biology Source Type: news

Randomized trial to determine most effective, least toxic treatment for babies with SCID
(Children's Hospital Los Angeles) Investigators plan to determine the lowest dose of chemotherapy needed for babies with severe combined immunodeficiency undergoing bone marrow transplant. The goal is to restore the immune system safely and effectively with less toxicity than the higher dose regimens currently in use. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 5, 2017 Category: International Medicine & Public Health Source Type: news

WATCH: Robin Roberts' transplant anniversary inspires Be the Match registrations
Be the Match marrow registry broke a one-day record for online registrations after "GMA" celebrated the fifth anniversary of Roberts' lifesaving bone marrow transplant. (Source: ABC News: Health)
Source: ABC News: Health - September 22, 2017 Category: Consumer Health News Tags: GMA Source Type: news

Bone marrow program for Oishei Children's receives go-ahead from state
With the new John R. Oishei Children ’s Hospital set to open in less than two months, state officials on Wednesday approved a new pediatric bone marrow transplant program to be housed at the site. The program calls for adding the program on the 12th floor in an inpatient oncology unit to be co-managed by Roswell Park Cancer Institut e. The cancer hospital’s existing bone marrow transplant program can only treat children five years and older. Part of the $1.6 billion Kaleida Health system, the… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - September 21, 2017 Category: American Health Authors: Tracey Drury Source Type: news

Robin Roberts celebrates 5th 'birthday' of bone marrow transplant
Roberts received donor cells from her sister, Sally Ann Roberts. (Source: ABC News: Health)
Source: ABC News: Health - September 20, 2017 Category: Consumer Health News Tags: Health Source Type: news

WATCH: Robin Roberts marks milestone 'birthday': 5 years since her bone marrow transplant
Plus, Dr. Richard Besser discusses the new medical advancements that have been made over the past five years, which may offer hope to those who need a marrow transplant. (Source: ABC News: Health)
Source: ABC News: Health - September 20, 2017 Category: Consumer Health News Tags: GMA Source Type: news

FDA Grants Orphan Drug Status to Cellect's ApoGraft(TM) for Acute GvHD and Chronic GvHD
ApoGraft™ aims to solve Bone Marrow Transplantation (BMT) and other transplant rejection associated diseases Cellect's CEO, Dr. Shai Yarkoni commented "We may provide the answer to a great unmet clinical need causing severe morbidity and death in t... Regenerative Medicine, FDA Cellect Biotechnology, ApoGraft, graft versus host disease, stem cell (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - September 5, 2017 Category: Pharmaceuticals Source Type: news

Gamida Cell launches severe aplastic anemia trial
Gamida Cell said today that the first patient has been transplanted in a study of its CordIn product for patients with severe aplastic anemia or hypoplastic myelodysplastic syndrome. The product is designed for patients with rare genetic diseases who have no fully-matched donors for a bone marrow transplantation. Gamida Cell said it is also evaluating its CordIn therapy for patients with sickle cell disease. Get the full story at our sister site, Drug Delivery Business News.   The post Gamida Cell launches severe aplastic anemia trial appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - August 21, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Research & Development Stem Cells Gamida Cell Source Type: news

Baby goes home after bone marrow transplant, 100-plus day hospital stay
Seven-month-old Denniya Rawls was treated for a life-threatening disorder. (Source: ABC News: Health)
Source: ABC News: Health - July 15, 2017 Category: Consumer Health News Tags: Health Source Type: news

WATCH: Baby leaves hospital after over 100-day stay
Denniya Rawls, 7 months old, underwent a lifesaving bone marrow transplant at Cleveland Clinic Children's in Cleveland, Ohio. (Source: ABC News: Health)
Source: ABC News: Health - July 14, 2017 Category: Consumer Health News Tags: Lifestyle Source Type: news

Two life-threatening conditions.One remarkable wish.
When Lucas St. Onge blew out the five candles on his birthday cake, he made just one wish. He didn’t ask for ninja turtles, a T-ball set or an Xbox — the only thing he wished was to be just like any other kid. “It was a gift I couldn’t give,” says his mom, Heather. On that same day, last May, he got his wish. “He got a liver, stomach, pancreas, intestine and spleen — the five organs he needed to help him become healthy and happy,” Heather says. Heather was 18 weeks pregnant when she and her husband, Anthony, learned they were about to face a myriad of medical challe...
Source: Thrive, Children's Hospital Boston - June 28, 2017 Category: Pediatrics Authors: Emily Williams Tags: Our Patients’ Stories bone marrow transplant Dana-Farber/Boston Children's Cancer and Blood Disorders Center Dr. Heung-Bae Kim Dr. Khashavar Vakili Dr. Rima Fawaz Intestine and Multivisceral Transplant Program Pediatric Transplant Center ( Source Type: news

David Loeb, M.D., PH.D., Named Chief of Pediatric Hematology-Oncology at the Children ’s Hospital at Montefiore and Albert Einstein College of Medicine
June 26, 2017—(BRONX, NY)—Leading pediatric oncologist and NIH-funded researcher David M. Loeb, M.D., Ph.D., has been named chief of the division of pediatric hematology, oncology, marrow and blood cell transplantation atAlbert Einstein College of Medicine and theChildren’s Hospital at Montefiore (CHAM). A noted sarcoma researcher and clinician and bone marrow transplantation specialist, Dr. Loeb will join the faculty on September 1, 2017. (Source: Einstein News)
Source: Einstein News - June 26, 2017 Category: Universities & Medical Training Source Type: news

David Loeb, M.D., Ph.D., Named Chief of Pediatric Hematology-Oncology at the Children ’s Hospital at Montefiore and Albert Einstein College of Medicine
June 26, 2017—(BRONX, NY)—Leading pediatric oncologist and NIH-funded researcher David M. Loeb, M.D., Ph.D., has been named chief of the division of pediatric hematology, oncology, marrow and blood cell transplantation atAlbert Einstein College of Medicine and theChildren’s Hospital at Montefiore (CHAM). A noted sarcoma researcher and clinician and bone marrow transplantation specialist, Dr. Loeb will join the faculty on September 1, 2017. (Source: Einstein News)
Source: Einstein News - June 26, 2017 Category: Universities & Medical Training Source Type: news

David Loeb, M.D., Ph.D., Named Chief of Pediatric Hematology-Oncology at the Children's Hospital at Montefiore and Albert Einstein College of Medicine
June 26, 2017—(BRONX, NY)—Leading pediatric oncologist and NIH-funded researcher David M. Loeb, M.D., Ph.D., has been named chief of the division of pediatric hematology, oncology, marrow and blood cell transplantation atAlbert Einstein College of Medicine and theChildren’s Hospital at Montefiore (CHAM). A noted sarcoma researcher and clinician and bone marrow transplantation specialist, Dr. Loeb will join the faculty on September 1, 2017. (Source: Einstein News)
Source: Einstein News - June 26, 2017 Category: Universities & Medical Training Source Type: news

An LAPD officer needs a bone marrow transplant. His ethnicity limits his chances of getting one
Matthew Medina, 40, suffers from an often-fatal disease. As a Filipino, his chances of finding a bone marrow donor are less than 50%. (Source: L.A. Times - Health)
Source: L.A. Times - Health - June 22, 2017 Category: Consumer Health News Authors: Soumya Karlamangla Source Type: news

Israel's Gamida Cell Raises $40 Mln for Bone Marrow Trial Israel's Gamida Cell Raises $40 Mln for Bone Marrow Trial
Israel's Gamida Cell, which is developing cellular therapies to treat cancer and rare genetic diseases, said on Monday it raised $40 million to finance the advanced trial of its product NiCord to facilitate bone marrow transplants.Reuters Health Information (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - June 20, 2017 Category: Transplant Surgery Tags: Transplantation News Source Type: news

Israel's Gamida Cell raises $40 million for bone marrow trial
TEL AVIV (Reuters) - Israel's Gamida Cell, which is developing cellular therapies to treat cancer and rare genetic diseases, said on Monday it raised $40 million to finance the advanced trial of its product NiCord to facilitate bone marrow transplants. (Source: Reuters: Health)
Source: Reuters: Health - June 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Big Slick: Three more celebrities join star-studded fundraiser
James Marsden, Samm Levine and Blake Vogt will join the star-studded lineup for Children ’s Mercy’s annual Big Slick fundraiser. The annual celebrity weekend, hosted by Kansas City comedians Rob Riggle, Paul Rudd, Jason Sudeikis, David Koechner and Eric Stonestreet will return June 23 and 24. The event has raised more than $4.5 million for Children’s Mercy since its inception sev en years ago to further pediatric cancer research, early detection and the hospital’s bone marrow transplant unit. This… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - June 9, 2017 Category: Pharmaceuticals Authors: Elise Reuter Source Type: news

Gut Bugs Signal Success of Bone Marrow Transplant (CME/CE)
(MedPage Today) -- Intestinal flora may serve as biomarkers for better survival (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - May 24, 2017 Category: Hematology Source Type: news

South Africa: Athlone Mom Starts Fund for Son's Marrow Transplant
[News24Wire] A Cape Town woman has launched a crowd-funding campaign to help her little boy get a bone marrow transplant overseas, after a local match was not found. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 20, 2017 Category: African Health Source Type: news

Engineered tissue could eliminate radiation for bone marrow transplants
Engineered bone with functional marrow. [Image courtesy Varghese lab, UC San Diego]University of California San Diego engineers have created artificial bone tissue that could eliminate the need for radiation before bone marrow transplants. Shyni Varghese, a bioengineering professor at UC San Diego Jacobs School of Engineering, led a team to develop a bone-like implant to eliminate the pre-treatment radiation that kills stem cells in a patient’s bone marrow to make room for new marrow. The newly engineered bone tissues give donor cells space room to live and grow without having to compete with pre-existing host c...
Source: Mass Device - May 15, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Research & Development Stem Cells Transplants bone marrow bone marrow disease MedTech University of California San Diego Source Type: news

New finding affecting immune reconstitution related to B cells
Researchers examined the mechanisms of B cell immune reconstitution in pediatric patients who had undergone bone marrow transplantation and discovered a disruption in the maturation of B cells -- critical to the immune system -- preventing the production of antibodies that fight infection. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 15, 2017 Category: Science Source Type: news

New finding affecting immune reconstitution related to B cells
(Children's Hospital Los Angeles) Researchers from the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles examined the mechanisms of B cell immune reconstitution in pediatric patients who had undergone bone marrow transplantation and discovered a disruption in the maturation of B cells -- critical to the immune system -- preventing the production of antibodies that fight infection. The results of the study were published in the journal Biology of Blood and Marrow Transplantation on May 12. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 15, 2017 Category: Cancer & Oncology Source Type: news

Bone marrow transplants could prevent heart diesease
Researchers from Duke University found stem cell therapy significantly improves exercise time and reduces mortality in people suffering from severe chest pain, known as angina. (Source: the Mail online | Health)
Source: the Mail online | Health - May 11, 2017 Category: Consumer Health News Source Type: news

Uganda: Bone Marrow Transplant Will Save Two Brothers
[Monitor] Lucas and Louis Masiga look playful in just about every photograph their parents proudly show off. Awesome and loving boys is how their mother Juliet Masiga describes them. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 3, 2017 Category: African Health Source Type: news