Youngest bone marrow transplant patients at higher risk of cognitive decline
(St. Jude Children's Research Hospital) Toddlers who undergo total body irradiation in preparation for bone marrow transplantation are at higher risk for a decline in IQ and may be candidates for stepped up interventions to preserve intellectual functioning, St. Jude Children's Research Hospital investigators reported. The findings appear in the current issue of the Journal of Clinical Oncology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2014 Category: Global & Universal Source Type: news

Youngest bone marrow transplant patients at higher risk of cognitive decline
St. Jude Children’s Research Hospital study identifies small group of patients at risk for intellectual decline after bone marrow transplantation; results set stage for new strategies to preserve IQ and fight cancer. (Sean Phipps, PhD) (Source: St. Jude Children's Research Hospital)
Source: St. Jude Children's Research Hospital - December 11, 2014 Category: Pediatrics Source Type: news

Predicting the storm: Can computer models improve stem cell transplantation?
(Virginia Commonwealth University) Is the human immune system similar to the weather, a seemingly random yet dynamical system that can be modeled based on past conditions to predict future states? Scientists at VCU Massey Cancer Center's award-winning Bone Marrow Transplant Program believe it is. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2014 Category: Cancer & Oncology Source Type: news

A Daughter's Plea to the Supreme Court: Let My Parents Keep Their Health Insurance
As a deeply concerned daughter, I write this plea about the upcoming Supreme Court decision in King v. Burwell, which will determine whether my parents are able to keep their badly-needed health insurance under the Affordable Care Act, otherwise known as Obamacare. This case will decide whether tax credit subsidies will remain available on federal health insurance exchanges or if these subsidies will only be available on state-run exchanges. This means that if you live in one of the 34 states that did not set up its own state exchange and you signed up through a federal exchange, you may lose the federal subsidy you receiv...
Source: Healthy Living - The Huffington Post - November 20, 2014 Category: Consumer Health News Source Type: news

UCLA researcher pioneers gene therapy cure for ‘Bubble Baby’ disease
UCLA stem cell researchers have pioneered a stem cell gene therapy cure for children born with a life-threatening condition called adenosine deaminase–deficient severe combined immunodeficiency, or ADA-deficient SCID. Often called Bubble Baby disease, the condition can be fatal within the first year of life if left untreated. The groundbreaking treatment was developed by Dr. Donald Kohn, a renowned stem cell researcher and member of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research . Kohn’s breakthrough was developed over three decades of research aimed at creating a gene ther...
Source: UCLA Newsroom: Health Sciences - November 20, 2014 Category: Universities & Medical Training Source Type: news

Donor: The German teenager who saved my life
When Sue Walters was diagnosed with leukaemia, her only chance of survival was a stem cell transplant — previously known as a bone marrow transplant. Doctors found student Nicola Gerber. (Source: the Mail online | Health)
Source: the Mail online | Health - November 18, 2014 Category: Consumer Health News Source Type: news

Mayo Clinic News Network — Headlines 11/12/14
https://www.youtube.com/watch?v=Yp_r8XTtuRQ&feature=youtu.be   Mayo Clinic News Network Headlines include: DNA test for colon cancer Sense of smell returns after brain tumor Stem cell or bone marrow transplants Journalists: The video is in the downloads. Click here for script. (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 12, 2014 Category: Databases & Libraries Source Type: news

Bone-marrow transplant teenager: 'I feel angry that my community let me down'
A teenager denied a life-saving bone marrow transplant speaks out against the shortage of ethnic minority volunteers. Antonia Hoyle reports (Source: Telegraph Health)
Source: Telegraph Health - October 20, 2014 Category: Consumer Health News Source Type: news

Drug regimen enough to control immune disease after some bone marrow transplants
A very short course of a chemotherapy drug, called cyclophosphamide, not only can prevent a life-threatening immune response in some bone marrow transplant recipients, but also can eliminate such patients' need for the usual six months of immune suppression medicines commonly prescribed to prevent severe forms of this immune response, cancer researchers report. Patients receive cyclophosphamide for two days after their bone marrow transplant, in addition to two other chemotherapy drugs given before the transplant. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 8, 2014 Category: Science Source Type: news

Two-Day Drug Regimen Enough to Control Severe Immune Disease After Some Bone Marrow Transplants - 10/7/14
Johns Hopkins and other cancer researchers report that a very short course of a chemotherapy drug, called cyclophosphamide, not only can prevent a life-threatening immune response in some bone marrow transplant recipients, but also can eliminate such patients’ need for the usual six months of immune suppression medicines commonly prescribed to prevent severe forms of this immune response. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - October 7, 2014 Category: Research Source Type: news

Drug regimen enough to control immune disease after some bone marrow transplants
(Johns Hopkins Medicine) Johns Hopkins and other cancer researchers report that a very short course of a chemotherapy drug, called cyclophosphamide, not only can prevent a life-threatening immune response in some bone marrow transplant recipients, but also can eliminate such patients' need for the usual six months of immune suppression medicines commonly prescribed to prevent severe forms of this immune response. Patients receive cyclophosphamide for two days after their bone marrow transplant, in addition to two other chemotherapy drugs given before the transplant. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 7, 2014 Category: Cancer & Oncology Source Type: news

Jeffrey Modell Foundation supports Belgian research on primary immunodeficiency
(VIB (the Flanders Institute for Biotechnology)) For the first time the Jeffrey Modell Foundation is giving a research grant to a Belgian laboratory. The team of Adrian Liston from VIB-KU Leuven will use the grant to develop a gene therapy to cure children that suffer from IPEX syndrome, a rare and fatal autoimmune disorder in which the immune system attacks the body's own tissues and organs. At the moment, the only successful therapy to treat the syndrome is a bone marrow transplantation, which is not available for all children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 9, 2014 Category: Global & Universal Source Type: news

Immune organ made from lab cells
British scientists produce a whole functional thymus capable of producing T-cellsRelated items from OnMedicaStem cells repair bowel disease Bone marrow transplant still useful in leukaemiaStem cell therapy shows promiseScientists ‘grow’ human blood vesselsScientists 'grow' working kidney (Source: OnMedica Latest News)
Source: OnMedica Latest News - August 26, 2014 Category: UK Health Source Type: news

Predicting aggressive lymphoma
A new statistical genetic analysis can detect when lymphoma will be aggressive, researchers report, thereby, allowing treatment to be initiated in time. The statistical method will be able to determine who will need a bone-marrow transplantation and who can be spared the extreme burden that this excruciating treatment entails. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 25, 2014 Category: Science Source Type: news

Immune cell discovery could help to halt cancer spread
The critical importance of highly specialized immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs has been highlighted by new research. These natural killer cells could be harnessed to hunt down and kill cancers that have spread in the body, scientists report. The team also found natural killer cells were critical to the body's rejection of donor bone marrow transplants and in the runaway immune response during toxic shock syndrome. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 14, 2014 Category: Science Source Type: news

Immune cell discovery could help to halt cancer spread
(Walter and Eliza Hall Institute) Melbourne researchers have revealed the critical importance of highly specialized immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs. These natural killer cells could be harnessed to hunt down and kill cancers that have spread in the body.The team, from the Walter and Eliza Hall Institute, also found natural killer cells were critical to the body's rejection of donor bone marrow transplants and in the runaway immune response during toxic shock syndrome. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2014 Category: Global & Universal Source Type: news

Director's Comments: Hope for Adult Severe Sickle Cell Disease
Listen to the NLM Director's Comments on "Hope for Adult Severe Sickle Cell Disease". The transcript is also available. Bone marrow transplants reversed adult severe sickle cell disease in a small but encouraging study recently published (with an accompanying editorial) in Journal of the American Medical Association... (Source: What's New on MedlinePlus)
Source: What's New on MedlinePlus - August 11, 2014 Category: Consumer Health News Source Type: news

July's top stories: Merck CMV Phase III trial, Sanofi vaccine study results
Merck enrolled the first patient in its global Phase III clinical trial of letermovir for the prevention of cytomegalovirus infection in high-risk bone marrow transplant patients, while Sanofi Pasteur reported positive results from its Phase III deng… (Source: Drug Development Technology)
Source: Drug Development Technology - August 5, 2014 Category: Pharmaceuticals Source Type: news

Most People Who Need a Marrow Transplant Will Find a DonorMost People Who Need a Marrow Transplant Will Find a Donor
Most patients who need a bone marrow transplant will find a suitable donor, but the likelihood of finding an optimal donor varies by race and ethnicity. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 25, 2014 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

New Device Costing Just £10 Detects Deadly Lung Disease
A scientist from the University of Exeter has developed a simple, cheap and highly accurate device for diagnosing a frequently fatal lung disease which attacks immune deficient individuals such as cancer patients and bone marrow transplant recipients. (Source: Medical Design Online News)
Source: Medical Design Online News - July 25, 2014 Category: Medical Equipment Source Type: news

Merck begins Phase III letermovir trial for prevention of CMV infection
US-based pharmaceutical firm Merck has enrolled the first patient in a global Phase III clinical trial of letermovir (MK-8228), an investigational antiviral agent, for prevention of cytomegalovirus (CMV) infection in high-risk bone marrow transplant … (Source: Drug Development Technology)
Source: Drug Development Technology - July 25, 2014 Category: Pharmaceuticals Source Type: news

Merck Initiates Phase 3 Study of Letermovir, an Investigational Antiviral for Prevention of Cytomegalovirus (CMV) Infection in High-Risk Bone Marrow Transplant Patients
Dateline City: WHITEHOUSE STATION, N.J. WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the first patient has been enrolled in a global Phase 3 clinical study of letermovir (MK-8228), an investigational antiviral agent. Language: English Contact: MerckMedia:Pam Eisele, 267-305-3558orRobert Consalvo, 908-423-6595orInvestor:Joseph Romanelli, 908-423-5185orJustin Holko, 908-423-5088 Ticker Slug: ...
Source: Merck.com - Research and Development News - July 24, 2014 Category: Pharmaceuticals Tags: Research and Development News Corporate News Latest News Source Type: news

Good Odds for Those Who Need Bone Marrow Donor, Study Finds
Most blood cancer patients will find an acceptable match through bone marrow registry Source: HealthDay Related MedlinePlus Pages: Bone Marrow Transplantation, Cancer, Stem Cells (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 23, 2014 Category: Consumer Health News Source Type: news

New device detects deadly lung disease
(University of Exeter) A scientist from the University of Exeter has developed a simple, cheap and highly accurate device for diagnosing a frequently fatal lung disease which attacks immune deficient individuals such as cancer patients and bone marrow transplant recipients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 23, 2014 Category: Global & Universal Source Type: news

HIV: Viral Rebound After Bone Marrow TransplantHIV: Viral Rebound After Bone Marrow Transplant
Case reports of 2 men with HIV who were in transient remission after bone marrow transplant showed that their viral loads rebounded after stopping ART. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 22, 2014 Category: Consumer Health News Tags: HIV/AIDS News Source Type: news

Aqueous two-phase systems enable multiplexing of homogeneous immunoassays
A novel test simplifies disease detection by enabling simultaneous detection of multiple proteins in blood plasma. The test can accurately and simultaneously measure multiple proteins that indicate the presence of diseases like graft-versus-host disease (bone marrow transplant rejection) in only two hours, no washing steps, and using only a minute volume of blood plasma. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 16, 2014 Category: Science Source Type: news

Bone marrow donor found for girl, 8, after #pantsonyourhead social media campaign
An eight-year-old girl is to undergo a life-saving bone marrow transplant after a social media campaign to find her a suitable donor ended in success (Source: Telegraph Health)
Source: Telegraph Health - July 14, 2014 Category: Consumer Health News Tags: Gethin Jones bone marrow donor Sam Warburton Russell Howard #pantsonyourhead campaign rare bone marrow syndrome Hollie Clark Anthony Nolan register Gareth Bale Source Type: news

Bone marrow donor found for girl, 8, after global social media campaign
An eight-year-old girl is to undergo a life-saving bone marrow transplant after a social media campaign to find her a suitable donor ended in success (Source: Telegraph Health)
Source: Telegraph Health - July 14, 2014 Category: Consumer Health News Tags: Gethin Jones bone marrow donor Sam Warburton Russell Howard #pantsonyourhead campaign rare bone marrow syndrome Hollie Clark Anthony Nolan register Gareth Bale Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include how often MDs recommend sunscreen, celiac disease and haplotype, steroids for spinal stenosis pain, and bone marrow transplantation for sickle cell disease. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - July 5, 2014 Category: Pediatrics Source Type: news

Bone marrow transplant safe, effective for adult sickle cell patients: study
NEW YORK (Reuters) - Bone marrow transplants, which have already been used to cure sickle cell disease in children, may also hold promise for adults, according to a new study. (Source: Reuters: Health)
Source: Reuters: Health - July 3, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Bone Marrow Tx Promising in Adult Sickle Cell (CME/CE)
(MedPage Today) -- Bone marrow transplantation with reduced intensity, nonmyeloablative conditioning cured many adults with severe sickle cell disease, updated results from a pilot study affirmed. (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - July 1, 2014 Category: Surgery Source Type: news

Bone Marrow Transplant Feasible for Adults With Sickle Cell Bone Marrow Transplant Feasible for Adults With Sickle Cell
Nonmyeloablative HLA-matched sibling allogeneic hematopoietic stem cell transplantation was feasible for patients aged 16 to 65 years who have severe sickle cell disease. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 1, 2014 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Toddler whose lungs collapsed during life-saving cancer treatment amazes doctors with miracle recovery
Two-year-old J’ssiah Brown, from Croydon, had to be put into an induced coma following a bone marrow transplant when his lungs collapsed and his liver failed. (Source: the Mail online | Health)
Source: the Mail online | Health - June 26, 2014 Category: Consumer Health News Source Type: news

Designer T Cells Fight Viruses After Transplants
WASHINGTON (AP) — Bone marrow transplants save thousands of lives but patients are vulnerable to severe viral infections in the months afterward, until their new immune system kicks in. Now scientists are developing protection for that risky period — injections of cells specially designed to fend off up to five different viruses at once. MoreNo Streams for You? What Supreme Court's Aereo Ruling Means NBC NewsJessica N. Turner: Moms, Put on That Swimsuit Huffington PostKnow a Debbie Downer? Stop Trying to Cheer Her Up NBC NewsViva! Pope Francis Flaunts Argentina Soccer Jersey NBC NewsUruguay eliminates Italy; Di...
Source: TIME: Top Science and Health Stories - June 25, 2014 Category: Science Authors: hannahgoldberg2014 Tags: Uncategorized medicine Research Science Source Type: news

Stars pose with pants on their head to help bone marrow patient Hollie Clark
Campaign to help eight-year-old Hollie Clark find a suitable bone marrow donor sees hundreds of people, including famous sportsmen, pose with their underwear on their head (Source: Telegraph Health)
Source: Telegraph Health - June 17, 2014 Category: Consumer Health News Tags: bone marrow donor Hollie Clarke Anthony Nolan register bone marrow transplant helphollie Source Type: news

Promising T cell therapy to protect from infections after transplant
When patients have to undergo a bone marrow transplant, the procedure weakens their immune system. Viruses that are usually kept in check in a healthy immune system may then cause potentially fatal infections. Scientists have now developed a method that could offer patients conservative protection against such infections after a transplant. The method has already been used to treat several patients successfully. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 17, 2014 Category: Science Source Type: news

Promising T cell therapy
(Technische Universitaet Muenchen) When patients have to undergo a bone marrow transplant, the procedure weakens their immune system. Viruses that are usually kept in check in a healthy immune system may then cause potentially fatal infections. Scientists at Technische Universität München, together with colleagues from Frankfurt, Würzburg and Göttingen, have now developed a method which could offer patients conservative protection against such infections after a transplant. The method has already been used to treat several patients successfully. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2014 Category: Global & Universal Source Type: news

Bringing Palliative and Hematologic Malignancy Care TogetherBringing Palliative and Hematologic Malignancy Care Together
A program to bring palliative care services to a hematologic malignancy-bone marrow transplant unit has impressive results. Medscape Nurses (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 16, 2014 Category: Consumer Health News Tags: Nursing Viewpoint Source Type: news

Sisters Bone Marrow Transplant: Mayo Clinic Radio Health Minute
In this Mayo Clinic Radio Health Minute, Imagine what it would be like to give birth to seemingly healthy twin baby girls, only to find out that both of them were born with a potentially fatal disease. To listen, click the link below. Sisters Bone Marrow Transplant (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 6, 2014 Category: Databases & Libraries Source Type: news

Clinical Advisory: Randomized, Multi-Center, Phase III Study of Allogeneic Stem Cell Transplantation Comparing Regimen Intensity in Patients with Myelodysplastic Syndrome or Acute Myeloid Leukemia (BMT CTN 0901)
Source: National Cancer Institute, National Heart, Lung, and Blood Institute - Related MedlinePlus Pages: Acute Myeloid Leukemia, Bone Marrow Transplantation, Myelodysplastic Syndromes (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 15, 2014 Category: Consumer Health News Source Type: news

Merck And AiCuris Report Phase 2 Results Of Antiviral Letermovir
AiCuris and Merck announced positive results from the Phase II trial of the investigational antiviral agent letermovir in bone marrow transplant patients. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - May 9, 2014 Category: Pharmaceuticals Source Type: news

AiCuris and Merck Announce Publication in New England Journal of Medicine of Phase 2 Clinical Trial Results of Investigational Antiviral Agent Letermovir in Bone Marrow Transplant Patients
Dateline City: WUPPERTAL, Germany & WHITEHOUSE STATION, N.J. WUPPERTAL, Germany & WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)--AiCuris and Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced the publication of results from a Phase 2 clinical trial evaluating the safety and efficacy of letermovir, an investigational, oral antiviral agent for the prevention of human cytomegalovirus (CMV) infection in patients receiving bone marrow transplant. Language: English Contact: ...
Source: Merck.com - Research and Development News - May 8, 2014 Category: Pharmaceuticals Tags: Research and Development News Corporate News Latest News Source Type: news

Odisha to set up Bone Bank, starts bone marrow transplantation
The bone transplantation works would be conducted by the department of haematology as the orthopaedics department will look after the bone bank facilities. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 7, 2014 Category: Pharmaceuticals Source Type: news

Saved by her big sister: Little girl who couldn't leave the house because 'harmless' bug could have killed her gets bone marrow transplant
Milly Smith, from New Milton, Hampshire, has a rare condition that leaves her with barely any immune system. She can now leave the house after her older sister Kacey, 8, donated her bone marrow. (Source: the Mail online | Health)
Source: the Mail online | Health - April 21, 2014 Category: Consumer Health News Source Type: news

Cancer patient, 7, is given final shot to beat the disease thanks to a bone marrow transplant from his brother, 3
Chase Atkinson, three, will undergo the operation to donate his bone marrow to Kenzie, seven, next month - who will then hopefully be able to produce the white blood cells his body desperately needs. (Source: the Mail online | Health)
Source: the Mail online | Health - April 21, 2014 Category: Consumer Health News Source Type: news