Another Patient Is Free of HIV after Receiving Virus-Resistant Cells
The risks associated with a bone marrow transplant used to treat HIV mean the procedure is unlikely to be widely used in its current form (Source: Scientific American Topic - Stem Cell Research)
Source: Scientific American Topic - Stem Cell Research - February 23, 2023 Category: Stem Cells Authors: Sara Reardon, Nature magazine Tags: Health Medicine Source Type: news
HIV patient cured after bone marrow transplant in rare case, research shows
There is “strong evidence” that the man in Düsseldorf, Germany, was cured through a high-risk procedure that offers hope for further research. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - February 21, 2023 Category: Consumer Health News Authors: Kelsey Ables Source Type: news
Brave girl of 13 beats leukaemia in world-first clinical trial
Alyssa had undergone chemotherapy and a bone marrow transplant - but her leukaemia remained. She then received genetically-edited T-cells in the first use of the therapy at Great Ormond Street. (Source: the Mail online | Health)
Source: the Mail online | Health - December 12, 2022 Category: Consumer Health News Source Type: news
Revolutionary gene therapy offers hope for untreatable cancers
UK teenager is first person in the world to receive ‘base-edited’ cells that could transform cancer medicineScientists in the UK have used a revolutionary new type of gene therapy to treat a young patient with relapsed T-cell leukaemia. The administration of the technique – a world first – has raised hopes it could soon help to tackle other childhoodcancers and serious diseases.Alyssa, from Leicester, had undergone chemotherapy and a bone marrow transplant in a bid to alleviate her leukaemia, without success. With no further treatments available, prospects for the 13-year-old were grim.Continue reading... (Source: ...
Source: Guardian Unlimited Science - December 11, 2022 Category: Science Authors: Robin McKie Observer science editor Tags: Cancer research Health Medical research Science Society UK news Source Type: news
Posterior reversible encephalopathy syndrome with hemorrhagic conversion in a patient with active polysubstance abuse: a case report and review of literature - Bender CM, Mao CE, Zangiabadi A.
Posterior reversible encephalopathy syndrome (PRES) is a neurovascular sequence noted in patients with preeclampsia/eclampsia, solid-organ/bone marrow transplantation, and malignant hypertension. The mechanism in which PRES occurs has not yet been determi... (Source: SafetyLit)
Source: SafetyLit - December 7, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Editor's notebook: Tampa Bay ’s second bone marrow transplant unit heats up the competition
The unit offers cancer patients new care options. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - November 3, 2022 Category: American Health Authors: Alexis Muellner Source Type: news
Mayo Clinic Q & amp;A podcast: Advances in bone marrow transplant and cellular therapy
Mayo Clinic performed its first bone marrow transplant in 1963 and today hundreds of people receive blood and marrow transplants every year at Mayo Clinic in Arizona, Florida and Minnesota. Recently, Mayo Clinic in Rochester, Minnesota celebrated its 10,000th blood and marrow transplant. Bone marrow transplant is used to treat blood cancers and related disorders by infusing healthy blood-forming stem cells into your body to replace unhealthy bone marrow. A bone marrow transplant is also called a stem cell… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 1, 2022 Category: Databases & Libraries Source Type: news
Kenya: First Ever Bone Marrow Transplant Conducted at Nairobi West Hospital
[Capital FM] Nairobi -- The Nairobi West hospital has successfully conducted the first ever bone marrow transplant in the country, to a female patient ailing from multiple myeloma which is a type of blood cancer. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 19, 2022 Category: African Health Source Type: news
Expert alert: Five key medical advances related to bone marrow transplantation
Mayo Clinic marks its 10,000 blood and marrow transplant in Minnesota ROCHESTER, Minn. — In the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment has become a vital cancer-fighting tool. Mayo Clinic in Rochester, Minnesota, is celebrating the 10,000th blood and marrow transplant used in the treatment of blood cancers and related disorders. Mayo Clinic performed its first bone marrow transplant in 1963. Today,… (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - October 11, 2022 Category: Hospital Management Source Type: news
BioLineRx Announces Submission of New Drug Application (NDA) to FDA for Motixafortide in Stem Cell Mobilization
Submission based on overwhelmingly positive top-line results from GENESIS Phase 3 study
Stem cell mobilization for bone marrow transplantation estimated to be> $360 million market in the U.S. (> $500 million globally), with consistent... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - September 12, 2022 Category: Drugs & Pharmacology Source Type: news
Cell therapy could improve bone marrow transplant safety
FINDINGSUCLA researchers report a step forward in the development of an “off-the-shelf” cell therapy that could reduce the severity of graft-versus-host disease in people receiving donor bone marrow transplants for the treatment of blood cancers such as leukemia and lymphoma.The method utilizes rare and powerful immune cells called invariant natural killer T, or iNKT, cells, which can reduce and delay the transplanted cells ’ attacks on healthy tissue without compromising these cells’ cancer-fighting abilities. The iNKT cells are produced from blood-forming stem cells obtained from donated umbilical cord blood and ...
Source: UCLA Newsroom: Health Sciences - September 6, 2022 Category: Universities & Medical Training Source Type: news
U.S. FDA Approves IMBRUVICA ® (ibrutinib) as First and Only BTKi Treatment for Pediatric Patients with Chronic Graft-Versus-Host Disease
August 24, 2022 (HORSHAM, PA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved IMBRUVICA® (ibrutinib) for the treatment of pediatric patients one year and older with chronic graft-versus-host disease (cGVHD) after failure of one or more lines of systemic therapy. This milestone marks the first pediatric indication for IMBRUVICA® and the introduction of a new oral suspension formulation for patients ages one to less than 12. IMBRUVICA® is now the first FDA-approved therapy for these younger patients who previously had no approv...
Source: Johnson and Johnson - August 24, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Single-cell studies offer new view of how HIV infections persist —and might be cured
This microscopic device is one of three that together separate out individual HIV-infected immune cells from blood samples and trap their genetic contents in droplets for analysis.
Iain Clark and Adam Abate
Curing HIV infections remains one of the most formidable challenges in biomedicine, in part because cells that hold the viral DNA in their chromosomes persist in the face of powerful drugs and immune responses. A research team has now, for the first time, isolated single cells from these stubborn viral reservoirs and characterized their gene activity, suggesting potential new cure strategie...
Source: ScienceNOW - August 3, 2022 Category: Science Source Type: news
Fourth patient seemingly cured of HIV
A man who has had HIV since the 1980s had a bone marrow transplant from a donor resistant to the virus. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 27, 2022 Category: Consumer Health News Source Type: news
Sudan: After a Successful Liver Transplant, Alia Specialist Hospital Prepares for Bone Marrow
[SudaNow] Aliaa Specialized Hospital is preparing to carry out bone marrow transplants inside after the success of the first two liver transplant operations in the country, which were performed last Wednesday, the first in which a mother donated to her daughter, followed by a second surgery last Thursday, in which a son donated liver to father. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 25, 2022 Category: African Health Source Type: news
