Effects of autonomic nervous system functioning and tornado exposure on long-term outcomes of aggressive children - Lochman JE, Vernberg E, Glenn A, Jarrett M, McDonald K, Powell NP, Abel M, Boxmeyer CL, Kassing F, Qu L, Romero D, Bui C.
This study examined whether pre-disaster indicators of sympathetic and parasympathetic activity moderated the relation between degree of disaster exposure from an EF-4 tornado and changes in the externalizing and internalizing behavior problems of childr... (Source: SafetyLit)
Source: SafetyLit - January 18, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

How Do I Get Rid of My Baby ’s Moro Reflex?
Title: How Do I Get Rid of My Baby ’s Moro Reflex?Category: Diseases and ConditionsCreated: 1/15/2021 12:00:00 AMLast Editorial Review: 1/15/2021 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - January 15, 2021 Category: Pediatrics Source Type: news

TalTech's neuroscientists investigate the causes of a widespread eye disease
(Estonian Research Council) Fuchs' corneal dystrophy is one of the most common eye diseases diagnosed in almost 5% of the population of Europe aged 40 years or over. It is a hereditary eye disease that causes vision impairment and typically manifests in middle age. The first symptoms of the disease - blisters on the surface of your cornea - resemble cataract at first glance. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 13, 2021 Category: International Medicine & Public Health Source Type: news

A niche for the eye
(Stowers Institute for Medical Research) What if the degenerative eye conditions that lead to glaucoma, corneal dystrophy, and cataracts could be detected and treated before vision is impaired? Recent findings from the lab of Investigator Ting Xie, PhD, at the Stowers Institute for Medical Research point to the ciliary body as a key to unlocking this possibility. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 13, 2021 Category: International Medicine & Public Health Source Type: news

New role for Antifa: Biden's 'shock troops'
(Natural News) The election of President-elect Joe Biden does not signal the end of violent anarchist group antifa, sometimes portrayed by sympathetic media as a national anti-Trump movement. (Article by Paul Bedard republished from WashingtonExaminer.com) Instead, according to a journalist who has tracked its every move, antifa is likely to feel emboldened to challenge pro-Trump... (Source: NaturalNews.com)
Source: NaturalNews.com - January 12, 2021 Category: Consumer Health News Source Type: news

Enhanced oral uptake of exosomes opens cell therapy alternative
(Cedars-Sinai Medical Center) Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows. The findings, published in the peer-reviewed Journal of Extracellular Vesicles, could help develop new oral medications for treating patients with muscular dystrophy and heart failure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 12, 2021 Category: International Medicine & Public Health Source Type: news

Science Saturday: Across time, place to find cures for inherited heart diseases
Five years ago, Jay Schneider, M.D., Ph.D., was running a lab at The University of Texas Southwestern Medical Center in Dallas. The lab focused on researching cures for the genetic muscular-wasting disorder, Duchenne muscular dystrophy. His wife, Alice Chang, M.D., had accepted an offer to work at Mayo Clinic in Rochester, Minnesota, two years before. The [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 2, 2021 Category: Databases & Libraries Source Type: news

Predicting outcome of acquired brain injury by the evolution of paroxysmal sympathetic hyperactivity signs - Lucca LF, De Tanti A, Cava F, Romoli AM, Formisano R, Scarponi F, Estraneo A, Frattini D, Tonin P, Bertolino C, Salucci P, Hakiki B, D'Ippolito M, Zampolini M, Masotta O, Premoselli S, Interlenghi M, Salvatore C, Polidori A, Cerasa A.
In this multicenter study, we provide a systematic evaluation of the clinical variability associated with paroxysmal sympathetic hyperactivity (PSH) in patients with acquired brain injury (ABI) to determine how these signs can impact outcomes. A total of... (Source: SafetyLit)
Source: SafetyLit - December 31, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Wrist and hand postures when falling and description of the upper limb falling reflex - Giddins G, Giddins H.
INTRODUCTION: Falling studies, i.e. assessing what happens when an individual falls, have been conducted in controlled environments but not in field studies for ethical reasons; this potentially limits the validity and applicability of previous studies. ... (Source: SafetyLit)
Source: SafetyLit - December 30, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Giving Back: Once a Lung Transplant Recipient, Now a Surgical Nurse
WEDNESDAY, Dec. 30, 2020 -- Nurses are known for being kind, caring and sympathetic, but Brianna Fogelman brings an uncommon empathy to her nursing job at Johns Hopkins Medicine in Baltimore. Fogelman, 27, underwent a double lung transplant last... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 30, 2020 Category: General Medicine Source Type: news

Dilation velocity is associated with Glasgow Coma Scale scores in patients with brain injury - Thakur B, Nadim H, Atem F, Stutzman SE, Olson DWM.
The objective of this study is to determine association between DV and Glasg... (Source: SafetyLit)
Source: SafetyLit - December 23, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Digging deep for differences in Duchenne muscular dystrophy
(UT Southwestern Medical Center) A UT Southwestern research team has catalogued gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchene muscular dystrophy (DMD) in humans. The findings, published online recently in PNAS, could lead to new treatments for this devastating degenerative disease and insights into factors that affect muscle development. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 21, 2020 Category: International Medicine & Public Health Source Type: news

FDA approves Roche ’s OCREVUS® (ocrelizumab) shorter 2-hour infusion for relapsing and primary progressive multiple sclerosis
Basel, 14 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved a shorter two-hour infusion time for OCREVUS ® (ocrelizumab), dosed twice-yearly for those living with relapsing or primary progressive multiple sclerosis (MS) who have not experienced any prior serious infusion reactions (IRs). The approval was based on data from the randomised, double-blind ENSEMBLE PLUS study.“More than 170,000 people with MS have been treated with OCREVUS - the only approved B-cell therapy with a twice-yearly dosing schedule - and it is the most prescribed...
Source: Roche Media News - December 14, 2020 Category: Pharmaceuticals Source Type: news

FDA approves Roche ’s OCREVUS® (ocrelizumab) shorter 2-hour infusion for relapsing and primary progressive multiple sclerosis
Basel, 14 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved a shorter two-hour infusion time for OCREVUS ® (ocrelizumab), dosed twice-yearly for those living with relapsing or primary progressive multiple sclerosis (MS) who have not experienced any prior serious infusion reactions (IRs). The approval was based on data from the randomised, double-blind ENSEMBLE PLUS study.“More than 170,000 people with MS have been treated with OCREVUS - the only approved B-cell therapy with a twice-yearly dosing schedule - and it is the most prescribed...
Source: Roche Investor Update - December 14, 2020 Category: Pharmaceuticals Source Type: news

Muscle cell secrets
(Max Delbr ü ck Center for Molecular Medicine in the Helmholtz Association) A muscle fiber consists of just one cell, but many nuclei. A team at the MDC led by Professor Carmen Birchmeier has now shown just how varied these nuclei are. The study, which has been published in Nature Communications, can help us better understand muscle diseases such as Duchenne muscular dystrophy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2020 Category: International Medicine & Public Health Source Type: news

PTC Announces Translarna(TM) Approval in Russia for the Treatment of Duchenne Muscular Dystrophy
SOUTH PLAINFIELD, N.J., Dec. 4, 2020 -- (Healthcare Sales & Marketing Network) -- PTC Therapeutics, Inc. (NASDAQ: PTCT) today announced that Translarna™ (ataluren) has been granted marketing approval in the Russian Federation for nonsense mutation Duchenn... Biopharmaceuticals, Regulatory PTC Therapeutics, Translarna, ataluren, Duchenne muscular dystrophy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 4, 2020 Category: Pharmaceuticals Source Type: news

We won ’t release Covishield for mass use until it's proven safe and immunogenic: SII
"The incident with the Chennai volunteer though highly unfortunate was in no way induced by the vaccine and SII is sympathetic with the volunteer's medical condition. However, we would like to clarify that all the requisite regulatory and ethical processes and guidelines were followed," SII said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 1, 2020 Category: Pharmaceuticals Source Type: news

The pupillary light reflex as a point-of-care test for suicide risk: preliminary results - McCall WV, Sareddy S, Youssef NA, Miller BJ, Rosenquist PB.
The pupillary light reflex (PLR) reflects physiologic arousal, and a potential point-of-care biomarker of suicide risk. We collected data from 9 healthy controls, 6 non-suicidal depressed patients, 7 with prior suicide attempts but not presently suicidal, ... (Source: SafetyLit)
Source: SafetyLit - November 28, 2020 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Hurley ’ s Picks: Is Tom Brady An Enormous Baby? Let ’ s Investigate
By Michael Hurley, CBS Boston BOSTON (CBS) — Tom Brady brings out the worst in people. It’s undeniable. Whether Tom Brady does something good or bad or in between, everyone tends to lose their minds. It’s wild. That phenomenon has cooled somewhat after Brady left the lightning-rod Patriots and joined the Tampa Bay Buccaneers, a team that very few people really care about. But it came raging back to the forefront this week when a sad Tom Brady departed the field on Monday night without shaking Jared Goff’s hand. Poor Jared Goff was left standing at midfield, looking around like a lost baby giraf...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 25, 2020 Category: Consumer Health News Authors: CBS Boston Tags: NFL Patriots Sports Syndicated Sports Hurley's Picks Jared Goff Michael Hurley NFL Picks Sports News Tampa Bay Buccaneers Thanksgiving Tom Brady Source Type: news

Evaluation of two portable pupillometers to assess clinical utility - McKay RE, Kohn MA, Schwartz ES, Larson MD.
BACKGROUND: Pupillometers have been proposed as clinical assessment tools. We compared two pupillometers to assess measurement agreement. Materials& methods: We enrolled 30 subjects and simultaneously measured the pupil diameter and light reflex ampli... (Source: SafetyLit)
Source: SafetyLit - November 20, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Morning sympathetic activity after evening binge alcohol consumption - Greenlund IM, Cunningham HA, Tikkanen AL, Bigalke JA, Smoot CA, Durocher JJ, Carter JR.
Binge alcohol consumption elicits acute and robust increases of muscle sympathetic nerve activity (MSNA), yet the impact of evening binge drinking on morning-after MSNA is unknown. The present study examined the effects of evening binge alcohol consumption... (Source: SafetyLit)
Source: SafetyLit - November 16, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Reflex Sympathetic Dystrophy (RSD, Complex Regional Pain Syndrome Type 1, CRPS)
Title: Reflex Sympathetic Dystrophy (RSD, Complex Regional Pain Syndrome Type 1, CRPS)Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 11/16/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - November 16, 2020 Category: Rheumatology Source Type: news

The clinical utility of the cervical vestibular-evoked myogenic potential (cVEMP) in university-level athletes with concussion - Felipe L, Shelton JA.
INTRODUCTION: Concussion is defined as a mild traumatic brain injury that can occur in all sport activities. Cervical vestibular-evoked myogenic potentials (cVEMPs) are accepted to demonstrate the vestibulocollic reflex. MAIN: To evaluate subclinical cervi... (Source: SafetyLit)
Source: SafetyLit - November 13, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

How Long Can You Live with Muscular Dystrophy
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 5, 2020 Category: General Medicine Source Type: news

Genetic mutation could worsen heart function in Duchenne muscular dystrophy patients
(UT Southwestern Medical Center) DALLAS - Nov. 4, 2020 - A mutation in the gene that causes cystic fibrosis may accelerate heart function decline in those with Duchenne muscular dystrophy (DMD), a new study by UT Southwestern researchers suggests. The findings, published online recently in theJournal of the American Heart Association, could help doctors develop new strategies to preserve heart function in this population, potentially extending patients' lives. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 4, 2020 Category: International Medicine & Public Health Source Type: news

The Economist failed to disclose lucrative Huawei ties, even as it defended the Chinese tech giant
(Natural News) U.K. magazine the Economist provided sympathetic coverage of Huawei – the Chinese tech giant widely seen as a national security risk – without disclosing that they had a lucrative business relationship with the firm. According to a new report by FreeBeacon, Huawei Technologies commissioned the Economist‘s business consulting division to advance its policy agendas and deflect cybersecurity... (Source: NaturalNews.com)
Source: NaturalNews.com - November 4, 2020 Category: Consumer Health News Source Type: news

Ataluren Delays Disease Milestones in Nonsense Mutation DMD Ataluren Delays Disease Milestones in Nonsense Mutation DMD
Long-term treatment with ataluren delays loss of ambulation and may delay decline in pulmonary function in patients with nonsense mutation Duchenne muscular dystrophy (nmDMD), according to study results.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 28, 2020 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

26.10.20: Bayer acquires Asklepios BioPharmaceutical to broaden innovation base in cell and gene therapy
Bayer acquires Asklepios BioPharmaceutical to broaden innovation base in cell and gene therapyAcquisition fuels Bayer's cell and gene therapy platform with potential to bring urgently needed treatments to patients across multiple disease areas with high unmet need / AskBio's industry leading AAV-based gene therapy platform already yielding commercial and clinical stage assets with potential of helping larger patient populations / Portfolio includes investigational pre-clinical and clinical stage development candidates for the treatment of neuromuscular, central nervous system, cardiovascular and metabolic diseases such as ...
Source: Bayer IR Newsfeed: Events - October 26, 2020 Category: Pharmaceuticals Source Type: news

Bayer-acquires-Asklepios-BioPharmaceutical-to-broaden-innovation-base-in-cell-and-gene-therapy
Acquisition fuels Bayer’s cell and gene therapy platform with potential to bring urgently needed treatments to patients across multiple disease areas with high unmet need / AskBio's industry leading AAV-based gene therapy platform already yielding commercial and clinical stage assets with potential of helping larger patient populations / Portfolio includes investigational pre-clinical and clinical stage development candidates for the treatment of neuromuscular, central nervous system, cardiovascular and metabolic diseases such as therapeutics for Pompe disease, Parkinson’s disease and congestive heart failure, ...
Source: Bayer Company News - October 26, 2020 Category: Pharmaceuticals Source Type: news

What Causes Joint Pain?
DiscussionMusculoskeletal problems are common problems in pediatric practice with up to 15% of acute care visits being for this problem. Joint pain is a common concern for families but the differential diagnosis is extensive and needs thoughtful consideration. History is a key to discerning the potential diagnosis but also in guiding the physical examination and laboratory examination. Family history especially for systemic diseases should be considered. On physical examination all joints should be examined include sacroiliac and temporomandibular joints. Is this arthritis or arthralgia? Distinction between inflammatory...
Source: PediatricEducation.org - October 26, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Depression affects autonomic system of the body? Yes, it does! - Singla S, Jhamb S, Singh KD, Kumar A.
BACKGROUND: Depression is a disorder of the brain, a state of low mood and aversion to activity that can affect a person's thoughts, behavior, feelings, and sense of well-being and can cause alteration in sympathetic activity of the body, thus affecting he... (Source: SafetyLit)
Source: SafetyLit - October 22, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Scientists identify compound that stimulates muscle cells in mice
UCLA researchers have identified a compound that can reproduce the effect of exercise in muscle cells in mice. Thefindings are published in the journal Cell Reports Medicine.Normally, muscles get stronger as they are used, thanks to a series of chemical signals inside muscle cells. The newly identified compound activates those signals, which suggests that compounds like it could eventually be used to treat people with limb girdle muscular dystrophy, a form of adolescent-onset muscular dystrophy.When muscles aren ’t worked regularly, they gradually atrophy. (The phenomenon is familiar to anyone who’s had a cast ...
Source: UCLA Newsroom: Health Sciences - October 21, 2020 Category: Universities & Medical Training Source Type: news

How cancer cells escape crowded tumors
(St. Anna Children's Cancer Research Institute) (Vienna, 16.10.2020) When trapped in a crowded environment, cells of the human body try to escape. Scientists now discovered that it is the cell nucleus, which triggers the " evasion reflex " . This reflex is activated once cell compression exceeds the size of the nucleus. Published in the highly renowned journal Science, this unexpected finding could help to predict treatment response and metastatic spreading of tumors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 19, 2020 Category: Cancer & Oncology Source Type: news

Impulse classification network for video head impulse test - Baydadaev S, Usmankhujaev S, Kwon J, Kim KS.
The vestibulo-ocular reflex (VOR) is a dynamic system of the human brain that helps to maintain balance and to stabilize vision during head movement. The video head impulse test (vHIT) is a clinical test that uses lightweight, high-speed video goggles to e... (Source: SafetyLit)
Source: SafetyLit - October 10, 2020 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Sarepta Therapeutics Reports Sustained Functional Improvement Two Years After Treatment with SRP-9001, its Investigational Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy
Dear Investor, Please find attached a press release from our partner Sarepta Therapeutics:https://investorrelations.sarepta.com/news-releases/news-release-details/sarepta-therapeutics-reports-sustained-functional-improvement Do not hesitate to contact us for any further questions. With best regards, (Source: Roche Investor Update)
Source: Roche Investor Update - September 28, 2020 Category: Pharmaceuticals Source Type: news

Interpreting multiple outcomes of pupillary light reflex in sport-related concussion in adolescents - Beaulieu WT, Glassman AR.
Sport-related concussions (SRCs), a form of traumatic brain injury, are a concern for athletes of all levels and parents of young athletes. Subjective measures of visual function, such as convergence, have shown promise in detecting subconcussive injury. H... (Source: SafetyLit)
Source: SafetyLit - September 26, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Utility of pupillary light reflex metrics as a physiologic biomarker for adolescent sport-related concussion - Master CL, Podolak OE, Ciuffreda KJ, Metzger KB, Joshi NR, McDonald CC, Margulies SS, Grady MF, Arbogast KB.
Importance: Concussion diagnosis remains clinical, without objective diagnostic tests available for adolescents. Known deficits in visual accommodation and autonomic function after concussion make the pupillary light reflex (PLR) a promising target as an o... (Source: SafetyLit)
Source: SafetyLit - September 26, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Pupillary Light Reflex Metrics May ID Sports Concussion in Teens
FRIDAY, Sept. 25, 2020 -- Several pupillary light reflex (PLR) metrics are increased for adolescents with concussion versus healthy controls, according to a study published online Sept. 24 in JAMA Ophthalmology. Christina L. Master, M.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 25, 2020 Category: Pharmaceuticals Source Type: news

New Duchenne muscular dystrophy drug shows benefit in Duke trial
(Duke University Medical Center) A new drug offers hope for young boys with the progressive neuromuscular disease Duchenne muscular dystrophy (DMD) by potentially offering an alternative to high-dose glucocorticoids that have significant side effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 25, 2020 Category: International Medicine & Public Health Source Type: news

Canadians should make mask-wearing a 'reflex' in daily life as COVID-19 cases rise, experts say
Experts say at this point in the pandemic, with COVID-19 cases rising, Canadians should be donning their masks more, not less. (Source: CBC | Health)
Source: CBC | Health - September 24, 2020 Category: Consumer Health News Tags: News/Canada/Toronto Source Type: news

Stomach bloating: A life-sustaining reflex could cause a bloated belly
STOMACH bloating typically occurs due to trapped air in the small intestine. One life-sustaining reflex could be the culprit behind your bloated belly - what is it? (Source: Daily Express - Health)
Source: Daily Express - Health - September 18, 2020 Category: Consumer Health News Source Type: news

A sympathetic tumor response
(Source: ScienceNOW)
Source: ScienceNOW - September 16, 2020 Category: Science Authors: Fogg, C. N. Tags: twis Source Type: news

Australia ’s field force: evolving on fast forward
The pandemic has, it will surprise no one, upended traditional ways of working for pharma ’s Australian field force. “I don't think that we will ever go back to working the way we did pre-COVID, ” says David Grolman, Medical Director at Pfizer Australia and New Zealand.”   But arguably this is less of a revolution than it might first seem. The havoc and disruption it has wreaked has merely accelerated change that was happening anyway, much of it positive, says Matthew Britland, VP of the Australian Pharmaceutical medical and scientific Professionals Association (APPA). “It’s c...
Source: EyeForPharma - September 16, 2020 Category: Pharmaceuticals Authors: Lucy Fulford Source Type: news

Scientists uncover a novel approach to treating Duchenne muscular dystrophy
(Sanford Burnham Prebys Medical Discovery Institute) Scientists at Sanford Burnham Prebys, Fondazione Santa Lucia IRCCS, and Universit à Cattolica del Sacro Cuore have shown that pharmacological (drug) correction of the content of extracellular vesicles released within dystrophic muscles can restore their ability to regenerate muscle and prevent muscle scarring. The study, published in EMBO Reports, reveals a promising new therapeutic approach for Duchenne muscular dystrophy (DMD), an incurable muscle-wasting condition, and has far-reaching implications for the field of regenerative medicine. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 15, 2020 Category: Biology Source Type: news

Drugging the undruggable: Yale finds treatment path for muscular dystrophy
Researchers have identified a possible treatment for Duchenne muscular dystrophy, a rare genetic disease for which there is currently no cure or treatment. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 11, 2020 Category: Universities & Medical Training Source Type: news

New data further reinforce Roche ’s OCREVUS (ocrelizumab) as a highly effective treatment for people with multiple sclerosis
Basel, 11 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new data that show OCREVUS® (ocrelizumab) is a highly effective treatment option for people with relapsing-remitting multiple sclerosis (RRMS) who experienced a suboptimal response to their prior disease modifying therapy (DMT). Subgroup analys is from the two-year open-label Phase IIIb CASTING study also demonstrates that patients benefit across a wide range of disease related and demographic subgroups, regardless of prior treatment background. Findings will be presented at MSVirtual2020, the 8th Joint Meeting of the Americas Committee...
Source: Roche Media News - September 11, 2020 Category: Pharmaceuticals Source Type: news

New data further reinforce Roche ’s OCREVUS (ocrelizumab) as a highly effective treatment for people with multiple sclerosis
Basel, 11 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new data that show OCREVUS® (ocrelizumab) is a highly effective treatment option for people with relapsing-remitting multiple sclerosis (RRMS) who experienced a suboptimal response to their prior disease modifying therapy (DMT). Subgroup analys is from the two-year open-label Phase IIIb CASTING study also demonstrates that patients benefit across a wide range of disease related and demographic subgroups, regardless of prior treatment background. Findings will be presented at MSVirtual2020, the 8th Joint Meeting of the Americas Committee...
Source: Roche Investor Update - September 11, 2020 Category: Pharmaceuticals Source Type: news

Drugging the undruggable: Yale finds treatment path for muscular dystrophy
(Yale University) Researchers at Yale have identified a possible treatment for Duchenne muscular dystrophy (DMD), a rare genetic disease for which there is currently no cure or treatment, by targeting an enzyme that had been considered " undruggable. " The finding appears in the Aug. 25 edition of Science Signaling. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 11, 2020 Category: International Medicine & Public Health Source Type: news

New data show Roche ’s ENSPRYNG (satralizumab) significantly reduces severity and risk of relapse in neuromyelitis optica spectrum disorder (NMOSD)
Basel, 10 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) will present new ENSPRYNG ® (satralizumab) data on reducing relapse severity in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare disease of the central nervous system. These data are being presented at MSVirtual2020, the 8th joint ACTRIMS-ECTRIMS meeting, in addition to longer-term efficacy data supporting the continued effect of ENSPRYNG on reducing the risk of NMOSD relapse, as well as its favourable benefit:risk profile.“The data for ENSPRYNG at MSVirtual2020 are promising and suggest it significantly reduces relapse severity ...
Source: Roche Media News - September 10, 2020 Category: Pharmaceuticals Source Type: news