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A potential breakthrough in the fight against muscular dystrophy, a gene therapy, is being touted by parents who were part of the trials, but the FDA isn't convinced it works. CNN medical correspondent Meg Tirrell reports. (Source: CNN.com - Health)
Source: CNN.com - Health - May 12, 2023 Category: Consumer Health News Source Type: news
When stem cells can ’t roll on a bumpy road, muscles break down
Key takeawaysStem cells travel along a collagen network to reach damaged muscle tissue and heal it.In Duchenne muscular dystrophy, stiff, scarred collagen prevents stem cells from reaching their target.A protein called sarcospan lessens this scarring and allows stem cells to do their job more successfully, pointing toward potential new treatments for the disorder.Muscles that ache after a hard workout usually don ’t hurt for long, thanks to stem cells that rush to the injured site along “collagen highways” within the muscle and repair the damaged tissue. But if the cells can’t reach their destinat...
Source: UCLA Newsroom: Health Sciences - May 12, 2023 Category: Universities & Medical Training Source Type: news
Sarepta's Duchenne Gene Therapy Does Not Have 'Unambiguous Evidence,' FDA Staff Says
(MedPage Today) -- Clinical studies to date "do not provide unambiguous evidence" for SRP-9001 (delandistrogene moxeparvovec), an investigational gene therapy for ambulatory Duchenne muscular dystrophy patients, FDA reviewers said in briefing documents... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - May 10, 2023 Category: American Health Source Type: news
Britain's first three-parent baby is born: Procedure 'marks biggest leap forward' since IVF created
The technique, called mitochondrial donation treatment (MDT), protects children from a group of mitochondrial disorders, including muscular dystrophy. (Source: the Mail online | Health)
Source: the Mail online | Health - May 10, 2023 Category: Consumer Health News Source Type: news
America Spends Less On Its Military Than You Think. Look At The Numbers
Washington is embroiled in one of its periodic budget impasses as Democrats and Republicans struggle to impose their priorities. If hard choices need to be made, the usual reflex is for conservatives to attack welfare and progressives to attack warfare. It is never hard to find a faction on the…#democrats #republicans #pentagon #walmart #army #navy #usspending #armageddon #spending #missiledefenseagency (Source: Reuters: Health)
Source: Reuters: Health - May 4, 2023 Category: Consumer Health News Source Type: news
Age-related changes in prepulse inhibition of the startle response - de Oliveira YG, Poltronieri BC, Woodruff E, da Costa BF, Panizzutti RA.
INTRODUCTION: Acoustic prepulse inhibition of the startle response (PPI) is a phenomenon characterized by the reduction in the startle reflex caused by the presence of weak and brief stimulus before an intense and sudden stimulus (pulse). These phenomena c... (Source: SafetyLit)
Source: SafetyLit - May 4, 2023 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
FSHD1 Rare Neuromuscular Disorder Diagnosis Brings Answers for Teen
A rare neuromuscular disorder diagnosis of Facioscapulohumeral Muscular Dystrophy (FSHD) brings long awaited answers for teenager (Source: Disabled World)
Source: Disabled World - May 1, 2023 Category: Disability Tags: Muscular Dystrophy (MD) Source Type: news
Small acts of kindness are frequent and universal, study finds
Key takeawaysA study by researchers from UCLA, Australia, Ecuador, Germany, the Netherlands and the U.K. found that people around the world signal others for assistance every couple of minutes.The research, which examined behaviors in towns and rural areas in several different countries, revealed that people comply with these small requests for help far more often than they decline them.The findings suggest that people from all cultures have more similar cooperative behaviors than prior research has established.A new study by UCLA sociologist Giovanni Rossi and an international team of collaborators finds that people r...
Source: UCLA Newsroom: Health Sciences - April 21, 2023 Category: Universities & Medical Training Source Type: news
Artificial proprioceptive reflex warning using EMG in advanced driving assistance system - Hussain MI, Rafique MA, Kim J, Jeon M, Pedrycz W.
A frequent cause of auto accidents is disregarding the proximal traffic of an ego-vehicle during lane changing. Presumably, in a split-second-decision situation we may prevent an accident by predicting the intention of a driver before her action onset usin... (Source: SafetyLit)
Source: SafetyLit - April 13, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Hay fever: Excessive eye rubbing could lead to 'serious' complications, warns expert
Though rubbing the eyes seems like a natural reflex, it may actually do more harm than good in the long term. (Source: Daily Express - Health)
Source: Daily Express - Health - April 2, 2023 Category: Consumer Health News Source Type: news
Fox News breaks with Trump over his Jan. 6 obsession
A prominent Fox News host broke with former President Donald Trump over the sympathetic stance he's shared toward imprisoned Jan. 6 rioters at his Waco rally over the weekend. Speaking on the network's flagship morning show Fox and Friends on Monday, host Brian Kilmeade criticized the current…#donaldtrump #briankilmeade #trump #harrisfaulkner #manhattan #stormydaniels #florida #rondesantis #waco (Source: Reuters: Health)
Source: Reuters: Health - March 27, 2023 Category: Consumer Health News Source Type: news
What are Presentations of Neuroblastoma?
Discussion
Abdominal pain is a very common problem with abdominal masses being somewhat less common. If one considers how frequently patients have abdominal pain due to constipation and that it often presents with a fecal mass, both of these are commonplace. Abdominal and pelvic organs are sometimes mistaken for masses also. As the abdominal and pelvic cavities are large, tumors often need to be quite large before they cause functional problems and/or can be palpated on physical examination.
A review of abdominal masses can be found here.
A review of recurrent abdominal pain can be found here.
A review of acute abdominal p...
Source: PediatricEducation.org - March 27, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Millennial Canadians dealt generational losing hand, layered in debt: insolvency trustee
Insolvency trustee Doug Hoyes encounters a lot of Canadians with money troubles, but he's become particularly sympathetic to the plight of young people who find themselves financially underwater. For more than a decade, his Ontario-based firm Hoyes Michalos has been crunching bankruptcy and…#doughoyes #canadians #ontario #hoyesmichalos #joedebtor #cerb #hoyes #sandrafry #winnipeg #fry (Source: Reuters: Health)
Source: Reuters: Health - March 26, 2023 Category: Consumer Health News Source Type: news
Quantitative pupillary light reflex assessment for prognosis of carbon monoxide poisoning - Cha YS, Ko SB, Go TH, Lee DK.
BACKGROUND: A non-reactive pupil in standard pupillary light reflex (sPLR) is regarded as a factor predicting neurological sequelae at 1-month after carbon monoxide (CO) poisoning. An automated pupillometer is used in the intensive care unit to quantitativ... (Source: SafetyLit)
Source: SafetyLit - March 25, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
New four year data for Roche ’s Evrysdi reinforce long-term efficacy and safety profile in some of the most severely affected people with types 2 and 3 spinal muscular atrophy (SMA)
Data from pivotal SUNFISH study showed increases in motor function observed during the first year were maintained through the fourth year, while the overall rate of adverse events continued to decreaseData confirm long-term efficacy and safety profile ofEvrysdi in a broad range of people with Type 2 and non‑ambulant Type 3 SMAMore than 8,500 people —from newborns to the over 60s—have been treated withEvrysdi, which is now approved in more than 90 countries worldwideBasel, 20 March 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new long-term data for Evrysdi ® (risdiplam) in a broad range of people aged 2-...
Source: Roche Investor Update - March 20, 2023 Category: Pharmaceuticals Source Type: news
