Suppression of nitric oxide synthase aggravates non-alcoholic steatohepatitis and atherosclerosis in SHRSP5/Dmcr rat via acceleration of abnormal lipid metabolism

CONCLUSIONS: NOS inhibition simultaneously aggravates NASH and atherosclerosis via hepatic lipid and cholesterol metabolism.PMID:35819592 | DOI:10.1007/s43440-022-00380-1

Source: Pharmacological Reports - July 12, 2022 Category: Drugs & Pharmacology Authors: Ikumi Sato Shusei Yamamoto Mai Kakimoto Moe Fujii Koki Honma Shota Kumazaki Mami Matsui Hinako Nakayama Sora Kirihara Shang Ran Shinichi Usui Ryoko Shinohata Kazuya Kitamori Satoshi Hirohata Shogo Watanabe Source Type: research