Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae)
Exp Parasitol. 2023 Dec 1:108657. doi: 10.1016/j.exppara.2023.108657. Online ahead of print.ABSTRACTAedes aegypti serves as the primary vector for viruses like dengue, Chikungunya, Zika, and yellow fever, posing a significant public health challenge in Brazil. Given the absence of approved vaccines for these diseases, effective mosquito control becomes paramount in preventing outbreaks. However, currently available chemical insecticides face issues related to toxicity and the emergence of resistance, necessitating the exploration of new active compounds. Drawing inspiration from natural products, we identified the 1,3-benz...
Source: Experimental Parasitology - December 3, 2023 Category: Parasitology Authors: Mariza Severina de Lima Silva Marcilene Souza da Silva R ômulo Carlos Dantas da Cruz Bruno de Oliveira Veras Ivone Antonia de Souza Rafael Matos Ximenes Thiago Mendon ça de Aquino Alexandre Jos é da Silva Góes Source Type: research
Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae)
Exp Parasitol. 2023 Dec 1:108657. doi: 10.1016/j.exppara.2023.108657. Online ahead of print.ABSTRACTAedes aegypti serves as the primary vector for viruses like dengue, Chikungunya, Zika, and yellow fever, posing a significant public health challenge in Brazil. Given the absence of approved vaccines for these diseases, effective mosquito control becomes paramount in preventing outbreaks. However, currently available chemical insecticides face issues related to toxicity and the emergence of resistance, necessitating the exploration of new active compounds. Drawing inspiration from natural products, we identified the 1,3-benz...
Source: Experimental Parasitology - December 3, 2023 Category: Parasitology Authors: Mariza Severina de Lima Silva Marcilene Souza da Silva R ômulo Carlos Dantas da Cruz Bruno de Oliveira Veras Ivone Antonia de Souza Rafael Matos Ximenes Thiago Mendon ça de Aquino Alexandre Jos é da Silva Góes Source Type: research
Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae)
Exp Parasitol. 2023 Dec 1:108657. doi: 10.1016/j.exppara.2023.108657. Online ahead of print.ABSTRACTAedes aegypti serves as the primary vector for viruses like dengue, Chikungunya, Zika, and yellow fever, posing a significant public health challenge in Brazil. Given the absence of approved vaccines for these diseases, effective mosquito control becomes paramount in preventing outbreaks. However, currently available chemical insecticides face issues related to toxicity and the emergence of resistance, necessitating the exploration of new active compounds. Drawing inspiration from natural products, we identified the 1,3-benz...
Source: Experimental Parasitology - December 3, 2023 Category: Parasitology Authors: Mariza Severina de Lima Silva Marcilene Souza da Silva R ômulo Carlos Dantas da Cruz Bruno de Oliveira Veras Ivone Antonia de Souza Rafael Matos Ximenes Thiago Mendon ça de Aquino Alexandre Jos é da Silva Góes Source Type: research
Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae)
Exp Parasitol. 2023 Dec 1:108657. doi: 10.1016/j.exppara.2023.108657. Online ahead of print.ABSTRACTAedes aegypti serves as the primary vector for viruses like dengue, Chikungunya, Zika, and yellow fever, posing a significant public health challenge in Brazil. Given the absence of approved vaccines for these diseases, effective mosquito control becomes paramount in preventing outbreaks. However, currently available chemical insecticides face issues related to toxicity and the emergence of resistance, necessitating the exploration of new active compounds. Drawing inspiration from natural products, we identified the 1,3-benz...
Source: Experimental Parasitology - December 3, 2023 Category: Parasitology Authors: Mariza Severina de Lima Silva Marcilene Souza da Silva R ômulo Carlos Dantas da Cruz Bruno de Oliveira Veras Ivone Antonia de Souza Rafael Matos Ximenes Thiago Mendon ça de Aquino Alexandre Jos é da Silva Góes Source Type: research
Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae)
Exp Parasitol. 2023 Dec 1:108657. doi: 10.1016/j.exppara.2023.108657. Online ahead of print.ABSTRACTAedes aegypti serves as the primary vector for viruses like dengue, Chikungunya, Zika, and yellow fever, posing a significant public health challenge in Brazil. Given the absence of approved vaccines for these diseases, effective mosquito control becomes paramount in preventing outbreaks. However, currently available chemical insecticides face issues related to toxicity and the emergence of resistance, necessitating the exploration of new active compounds. Drawing inspiration from natural products, we identified the 1,3-benz...
Source: Experimental Parasitology - December 3, 2023 Category: Parasitology Authors: Mariza Severina de Lima Silva Marcilene Souza da Silva R ômulo Carlos Dantas da Cruz Bruno de Oliveira Veras Ivone Antonia de Souza Rafael Matos Ximenes Thiago Mendon ça de Aquino Alexandre Jos é da Silva Góes Source Type: research
Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae)
Exp Parasitol. 2023 Dec 1:108657. doi: 10.1016/j.exppara.2023.108657. Online ahead of print.ABSTRACTAedes aegypti serves as the primary vector for viruses like dengue, Chikungunya, Zika, and yellow fever, posing a significant public health challenge in Brazil. Given the absence of approved vaccines for these diseases, effective mosquito control becomes paramount in preventing outbreaks. However, currently available chemical insecticides face issues related to toxicity and the emergence of resistance, necessitating the exploration of new active compounds. Drawing inspiration from natural products, we identified the 1,3-benz...
Source: Experimental Parasitology - December 3, 2023 Category: Parasitology Authors: Mariza Severina de Lima Silva Marcilene Souza da Silva R ômulo Carlos Dantas da Cruz Bruno de Oliveira Veras Ivone Antonia de Souza Rafael Matos Ximenes Thiago Mendon ça de Aquino Alexandre Jos é da Silva Góes Source Type: research
Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae)
Exp Parasitol. 2023 Dec 1:108657. doi: 10.1016/j.exppara.2023.108657. Online ahead of print.ABSTRACTAedes aegypti serves as the primary vector for viruses like dengue, Chikungunya, Zika, and yellow fever, posing a significant public health challenge in Brazil. Given the absence of approved vaccines for these diseases, effective mosquito control becomes paramount in preventing outbreaks. However, currently available chemical insecticides face issues related to toxicity and the emergence of resistance, necessitating the exploration of new active compounds. Drawing inspiration from natural products, we identified the 1,3-benz...
Source: Experimental Parasitology - December 3, 2023 Category: Parasitology Authors: Mariza Severina de Lima Silva Marcilene Souza da Silva R ômulo Carlos Dantas da Cruz Bruno de Oliveira Veras Ivone Antonia de Souza Rafael Matos Ximenes Thiago Mendon ça de Aquino Alexandre Jos é da Silva Góes Source Type: research
Development and pre-clinical evaluation of a Zika virus diagnostic for low resource settings
DiscussionContrary to conventional RT-qPCR, our Iso-ZIKV-Dx does not require expensive machinery, specialised laboratory settings or extensively trained personnel. Pre-clinical evaluation demonstrates that our test exhibits robust, in-field capabilities without compromising sensitivity or specificity. When compared to the gold-standard RT-qPCR, our Iso-ZIKV-Dx test offers an array of applications that extend beyond diagnostics alone, including potential for surveillance and monitoring of ZIKV vector competency. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - November 20, 2023 Category: Microbiology Source Type: research
Viruses, Vol. 15, Pages 2244: Does the Presence or a High Titer of Yellow Fever Virus Antibodies Interfere with Pregnancy Outcomes in Women with Zika Virus Infection?
ças Costa Alecrim
Camila Helena Aguiar Bôtto de Menezes
Márcia da Costa Castilho
Djane Clarys Baia-da-Silva
Flor Ernestina Martinez Espinosa
Zika virus (ZIKV) and yellow fever virus (YFV) originated in Africa and expanded to the Americas, where both are co-circulated. It is hypothesized that in areas of high circulation and vaccination coverage against YFV, children of pregnant women have a lower risk of microcephaly. We evaluated the presence and titers of antibodies and outcomes in women who had ZIKV infection during pregnancy. Pregnancy outcomes were classified as severe, moderate, and without any importa...
Source: Viruses - November 11, 2023 Category: Virology Authors: Isa Cristina Ribeiro Piauilino Raillon Keven dos Santos Souza Maur ício Teixeira Lima Yanka Karolinna Batista Rodrigues Lu ís Felipe Alho da Silva Ayrton Sena Gouveia Alexandre Vilhena da Silva Neto B árbara Aparecida Chaves Maria das Gra ças Costa Al Tags: Brief Report Source Type: research
Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus
In this study, we assessed the larvicidal activity of commonly found seaweeds, including Padina gymnospora, P. pavonica, Gracilaria crassa, Amphiroa fragilissima, and Spatoglossum marginatum, against these mosquito vectors. Our findings indicate that extracts from P. gymnospora Ethyl Acetate (PgEA), P. pavonica Hexane (PpH), and A. fragilissima Ethyl Acetate (AfEA) displayed the highest larval mortality rates for A. stephensi, with LC50 values of 10.51, 12.43, and 6.43 μg/mL, respectively. Additionally, the PgEA extract from P. gymnospora exhibited the highest mortality rate for A. aegypti, with an LC50 of 27.0 μg/mL, wh...
Source: Experimental Parasitology - November 9, 2023 Category: Parasitology Authors: Annamalai Aravinth Sundaramoorthy Dhanasundaram Pachiappan Perumal Chinnaperumal Kamaraj Safir Ullah Khan Amir Ali Chinnasamy Ragavendran Vadivel Amutha Rajendran Rajaram Perumal Santhanam Juan Pedro Luna-Arias Zia-Ur-Rehman Mashwani Source Type: research
Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus
In this study, we assessed the larvicidal activity of commonly found seaweeds, including Padina gymnospora, P. pavonica, Gracilaria crassa, Amphiroa fragilissima, and Spatoglossum marginatum, against these mosquito vectors. Our findings indicate that extracts from P. gymnospora Ethyl Acetate (PgEA), P. pavonica Hexane (PpH), and A. fragilissima Ethyl Acetate (AfEA) displayed the highest larval mortality rates for A. stephensi, with LC50 values of 10.51, 12.43, and 6.43 μg/mL, respectively. Additionally, the PgEA extract from P. gymnospora exhibited the highest mortality rate for A. aegypti, with an LC50 of 27.0 μg/mL, wh...
Source: Experimental Parasitology - November 9, 2023 Category: Parasitology Authors: Annamalai Aravinth Sundaramoorthy Dhanasundaram Pachiappan Perumal Chinnaperumal Kamaraj Safir Ullah Khan Amir Ali Chinnasamy Ragavendran Vadivel Amutha Rajendran Rajaram Perumal Santhanam Juan Pedro Luna-Arias Zia-Ur-Rehman Mashwani Source Type: research
Fractional Dosing of Yellow Fever Live Attenuated 17D Vaccine: A Perspective
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - November 8, 2023 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Critical Review on Balanites aegyptiaca Delile: Phytoconstituents, Pharmacological Properties and Nanointerventions
AbstractBalanites aegyptiaca Delile (BA) is an enduring xerophytic woody and spinous flowering tree and is commonly known as desert date or Ingudi (Hingot). It belongs to the familyZygophyllaceae, which is specific to be drought areas of Nigeria, Africa, South Asia and India (Rajasthan). In Ayurveda, this traditional medicinal plant is reported for the management of jaundice, syphilis, yellow fever, metabolic disorders, liver, and spleen problems. The main aim of the review is to compile its medicinal uses and further advancements to showcase the promises inherited in various parts of the plant for the benefit of mankind.A...
Source: Chinese Journal of Integrative Medicine - November 6, 2023 Category: Internal Medicine Source Type: research
