Implementation of a vaccination clinic for adult solid organ transplant candidates: A single-center experience
Vaccine. 2023 Sep 27:S0264-410X(23)01106-4. doi: 10.1016/j.vaccine.2023.09.036. Online ahead of print.ABSTRACTVaccination is an evidence-based strategy to prevent or reduce the severity of infectious diseases (ID). Here, we aimed to describe the experience of implementing a vaccination clinic specifically targeting liver, heart, lung, and combined dual organ transplantation at a single transplantation center in Denmark. In this cohort of 242 solid organ transplant (SOT) candidates, we investigated seroprotection and the proportion of recommended vaccinations documented before transplantation. Furthermore, we registered com...
Source: Vaccine - September 29, 2023 Category: Allergy & Immunology Authors: Zitta Barrella Harboe Annemette Hald Christina Ekenberg Neval Ete Wareham Lene Fogt Lundbo Jon Gitz Holler Tavs Qvist Sebastian Rask Hamm Stephanie Bjerrum Omid Rezahosseini Paul Suno Krohn Finn Gustafsson Michael Perch Allan Rasmussen Susanne Dam Nielsen Source Type: research
Viruses, Vol. 15, Pages 2013: A Bioreactor-Based Yellow Fever Virus-Like Particle Production Process with Integrated Process Analytical Technology Based on Transient Transfection
Denise Salzig
Yellow Fever (YF) is a severe disease that, while preventable through vaccination, lacks rapid intervention options for those already infected. There is an urgent need for passive immunization techniques using YF-virus-like particles (YF-VLPs). To address this, we successfully established a bioreactor-based production process for YF-VLPs, leveraging transient transfection and integrating Process Analytical Technology. A cornerstone of this approach was the optimization of plasmid DNA (pDNA) production to a yield of 11 mg/L using design of experiments. Glucose, NaCl, yeast extract, and a phosphate buffer s...
Source: Viruses - September 27, 2023 Category: Virology Authors: Gregor Dekevic Tobias Tertel Lars Tasto Deborah Schmidt Bernd Giebel Peter Czermak Denise Salzig Tags: Article Source Type: research
Standardization, validation, and comparative evaluation of a faster and high-performance test for quantification of yellow fever neutralizing antibodies
This study aimed to standardize, validate, and compare it with the reference method in 6-well plates (PRNT). Once the execution protocol was standardized, precision, accuracy, selectivity, and robustness were evaluated to validate the μFRN-HRP. In addition, 200 sera of vaccinees were processed by the μFRN-HRP and by the micro-PRNT to compare with the reference test, estimating agreement by Intraclass Correlation Coefficient (ICC). The standardization and validation of the μFRN-HRP was carried out successfully. Weak to moderate agreement was observed between μFRN-HRP and PRNT for titers in reciprocal dilution, while the...
Source: Journal of Immunological Methods - September 25, 2023 Category: Allergy & Immunology Authors: Marisol Sim ões Stephanie Almeida da Silva Kelly Ara újo Lúcio Renan de Oliveira Vieira Waleska Dias Schwarcz Sheila Maria Barbosa de Lima Luiz Antonio Bastos Camacho Source Type: research
Standardization, validation, and comparative evaluation of a faster and high-performance test for quantification of yellow fever neutralizing antibodies
This study aimed to standardize, validate, and compare it with the reference method in 6-well plates (PRNT). Once the execution protocol was standardized, precision, accuracy, selectivity, and robustness were evaluated to validate the μFRN-HRP. In addition, 200 sera of vaccinees were processed by the μFRN-HRP and by the micro-PRNT to compare with the reference test, estimating agreement by Intraclass Correlation Coefficient (ICC). The standardization and validation of the μFRN-HRP was carried out successfully. Weak to moderate agreement was observed between μFRN-HRP and PRNT for titers in reciprocal dilution, while the...
Source: Journal of Immunological Methods - September 25, 2023 Category: Allergy & Immunology Authors: Marisol Sim ões Stephanie Almeida da Silva Kelly Ara újo Lúcio Renan de Oliveira Vieira Waleska Dias Schwarcz Sheila Maria Barbosa de Lima Luiz Antonio Bastos Camacho Source Type: research
Standardization, validation, and comparative evaluation of a faster and high-performance test for quantification of yellow fever neutralizing antibodies
This study aimed to standardize, validate, and compare it with the reference method in 6-well plates (PRNT). Once the execution protocol was standardized, precision, accuracy, selectivity, and robustness were evaluated to validate the μFRN-HRP. In addition, 200 sera of vaccinees were processed by the μFRN-HRP and by the micro-PRNT to compare with the reference test, estimating agreement by Intraclass Correlation Coefficient (ICC). The standardization and validation of the μFRN-HRP was carried out successfully. Weak to moderate agreement was observed between μFRN-HRP and PRNT for titers in reciprocal dilution, while the...
Source: Journal of Immunological Methods - September 25, 2023 Category: Allergy & Immunology Authors: Marisol Sim ões Stephanie Almeida da Silva Kelly Ara újo Lúcio Renan de Oliveira Vieira Waleska Dias Schwarcz Sheila Maria Barbosa de Lima Luiz Antonio Bastos Camacho Source Type: research
Standardization, validation, and comparative evaluation of a faster and high-performance test for quantification of yellow fever neutralizing antibodies
This study aimed to standardize, validate, and compare it with the reference method in 6-well plates (PRNT). Once the execution protocol was standardized, precision, accuracy, selectivity, and robustness were evaluated to validate the μFRN-HRP. In addition, 200 sera of vaccinees were processed by the μFRN-HRP and by the micro-PRNT to compare with the reference test, estimating agreement by Intraclass Correlation Coefficient (ICC). The standardization and validation of the μFRN-HRP was carried out successfully. Weak to moderate agreement was observed between μFRN-HRP and PRNT for titers in reciprocal dilution, while the...
Source: Journal of Immunological Methods - September 25, 2023 Category: Allergy & Immunology Authors: Marisol Sim ões Stephanie Almeida da Silva Kelly Ara újo Lúcio Renan de Oliveira Vieira Waleska Dias Schwarcz Sheila Maria Barbosa de Lima Luiz Antonio Bastos Camacho Source Type: research
Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India
This study was carried out to check the degree of resistance among these vectors in the Chittorgarh district of Rajasthan, India through standard World Health Organization protocol. The resistance was monitored to pyrethroids i.e., deltamethrin (0.05%), permethrin (0.75%), alphacypermethrin (0.05%); organochlorine i.e., DDT (4%), and an organophosphate larvicide i.e., temephos (0.02 mg/L) in both vector species. Complete resistance to DDT was observed among all tested populations of both species. All tested populations of Aedes albopictus were found susceptible to pyrethroids. Aedes aegypti was found resistant in the Manga...
Source: Experimental Parasitology - September 22, 2023 Category: Parasitology Authors: Pradeep Kumar Jangir Arti Prasad Source Type: research
Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India
This study was carried out to check the degree of resistance among these vectors in the Chittorgarh district of Rajasthan, India through standard World Health Organization protocol. The resistance was monitored to pyrethroids i.e., deltamethrin (0.05%), permethrin (0.75%), alphacypermethrin (0.05%); organochlorine i.e., DDT (4%), and an organophosphate larvicide i.e., temephos (0.02 mg/L) in both vector species. Complete resistance to DDT was observed among all tested populations of both species. All tested populations of Aedes albopictus were found susceptible to pyrethroids. Aedes aegypti was found resistant in the Manga...
Source: Experimental Parasitology - September 22, 2023 Category: Parasitology Authors: Pradeep Kumar Jangir Arti Prasad Source Type: research
Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India
This study was carried out to check the degree of resistance among these vectors in the Chittorgarh district of Rajasthan, India through standard World Health Organization protocol. The resistance was monitored to pyrethroids i.e., deltamethrin (0.05%), permethrin (0.75%), alphacypermethrin (0.05%); organochlorine i.e., DDT (4%), and an organophosphate larvicide i.e., temephos (0.02 mg/L) in both vector species. Complete resistance to DDT was observed among all tested populations of both species. All tested populations of Aedes albopictus were found susceptible to pyrethroids. Aedes aegypti was found resistant in the Manga...
Source: Experimental Parasitology - September 22, 2023 Category: Parasitology Authors: Pradeep Kumar Jangir Arti Prasad Source Type: research
Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India
This study was carried out to check the degree of resistance among these vectors in the Chittorgarh district of Rajasthan, India through standard World Health Organization protocol. The resistance was monitored to pyrethroids i.e., deltamethrin (0.05%), permethrin (0.75%), alphacypermethrin (0.05%); organochlorine i.e., DDT (4%), and an organophosphate larvicide i.e., temephos (0.02 mg/L) in both vector species. Complete resistance to DDT was observed among all tested populations of both species. All tested populations of Aedes albopictus were found susceptible to pyrethroids. Aedes aegypti was found resistant in the Manga...
Source: Experimental Parasitology - September 22, 2023 Category: Parasitology Authors: Pradeep Kumar Jangir Arti Prasad Source Type: research
Evolution of knockdown resistance (kdr) mutations of Aedes aegypti and Aedes albopictus in Hainan Island and Leizhou Peninsula, China
ConclusionThe study of kdr gene evolution in the two mosquito species may help to identify the evolutionary trend of insecticide resistance at an early stage and provide a theoretical basis for improving the efficiency of biological vector control and subsequent research into new insecticides. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - September 21, 2023 Category: Microbiology Source Type: research
Vaccination coverage in children under one year of age and associated socioeconomic factors: maps of spatial heterogeneity
CONCLUSIONS: the results are useful for designing interventions regarding the structuring of vaccination services and the implementation of actions to increase vaccination coverage in clusters with less propensity to vaccinate.PMID:37729269 | DOI:10.1590/0034-7167-2022-0734 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - September 20, 2023 Category: Nursing Authors: Matheus Adriano Divino Pereira Luis Henrique Arroyo Maria Del Pilar Serrano Gallardo Ricardo Alexandre Arc êncio Josianne Dias Gusm ão Gabriela Gon çalves Amaral Val éria Conceição de Oliveira Eliete Albano de Azevedo Guimar ães Source Type: research
Vaccination coverage in children under one year of age and associated socioeconomic factors: maps of spatial heterogeneity
CONCLUSIONS: the results are useful for designing interventions regarding the structuring of vaccination services and the implementation of actions to increase vaccination coverage in clusters with less propensity to vaccinate.PMID:37729269 | DOI:10.1590/0034-7167-2022-0734 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - September 20, 2023 Category: Nursing Authors: Matheus Adriano Divino Pereira Luis Henrique Arroyo Maria Del Pilar Serrano Gallardo Ricardo Alexandre Arc êncio Josianne Dias Gusm ão Gabriela Gon çalves Amaral Val éria Conceição de Oliveira Eliete Albano de Azevedo Guimar ães Source Type: research
Vaccination coverage in children under one year of age and associated socioeconomic factors: maps of spatial heterogeneity
CONCLUSIONS: the results are useful for designing interventions regarding the structuring of vaccination services and the implementation of actions to increase vaccination coverage in clusters with less propensity to vaccinate.PMID:37729269 | PMC:PMC10506597 | DOI:10.1590/0034-7167-2022-0734 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - September 20, 2023 Category: Nursing Authors: Matheus Adriano Divino Pereira Luis Henrique Arroyo Maria Del Pilar Serrano Gallardo Ricardo Alexandre Arc êncio Josianne Dias Gusm ão Gabriela Gon çalves Amaral Val éria Conceição de Oliveira Eliete Albano de Azevedo Guimar ães Source Type: research
Vaccination coverage in children under one year of age and associated socioeconomic factors: maps of spatial heterogeneity
CONCLUSIONS: the results are useful for designing interventions regarding the structuring of vaccination services and the implementation of actions to increase vaccination coverage in clusters with less propensity to vaccinate.PMID:37729269 | PMC:PMC10506597 | DOI:10.1590/0034-7167-2022-0734 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - September 20, 2023 Category: Nursing Authors: Matheus Adriano Divino Pereira Luis Henrique Arroyo Maria Del Pilar Serrano Gallardo Ricardo Alexandre Arc êncio Josianne Dias Gusm ão Gabriela Gon çalves Amaral Val éria Conceição de Oliveira Eliete Albano de Azevedo Guimar ães Source Type: research
