Premenstrual flares of pyoderma gangrenosum controlled with use of a combined oral contraceptive and antiandrogen (ethinyl estradiol/drospirenone)
We report the case of a 34‐year‐old woman with chronic PG leg ulcers who was found to have recurring, premenstrual flares of PG. Her PG flares were controlled with the use of ethinyl estradiol/drospirenone. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - January 28, 2016 Category: Dermatology Authors: N. Jourabchi, S.M. Rhee, G.S. Lazarus Tags: Case Report Source Type: research
Pre-menstrual flares of pyoderma gangrenosum controlled with use of a combined oral contraceptive and antiandrogen (Ethinyl Estradiol/Drospirenone).
This article is protected by copyright. All rights reserved.
PMID: 26616160 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - November 30, 2015 Category: Dermatology Authors: Jourabchi N, Rhee SM, Lazarus GS Tags: Br J Dermatol Source Type: research
Pre‐menstrual flares of pyoderma gangrenosum controlled with use of a combined oral contraceptive and antiandrogen (Ethinyl Estradiol/Drospirenone)
This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 30, 2015 Category: Dermatology Authors: N. Jourabchi, S.M. Rhee, G.S. Lazarus Tags: Case Report Source Type: research
Hormonal therapy with estradiol and drospirenone improves endothelium-dependent vasodilation in the coronary bed of ovariectomized spontaneously hypertensive rats.
This study investigated the effects of combined therapy with estrogen (E2) and DRSP on endothelium-dependent vasodilation of the coronary bed of ovariectomized (OVX) spontaneously hypertensive rats. Female spontaneously hypertensive rats (n=87) at 12 weeks of age were randomly divided into sham operated (Sham), OVX, OVX treated with E2 (E2), and OVX treated with E2 and DRSP (E2+DRSP) groups. Hemodynamic parameters were directly evaluated by catheter insertion into the femoral artery. Endothelium-dependent vasodilation in response to bradykinin in the coronary arterial bed was assessed using isolated hearts according to a m...
Source: Braz J Med Biol Res - November 20, 2015 Category: Research Authors: Borgo MV, Claudio ER, Silva FB, Romero WG, Gouvea SA, Moysés MR, Santos RL, Almeida SA, Podratz PL, Graceli JB, Abreu GR Tags: Braz J Med Biol Res Source Type: research
Comparison of two contraceptive pills containing drospirenone and 20μg or 30μg ethinyl estradiol for polycystic ovary syndrome
Conclusion Among patients with PCOS, an oral contraceptive pill containing 20μg EE has similar effects on androgen levels to those of a pill containing 30μg. Clinical Trial Registration Number: CTRI/2012/04/002571 (Source: International Journal of Gynecology and Obstetrics)
Source: International Journal of Gynecology and Obstetrics - November 7, 2015 Category: OBGYN Source Type: research
Comparison of two contraceptive pills containing drospirenone and 20μg or 30μg ethinyl estradiol for polycystic ovary syndrome
To compare the effects of 30μg and 20μg ethinyl estradiol (EE) among women with polycystic ovary syndrome (PCOS). (Source: International Journal of Gynaecology and Obstetrics)
Source: International Journal of Gynaecology and Obstetrics - November 5, 2015 Category: OBGYN Authors: Sudhindra M. Bhattacharya, Ayan Jha, Lipika DasMukhopadhyay Tags: Clinical article Source Type: research
Inhibition of ovulation by administration of estetrol in combination with drospirenone or levonorgestrel: Results of a phase II dose-finding pilot study.
Conclusions Combined with a progestin, E4 adequately suppresses ovarian activity, particularly when given at a dosage above 10 mg/day. Chinese Abstract -。 1835、，II，。24/4-,510/3;5,1020/150 μg;20 μg/3。13，,、、-。，。 109。。：20，/。。1721，。。 ，10/。 ；；；；.
PMID: 26394847 [PubMed - in process] (Source: The European Journal of Contraception and Reproductive Health Care)
Source: The European Journal of Contraception and Reproductive Health Care - September 25, 2015 Category: Reproduction Medicine Authors: Duijkers IJ, Klipping C, Zimmerman Y, Appels N, Jost M, Maillard C, Mawet M, Foidart JM, Coelingh Bennink HJ Tags: Eur J Contracept Reprod Health Care Source Type: research
Continuous Norethisterone Acetate versus Cyclical Drospirenone 3 mg/Ethinyl Estradiol 20 μg for the Management of Primary Dysmenorrhea in Young Adult Women
To evaluate the efficacy of continuous norethisterone acetate (NET-A), 5 mg (group N) vs cyclical combined oral contraceptive pill (COC) consisting of drospirenone 3 mg/ethinyl estradiol 20 μg pills (group P) in treating dysmenorrhea in young adult women. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - September 2, 2015 Category: OBGYN Authors: Moamar Al-Jefout, Nedal Nawaiseh Tags: Original Study Source Type: research
Continues Norethisterone Acetate versus Cyclical Drospirenone 3 mg/ethinyl Estradiol 20 μg for the Management of Primary Dysmenorrhea in Young Adult Females
To evaluate the efficacy of continues Norethisterone acetate, 5 mg (NET-A; group N) versus cyclical combined oral contraceptive pill (COC) consisting of drospirenone 3 mg/ethinyl estradiol 20 μg pills (group P) in treating dysmenorrhea in young adult females. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - September 2, 2015 Category: OBGYN Authors: Moamar Al-Jefout, Nedal Nawaiseh Source Type: research
Evaluation of Apelin and Insulin Resistance in Patients with PCOS and Therapeutic Effect of Drospirenone-Ethinylestradiol Plus Metformin.
CONCLUSIONS Apelin level significantly increased in PCOS patients. The combined therapy of DRSP-EE plus metformin not only decreases IR, but also improves apelin level. This combination is a superior approach for PCOS treatment.
PMID: 26314870 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - September 1, 2015 Category: Research Tags: Med Sci Monit Source Type: research
Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol
CONCLUSIONSA moderate pharmacokinetic drug‐drug interaction between DRSP and KTZ was demonstrated in this study. No relevant changes of medical concern were detected in the safety data collected in this study. This article is protected by copyright. All rights reserved. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - August 14, 2015 Category: Drugs & Pharmacology Authors: Herbert Wiesinger, Matthias Berse, Stefan Klein, Simone Gschwend, Joachim Höchel, Frank S. Zollmann, Barbara Schütt Tags: Drug Interactions Source Type: research
A randomised study comparing the effect on ovarian activity of a progestogen-only pill (POP) containing desogestrel and a new POP containing drospirenone in a 24/4 regimen.
Conclusions The new drospirenone-only pill inhibited ovulation as effectively as the desogestrel-only pill despite the 4-day hormone-free interval.
PMID: 26073333 [PubMed - as supplied by publisher] (Source: The European Journal of Contraception and Reproductive Health Care)
Source: The European Journal of Contraception and Reproductive Health Care - June 15, 2015 Category: Reproduction Medicine Authors: Duijkers IJ, Heger-Mahn D, Drouin D, Skouby S Tags: Eur J Contracept Reprod Health Care Source Type: research
Haemostatic and metabolic impact of estradiol pills and drospirenone-containing ethinylestradiol pills vs. levonorgestrel-containing ethinylestradiol pills: A literature review.
Conclusion E2/NOMAC exhibits less haemostatic and metabolic impact than EE/LNG and other COCs, suggesting that it may be a promising candidate to reduce residual VTE risk associated with COC use. Confirmation from a well-powered prospective clinical trial is, however, needed.
PMID: 26007631 [PubMed - as supplied by publisher] (Source: The European Journal of Contraception and Reproductive Health Care)
Source: The European Journal of Contraception and Reproductive Health Care - May 26, 2015 Category: Reproduction Medicine Authors: Lete I, Chabbert-Buffet N, Jamin C, Lello S, Lobo P, Nappi RE, Pintiaux A Tags: Eur J Contracept Reprod Health Care Source Type: research
Effects of a contraceptive containing drospirenone and ethinyl estradiol on blood pressure and autonomic tone: a prospective controlled clinical trial
Conclusion A contraceptive containing 20mcg of ethinyl estradiol and 3mg of drospirenone causes no significant changes in clinical, hemodynamic and autonomic parameters of normal women. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - March 22, 2015 Category: OBGYN Source Type: research
Comparative analysis of the effects of nomegestrol acetate/17 β-estradiol and drospirenone/ethinylestradiol on premenstrual and menstrual symptoms and dysmenorrhea.
Conclusions NOMAC/E2 was effective in reducing most premenstrual and menstrual symptoms, and was associated with significantly greater improvements in many MDQ-C domain scores compared with DRSP/EE. ( ClinicalTrials.gov : NCT00413062 and NCT00511199).
PMID: 25712537 [PubMed - as supplied by publisher] (Source: The European Journal of Contraception and Reproductive Health Care)
Source: The European Journal of Contraception and Reproductive Health Care - February 25, 2015 Category: Reproduction Medicine Authors: Witjes H, Creinin MD, Sundström-Poromaa I, Martin Nguyen A, Korver T Tags: Eur J Contracept Reprod Health Care Source Type: research
