Clinical effect of hormonal replacement therapy with estradiol associated with noretisterone or drospirenone. A prospective randomized placebo controlled study
Gynecological Endocrinology, Ahead of Print. (Source: Gynecological Endocrinology)
Source: Gynecological Endocrinology - February 23, 2015 Category: Endocrinology Tags: article Source Type: research

Effects of a contraceptive containing drospirenone and ethinylestradiol on blood pressure, metabolic profile and neurohumoral axis in hypertensive women at reproductive age
Conclusion A contraceptive containing 20mcg of ethinyl estradiol and 3mg of drospirenone causes no significant changes in clinical and autonomic parameters, metabolic variables and neurohumoral axis of hypertensive women. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 18, 2014 Category: OBGYN Source Type: research

Effects of estradiol-drospirenone on menopausal symptoms, lipids and bone turnover in Chinese women.
Conclusion Estradiol-drospirenone effectively alleviates menopausal symptoms, and also has beneficial effects on blood lipids and bone metabolism. PMID: 25362969 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - November 3, 2014 Category: Geriatrics Authors: Li M, Wang A, Hu L, Song Z, Zhao Y, Sun Y, Yan L, Li X Tags: Climacteric Source Type: research

The comparative study of Yaz and Ovocept-ld on patients with simple ovarian cysts referring to Iran-Isfahan Shariati Hospital.
CONCLUSION: Given the faster and better recovery effect, and the lesser side effects of Yaz as compared to Ovocept-LD, it is recommended to use Yaz for the simple ovarian cysts. PMID: 25337535 [PubMed] (Source: Biomed Res)
Source: Biomed Res - October 27, 2014 Category: Research Authors: Riahinejad S, Pour AF, Dehghani L, Hajizadeh S Tags: Adv Biomed Res Source Type: research

A multicenter, randomized phase III study comparing a 13.5 mg levonorgestrel intrauterine contraceptive system with a combined oral contraceptive: analysis of user satisfaction and safety
To compare user satisfaction and adverse events (AEs) with use of the 13.5 mg total content levonorgestrel intrauterine contraceptive system (LNG-IUS13.5mg) and a 30 μg ethinyl estradiol/3 mg drospirenone combined oral contraceptive (COC). (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2014 Category: Reproduction Medicine Authors: L. Borgatta, K. Roth, S. Rybowski, K. Rosen Source Type: research

Comparative study of the therapeutic effects of two different dosages of ethinyl estradiol (EE: 20 MCG versus 30 MCG) in association with drospirenone (DRSP: 3 mg) in polycystic ovary syndrome (PCOS)
To compare the therapeutic effects of two different dosages of Ethinyl estradiol (EE: 20 mcg versus 30 mcg) in combination with Drospirenone (DRSP: 3 mg) in polycystic ovary syndrome (PCOS) after 6 and 12 months of treatment. (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2014 Category: Reproduction Medicine Authors: S.M. Bhattacharya, A. Jha Source Type: research

A randomized phase III study comparing a new 13.5 mg levonorgestrel intrauterine contraceptive system with a combined oral contraceptive: analysis of efficacy and bleeding profiles
To compare contraceptive efficacy and bleeding profiles associated with use of the 13.5 mg (total content) levonorgestrel intrauterine contraceptive system (LNG-IUS13.5mg) and a 30 μg ethinyl estradiol and 3 mg drospirenone combined oral contraceptive (COC) in younger women. (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2014 Category: Reproduction Medicine Authors: L. Borgatta, K. Roth, S. Rybowski, K. Rosen Source Type: research

Low-dose oral or non-oral hormone therapy: effects on CRP and atrial natriuretic peptide in menopause.
Conclusions. Low-dose oral and non-oral HT for 6 months had neutral or beneficial effects in recent post-menopausal women with no clinical evidence of cardiovascular disease. PMID: 25017924 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - July 12, 2014 Category: Geriatrics Authors: Casanova G, Reis AM, Spritzer PM Tags: Climacteric Source Type: research

Effects of hormone replacement therapy on plasma and tissue fibrinolytic activity in a rat model of surgically induced menopause.
Conclusions: HRT showed beneficial effects by decreasing fibrinolytic activity related to surgically-induced menopause. Short-term HRT treatment was associated with a shift in the procoagulant-anticoagulant balance toward a procoagulant state. PMID: 24690423 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - April 4, 2014 Category: Biomedical Science Authors: Topcuoglu A, Albayrak M, Erman H, Balci H, Karakus M, Coban I, Uzun H Tags: Clin Invest Med Source Type: research

Comparison of the Impact of Four Generations of Progestins on Hemostatic Variables
This study was undertaken to evaluate the impact of progestins as part of low-estrogen (ethinyl estradiol [EE2] ≤35 μg) combined oral contraceptives (COCs) on hemostatic variables. One hundred ninety-five healthy women took oral contraceptives with following formulations: 35 EE2/norgestimate (NGM), 35 EE2/cyproterone acetate, 35 EE2/norethisterone, 30 EE2/levonorgestrel, 30 EE2/drospirenone (DRSP), 20 EE2/gestodene, and 20 EE2/DRSP, for 6 months. Hemostatic assays (prothrombin time, activated partial thromboplastin time, fibrinogen, resistance to activated protein C ratio, protein C, protein S, factor VIII [FVIII], a...
Source: Clinical and Applied Thrombosis/Hemostasis - April 2, 2014 Category: Hematology Authors: Oslakovic, S., Zadro, R. Tags: Original Articles Source Type: research

Acne vulgaris in the context of complex medical co-morbities: The Management of Severe Acne Vulgaris in a Female with Retinitis Pigmentosa- Utilizing Pulse Dye Laser in Conjunction with Medical Therapy.
We present a patient with severe acne vulgaris and a history of retinitis pigmentosa who was treated with 595 nanometer pulsed dye laser therapy, in conjunction with therapeutic alternatives to first-line acne medications. Our patient exhibited a significant and sustained improvement with the combined use of 595 nanometer pulsed dye laser, Yaz (drospirenone-ethinyl estradiol), dapsone, topical metronidazole, sodium-sulfacetamide wash, and topical azelaic acid. The positive results in this case, suggest that this combined treatment modality may serve as an example of a safe and effective treatment alternative in the managem...
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Shariff A, Keck L, Zlotoff B Tags: Dermatol Online J Source Type: research

The Effectiveness of Yaz and Yasmin Administered Orally and Vaginally for the Primary Treatment of Premenstrual Dysphoric Disorder
The objective of this study was to determine if Yaz and Yasmin when adminstered orally or vaginally exhibit similar effectiveness based on the daily record of severity problems scale. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 5, 2014 Category: OBGYN Authors: Jennifer Kurkowski, Jennifer E. Dietrich Tags: Poster Abstracts Source Type: research

Clitoral Vascularization and Sexual Behavior in Young Patients Treated with Drospirenone–Ethinyl Estradiol or Contraceptive Vaginal Ring: A Prospective, Randomized, Pilot Study
ConclusionsSix‐month treatment with hormonal contraception is associated with a diminished MFSQ score. However, the frequency of sexual intercourse and orgasm was reduced only by the use of OC. The OC use was associated with increased pain during intercourse. Battaglia C, Morotti E, Persico N, Battaglia B, Busacchi P, Casadio P, Paradisi R, and Venturoli S. Clitoral vascularization and sexual behavior in young patients treated with drospirenone–ethinyl estradiol or contraceptive vaginal ring: A prospective, randomized, pilot study. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - December 1, 2013 Category: Sexual Medicine Authors: Cesare Battaglia, Elena Morotti, Nicola Persico, Bruno Battaglia, Paolo Busacchi, Paolo Casadio, Roberto Paradisi, Stefano Venturoli Tags: Original Research Source Type: research

Evaluation of the efficacy of Fructus agni casti in women with severe primary dysmenorrhea: A prospective comparative Doppler study
ConclusionThe effectiveness of Fructus agni casti was similar to that of ethinyl estradiol/drospirenone in patients with primary dysmenorrhea. (Source: Journal of Obstetrics and Gynaecology Research)
Source: Journal of Obstetrics and Gynaecology Research - November 18, 2013 Category: OBGYN Authors: Ayse Nur Aksoy, Ilay Gözükara, Suna Kabil Kucur Tags: Original Article Source Type: research

Basal and Meal-Stimulated Ghrelin, PYY, CCK Levels and Satiety in Lean Women With Polycystic Ovary Syndrome: Effect of Low-Dose Oral Contraceptive.
Conclusions:Basal and stimulated hunger and satiety hormones in lean PCOS patients are not different from lean healthy women, except for a lower meal-stimulated ghrelin response. Short-term use of a low-dose oral contraceptive does not have an effect on appetite regulation of PCOS. PMID: 24001751 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - September 3, 2013 Category: Endocrinology Authors: Arusoglu G, Koksal G, Cinar N, Tapan S, Aksoy DY, Yildiz BO Tags: J Clin Endocrinol Metab Source Type: research