Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause
Expert Rev Clin Pharmacol. 2022 Mar 21. doi: 10.1080/17512433.2022.2054413. Online ahead of print.ABSTRACTINTRODUCTION: Estrogens used in women's healthcare have been associated with increased risks of venous thromboembolism (VTE) and breast cancer. Estetrol (E4), an estrogen produced by the human fetal liver, has recently been approved for the first time as a new estrogenic component of a novel combined oral contraceptive (E4/drospirenone [DRSP]) for over a decade. In phase 3 studies, E4/DRSP showed good contraceptive efficacy, a predictable bleeding pattern, and a favorable safety and tolerability profile.AREAS COVERED: ...
Source: Clinical Genitourinary Cancer - March 21, 2022 Category: Cancer & Oncology Authors: C éline Gerard Jean-Fran çois Arnal Maud Jost Jonathan Douxfils Fran çoise Lenfant Coralie Fontaine Ren é Houtman David F Archer Robert L Reid Rogerio A Lobo Ulysse Gaspard Herjan J T Coelingh Bennink Mitchell D Creinin Jean-Michel Foidart Source Type: research
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause
Expert Rev Clin Pharmacol. 2022 Mar 21. doi: 10.1080/17512433.2022.2054413. Online ahead of print.ABSTRACTINTRODUCTION: Estrogens used in women's healthcare have been associated with increased risks of venous thromboembolism (VTE) and breast cancer. Estetrol (E4), an estrogen produced by the human fetal liver, has recently been approved for the first time as a new estrogenic component of a novel combined oral contraceptive (E4/drospirenone [DRSP]) for over a decade. In phase 3 studies, E4/DRSP showed good contraceptive efficacy, a predictable bleeding pattern, and a favorable safety and tolerability profile.AREAS COVERED: ...
Source: Clinical Breast Cancer - March 21, 2022 Category: Cancer & Oncology Authors: C éline Gerard Jean-Fran çois Arnal Maud Jost Jonathan Douxfils Fran çoise Lenfant Coralie Fontaine Ren é Houtman David F Archer Robert L Reid Rogerio A Lobo Ulysse Gaspard Herjan J T Coelingh Bennink Mitchell D Creinin Jean-Michel Foidart Source Type: research
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause
Expert Rev Clin Pharmacol. 2022 Mar 21. doi: 10.1080/17512433.2022.2054413. Online ahead of print.ABSTRACTINTRODUCTION: Estrogens used in women's healthcare have been associated with increased risks of venous thromboembolism (VTE) and breast cancer. Estetrol (E4), an estrogen produced by the human fetal liver, has recently been approved for the first time as a new estrogenic component of a novel combined oral contraceptive (E4/drospirenone [DRSP]) for over a decade. In phase 3 studies, E4/DRSP showed good contraceptive efficacy, a predictable bleeding pattern, and a favorable safety and tolerability profile.AREAS COVERED: ...
Source: Expert Review of Clinical Pharmacology - March 21, 2022 Category: Drugs & Pharmacology Authors: C éline Gerard Jean-Fran çois Arnal Maud Jost Jonathan Douxfils Fran çoise Lenfant Coralie Fontaine Ren é Houtman David F Archer Robert L Reid Rogerio A Lobo Ulysse Gaspard Herjan J T Coelingh Bennink Mitchell D Creinin Jean-Michel Foidart Source Type: research
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause
Expert Rev Clin Pharmacol. 2022 Feb;15(2):121-137. doi: 10.1080/17512433.2022.2054413. Epub 2022 Mar 27.ABSTRACTINTRODUCTION: Estrogens used in women's healthcare have been associated with increased risks of venous thromboembolism (VTE) and breast cancer. Estetrol (E4), an estrogen produced by the human fetal liver, has recently been approved for the first time as a new estrogenic component of a novel combined oral contraceptive (E4/drospirenone [DRSP]) for over a decade. In phase 3 studies, E4/DRSP showed good contraceptive efficacy, a predictable bleeding pattern, and a favorable safety and tolerability profile.AREAS COV...
Source: Expert Review of Clinical Pharmacology - March 21, 2022 Category: Drugs & Pharmacology Authors: C éline Gérard Jean-Fran çois Arnal Maud Jost Jonathan Douxfils Fran çoise Lenfant Coralie Fontaine Ren é Houtman David F Archer Robert L Reid Rogerio A Lobo Ulysse Gaspard Herjan J T Coelingh Bennink Mitchell D Creinin Jean-Michel Foidart Source Type: research
