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Factors associated with insomnia in pregnancy: a prospective Cohort Study
Conclusions Insomnia prevalence was high from the beginning of pregnancy, associated with pre-gestational insomnia. In late pregnancy, two out of three pregnant women suffering insomnia. Insomnia prevention should be targeted particularly to those with high body mass index and pre-gestational insomnia. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Umbilical cord hemangioma: Sonographic features by HDlive Flow
Publication date: Available online 7 December 2017 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Youhei Akiba, Kei Miyakoshi, Daigo Ochiai, Miho Kawaida, Tadashi Matsumoto, Mamoru Tanaka (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Asymptomatic bacteriuria and urinary tract infection in pregnant women with and without diabetes: Cohort study
CONCLUSION In pregnant women with and women without DM or GDM, the overall prevalence of ASB was low. Neither ASB nor UTI did differ significantly between the groups. Our data discourage a routine ASB screen and treat policy in pregnant women with DM or GDM. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Cutaneous endometriosis: presentation of 33 cases and literature review
Conclusion Although it is a rare disease, its association with gynaecological surgery, and in particular caesarean section, means that there should be more awareness of this condition. Its diagnosis may be complicated due to lack of knowledge, when a proper examination and anamnesis can give us the key. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Epiploic appendagitis at term pregnancy. The importance of expert imaging: A case report
Publication date: Available online 9 December 2017 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Gabriel Levin, Amihai Rottenstreich, Lina Sabag (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Maternal Race/Ethnicity as a risk factor for cervical insufficiency
Conclusion Black women had higher odds of CI compared to White women. This disparity may contribute to the significantly higher rate of PTB among Black women nationally. Further investigation of this association may provide important contributions to our understanding of both CI and PTB. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Yield rate of Chromosomal Microarray Analysis in fetuses with congenital heart defects
Conclusion CMA increases the diagnostic yield in cases of CHD, regardless of whether it is isolated or not. CMA should be the modality of choice when investigating the genetic origin of CHDs until whole exome or genome sequencing is implemented into routine clinical practice. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Massive hematuria at pregnancy caused by ruptured angiomyolipoma: A case report
Publication date: Available online 14 December 2017 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Amihai Rottenstreich, Shmuel Herzberg, Roy Zigron, Ilana Parkes, Myriam Safrai, Gabriel Levin (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Outcome of Magnetic Resonance –Guided Focused Ultrasound Surgery (MRgFUS) for FIGO Class 1 fibroids
Conclusion This preliminary study shows that MRgFUS can be a feasible treatment option for FIGO class 1 uterine fibroids. Shrinkage of fibroids by MRgFUS can obviate or facilitate subsequent surgical intervention in selected cases. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Comparison of planned caesarean delivery and planned vaginal delivery in women with a twin pregnancy: a nation wide cohort study
Conclusion Planned VD results in comparable neonatal outcomes as planned CD for twin pregnancy with the first twin in cephalic position, even with a low intrapartum CD rate of 19.7%. At term, a planned CD may result in less asphyxia- and trauma related outcomes. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

The effect of intravesical instillations with Hyaluronic Acid on sexual dysfunction in women with recurrent urinary tract infections (RUTI)
Conclusion We have reinforced previous work showing the association between RUTI and sexual dysfunction, and an improvement in bladder symptoms following treatment with HA. To our knowledge, this is the first study to prove an improvement in sexual dysfunction following intravesical treatment with HA which is sustained for up to 12 months. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Association of the common SNPs in RNF212, STAG3 and RFX2 gene with male infertility with azoospermia in Chinese population
Publication date: Available online 15 December 2017 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Cheng-He Yu, Ting Xie, Ruo-Peng Zhang, Zhou-Cun A Objective The aim of this study was to explore the association between the SNP rs4045481 in RNF212 gene, rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene and male infertility with azoospermia in Chinese population. Study Design Two hundreds and twenty infertile patients with azoospermia and 248 fertile men were recruited in the present study. The four SNPs investigated were genotyped using polymerase chai...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

A prospective study of the frequency of severe pain and predictive factors in women undergoing first-trimester surgical abortion under local anaesthesia
CONCLUSION Nearly half of the women experienced severe pain. More than 10 weeks of gestation and parity were predictive factors of severe pain. These findings should be useful in counselling women undergoing surgical abortion under LA. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Outcomes of pregnancies achieved by double gamete donation: a comparison with pregnancies obtained by oocyte donation alone
Conclusion Women undergoing oocyte donation should be fully informed of its high rates of obstetric and perinatal risks. However, except for a higher observed risk of gestational diabetes, double donation does not appear to be associated with a higher risk of complications than oocyte donation alone. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Increasing compliance with a clinical practice guideline for fetal fibronectin testing and the management of threatened preterm labour: A quality improvement project
Conclusions A multi-faceted approach of audit and clinician feedback, interactive education and reminders supports the implementation of a clinical practice guideline for the use of fFN as a preterm birth prediction test for women presenting with symptoms of threatened preterm labour. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

FRAGILE X-ASSOCIATED PREMATURE OVARIAN FAILURE IN A LARGE TURKISH COHORT: Findings of Hacettepe Fragile X Registry
Conclusions FXPOI rates in the present cohort are higher than those reported in other populations. Higher FXPOI rates in Turkish premutation carriers might be a reflection of younger mean menopause age and higher POI rates in otherwise healthy Turkish women. Since POI is much more frequent among premutation carriers than in general population, testing for CGG repeat expansions in FMR1 should be included in the work-up. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Comparison of outcomes between induction of labor and spontaneous labor for term breech – A systemic review and meta analysis
Conclusions Induction of breech labor has higher cesarean section rate and NICU perinatal morbidity compared to spontaneous breech labor. The neonatal outcomes were otherwise similar across both groups. Eligibility for induction of breech labor needs to be assessed carefully according to individual situation. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Common errors made in attempt to contract the pelvic floor muscles in women early after delivery: A prospective observational study
Conclusion COMMOV are common errors performed during attempts to contract the pelvic floor muscles after delivery. They can reduce the ability to contract the pelvic floor muscles, but can easily been unlearned with visual observation and verbal feedback. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Reproducibility of the transvaginal sonographic assessment of bladder wall thickness
Conclusion The high levels of measurement error for a small measurement of BWT means it is unlikely Transvaginal ultrasound measurements have insufficient reliability and reproducibility to be an accurate diagnostic test. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Dutch women ’s attitudes towards hysterectomy and uterus preservation in surgical treatment of pelvic organ prolapse
Conclusions This study demonstrated that women referred with prolapse complaints have a preference for uterus preservation in case outcomes after both interventions are expected to be equal. The majority of women expected that body image and sexual function would equally improve after both interventions. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Sacrocolpopexy with polyvinylidene fluoride mesh for pelvic organ prolapse: Mid term comparative outcomes with polypropylene mesh
Conclusions Our findings suggest that both meshes can be safely and effectively used with good anatomical outcomes. Interestingly, PVDF use was associated with significantly less storage symptoms and sexual dysfunction. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Urinary incontinence is strongly associated with depression in middle-aged and older Korean women: Data from the Korean longitudinal study of ageing
Conclusions Inadequately controlled and frequent UI is strongly associated with depression in middle-aged and older Korean women. The management of worsening UI may be of value as part of the assessment and management of depression. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

IVF outcome in azoospermic cancer survivors
Conclusions Post-chemotherapy azoospermia can be successfully treated with TESE and ICSI, and should be offered to azoospermic cancer survivors who did not cryopreserve sperm prior to their gonadotoxic treatments. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Vitamin D metabolic loci and vitamin D status in Black and White pregnant women
Conclusion We observed associations between VDR, GC, and CYP27B1 variants and maternal 25-hydroxyvitamin D concentration. Our results provide additional support for a possible role of genetic variation in vitamin D metabolism genes on vitamin D status during pregnancy. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Gestational diabetes –Predictors of response to treatment and obstetric outcome
Conclusions Maternal BMI appears to be the only parameter that is predictive of need for treatment with metformin/insulin and the modality of treatment does not have an effect on maternal and neonatal outcomes. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Serial hCG and progesterone levels to predict early pregnancy outcomes in pregnancies of uncertain viability: A prospective study
Conclusion Serial hCG levels alone permitted an early viability diagnosis within 48h for 41.1% of patients with PUV instead of 7 to 14days with TVS. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Prediction of miscarriage in women with viable intrauterine pregnancy —A systematic review and diagnostic accuracy meta-analysis
Publication date: January 2018 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 220 Author(s): Rekha N. Pillai, Justin C. Konje, Matthew Richardson, Douglas G. Tincello, Neelam Potdar Both ultrasound and biochemical markers either alone or in combination have been described in the literature for the prediction of miscarriage. We performed this systematic review and meta-analysis to determine the best combination of biochemical, ultrasound and demographic markers to predict miscarriage in women with viable intrauterine pregnancy. The electronic database search included Medline (19...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Mixed urinary incontinence: A prospective study on the effect of trans-obturator mid-urethral sling
Conclusion Our study demonstrates TOT surgery can be performed for patients with MUI following unsuccessful conservative therapy. We also demonstrate that menopause and age >60 are risk factors for failure. This should be considered when counselling preoperatively. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

An ART score to note objectively the quality of an ART procedure
Conclusion An objective ART score has been constructed and validated. It will be of help to ART teams and it is an objective tool to explain to a couple the choices for the next ART attempt. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Thoracoamniotic shunting for fetal pleural effusion with hydropic change using a double-basket catheter: An insight into the preoperative determinants of shunting efficacy
Conclusions We achieved a high survival rate (75%) using the double-basket technique. A greater pretherapeutic width of skin edema compared with the pleural-effusion pocket is possibly suggestive of a treatment-resistant condition and subsequent poor postnatal outcome. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Factors that influence patient preference for mode of delivery following an obstetric anal sphincter injury
Conclusion Women with 3c/4th OASI are more likely to accept a planned CS. Bowel symptoms appear to have little impact on this but in women with lower grade tears sexual symptoms have the greatest impact on preferred MoD. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Subcutaneous trastuzumab (Herceptin) versus intravenous trastuzumab for the treatment of patients with HER2-positive breast cancer: A time, motion and cost assessment study in a lean operating day care oncology unit
Conclusion SC administration of trastuzumab was associated with a substantial reduction in active HCP time, patient chair time, unit time, and overall cost. These time and cost could be used to increase capacity within existing resources in a lean operating day dare oncology unit. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Prenatal detection of trisomy 8 mosaicism: Pregnancy outcome and follow up of a series of 17 consecutive cases
Conclusion Our data showed an overall positive prognosis for cases with an apparent confined placental mosaicism and those with low-level mosaicism in amniotic fluid if no congenital anomalies were detected by foetal ultrasound examinations. However, larger studies are warranted to better define the associated risk of neurodevelopmental anomalies. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

The impact of histological subtype in developing both ovarian and endometrial cancer: A longstanding nationwide incidence study
Conclusion Strong relationships exist between malignancies in the ovary and a second primary malignancy in the endometrium, especially for the endometrioid subtype of ovarian cancer. Viewed from the endometrial site, no special subtype was noted, and the influence of endometrial serous adenocarcinoma in developing serous OC is not plausible. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Maternal human chorionic gonadotrophin concentrations in very early pregnancy and risk of hyperemesis gravidarum: A retrospective cohort study of 4372 pregnancies after in vitro fertilization
Conclusions We found no association of maternal hCG concentrations on a fixed day in early pregnancy with development of hyperemesis gravidarum. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

High proportion of abnormal pap smear tests and cervical dysplasia in women with cystic fibrosis
Conclusion A high proportion of transplanted and non-transplanted women with CF had abnormal pap smear tests and cervical dysplasia. A regular gynaecological follow-up, periodic cervical screening, and routine HPV vaccination are strongly recommended in this population. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

Development and evaluation of an improved laparoscopic myomectomy adopting intracapsular rotary-cut procedures
Conclusions Our study provided strong supportive evidences showing that Intracapsular Rotary-cut Procedures is safe and practicable. The less uterine incision length, less surgery time, and less bleeding than the normal LM procedures all suggests that IRCP should be adopted in LM for facilitation to the operation procedures, minimization of operative invasiveness, and protection to patients’ infertility. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

p27kip1 as a key regulator of endometriosis
Publication date: February 2018 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 221 Author(s): G.A. Gonçalves p27kip1 as a key regulator of endometriosis Gonçalves GA p27kip1 is a cyclin-dependent kinase (CDK) inhibitor whose specific late G1 destruction allows progression of the cell across the G1/S boundary. There is a direct relationship between low level of p27 and rapid proliferation occurring in several benign states and in many malignances. In the glandular cells of the normal endometrium, the level of p27kip1 is exceedingly low during the proliferative phas...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2017 Category: OBGYN Source Type: research

The effect of follicullar fluid pesticides and polychlorinated biphenyls concentrations on intracytoplasmic sperm injection (ICSI) embryological and clinical outcome
Conclusion Higher concentrations of any studied PCBs and pesticides are associated with thinner endometrial thickness. The higher the level of Pretilachlor, β-cyfluthrin, PCB 28 and 180, the lower the retrieval, fertilization, and embryo cleavage rates. High PCB and pesticide concentrations in the FF adversely affected embryological ICSI outcomes. However, more data are needed to evaluate their effect on the clinical outcome. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 18, 2017 Category: OBGYN Source Type: research

Designing a lifestyle intervention to reduce risk of type 2 diabetes in postpartum mothers following gestational diabetes: An online survey with mothers and health professionals
Conclusion A walking programme, recipe ideas and weight monitoring may be useful components when designing a postpartum lifestyle intervention. Barriers to engagement are evident and the intervention should allow women to engage at a time that is appropriate for them. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 15, 2017 Category: OBGYN Source Type: research

A twelve –year retrospective analysis of prevalence and antimicrobial susceptibility patterns of Ureaplasma spp. and Mycoplasma hominis in the province of Lower Silesia in Poland.
Conclusion In the study Ureaplasma spp. and M. hominis were detected with relatively low frequency in comparison with other studies however, most of these isolates were resistant to ciprofloxacin indicating the need for better management of ciprofloxacin prescription. Important limitations of Mycoplasma IST2 assay concerning antimicrobial susceptibility testing and divergences between breakpoints in the test and EUCAST guidelines point the need to introduce new methodologies to improve evaluation of resistant strains at our region. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 15, 2017 Category: OBGYN Source Type: research

What gynaecologists need to master: Consensus on medical expertise outcome of pan-European postgraduate training in obstetrics and gynecology
Publication date: Available online 13 November 2017 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Charles Redman, Ulrich Petry, Simon Leeson, Pekka Niemenen, Xavier Carcopino, Christine Bergeron, Olaf Reich (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 14, 2017 Category: OBGYN Source Type: research

Dermatoglyphic patterns on fingers and gynecological cancers
Conclusion Our results showed that there is an association between fingerprint patterns and gynecological cancers and so, dermatoglyphic analysis may aid in the early diagnosis of these cancers. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 10, 2017 Category: OBGYN Source Type: research

Increased human Chorionic Gonadotropin levels five years before diagnosis of an ovarian dysgerminoma
Publication date: Available online 10 November 2017 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Gennaro Cormio, Michael J. Seckl, Vera Loizzi, Leonardo Resta, Ettore Cicinelli (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 10, 2017 Category: OBGYN Source Type: research

Improving communication at handover and transfer reduces retained swabs in maternity services
Conclusions Simple interventions to improve communication at handover and transfer can reduce the incidence of retained vaginal swabs and near misses. Further work is needed to raise the profile of swab counting in maternity settings: swab counting needs to be the responsibility of all disciplines, not just the responsibility of theatre staff. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 9, 2017 Category: OBGYN Source Type: research

Placental hypoxia inducible factor -1 α & amp; CHOP immuno-histochemical expression relative to maternal circulatory syncytiotrophoblast micro-vesicles in preeclamptic and normotensive pregnancies
Conclusion This study demonstrates increased placental expression of HIF-1α and CHOP in preeclampsia compared to normotensive pregnancies which correlate to their increased syncytiotrophoblast microvesicles concentration in maternal circulation. These findings indicate that placental hypoxia and ER stress are interrelated contributory factors to the pathogenesis of PE and the consequential release of placental derived debris into the maternal circulation. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 9, 2017 Category: OBGYN Source Type: research

Placental Hypoxia Inducible factor −1α & amp; CHOP Immuno-histochemical expression Relative to Maternal Circulatory Syncytiotrophoblast Micro-vesicles in Preeclamptic and Normotensive Pregnancies
Conclusion This study demonstrates increased placental expression of HIF-1α and CHOP in preeclampsia compared to normotensive pregnancies which correlate to their increased syncytiotrophoblast microvesicles concentration in maternal circulation. These findings indicate that placental hypoxia and ER stress are interrelated contributory factors to the pathogenesis of PE and the consequential release of placental derived debris into the maternal circulation. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 8, 2017 Category: OBGYN Source Type: research

ASSESSING THE RISK OF LAPAROSCOPIC MORCELLATION OF OCCULT UTERINE SARCOMAS DURING HYSTERECTOMY AND MYOMECTOMY: literature review and the ISGE recommendations
Conclusion Electromechanical tissue morcellation may be used in gynecological patients who are considered “low risk” upon appropriate preoperative evaluation; however, further studies and prospective data collection are greatly needed to improve sarcoma risk assessment in women with presumed uterine leiomyomas. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 7, 2017 Category: OBGYN Source Type: research

Prediction of miscarriage in women with viable intrauterine pregnancy- a systematic review and diagnostic accuracy meta-analysis
Publication date: Available online 4 November 2017 Source:European Journal of Obstetrics & Gynecology and Reproductive Biology Author(s): Rekha N. Pillai, Justin C. Konje, Matthew Richardson, Douglas G. Tincello, Neelam Potdar Both ultrasound and biochemical markers either alone or in combination have been described in the literature for the prediction of miscarriage. We performed this systematic review and meta-analysis to determine the best combination of biochemical, ultrasound and demographic markers to predict miscarriage in women with viable intrauterine pregnancy. The electronic database search included Med...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 5, 2017 Category: OBGYN Source Type: research

The “vanishing follicle” in women with low number of developing follicles during assisted reproduction
Conclusions The “vanishing follicle” phenomenon occasionally occurs in women with low number of developing follicles during assisted reproduction with no signs of ovulation. Our preliminary findings suggest that this phenomenon may be related to exhausted ovarian reserve however, an early-unrecognized LH elevation could not be ruled out. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - November 4, 2017 Category: OBGYN Source Type: research