Enhanced production of d-pantothenic acid in Corynebacterium glutamicum using an efficient CRISPR –Cpf1 genome editing method
Corynebacterium glutamicum has industrial track records for producing a variety of valuable products such as amino acids. Although CRISPR-based genome editing technologies have undergone immense developments in r... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - January 6, 2023 Category: Microbiology Authors: Rui Su, Ting Wang, Taidong Bo, Ningyun Cai, Meng Yuan, Chen Wu, Hao Jiang, Huadong Peng, Ning Chen and Yanjun Li Tags: Research Source Type: research
Serum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer
Conclusions: These results suggest that serum organic acid metabolites can be used as biomarkers to differentiate prostatitis, BPH, and PCa. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - January 4, 2023 Category: Allergy & Immunology Source Type: research
Sodium Multivitamin Transporter-Targeted Fluorochrome Facilitates Enhanced Metabolic Evaluation of Tumors Through Coenzyme-R Dependent Intracellular Signaling Pathways
ConclusionThese findings suggest that a SMVT-targeted NIR contrast agent can be a suitable tracer for imaging a wide range of malignancies as well as evaluating metabolic response to systemic therapies, similar to PET imaging with immune checkpoint inhibitors. (Source: Molecular Imaging and Biology)
Source: Molecular Imaging and Biology - December 19, 2022 Category: Molecular Biology Source Type: research
Cross-kingdom vitamin B5 biosynthesis and cyst nematode susceptibility
Trends Parasitol. 2022 Nov 25:S1471-4922(22)00277-X. doi: 10.1016/j.pt.2022.11.004. Online ahead of print.ABSTRACTVitamin deficiencies are known to cause disorders in human beings. Siddique et al. discovered that vitamin B5 biosynthesis in cyst nematodes requires steps in their host plants. Disruption of an Arabidopsis thaliana 'susceptibility gene', which is involved in the production of vitamin B5 precursors, results in reduced parasitism.PMID:36443162 | DOI:10.1016/j.pt.2022.11.004 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 28, 2022 Category: Parasitology Authors: Min Li Baodian Guo Fengquan Liu Zheng Qing Fu Source Type: research
Cross-kingdom vitamin B5 biosynthesis and cyst nematode susceptibility
Trends Parasitol. 2022 Nov 25:S1471-4922(22)00277-X. doi: 10.1016/j.pt.2022.11.004. Online ahead of print.ABSTRACTVitamin deficiencies are known to cause disorders in human beings. Siddique et al. discovered that vitamin B5 biosynthesis in cyst nematodes requires steps in their host plants. Disruption of an Arabidopsis thaliana 'susceptibility gene', which is involved in the production of vitamin B5 precursors, results in reduced parasitism.PMID:36443162 | DOI:10.1016/j.pt.2022.11.004 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 28, 2022 Category: Parasitology Authors: Min Li Baodian Guo Fengquan Liu Zheng Qing Fu Source Type: research
Cross-kingdom vitamin B5 biosynthesis and cyst nematode susceptibility
Trends Parasitol. 2022 Nov 25:S1471-4922(22)00277-X. doi: 10.1016/j.pt.2022.11.004. Online ahead of print.NO ABSTRACTPMID:36443162 | DOI:10.1016/j.pt.2022.11.004 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 28, 2022 Category: Parasitology Authors: Min Li Baodian Guo Fengquan Liu Zheng Qing Fu Source Type: research
Cross-kingdom vitamin B5 biosynthesis and cyst nematode susceptibility
Trends Parasitol. 2022 Nov 25:S1471-4922(22)00277-X. doi: 10.1016/j.pt.2022.11.004. Online ahead of print.NO ABSTRACTPMID:36443162 | DOI:10.1016/j.pt.2022.11.004 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 28, 2022 Category: Parasitology Authors: Min Li Baodian Guo Fengquan Liu Zheng Qing Fu Source Type: research
Cross-kingdom vitamin B5 biosynthesis and cyst nematode susceptibility
Trends Parasitol. 2022 Nov 25:S1471-4922(22)00277-X. doi: 10.1016/j.pt.2022.11.004. Online ahead of print.NO ABSTRACTPMID:36443162 | DOI:10.1016/j.pt.2022.11.004 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 28, 2022 Category: Parasitology Authors: Min Li Baodian Guo Fengquan Liu Zheng Qing Fu Source Type: research
Cross-kingdom vitamin B5 biosynthesis and cyst nematode susceptibility
Trends Parasitol. 2022 Nov 25:S1471-4922(22)00277-X. doi: 10.1016/j.pt.2022.11.004. Online ahead of print.NO ABSTRACTPMID:36443162 | DOI:10.1016/j.pt.2022.11.004 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 28, 2022 Category: Parasitology Authors: Min Li Baodian Guo Fengquan Liu Zheng Qing Fu Source Type: research
The association between B vitamins and the risk of COVID-19
This study was undertaken on 9189 adult participants of the Yazd Health Study (YaHS) and Taghzieh Mardom-e-Yazd (TAMIZ) study aged 20 to 69 years. Data on dietary intakes were obtained using a validated food frequency questionnaire (FFQ). Multivariable logistic regression analysis was used to evaluate the association between B vitamins and COVID-19. Our findings indicated that participants in the fourth quartile of vitamin B5 intake compared to the first quartile had a protective effect against COVID-19 (OR: 0. 53 CI: 0.28- 0.99, p- trend =0.02) after adjustment for all possible confounds in model 3. In addition, participa...
Source: The British Journal of Nutrition - November 9, 2022 Category: Nutrition Authors: Mina Darand Shirin Hassanizadeh Fahime Martami Shamim Shams-Rad Masoud Mirzaei Mahdieh Hosseinzadeh Source Type: research
The association between B vitamins and the risk of COVID-19
This study was undertaken on 9189 adult participants of the Yazd Health Study (YaHS) and Taghzieh Mardom-e-Yazd (TAMIZ) study aged 20 to 69 years. Data on dietary intakes were obtained using a validated food frequency questionnaire (FFQ). Multivariable logistic regression analysis was used to evaluate the association between B vitamins and COVID-19. Our findings indicated that participants in the fourth quartile of vitamin B5 intake compared to the first quartile had a protective effect against COVID-19 (OR: 0. 53 CI: 0.28- 0.99, p- trend =0.02) after adjustment for all possible confounds in model 3. In addition, participa...
Source: The British Journal of Nutrition - November 9, 2022 Category: Nutrition Authors: Mina Darand Shirin Hassanizadeh Fahime Martami Shamim Shams-Rad Masoud Mirzaei Mahdieh Hosseinzadeh Source Type: research
Ultrasonic ‑assisted molten salt hydrates pretreated Eucheuma cottonii residues as a greener precursor for third-generation L-lactic acid production
This study aims to establish an efficient pretreatment method that facilitates the conversion of sugars from macroalgae wastes, Eucheuma cottonii residues (ECRs) during hydrolysis and subsequently enhances L-lactic acid (L-LA) production. Hence, ultrasonic-assisted molten salt hydrates (UMSHs) pretreatment was proposed to enhance the accessibility of ECRs to hydrolyze into glucose through dilute acid hydrolysis (DAH). The obtained hydrolysates were employed as the substrate in producing L-LA by separate hydrolysis and fermentation (SHF). The maximum glucose yield (97.75%) was achieved using UMSHs pretreated ECRs with 40wt%...
Source: Bioresource Technology - October 18, 2022 Category: Biotechnology Authors: Soo Ling Chong Inn Shi Tan Henry Chee Yew Foo Yen San Chan Man Kee Lam Keat Teong Lee Source Type: research
Ultrasonic ‑assisted molten salt hydrates pretreated Eucheuma cottonii residues as a greener precursor for third-generation L-lactic acid production
This study aims to establish an efficient pretreatment method that facilitates the conversion of sugars from macroalgae wastes, Eucheuma cottonii residues (ECRs) during hydrolysis and subsequently enhances L-lactic acid (L-LA) production. Hence, ultrasonic-assisted molten salt hydrates (UMSHs) pretreatment was proposed to enhance the accessibility of ECRs to hydrolyze into glucose through dilute acid hydrolysis (DAH). The obtained hydrolysates were employed as the substrate in producing L-LA by separate hydrolysis and fermentation (SHF). The maximum glucose yield (97.75%) was achieved using UMSHs pretreated ECRs with 40wt%...
Source: Bioresource Technology - October 18, 2022 Category: Biotechnology Authors: Soo Ling Chong Inn Shi Tan Henry Chee Yew Foo Yen San Chan Man Kee Lam Keat Teong Lee Source Type: research
