Metabolomic differentiation of tumor core versus edge in glioma
CONCLUSIONS: Key metabolic differences are identified between core and edge tissue in glioma and, furthermore, demonstrate the potential for machine learning to provide insight into potential prognostic and therapeutic targets.PMID:37283447 | DOI:10.3171/2023.3.FOCUS2379 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - June 7, 2023 Category: Neurosurgery Authors: Mary E Baxter Hunter A Miller Joseph Chen Brian J Williams Hermann B Frieboes Source Type: research
Metabolomic differentiation of tumor core versus edge in glioma
CONCLUSIONS: Key metabolic differences are identified between core and edge tissue in glioma and, furthermore, demonstrate the potential for machine learning to provide insight into potential prognostic and therapeutic targets.PMID:37283447 | DOI:10.3171/2023.3.FOCUS2379 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - June 7, 2023 Category: Neurosurgery Authors: Mary E Baxter Hunter A Miller Joseph Chen Brian J Williams Hermann B Frieboes Source Type: research
Metabolomic differentiation of tumor core versus edge in glioma
CONCLUSIONS: Key metabolic differences are identified between core and edge tissue in glioma and, furthermore, demonstrate the potential for machine learning to provide insight into potential prognostic and therapeutic targets.PMID:37283447 | DOI:10.3171/2023.3.FOCUS2379 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - June 7, 2023 Category: Neurosurgery Authors: Mary E Baxter Hunter A Miller Joseph Chen Brian J Williams Hermann B Frieboes Source Type: research
Metabolomic differentiation of tumor core versus edge in glioma
CONCLUSIONS: Key metabolic differences are identified between core and edge tissue in glioma and, furthermore, demonstrate the potential for machine learning to provide insight into potential prognostic and therapeutic targets.PMID:37283447 | DOI:10.3171/2023.3.FOCUS2379 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - June 7, 2023 Category: Neurosurgery Authors: Mary E Baxter Hunter A Miller Joseph Chen Brian J Williams Hermann B Frieboes Source Type: research
Metabolomic differentiation of tumor core versus edge in glioma
CONCLUSIONS: Key metabolic differences are identified between core and edge tissue in glioma and, furthermore, demonstrate the potential for machine learning to provide insight into potential prognostic and therapeutic targets.PMID:37283447 | DOI:10.3171/2023.3.FOCUS2379 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - June 7, 2023 Category: Neurosurgery Authors: Mary E Baxter Hunter A Miller Joseph Chen Brian J Williams Hermann B Frieboes Source Type: research
Metabolomic differentiation of tumor core versus edge in glioma
CONCLUSIONS: Key metabolic differences are identified between core and edge tissue in glioma and, furthermore, demonstrate the potential for machine learning to provide insight into potential prognostic and therapeutic targets.PMID:37283447 | DOI:10.3171/2023.3.FOCUS2379 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - June 7, 2023 Category: Neurosurgery Authors: Mary E Baxter Hunter A Miller Joseph Chen Brian J Williams Hermann B Frieboes Source Type: research
Dexpanthenol protects against lipopolysaccharide-induced acute kidney injury by restoring AQP-2 levels via regulating SIRT-1 signaling pathway
CONCLUSIONS: In conclusion, DEX was found to be effective in preventing inflammation, oxidative stress, and apoptosis in the kidney through the SIRT1 signaling pathway. Thus, the protective properties of DEX suggest that it may be a potential therapeutic agent for kidney pathologies.PMID:37232072 | DOI:10.4097/kja.23207 (Source: Korean Journal of Anesthesiology)
Source: Korean Journal of Anesthesiology - May 26, 2023 Category: Anesthesiology Authors: Eyyup S Ozden Halil Asci Halil I Buyukbayram Mehmet A Sevuk Orhan B Imeci Hatice K Dogan Ozlem Ozmen Source Type: research
Potential of algae-derived alginate oligosaccharides and β-glucan to counter inflammation in adult zebrafish intestine
Alginate oligosaccharides (AOS) are natural bioactive compounds with anti-inflammatory properties. We performed a feeding trial employing a zebrafish (Danio rerio) model of soybean-induced intestinal inflammation. Five groups of fish were fed different diets: a control (CT) diet, a soybean meal (SBM) diet, a soybean meal+β-glucan (BG) diet and 2 soybean meal+AOS diets (alginate products differing in the content of low molecular weight fractions - AL, with 31% < 3kDa and AH, with 3% < 3kDa). We analyzed the intestinal transcriptomic and plasma metabolomic profiles of the study groups. In addition, we assessed the exp...
Source: Frontiers in Immunology - May 19, 2023 Category: Allergy & Immunology Source Type: research
A Non-targeted Metabolomics Reveals Therapeutical Effect and Mechanism of Sanmiao Pill on Adjuvant-induced Arthritis Rats
Conclusion: These results indicated that RA-related biomarkers reflected the metabolic profile of AIA rats. Meanwhile, SMP could effectively treat RA mainly by reducing inflammation and regulating abnormal lipid metabolic pathways and amino acid metabolisms. It showed that metabolomics could be used to analyze the metabolic profiles involved in RA and reveal the mechanism of SMP treatment of RA.PMID:37171005 | DOI:10.2174/1381612829666230511161308 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - May 12, 2023 Category: Drugs & Pharmacology Authors: Dongdong Cao Le Yang Xin Gao Danna Huang Xiaoning Zhan Shi Qiu Hui Sun Guangli Yan Xijun Wang Source Type: research
A Non-targeted Metabolomics Reveals Therapeutical Effect and Mechanism of Sanmiao Pill on Adjuvant-induced Arthritis Rats
Conclusion: These results indicated that RA-related biomarkers reflected the metabolic profile of AIA rats. Meanwhile, SMP could effectively treat RA mainly by reducing inflammation and regulating abnormal lipid metabolic pathways and amino acid metabolisms. It showed that metabolomics could be used to analyze the metabolic profiles involved in RA and reveal the mechanism of SMP treatment of RA.PMID:37171005 | DOI:10.2174/1381612829666230511161308 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - May 12, 2023 Category: Drugs & Pharmacology Authors: Dongdong Cao Le Yang Xin Gao Danna Huang Xiaoning Zhan Shi Qiu Hui Sun Guangli Yan Xijun Wang Source Type: research
