Clinical benefits of novel non ‐nucleoside reverse transcriptase inhibitors: A prospective cohort study
ConclusionsBoth regimens showed good virological effectiveness; however, compared with ANV+3TC+TDF, the EFV+3TC+TDF regimen reduced the prevalence of HIV-related symptoms. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 5, 2024 Category: Allergy & Immunology Authors: Shujing Ma,
Xiaoxin Xie,
Yanhua Fu,
Lin Gan,
Xiaoyan Yang,
Linghong Kong,
Jun Li,
Hai Long Tags: ORIGINAL ARTICLE Source Type: research
Relative Bioavailability of Dolutegravir (DTG) and Emtricitabine/Tenofovir Alafenamide Fumarate (F/TAF) Administered as Paediatric Tablet Formulations in Healthy Volunteers
ConclusionsAlthough TAF AUC andCmax 90% CIs fell outside the pre-defined criteria (0.62 –1.11 and 0.65–1.01, respectively), no consistent effect on TAF PK was observed, likely due to high inter-subject variability. Moreover, there are several reasons to rely on TFV exposure as being more clinically relevant than TAF exposure. Therefore, we found no clinically relevant interactions in this study. (Source: Clinical Pharmacokinetics)
Source: Clinical Pharmacokinetics - April 4, 2024 Category: Drugs & Pharmacology Source Type: research
Hepatitis B relapse after entecavir or tenofovir alafenamide cessation under anti-viral prophylaxis for cancer chemotherapy
No study has comparing hepatitis B virus (HBV) relapse rates among patients with both cancer and hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) who completed anti-viral prophylaxis for chemot... (Source: Virology Journal)
Source: Virology Journal - April 3, 2024 Category: Virology Authors: Hsin-Wei Fang, Po-Lin Tseng, Tsung-Hui Hu, Jing-Houng Wang, Chao-Hung Hung, Sheng-Nan Lu and Chien-Hung Chen Tags: Research Source Type: research
Comparison of the Effects of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Liver Function in Patients with Hepatitis B: A Meta-analysis
CONCLUSIONS: Both TAF and TDF are effective in the treatment of CHB, but the former is preferred due to its higher safety profile.PMID:38551440 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Longda Chen Qingqing Jiang Xun Chen Source Type: research
Comparison of the Effects of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Liver Function in Patients with Hepatitis B: A Meta-analysis
CONCLUSIONS: Both TAF and TDF are effective in the treatment of CHB, but the former is preferred due to its higher safety profile.PMID:38551440 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Longda Chen Qingqing Jiang Xun Chen Source Type: research
Comparison of the Effects of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Liver Function in Patients with Hepatitis B: A Meta-analysis
CONCLUSIONS: Both TAF and TDF are effective in the treatment of CHB, but the former is preferred due to its higher safety profile.PMID:38551440 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Longda Chen Qingqing Jiang Xun Chen Source Type: research
Comparison of the Effects of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Liver Function in Patients with Hepatitis B: A Meta-analysis
CONCLUSIONS: Both TAF and TDF are effective in the treatment of CHB, but the former is preferred due to its higher safety profile.PMID:38551440 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Longda Chen Qingqing Jiang Xun Chen Source Type: research
Comparison of the Effects of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Liver Function in Patients with Hepatitis B: A Meta-analysis
CONCLUSIONS: Both TAF and TDF are effective in the treatment of CHB, but the former is preferred due to its higher safety profile.PMID:38551440 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Longda Chen Qingqing Jiang Xun Chen Source Type: research
Comparison of the Effects of Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Liver Function in Patients with Hepatitis B: A Meta-analysis
CONCLUSIONS: Both TAF and TDF are effective in the treatment of CHB, but the former is preferred due to its higher safety profile.PMID:38551440 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 29, 2024 Category: Complementary Medicine Authors: Longda Chen Qingqing Jiang Xun Chen Source Type: research
Cardiometabolic Risk Profiles of Adolescents Living With Perinatally Acquired HIV in South Africa
CONCLUSIONS: Adolescents with perinatally acquired HIV appear at risk for cardiovascular disease. Specific tools for monitoring this risk are needed to institute appropriate preventive interventions.PMID:38535131 | DOI:10.1097/INF.0000000000004340 (Source: Atherosclerosis)
Source: Atherosclerosis - March 27, 2024 Category: Cardiology Authors: Leonore Greybe Shaun Barnabas Mark Cotton Penelope Rose Helena Rabie Lisa Frigati Source Type: research
Cardiometabolic Risk Profiles of Adolescents Living With Perinatally Acquired HIV in South Africa
CONCLUSIONS: Adolescents with perinatally acquired HIV appear at risk for cardiovascular disease. Specific tools for monitoring this risk are needed to institute appropriate preventive interventions.PMID:38535131 | DOI:10.1097/INF.0000000000004340 (Source: Atherosclerosis)
Source: Atherosclerosis - March 27, 2024 Category: Cardiology Authors: Leonore Greybe Shaun Barnabas Mark Cotton Penelope Rose Helena Rabie Lisa Frigati Source Type: research
Project CHARIOT: study protocol for a hybrid type 1 effectiveness-implementation study of comprehensive tele-harm reduction for engagement of people who inject drugs in HIV prevention services
The objectives are: (1) to determine if the C-THR intervention increases engagement in HIV prevention (i.e., HIV pre-exposure prophylaxis; PrEP or medications for opioid use disorder; MOUD) compared to non-SSP clinic referral and patient navigation, (2) to examine the long-term effectiveness and cost-effectiveness of the C-THR intervention, and (3) to assess the barriers and facilitators to implementation and sustainment of the C-THR intervention. The co-primary outcomes are PrEP or MOUD engagement across follow-up at 3, 6, 9 and 12 months. For PrEP, engagement is confirmed by tenofovir on dried blood spot or cabotegravir ...
Source: Addiction Science and Clinical Practice - March 26, 2024 Category: Addiction Authors: Tyler S Bartholomew Marina Plesons David P Serota Elizabeth Alonso Lisa R Metsch Daniel J Feaster Jessica Ucha Edward Suarez David W Forrest Teresa A Chueng Katrina Ciraldo Jimmie Brooks Justin D Smith Joshua A Barocas Hansel E Tookes Source Type: research
Project CHARIOT: study protocol for a hybrid type 1 effectiveness-implementation study of comprehensive tele-harm reduction for engagement of people who inject drugs in HIV prevention services
The objectives are: (1) to determine if the C-THR intervention increases engagement in HIV prevention (i.e., HIV pre-exposure prophylaxis; PrEP or medications for opioid use disorder; MOUD) compared to non-SSP clinic referral and patient navigation, (2) to examine the long-term effectiveness and cost-effectiveness of the C-THR intervention, and (3) to assess the barriers and facilitators to implementation and sustainment of the C-THR intervention. The co-primary outcomes are PrEP or MOUD engagement across follow-up at 3, 6, 9 and 12 months. For PrEP, engagement is confirmed by tenofovir on dried blood spot or cabotegravir ...
Source: Addiction Science and Clinical Practice - March 26, 2024 Category: Addiction Authors: Tyler S Bartholomew Marina Plesons David P Serota Elizabeth Alonso Lisa R Metsch Daniel J Feaster Jessica Ucha Edward Suarez David W Forrest Teresa A Chueng Katrina Ciraldo Jimmie Brooks Justin D Smith Joshua A Barocas Hansel E Tookes Source Type: research
Project CHARIOT: study protocol for a hybrid type 1 effectiveness-implementation study of comprehensive tele-harm reduction for engagement of people who inject drugs in HIV prevention services
The objectives are: (1) to determine if the C-THR intervention increases engagement in HIV prevention (i.e., HIV pre-exposure prophylaxis; PrEP or medications for opioid use disorder; MOUD) compared to non-SSP clinic referral and patient navigation, (2) to examine the long-term effectiveness and cost-effectiveness of the C-THR intervention, and (3) to assess the barriers and facilitators to implementation and sustainment of the C-THR intervention. The co-primary outcomes are PrEP or MOUD engagement across follow-up at 3, 6, 9 and 12 months. For PrEP, engagement is confirmed by tenofovir on dried blood spot or cabotegravir ...
Source: Addiction Science and Clinical Practice - March 26, 2024 Category: Addiction Authors: Tyler S Bartholomew Marina Plesons David P Serota Elizabeth Alonso Lisa R Metsch Daniel J Feaster Jessica Ucha Edward Suarez David W Forrest Teresa A Chueng Katrina Ciraldo Jimmie Brooks Justin D Smith Joshua A Barocas Hansel E Tookes Source Type: research
