Stimulation of microvesicle secretion in Trichomonas vaginalis
Exp Parasitol. 2024 Feb 21;259:108722. doi: 10.1016/j.exppara.2024.108722. Online ahead of print.ABSTRACTTrichomonas vaginalis is an extracellular flagellate protozoan and the etiological agent of human trichomoniasis, a sexually transmitted infection (STI) with a high incidence. Several reports have shown that this protozoan releases microvesicles into the culture medium, which show high potential in modulating cell-to-cell communication and the host response to infections. However, the biogenesis of these vesicles has not been analyzed in detail. In the present study, high-resolution ion scanning microscopy (SEM) and tra...
Source: Experimental Parasitology - February 23, 2024 Category: Parasitology Authors: J úlio César Santana de Andrade Marlene Benchimol Wanderley de Souza Source Type: research
Stimulation of microvesicle secretion in Trichomonas vaginalis
Exp Parasitol. 2024 Feb 21;259:108722. doi: 10.1016/j.exppara.2024.108722. Online ahead of print.ABSTRACTTrichomonas vaginalis is an extracellular flagellate protozoan and the etiological agent of human trichomoniasis, a sexually transmitted infection (STI) with a high incidence. Several reports have shown that this protozoan releases microvesicles into the culture medium, which show high potential in modulating cell-to-cell communication and the host response to infections. However, the biogenesis of these vesicles has not been analyzed in detail. In the present study, high-resolution ion scanning microscopy (SEM) and tra...
Source: Experimental Parasitology - February 23, 2024 Category: Parasitology Authors: J úlio César Santana de Andrade Marlene Benchimol Wanderley de Souza Source Type: research
Establishment and application of a rapid molecular diagnostic platform for the isothermal visual amplification of group B Streptococcus based on recombinase polymerase
In conclusion, this study successfully established a combined RPA and LFS GBS in situ detection platform, with short reaction time, high sensitivity, high specificity, portability, and device independence, providing a feasible strategy for clinical GBS screening. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - February 23, 2024 Category: Microbiology Source Type: research
The core exosome proteome of Trichomonas vaginalis
CONCLUSIONS: Our study highlighted the importance of using supernatant fraction from exosomal extract as a control to eliminate 'non-core exosomal proteins'. We compiled a reference core exosome proteome of T. vaginalis, which is essential for developing a fundamental understanding of exosome-mediated cell communication and host-parasite interaction.PMID:38383245 | DOI:10.1016/j.jmii.2024.02.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2024 Category: Microbiology Authors: Seow-Chin Ong Hong-Wei Luo Wei-Hung Cheng Fu-Man Ku Chih-Yu Tsai Po-Jung Huang Chi-Ching Lee Yuan-Ming Yeh Rose Lin Cheng-Hsun Chiu Petrus Tang Source Type: research
The core exosome proteome of Trichomonas vaginalis
CONCLUSIONS: Our study highlighted the importance of using supernatant fraction from exosomal extract as a control to eliminate 'non-core exosomal proteins'. We compiled a reference core exosome proteome of T. vaginalis, which is essential for developing a fundamental understanding of exosome-mediated cell communication and host-parasite interaction.PMID:38383245 | DOI:10.1016/j.jmii.2024.02.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2024 Category: Microbiology Authors: Seow-Chin Ong Hong-Wei Luo Wei-Hung Cheng Fu-Man Ku Chih-Yu Tsai Po-Jung Huang Chi-Ching Lee Yuan-Ming Yeh Rose Lin Cheng-Hsun Chiu Petrus Tang Source Type: research
The core exosome proteome of Trichomonas vaginalis
CONCLUSIONS: Our study highlighted the importance of using supernatant fraction from exosomal extract as a control to eliminate 'non-core exosomal proteins'. We compiled a reference core exosome proteome of T. vaginalis, which is essential for developing a fundamental understanding of exosome-mediated cell communication and host-parasite interaction.PMID:38383245 | DOI:10.1016/j.jmii.2024.02.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2024 Category: Microbiology Authors: Seow-Chin Ong Hong-Wei Luo Wei-Hung Cheng Fu-Man Ku Chih-Yu Tsai Po-Jung Huang Chi-Ching Lee Yuan-Ming Yeh Rose Lin Cheng-Hsun Chiu Petrus Tang Source Type: research
Point-of-care testing for sexually transmitted infections and HIV pre-exposure prophylaxis among pregnant women in South Africa, 2021-2022: randomised controlled trial
Conclusions
POC STI testing was not associated with PrEP initiation or persistence relative to syndromic management. However, improving STI diagnosis by supplementing syndromic management with POC STI testing could improve PrEP initiation among PPW.
Trial registration number
NCT03902418; Clinical Trials.gov; 1 April 2019. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - February 19, 2024 Category: Sexual Medicine Authors: de Voux, A., Nyemba, D. C., Silliman, M., Mashele, N., Mvududu, R., Myer, L., Joseph Davey, D. Tags: Original research Source Type: research
Aetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study
CONCLUSION: This study provided the acquisition of unprecedented data on the aetiology of UDS and GUD in Brazil, demonstrated the presence of a variety of pathogens in both sample types and reaffirmed the aetiologies known to be most prevalent globally.PMID:38360847 | DOI:10.1136/sextrans-2023-055950 (Source: Herpes)
Source: Herpes - February 15, 2024 Category: Infectious Diseases Authors: Maria Luiza Bazzo Hanalydia de Melo Machado Jessica Motta Martins Marcos Andr é Schörner Ketlyn Buss Fernando Hartmann Barazzetti Pamela Cristina Gaspar Alisson Bigolin Adele Benzaken Simone Veloso Faria de Carvalho Lidiane da Fonseca Andrade William An Source Type: research
Clinical Utility and Evaluation of the Alinity m STI assay at a Large Academic Medical Center in the Southeastern United States
The objective of this study was to use the clinical utility of the Alinity m STI (CT/NG/TV/MG) assay and compare results to Hologic Aptima CT/NG and TV assays for STI testing at Tampa General Hospital. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 1, 2024 Category: OBGYN Authors: Kostera J, Cullum R Source Type: research
Feasibility of a 30-Minute Sample-to-Answer Chlamydia Trachomatis, Neisseria Gonorrhea, and Trichomonas Vaginalis Multiplex Test on a Rapid Molecular Point-of-Care System*
Determine the feasibility of a 30-minute test for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) from urine and vaginal swab samples on a rapid molecular point-of-care system. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 1, 2024 Category: OBGYN Authors: Nguyen B, Pryce M, Parker E, Liang J, Wei C, Crowley C, Green A, Wu B Source Type: research
Bacterial Vaginosis, Vaginal PH, and Sexually Transmitted Infections: Neisseria Gonorrhoeae, Chlamydia Trachomatis, Trichomonas Vaginalis
To determine the association between high vaginal pH, bacterial vaginosis (BV) diagnosed by Amsel ’s Criteria, and Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), and Trichomonas vaginalis (TV) in patients with vaginitis symptoms. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - February 1, 2024 Category: OBGYN Authors: McLaughlin S, Thibault C, Golden M Source Type: research
Clinical implications of trichomonads detected in bronchoalveolar fluid by metagenomic next-generation sequencing: a multicenter retrospective study
ConclusionmNGS proves to be an efficient tool for detecting trichomonads in BALF samples. Comprehensive analysis of clinical features and laboratory indicators is essential to distinguish between infection and colonization of trichomonads. Pulmonary trichomoniasis should not be overlooked when trichomonads are detected in BALF from patients with risk factors. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - January 22, 2024 Category: Microbiology Source Type: research
Declining Prevalence of Trichomonas vaginalis Diagnosed by Wet Mount in a Cohort of U.S. Women With and Without HIV
Journal of Women's Health, Ahead of Print. (Source: Journal of Women)
Source: Journal of Women - January 12, 2024 Category: OBGYN Authors: Elizabeth M. Daubert Jodie Dionne Jessica Atrio Andrea K. Knittel Seble G. Kassaye Dominika Seidman Amanda Long Susan Brockmann Igho Ofotokun Margaret A. Fischl L. Stewart Massad Kathleen M. Weber Source Type: research
A novel detection method based on MIRA-CRISPR/Cas13a-LFD targeting the repeated DNA sequence of Trichomonas vaginalis
Trichomonas vaginalis is a protozoan parasite, widely recognized as the most prevalent non-viral sexually transmitted infection (STI) globally. This infection is linked to various complications, including pelvic ... (Source: Parasites and Vectors)
Source: Parasites and Vectors - January 8, 2024 Category: Microbiology Authors: Zhenke Yang, Jinghui Wang, Yiming Qi, Yiping Shi, Fakun Li, Weijuan Wang, Xiaowei Tian, Xuefang Mei, Zhenchao Zhang and Shuai Wang Tags: Research Source Type: research
Sexually and non ‐sexually transmitted infections and the risk of prostate cancer: Results from the EPICAP study
ConclusionOur results showed that sexually or non-sexually transmitted infections, either bacterial or viral, were not associated to prostate cancer. Therefore, further investigation is needed to help advance our understanding of the role of chronic inflammation in the etiology of prostate cancer, with a particular focus on its most aggressive types. (Source: Cancer Medicine)
Source: Cancer Medicine - January 4, 2024 Category: Cancer & Oncology Authors: Melissa Sawaya,
Emilie Cordina ‐Duverger,
Pierre‐Jean Lamy,
Xavier Rébillard,
Brigitte Trétarre,
Florence Menegaux Tags: RESEARCH ARTICLE Source Type: research
