< em > Tribulus terrestris < /em > L. Extract Protects against Lipopolysaccharide-Induced Inflammation in RAW 264.7 Macrophage and Zebrafish via Inhibition of Akt/MAPKs and NF- < em > κ < /em > B/iNOS-NO Signaling Pathways
Evid Based Complement Alternat Med. 2021 Feb 12;2021:6628561. doi: 10.1155/2021/6628561. eCollection 2021.ABSTRACTInflammation response is a regulated cellular process and excessive inflammation has been recognized in numerous diseases, such as cardiovascular disease, neurodegenerative disease, inflammatory bowel disease, and cancer. Tribulus terrestris L. (TT), also known as Bai Jili in Chinese, has been applied in traditional Chinese medicine for thousands of years while its anti-inflammatory activity and underlying mechanism are not fully elucidated. Here, we hypothesize Tribulus terrestris L. extract (BJL) which prese...
Source: Evidence-based Complementary and Alternative Medicine - February 25, 2021 Category: Complementary Medicine Authors: Wai-Rong Zhao Wen-Ting Shi Jing Zhang Kai-Yu Zhang Ye Qing Jing-Yi Tang Xin-Lin Chen Zhong-Yan Zhou Source Type: research
Molecules, Vol. 26, Pages 408: Phytochemical and Biological Evaluation of a Newly Designed Nutraceutical Self-Nanoemulsifying Self-Nanosuspension for Protection and Treatment of Cisplatin Induced Testicular Toxicity in Male Rats
. Abdel-Monem
The incorporation of cisplatin (CP) as a cytotoxic antineoplastic agent in most chemotherapeutic protocols is a challenge due to its toxic effect on testicular tissues. Natural compounds present a promising trend in research, so a new nutraceutical formulation (NCF) was designed to diminish CP spermatotoxicity. A combination of three nutraceutical materials, 250 mg Spirulina platensis powder (SP), 25 mg Tribulus terrestris L. extract (TT), and 100 mg fish oil (FO) were formulated in self-nanoemulsifying self-nanosuspension (SNESNS). SP was loaded into the optimized self-nanoemulsifying system (30% FO, 50%...
Source: Molecules - January 14, 2021 Category: Chemistry Authors: Sherif R. Abdel-All Zeinab T. Abdel Shakour Dalia M. N. Abouhussein Enji Reda Thoraya F. Sallam Hala M. El-Hefnawy Azza R. Abdel-Monem Tags: Article Source Type: research
Tribulus terrestris and female reproductive system health: A comprehensive review
Publication date: Available online 8 January 2021Source: PhytomedicineAuthor(s): Ali Ghanbari, Nasim Akhshi, Seyed Ershad Nedaei, Adriano Mollica, Ina Yosifova Aneva, Yaping Qi, Pan Liao, Sara Darakhshan, Mohammad Hosein Farzaei, Jianbo Xiao, Javier Echeverría (Source: Phytomedicine)
Source: Phytomedicine - January 9, 2021 Category: Drugs & Pharmacology Source Type: research
Protective effects of Tribulus terrestris and Cinnamomum zeylanicum extracts and trehalose added to diluents on goat epididymal sperm freezability.
In conclusion, the results of this study indicate that 50 μg/ml of Tribulus terrestris and Cinnamomum zeylanicum ethanolic extracts alone and plus trehalose improved the spermatozoa quality and could be used for cryopreservation.
PMID: 33245877 [PubMed - as supplied by publisher] (Source: Cryobiology)
Source: Cryobiology - November 24, 2020 Category: Biology Authors: Ariyan F, Farshad A, Rostamzadeh J Tags: Cryobiology Source Type: research
Comparative Efficacy of Gum Arabic (Acacia senegal) and Tribulus terrestris on Male Fertility
Publication date: Available online 18 November 2020Source: Saudi Pharmaceutical JournalAuthor(s): Omaima Nasir, Nada Alqadri, Salma Elsayed, Omaima Ahmed, S.H. Alotaibi, Roua Baty, Hiba Omer, Suzan A. Abushal, Umbach AT (Source: Saudi Pharmaceutical Journal)
Source: Saudi Pharmaceutical Journal - November 18, 2020 Category: Drugs & Pharmacology Source Type: research
Adnexal mass: diagnosis and management
Conclusion MoreRCTs are needed to supportor refute the use of T. terrestris. The decision to use this intervention should be shared with the patients, and the uncertainties around its effects should be discussed in the clinical decision-making process. Number of Protocol registration in PROSPERO database: CRD42019121130Resumo Objetivo N ós realizamos uma revisão sistemática para avaliar a efetividade e a segurança do Tribulus terrestris no tratamento da disfunção sexual feminina (DSF). Fontes de dados Nós realizados uma busca eletrônica irrestrita nas seguintes bases de dados: MEDLINE, CENTRAL, EMBASE, LILACS,...
Source: Revista Brasileira de Ginecologia e Obstetricia - August 27, 2020 Category: OBGYN Source Type: research
Overuse of Diagnostic Tests in Clinical Practice: Are Gynecologists Aware of the Scientific Guidelines?
Conclusion MoreRCTs are needed to supportor refute the use of T. terrestris. The decision to use this intervention should be shared with the patients, and the uncertainties around its effects should be discussed in the clinical decision-making process. Number of Protocol registration in PROSPERO database: CRD42019121130Resumo Objetivo N ós realizamos uma revisão sistemática para avaliar a efetividade e a segurança do Tribulus terrestris no tratamento da disfunção sexual feminina (DSF). Fontes de dados Nós realizados uma busca eletrônica irrestrita nas seguintes bases de dados: MEDLINE, CENTRAL, EMBASE, LILACS,...
Source: Revista Brasileira de Ginecologia e Obstetricia - August 27, 2020 Category: OBGYN Source Type: research
Tribulus Terrestris for Female Sexual Dysfunction: A Systematic Review
Conclusion MoreRCTs are needed to supportor refute the use of T. terrestris. The decision to use this intervention should be shared with the patients, and the uncertainties around its effects should be discussed in the clinical decision-making process. Number of Protocol registration in PROSPERO database: CRD42019121130Resumo Objetivo N ós realizamos uma revisão sistemática para avaliar a efetividade e a segurança do Tribulus terrestris no tratamento da disfunção sexual feminina (DSF). Fontes de dados Nós realizados uma busca eletrônica irrestrita nas seguintes bases de dados: MEDLINE, CENTRAL, EMBASE, LILACS,...
Source: Revista Brasileira de Ginecologia e Obstetricia - August 27, 2020 Category: OBGYN Source Type: research
Integrating metabolomics and network pharmacology to explore the protective effect of gross saponins of Tribulus terrestris L. fruit against ischemic stroke in rat
Publication date: Available online 5 August 2020Source: Journal of EthnopharmacologyAuthor(s): Wenjun Guo, Yang Wang, Meiling Fan, Shengxu Xie, Hongyu Zhao, Jifeng Wang, Yue Liu, Dongming Xu, Yajuan Xu (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - August 12, 2020 Category: Drugs & Pharmacology Source Type: research
The Physico-Chemical studies of Khar-e-Khasak (Tribulus terrestris Linn.)
Khar-e-Khasak (Tribulus terrestris Linn) commonly known as Gokhru is an important drug of Unani Medicine. It has been described as diuretic, carminative, antiseptic and widely used by Unani Physicians in various gastrointestinal ailments. In this paper studies carried out to determine the ash values, extractive values, fluorescence analysis and thin layer chromatographic parameters are reported which were performed to standardize the fruit of the plant for its purity. (Source: International Journal of Phytomedicine)
Source: International Journal of Phytomedicine - July 20, 2020 Category: Science Authors: Rasikh Javaid Nengroo Source Type: research
Molecules, Vol. 25, Pages 3274: A Fast and Reliable UHPLC –MS/MS-Based Method for Screening Selected Pharmacologically Significant Natural Plant Indole Alkaloids
Molecules, Vol. 25, Pages 3274: A Fast and Reliable UHPLC–MS/MS-Based Method for Screening Selected Pharmacologically Significant Natural Plant Indole Alkaloids
Molecules doi: 10.3390/molecules25143274
Authors:
Danuše Tarkowská
Many substances of secondary plant metabolism have often attracted the attention of scientists and the public because they have certain beneficial effects on human health, although the reason for their biosynthesis in the plant remains unclear. This is also the case for alkaloids. More than 200 years have passed since the discovery of the first alkaloid (morphine), and several thousand s...
Source: Molecules - July 17, 2020 Category: Chemistry Authors: Danu še Tarkowská Tags: Article Source Type: research
Tribulus Terrestris may decrease muscle damage markers following a high-intensity resistance exercise: a pilot study.
In conclusion, short-term supplementation with TT has no effect on IL-6 and hs-CRP, but may be effective on the reduction of muscle damage enzymes CPK and LDH following high-intensity circuit RE.
PMID: 32375572 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - May 9, 2020 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
Tribulus terrestris ameliorates carbon tetrachloride-induced hepatotoxicity in male rats through suppression of oxidative stress and inflammation.
Abstract
Hepatoprotection is a goal for the harmful effect of several hepatotoxic agents. The present study has been executed to assess the useful impacts of Tribulus terrestris (TT) and silymarin (SLM) against carbon tetrachloride (CCL4)-induced hepatotoxicity. Forty-two male rats were partitioned into six groups: group I: received 0.3% CMC-Na in distilled water, group II: TT (500 mg/kg BW, orally), group III: SLM (200 mg/kg, orally) for 14 consecutive days (on days 11 and 12 intraperitoneal corn oil), group IV: CCL4, group V: TT (500 mg/kg BW) plus CCL4, and group VI: SLM (200 mg/kg orally) plus CCL4...
Source: Environmental Science and Pollution Research International - April 26, 2020 Category: Environmental Health Authors: Kilany OE, El-Beltagy MA, El-Sherbeeny NA Tags: Environ Sci Pollut Res Int Source Type: research
Effect of Tribulus Terrestris L. on Expression of ICAM-1, VCAM-1, E-Selectin and Proteome Profile of Human Endothelial Cells In-Vitro.
CONCLUSION: TT extract and its saponin fraction exerted anti-inflammatory effects on HUVEC and HBMEC lines and reduced the expression of ICAM-1, VCAM-1, and E-selectin. However, the anti-inflammatory effect of aqueous extract was greater than that of saponin fraction. Therefore, TT could be considered as a potential candidate for the treatment or prevention of atherosclerosis.
PMID: 32224542 [PubMed - in process] (Source: Iranian Journal of Immunology)
Source: Iranian Journal of Immunology - April 1, 2020 Category: Allergy & Immunology Tags: Iran J Immunol Source Type: research
Editorial Comment: Improvement of fertility parameters with Tribulus Terrestris and Anacyclus Pyrethrum treatment in male rats
Conclusion TT and AP improved sexual parameters; however, their simultaneous administration had higher improving effects on studied parameters. (Source: International Braz J Urol)
Source: International Braz J Urol - November 7, 2019 Category: Urology & Nephrology Source Type: research
