Neuromodulatory effects induced by the association of Moringa oleifera Lam., Tribulus terrestris L., Undaria pinnatidifida extracts in the hypothalamus
Chem Biodivers. 2024 Mar 25:e202302075. doi: 10.1002/cbdv.202302075. Online ahead of print.ABSTRACTThe present study investigated the role of a commercial formulation constituted by herbal extracts from Rhodiola rosea, Undaria pinnatifida, Tribulus terrestris, and Moringa oleifera. The formulation was analysed for determining the content in total phenols and flavonoids and scavenging/reducing properties. The formulation was also tested on isolated mouse hypothalamus in order to investigate effects on serotonin, dopamine, neuropeptide Y (NPY), and orexin A. The gene expression of gonadrotopin releasing hormone (GnRH) was al...
Source: Chemistry and Biodiversity - March 25, 2024 Category: Biochemistry Authors: Annalisa Chiavaroli Simonetta Cristina Di Simone Alessandra Acquaviva Nilofar Nilofar Maria Loreta Libero Luigi Brunetti Lucia Recinella Sheila Leone Giustino Orlando Gokhan Zengin Maura Di Vito Luigi Menghini Claudio Ferrante Source Type: research
Neuromodulatory effects induced by the association of Moringa oleifera Lam., Tribulus terrestris L., Undaria pinnatidifida extracts in the hypothalamus
Chem Biodivers. 2024 Mar 25:e202302075. doi: 10.1002/cbdv.202302075. Online ahead of print.ABSTRACTThe present study investigated the role of a commercial formulation constituted by herbal extracts from Rhodiola rosea, Undaria pinnatifida, Tribulus terrestris, and Moringa oleifera. The formulation was analysed for determining the content in total phenols and flavonoids and scavenging/reducing properties. The formulation was also tested on isolated mouse hypothalamus in order to investigate effects on serotonin, dopamine, neuropeptide Y (NPY), and orexin A. The gene expression of gonadrotopin releasing hormone (GnRH) was al...
Source: Chemistry and Biodiversity - March 25, 2024 Category: Biochemistry Authors: Annalisa Chiavaroli Simonetta Cristina Di Simone Alessandra Acquaviva Nilofar Nilofar Maria Loreta Libero Luigi Brunetti Lucia Recinella Sheila Leone Giustino Orlando Gokhan Zengin Maura Di Vito Luigi Menghini Claudio Ferrante Source Type: research
Diosgenin biosynthesis investigation in medicinal herb (Tribulus terrestris) by transcriptome analysis
Gene. 2024 Jan 30;893:147937. doi: 10.1016/j.gene.2023.147937. Epub 2023 Oct 29.ABSTRACTNext-generation sequencing (NGS) has revolutionized the analysis of specific genes, pathways, and their regulation in various species. Tribulus terrestris L., an annual medicinal herb of Zygophyllaceae family, has gained significant attention due to its diverse medicinal properties, including anti-inflammatory, antimicrobial, and anti-cancer effects. Diosgenin, a steroidal saponin, is the major bioactive compound responsible for the medicinal importance of T. terrestris. However, there is a paucity of information regarding the genes inv...
Source: Gene - February 21, 2024 Category: Genetics & Stem Cells Authors: Parul Tyagi Mrinalini Prasad Shivangi Mathur Rajiv Ranjan Source Type: research
Diosgenin biosynthesis investigation in medicinal herb (Tribulus terrestris) by transcriptome analysis
Gene. 2024 Jan 30;893:147937. doi: 10.1016/j.gene.2023.147937. Epub 2023 Oct 29.ABSTRACTNext-generation sequencing (NGS) has revolutionized the analysis of specific genes, pathways, and their regulation in various species. Tribulus terrestris L., an annual medicinal herb of Zygophyllaceae family, has gained significant attention due to its diverse medicinal properties, including anti-inflammatory, antimicrobial, and anti-cancer effects. Diosgenin, a steroidal saponin, is the major bioactive compound responsible for the medicinal importance of T. terrestris. However, there is a paucity of information regarding the genes inv...
Source: Gene - February 21, 2024 Category: Genetics & Stem Cells Authors: Parul Tyagi Mrinalini Prasad Shivangi Mathur Rajiv Ranjan Source Type: research
Dietary Supplement with Tribulus terrestris L. Extract Exhibits Protective Effects on Ischemic Stroke Rats
ConclusionsThis study uncovers the mechanisms behind the efficacy of GSTTF in treating ischemic stroke, which not only expands its potential medicinal applications but also confirmed its potential as a dietary supplement. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - October 25, 2023 Category: Food Science Authors: Wenjun Guo,
Jingxuan Yang,
Jifeng Wang,
Xiaohang Xu,
Jinghan Huang,
Yue Liu,
Shengxu Xie,
Yajuan Xu Tags: Research Article Source Type: research
Study of the anti-inflammatory properties of a thick extract of Tribulus terrestris L
Ceska Slov Farm. 2023 Fall;72(4):184-189.ABSTRACTThe most promising direction in the treatment of chronic prostatitis is the use of medicinal plants and preparations based on them, which contain natural compounds with a broad spectrum of pharmacological activity: anti-inflammatory, antimicrobial, reparative, immunomodulatory, hormone-regulating, antisclerotic, etc., and which can provide a complex therapeutic effect on the course of chronic prostatitis. A promising raw material in this direction is Tribulus terrestris L., a herbal preparation traditionally used to treat erectile dysfunction and atherosclerosis. This experi...
Source: Atherosclerosis - October 7, 2023 Category: Cardiology Authors: Saida Yunusova Yaroslav Rozhkovskyi Bohdan Prystupa Svitlana Bohatu Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | PMC:PMC10538161 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
Effects of Aphrodite (an Herbal Compound) on SSRI-Induced Sexual Dysfunctions and Depression in Females with Major Depressive Disorder: Findings from a Randomized Clinical Trial
Conclusions: The pattern of results suggests that compared to placebo, Aphrodite appeared to improve symptoms of sexual dysfunction, depression, and anxiety among females with diagnosed MDD and SSRI-induced sexual dysfunction. Further and similar studies should investigate the underlying psychophysiological mechanisms.PMID:37763782 | DOI:10.3390/medicina59091663 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - September 28, 2023 Category: Universities & Medical Training Authors: Nasrin Shahmoradi Omran Davarinejad Annette Beatrix Br ühl Serge Brand Source Type: research
