Re: The role of 68Ga-PSMA-PET/CT in radiotherapy planning in prostate cancer
Conclusions Holmium laser fragmentation is a safe and effective approach to remove foreign bodies from the bladder. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

REPLY BY THE AUTHORS: Re: Antibiotic prophylaxis prior to urodynamic study in patients with traumatic spinal cord injury. Is there an indication?
Conclusions Holmium laser fragmentation is a safe and effective approach to remove foreign bodies from the bladder. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Re: Antibiotic prophylaxis prior to urodynamic study in patients with traumatic spinal cord injury. Is there an indication?
Conclusions Holmium laser fragmentation is a safe and effective approach to remove foreign bodies from the bladder. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Iatrogenic foreign body in urinary bladder: Holmium laser vs. Ceramic, and the winner is…
Conclusions Holmium laser fragmentation is a safe and effective approach to remove foreign bodies from the bladder. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Whole muscle 18F-choline uptake due to intense physical exercise
ABSTRACT Testicular germ cell tumor is the most common cancer in 20-to 35-years-old men. There are known risk factors such as undescended testicle(s) and history of testicular cancer. Most lesions are germ cell tumors with two main subtypes: seminomas and non-seminomatous germ cell tumors. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Spontaneous gas in a retroperitoneal mass: check the testis!
ABSTRACT Testicular germ cell tumor is the most common cancer in 20-to 35-years-old men. There are known risk factors such as undescended testicle(s) and history of testicular cancer. Most lesions are germ cell tumors with two main subtypes: seminomas and non-seminomatous germ cell tumors. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Synchronous presentation of muscle-invasive urothelial carcinoma of bladder and peritoneal malign mesothelioma
Conclusions To our knowledge, this is the first case of peritoneal malign mesothelioma with synchronous muscle-invasive urothelial carcinoma. Because of the rarity of this condition, there is still no consensus on the definitive treatment protocols, yet. Individualized treatment with multidisciplinary close follow-up might improve the survival outcomes. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Thyroid-like follicular carcinoma of the kidney presenting on a ten year-old prepubertal girl
ABSTRACT The very rare thyroid-like carcinoma of the kidney (TLCK) is microscopically similar to thyroid follicular cell carcinoma (TFCC). Differential diagnosis with secondary thyroid tumors depends on non-reactivity to immunohistochemical (IHC) markers for TFCC (thyroglobulin - TG and TTF1). We herein describe the fourth Pediatric case in literature and extensively review the subject. Only 29 cases were published to the moment. Most cases were asymptomatic and incidentally detected. Most tumors are hyperechoic and hyperdense with low grade heterogenous enhancement on CT and MRI. Most patients were treated with radical ne...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Mating with seminal vesicle-excised male can affect the uterus phospholipid fatty-acids composition during implantation in an experimental mouse model
In this study, we evaluated FA composition of uterus phospholipids during the implantation period in intact and seminal vesicle-excised (SVX) mated female mice. Forty NMRI female mice were divided into control (mated with intact male) and seminal vesicle excised (SVX)-mated (mated with SVX-male) groups. The phospholipid fatty acids composition was monitored during the first five days of pregnancy using gas chromatography and also implantation rate was evaluated on fifth day of pregnancy. Results We found that levels of linoleic acid (LNA) and arachidonic acid (ARA) showed a decreasing trend from the first to the third day ...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Antioxidant action of alpha lipoic acid on the testis and epididymis of diabetic rats: morphological, sperm and immunohistochemical evaluation
ABSTRACT Introduction Chronic hyperglycemia is caused by diabetes mellitus-committed genital morphophysiology, and oxidative stress is one of the main factors involved in this process. Alpha lipoic acid (ALA) can prevent metabolic and morphological changes in diabetic individuals. Objectives In present study, we evaluated the effects of regular ALA consumption on the spermatogenesis and histoarchitecture in the male genital system of diabetic rats. Materials and Methods Thirty-two Wistar rats were divided into groups: Control (CG); Diabetic Control (DCG), receiving commercial diet: ALA Group (ALAG) and Diabetic ALA Group (...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Vesicostomy button: how is it placed, in whom, and how is quality of life affected?
Conclusion The vesicostomy button is an acceptable alternative to traditional vesicostomy and CIC. The morbidity of the button is quite low. Endoscopic insertion is the optimal technique. QOL is equivalent in patients with vesicostomy button and those who perform CIC. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Voiding symptoms obtained by open versus directed anamnesis as predictors of voiding dysfunction in women
Conclusions VS-Open may predict better voiding dysfunction than VS-Directed in women. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Association between enuresis and obesity in children with primary monosymptomatic nocturnal enuresis
Conclusions Obesity is associated with severe enuresis and low efficacy of behavioral therapy in children with nocturnal enuresis. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Efficacy and tolerability of mirabegron in female patients with overactive bladder symptoms after surgical treatment for stress urinary incontinence
Conclusion Mirabegron is safe, effective and tolerable in the long-term treatment of females with OAB symptoms after surgery for s tress urinary incontinence. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Correlation of tools for objective evaluation of infravesical obstruction of men with lower urinary tract symptoms
ABSTRACT Purpose To identify how the most frequently used parameters in daily clinical practice diagnosing bladder outlet obstruction (BOO) due to benign prostate hyperplasia (BPH) correlate to each other. Materials and methods The study included 452 patients with lower urinary tract symptoms (LUTS) of the UNICAMP urology outpatient clinic of LUTS. Inclusion criteria: patients with BOO due to BPH who agreed to participate in the study. Exclusion criteria: patients with urinary tract infection, neurological diseases that compromised the lower urinary tract, prior prostatic surgery, radiotherapy or urethral stenosis. Patient...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

A prospective study assessing feasibility of performing percutaneous nephrolithotomy in chronic kidney disease patients - What factors affect the outcome?
Conclusion Our results indicate that most patients of renal calculi with CKD show improvement or stabilization of renal function with aggressive stone removal. Improvement is more in patients who have mild to moderate CKD. Aggressive management of comorbidities, peri-operative UTI and complications may delay or avoid progression of CKD status in such patients. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Editorial Comment: Study of kidney morphologic and structural changes related to different ischemia times and types of clamping of the renal vascular pedicle
This study aimed to study morphological and renal structural changes in relation to different ischemic times and types of renal vascular pedicle clamping. Methods Sixteen pigs were divided into two groups (n = 8): Group AV - unilateral clamping of the renal artery and vein and Group A - unilateral clamping of the renal artery only, both with the contralateral kidney used as control. Serial biopsies were performed at 0, 10, 20, 30, 40, 50, 60, 70, 80, and 90 minutes after clamping. Results there is a correlation between the occurrence of renal damage as a function of time (p
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Study of kidney morphologic and structural changes related to different ischemia times and types of clamping of the renal vascular pedicle
This study aimed to study morphological and renal structural changes in relation to different ischemic times and types of renal vascular pedicle clamping. Methods Sixteen pigs were divided into two groups (n = 8): Group AV - unilateral clamping of the renal artery and vein and Group A - unilateral clamping of the renal artery only, both with the contralateral kidney used as control. Serial biopsies were performed at 0, 10, 20, 30, 40, 50, 60, 70, 80, and 90 minutes after clamping. Results there is a correlation between the occurrence of renal damage as a function of time (p
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Challenging risk factors for right and left laparoscopic adrenalectomy: A single centre experience with 272 cases
Conclusions During the learning period of LA, EBL is higher on the right side. Due to the greater risk of bleeding complications on the right side even on the hands of experienced surgeons, extra care and preoperative planning are required in patients with pheochromocytoma, metastatic masses and masses>5cm in size. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Intraoperative serious complications of laparoscopic urological surgeries: a single institute experience of 4,380 procedures
This study aimed to share a single institute experience of 4,380 procedures about in-traoperative serious complications of laparoscopic urological surgeries. From January 2005 to December 2013, 4,380 cases of laparoscopic urological surgeries were recruited in our department. The distribution, incidence, and characteristics of intraoperative serious complications were retrospectively sorted out and analyzed. The surgeries were divided into three groups: very difficult (VD), difficult (D), and easy (E). The com ¬plication at Satava class II was defined to be serious. One hundred thirty one cases with intraoperative seri...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

A census of laparoscopic and robotic urological practice: a survey of minimally invasive surgery department of the Brazilian Society of Urology
ABSTRACT Minimally invasive urologic surgery has been developing in Brazil and now is a routine part of care in many regions and patients with different conditions benefit from it. Training in laparoscopic and robotic surgery has evolved and concerns exist both over the quality of surgical training and the practical effect on results of the urological training. This is an unprecedented study which undertook a census to determinate the current state of laparoscopic and robotic urological practice and to know the mains barriers to adequate practice in Brazil. In august 2017, surveys, consisting of an anonymous questionnaire ...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Is possible to rule out clinically significant prostate cancer using PI-RADS v2 for the assessment of prostate MRI?
ABSTRACT Objectives To evaluate the diagnostic performance and interobserver agreement of PI-RADS v2. Materials and Methods In this Institutional Review Board approved single-center retrospective study, 98 patients with clinically suspected PCa who underwent 3-T multiparametric MRI followed by MRI/TRUS fusion-guided prostate biopsy were included from June 2013 to February 2015. Two radiologists (R1 and R2) with 8 and 1 years of experience in abdominal radiology reviewed the MRI scans and assigned PI-RADS v2 scores in all prostate zones. PI-RADS v2 were compared to MRI/TRUS fusion-guided biopsy results, which were classifie...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Detection of clinically significant prostate cancer with PI-RADS v2 scores, PSA density, and ADC values in regions with and without mpMRI visible lesions
ABSTRACT Purpose To determine if PSAD, PSADtz, and ADC values improve the accuracy of PI-RADS v2 and identify men whose concurrent systematic biopsy detects clinically significant cancer on areas without mpMRI visible lesions. Materials and methods Single reference-center, cross-sectional, retrospective study of consecutive men with suspected or known low to intermediate-risk prostate cancer who underwent 3T mpMRI and TRUS-MRI fusion biopsy from 07/15/2014 to 02/17/2018. Cluster-corrected logistic regression analyses were utilized to predict clinically significant prostate cancer (Gleason score ≥ 3+4) at targeted mpMRI ...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Factors affecting urinary continence and sexual potency recovery after robotic-assisted radical prostatectomy
ABSTRACT Introduction Robot-assisted radical prostatectomy (RARP) is the most recent surgical technique for localized prostate cancer. The Da Vinci (Intuitive Surgical, Sunnyvale, CA) system was first introduced in Brazil in 2008, with a fast growing number of surgeries performed each year. Objective Our primary endpoint is to analyze possible predictors of functional outcomes, related to patient and tumor features. As secondary endpoint, describe functional outcomes (urinary continence and sexual potency) from RARP performed in the S írio-Libanês Hospital (SLH), a private institution, in São Paulo, fro...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

A comparison of perioperative outcome between robot-assisted and laparoscopic radical prostatectomy: experience of a single institution
Conclusion In RLRP, Ep-RLRP w as proved a safe and effective approach based on the perioperative results compared to Tp-RLRP. Ep-RLRP and Ep-LPR provides equivalent perioperative and pathological outcomes. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Decrease in skeletal muscle index one year after radical cystectomy as a prognostic indicator in patients with urothelial bladder cancer
Conclusions The decrease in SMI after surgery might be a negative prognostic factor for OS in patients who underwent RC to treat UBC. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Nonsecretory intestinocystoplasty: postoperative outcomes of 25 years
The objective of bladder augmentation (BA) is to create a low-pressure reservoir with adequate capacity. Despite its benefits, the use of intestinal patches in bladder enlargement provides a high risk of developing complications and BA with demucosalised bowel represents a potential alternative. Therefore, this study evaluated urological parameters and long-term clinical follow-up of patients submitted to non-secretory BA in a single center with 25 years of experience. Materials and Methods Patients treated with BA underwent urological evaluation, which included history, physical examination and urodynamic study. The main ...
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Editorial Comment: External validation of nomogram to predict inguinal lymph node metastasis in patients with penile cancer and clinically negative lymph nodes
Conclusions In our study, the previously developed nomogram that was applied to our population had low accuracy and low precision for correctly identifying patients with PC who have positive ILNs. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

External validation of nomogram to predict inguinal lymph node metastasis in patients with penile cancer and clinically negative lymph nodes
Conclusions In our study, the previously developed nomogram that was applied to our population had low accuracy and low precision for correctly identifying patients with PC who have positive ILNs. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

A comprehensive literature-based equation to compare cost-effectiveness of a flexible ureteroscopy program with single-use versus reusable devices
Conclusions The cost-effectiveness of a flexible ureteroscopy program is dependent of several aspects. We have developed a equation to allow a literature-based and adaptable decision model to every interested stakeholder. Disposable devices are already a reality and will progressively become the standard as manufacturing price falls. (Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Enhanced recovery after surgery (ERAS) in radical cystectomy patients: from consensus to evidences
(Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Age and Body Mass Index: the most important factors of urinary and erectile function recovery after robotic assisted radical prostatectomy
(Source: International Braz J Urol)
Source: International Braz J Urol - September 2, 2019 Category: Urology & Nephrology Source Type: research

Re: Comparison of Gleason upgrading rates in transrectal ultrasound systematic random biopsies versus US-MRI fusion biopsies for prostate cancer
Abstract Vasitis or inflammation of the vas deferens is a rarely described condition categorized as either generally asymptomatic vasitis nodosa or the acutely painful infectious vasitis. Vasitis nodosa, the commonly described inflammation of the vas deferens, is benign and usually associated with a history of vasectomy. Clinically, patients present with a nodular mass and are often asymptomatic and require no specific treatment. (Source: International Braz J Urol)
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Re: Prognosis of prostate cancer and prostate - specific antigen levels
Abstract Vasitis or inflammation of the vas deferens is a rarely described condition categorized as either generally asymptomatic vasitis nodosa or the acutely painful infectious vasitis. Vasitis nodosa, the commonly described inflammation of the vas deferens, is benign and usually associated with a history of vasectomy. Clinically, patients present with a nodular mass and are often asymptomatic and require no specific treatment. (Source: International Braz J Urol)
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Vasitis: a clinical confusion diagnosis with inguinal hernia
Abstract Vasitis or inflammation of the vas deferens is a rarely described condition categorized as either generally asymptomatic vasitis nodosa or the acutely painful infectious vasitis. Vasitis nodosa, the commonly described inflammation of the vas deferens, is benign and usually associated with a history of vasectomy. Clinically, patients present with a nodular mass and are often asymptomatic and require no specific treatment. (Source: International Braz J Urol)
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Tumor-like appearance of Spermatic Granuloma
We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The r...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review
We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The r...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Low serum vitamin D is associated with an increased likelihood of acquired premature ejaculation
Abstract Purpose: To investigate the relationship between 25-hydroxyvitamin D (25 (OH) D) levels and acquired premature ejaculation (PE). Materials and Methods: A total of 97 patients with acquired PE and 64 healthy men as a control group selected from volunteers without PE attending our Andrology Outpatient Clinic between November 2016 and April 2017 were included the study. All patients were considered to have acquired PE if they fulfilled the criteria of the second Ad Hoc International Society for Sexual Medicine Committee. Premature ejaculation diagnostic tool questionnaires were used to assessment of PE and all partic...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Balloon dilation for failed pyeloplasty in children?
Conclusions: Balloon dilatation surgery is safe for children, but it is not recommended for faile d pyeloplasty in that group of patients, owing to the low success rate. (Source: International Braz J Urol)
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Editorial comment: Cross-cultural adaptation and validation of the neurogenic bladder symptom score questionnaire for brazilian portuguese
ABSTRACT Objective: To cross-culturally adapt and check for the reliability and validity of the neurogenic bladder symptom score questionnaire to Brazilian Portuguese, in patients with spinal cord injury and multiple sclerosis. Materials and Methods: The questionnaire was culturally adapted according to international guidelines. The Brazilian version was applied in patients diagnosed with neurogenic bladder due to spinal cord injury or multiple sclerosis, twice in a range of 7 to 14 days. Psychometric properties were tested such as content validity, construct validity, internal consistency, and test-retest reliability. Res...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Cross-cultural adaptation and validation of the neurogenic bladder symptom score questionnaire for brazilian portuguese
ABSTRACT Objective: To cross-culturally adapt and check for the reliability and validity of the neurogenic bladder symptom score questionnaire to Brazilian Portuguese, in patients with spinal cord injury and multiple sclerosis. Materials and Methods: The questionnaire was culturally adapted according to international guidelines. The Brazilian version was applied in patients diagnosed with neurogenic bladder due to spinal cord injury or multiple sclerosis, twice in a range of 7 to 14 days. Psychometric properties were tested such as content validity, construct validity, internal consistency, and test-retest reliability. Res...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Predicting urine output after kidney transplantation: development and internal validation of a nomogram for clinical use
Conclusions: The predominant influence of CIT on UO1 rapidly wanes and is replaced by indicators of functional recovery (mainly UO1) and allograft's immunologic acceptance (AR absence). Mean absolute errors for nomograms were 0.08 mL/Kg h (UO1) and 0.05 mL/Kg h (UO8). (Source: International Braz J Urol)
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Retrograde vs. antegrade flexible nephroscopy for detection of residual fragments following PNL: a prospective study with computerized tomography control
ABSTRACT Introduction: The main aim of stone surgery is to establish stone free status. Performing flexible nephroscopy is an effective tool in this manner. The aim of this study was to evaluate the role of retrograde flexible nephroscopy for detection of residual fragments following percutaneous nephrolithotomy (PNL) in comparison with antegrade approach. Materials and Methods: Data of 137 patients underwent ECIRS was collected prospectively. In all cases following stone clearance, collecting system was checked for residual fragments. First antegrade than retrograde flexible nephroscopy was performed and success rates to ...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Trends in renal calculus composition and 24-hour urine analyses in patients with neurologically derived musculoskeletal deficiencies
Conclusions: Among patients with NDMD, metabolic factors may play a more significant role in renal calculus formation than previously believed. There is still a high incidence of carbonate apatite calculi, which could be attributed to bacteriuria. However, obesity, low urine volumes, hypocitraturia, and hyperoxaluria suggest an underrecognized metabolic contribution to stone formation in this population. (Source: International Braz J Urol)
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Laparoscopic radical cystectomy with intracorporeal ileal conduit: one center experience and clinical outcomes
ABSTRACT Purpose: To introduce our experience with intracorporeal ileal conduit and evaluate the safety and feasibility of this endoscopic urinary diversion. Materials and Methods: Between March 2014 and July 2017, thirty-six consecutive patients underwent laparoscopic radical cystectomy with intracorporeal ileal conduit. Patients ’ demographic data, perioperative data, 90-days postoperative outcomes and complications were collected. This cohort were divided into two groups of 18 patients each by chronological order of the operations to facilitate comparison of clinical data. Data were evaluated using the students &r...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

lncRNA CCAT1 promotes bladder cancer cell proliferation, migration and invasion
ABSTRACT Objective: To study the expression patterns of long noncoding RNA (lncRNA) colon cancer-associated transcript 1 (CCAT1) and the changes in cell proliferation, apoptosis, migration and invasion induced by silencing CCAT1 in bladder cancer cells. Materials and Methods: The expression levels of CCAT1 were determined using realtime quantitative polymerase chain reaction in cancerous tissues and paired normal tissues from 34 patients with bladder cancer. The relationship between clinical characteristics and CCAT1 expression was analyzed. And then we conducted cell experiments. Bladder urothelial carcinoma cell lines T2...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Prognostic significance of inflammation-based prognostic scoring in patients with upper urinary tract urothelial carcinoma
ABSTRACT Objectives: To investigate whether Glasgow Prognostic Score has prognostic significance in patients with upper urinary urothelial carcinoma. Patients and methods: We retrospectively reviewed the clinical records of 74 patients with upper urinary urothelial carcinoma. We set the cut-off value for C-reactive protein as 1.0mg/dL, and 3.5mg/dL for albumin as Glasgow Prognostic Score. Their blood data including albumin and C-reactive protein for Glasgow Prognostic Score and cytokeratin 19 fragment 21-1 as a tumor marker were measured before starting treatment. The patients were stratified into three groups with Glasgow...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Surgical treatment for renal masses in the elderly: analysis of oncological, surgical and functional outcomes
Conclusions: Surgical treatment in elderly patients with renal tumor is as safe as in younger individuals and does not increase the risk of ESRD. However, cancer specific survival among these patients remains shorter than in younger patients. (Source: International Braz J Urol)
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

A higher circulating concentration of 25-hydroxyvitamin-D decreases the risk of renal cell carcinoma: a case-control study
ABSTRACT Objective: To investigate the relationship between vitamin D status, using circulating 25-hydroxyvitamin D [25 (OH) D], and renal cell carcinoma (RCC) risk in a case-control study, because the association between the two is unclear in China. Materials and Methods: A total of 135 incident RCC cases were matched with 135 controls by age and sex. The blood samples were collected on the first day of hospitalization before surgery to measure plasma 25 (OH) D. Logistic regression analyses were used to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs) with adjustment for several confounders (e.g. age, ge...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research

Predictors of complication after adrenalectomy
ABSTRACT Purpose: To investigate risk factors for complications in patients undergoing adrenalectomy. Materials and Methods: A retrospective search of our institutional database was performed of patients who underwent adrenalectomy, between 2014 and 2018. Clinical parameters and adrenal disorder characteristics were assessed and correlated to intra and post-operative course. Complications were analyzed within 30-days after surgery. A logistic regression was performed in order to identify independent predictors of morbidity in patients after adrenalectomy. Results: The files of 154 patients were reviewed. Median age and Bod...
Source: International Braz J Urol - June 27, 2019 Category: Urology & Nephrology Source Type: research