Pretreatment of Tribulus terrestris L. causes anti-ischemic cardioprotection through MAPK mediated anti-apoptotic pathway in rat
Publication date: March 2019Source: Biomedicine & Pharmacotherapy, Volume 111Author(s): P.L. Reshma, P. Binu, Nair Anupama, R.C. Vineetha, S. Abhilash, R. Harikumaran Nair, K.G. RaghuAbstractThe aim of the present investigation is the evaluation and elucidation of the mechanisms by which Tribulus terrestris L. methanol extract (TTM) devoid of fruit exhibits protection against cardiac ischemia in in vitro (H9c2 cell line) and in vivo (Wistar rat) model. Tribulus terrestris L. (TT) was used in this study to evaluate the efficacy against cardiac ischemia employing in vitro and in vivo models of myocardial ischemia. H9c2 cells...
Source: Biomedicine and Pharmacotherapy - January 17, 2019 Category: Drugs & Pharmacology Source Type: research
Anti-Helicobacter pylori, cytotoxicity and catalytic activity of biosynthesized gold nanoparticles: Multifaceted application
Publication date: January 2019Source: Arabian Journal of Chemistry, Volume 12, Issue 1Author(s): V. Gopinath, S. Priyadarshini, D. MubarakAli, Mun Fai Loke, N. Thajuddin, Naiyf S. Alharbi, Tejabhiram Yadavalli, M. Alagiri, Jamuuna VadiveluAbstractAn unpretentious way to synthesize different sized gold nanoparticles (GNPs) using the dried fruit extract of Tribulus terrestris has been investigated. GNPs were formed due to the reduction of chloroauric acid (HAuCl4) treated with the T. terrestris fruit extract. Formation of GNPs was periodically characterized by UV–Vis spectroscopy. IR spectrum revealed that phytochemicals i...
Source: Arabian Journal of Chemistry - January 6, 2019 Category: Chemistry Source Type: research
Supplements with purported effects on muscle mass and strength
Conclusion In summary, despite their popularity, there is little evidence supporting the use of most supplements, and some of them have been even proven ineffective or potentially associated with adverse effects. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 2, 2019 Category: Nutrition Source Type: research
Evaluation of cytological and genetic effects of Tribulus terrestris fruit aqueous extract on cultured human lymphocytes
Publication date: January 2019Source: Saudi Journal of Biological Sciences, Volume 26, Issue 1Author(s): Sameer H. Qari, S.M. El-AssouliAbstractThe current study was carried out to evaluate the genotoxic aspects of the aqueous extracts of the Tribulus terrestris fruits by comet assay and cytogenetic procedures conditions on cultured human peripheral blood lymphocyte. After the treatment of the lymphocytes with four concentrations of the aqueous fruit extract of T. terrestris (10, 20, 40 and 80 mg/L) for 24 h it was noticed that, the presence of micronuclei and/or chromosomal aberration were monitored and a signif...
Source: Saudi Journal of Biological Sciences - January 1, 2019 Category: Biology Source Type: research
In vitro and in vivo effects of Tribulus terrestris on immunological parameters, lymphocyte proliferation, and DNA integrity in sheep
In conclusion, TTE could modulate the immune functions and induce lymphocyte transformation in rams. (Source: Small Ruminant Research)
Source: Small Ruminant Research - December 8, 2018 Category: Zoology Source Type: research
Hypospermia Improvement in Dogs Fed on a Nutraceutical Diet.
Authors: Ciribé F, Panzarella R, Pisu MC, Di Cerbo A, Guidetti G, Canello S
Abstract
Male dog infertility may represent a serious concern in the canine breeding market. The aim of this clinical evaluation was to test the efficacy of a commercially available nutraceutical diet, enriched with Lepidium meyenii, Tribulus terrestris, L-carnitine, zinc, omega-3 (N-3) fatty acids, beta-carotene, vitamin E, and folic acid, in 28 male dogs suffering from infertility associated with hypospermia. All dogs received the diet over a period of 100 days. At the end of the evaluation period, no adverse effects, including ...
Source: The Scientific World Journal - December 6, 2018 Category: Science Tags: ScientificWorldJournal Source Type: research
In vitro and In vivo Effects of Tribulus terrestris on Some Immunological Parameters, Lymphocyte Proliferation, and DNA Integrity in Sheep
In conclusion, TTE could modulate the immune functions and induce lymphocyte transformation in rams. (Source: Small Ruminant Research)
Source: Small Ruminant Research - October 26, 2018 Category: Zoology Source Type: research
Tribulus terrestris improves metronidazole-induced impaired fertility in the male mice
Conclusion: The fruit extract of TT may emerge as an effective herbal remedy, correcting the drug-induced fertility impairments in males.Keywords: Female mice, fertility, male mice, metronidazole,Tribulus terrestris. (Source: African Health Sciences)
Source: African Health Sciences - August 14, 2018 Category: African Health Source Type: research
Effect of vaginal suppository on bacterial vaginitis based on Persian medicine (Iranian traditional medicine): a randomised double blind clinical study.
This study showed that Forzejeh, which is an herbal Persian medicine preparation, has a therapeutic effect the same as metronidazole in bacterial vaginosis. Impact statement What is already known on this subject? Bacterial vaginosis (BV) is a common problem in women. Common antibiotics for the treatment of BV include: metronidazole, tinidazole and clindamycin. Unfortunately, treatments often occur with a recurrence and failure. Therefore, alternative treatments are necessary. Many natural treatments are recommended for this condition in Persian Traditional Medicine sources. One of them is the vaginal suppository "Forzejeh"...
Source: Journal of Obstetrics and Gynaecology - August 8, 2018 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Phytochemical analysis and antimicrobial activity of some medicinal plants against selected pathogenic microorganisms
Publication date: October 2018Source: Microbial Pathogenesis, Volume 123Author(s): P. Arulmozhi, S. Vijayakumar, T. KumarAbstractThe aim of the present study is to investigate the antimicrobial potency of leaves from various extracts of Capparis zeylanica, Streblus asper and Tribulus terrestris were evaluated. In addition, this is the first report on MIC, MBC/MFC antimicrobial activities of above mentioned plants and also identify the phytochemical, functional groups by GC-MS and FT-IR respectively. Soxhlet extraction method was used for preparation of different extracts viz., aqueous, petroleum ether, ethyl acetate and me...
Source: Microbial Pathogenesis - July 20, 2018 Category: Infectious Diseases Source Type: research
214. Modification of milk decoction (Ksheerapaka) of Tribulus terrestris into dehydrated milk powder – A proposed technology integration
Publication date: April–June 2018Source: Journal of Ayurveda and Integrative Medicine, Volume 9, Issue 2, Supplement 1Author(s): P.K. Vineeth, Abhaya Kumar Mishra (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - July 19, 2018 Category: Complementary Medicine Source Type: research
Optimization and comparison of different techniques for complete extraction of saponins from T. terrestris
Publication date: March 2018Source: Journal of Applied Research on Medicinal and Aromatic Plants, Volume 8Author(s): Boris Sarvin, Elena Stekolshchikova, Igor Rodin, Andrey Stavrianidi, Oleg ShpigunAbstractUltrasound-assisted1 (UAE), refluxing2 (RE), low pressure refluxing3 (LPRE) and Soxhlet4 (SE) extraction techniques were developed for determination of steroidal saponins content in Tribulus terrestris L. Extraction parameters for UAE (solvent base: methanol, ethanol, isopropanol and acetonitrile; the ratio of solvent to solid: 50–400 mL/g; isopropanol and acetonitrile concentration: 30–100%; extraction time: 15–...
Source: Journal of Applied Research on Medicinal and Aromatic Plants - July 10, 2018 Category: Complementary Medicine Source Type: research
Proteomic analysis reveals the renoprotective effect of Tribulus terrestris against obesity-related glomerulopathy in rats.
In conclusion, TT may play a protective role against ORG in rats.
PMID: 29984733 [PubMed - as supplied by publisher] (Source: Biological and Pharmaceutical Bulletin)
Source: Biological and Pharmaceutical Bulletin - July 6, 2018 Category: Drugs & Pharmacology Authors: Jiang YH, Jiang LY, Wu S, Jiang WJ, Xie L, Li W, Yang CH Tags: Biol Pharm Bull Source Type: research
Optimization and comparison of different techniques for complete extraction of saponins from T. terrestris
Publication date: March 2018Source: Journal of Applied Research on Medicinal and Aromatic Plants, Volume 8Author(s): Boris Sarvin, Elena Stekolshchikova, Igor Rodin, Andrey Stavrianidi, Oleg ShpigunAbstractUltrasound-assisted1 (UAE), refluxing2 (RE), low pressure refluxing3 (LPRE) and Soxhlet4 (SE) extraction techniques were developed for determination of steroidal saponins content in Tribulus terrestris L. Extraction parameters for UAE (solvent base: methanol, ethanol, isopropanol and acetonitrile; the ratio of solvent to solid: 50–400 mL/g; isopropanol and acetonitrile concentration: 30–100%; extraction time: 15–...
Source: Journal of Applied Research on Medicinal and Aromatic Plants - July 5, 2018 Category: Complementary Medicine Source Type: research
Saponins of Tribulus terrestris attenuated neuropathic pain induced with vincristine through central and peripheral mechanism
AbstractThe study comprises exploring the effects of saponins fromTribulus terrestris (TT) in attenuating the neuropathic pain caused by vincristine (100 μg/ml i.p.) for 10 days (in two 5 day cycles with 2 days pause). Mechanical hyperalgesia and allodynia were assessed by Randall–Sellitto and electronic von Frey tests, respectively. Chemical- induced nociception was assessed by formalin test. Neurophysiological effect of the extract was eval uated by recording sciatic functional index (SFI) on the test days (7, 10, 14, and 21) and sciatic nerve conduction velocity test (SNCV) on the last day. Inflammatory mediator...
Source: Inflammopharmacology - June 25, 2018 Category: Drugs & Pharmacology Source Type: research
