Examining the relationship between head trauma and opioid use disorder: A systematic review
CONCLUSION: Findings indicate that therapists and clinicians must consider a risk profile for persons with TBI and follow an integrated care approach to account for mental health, prior substance misuse, presenting somatic symptoms, and current medication regimen during evaluation.PMID:38533717 | DOI:10.5055/jom.0846 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - March 27, 2024 Category: Addiction Authors: Ali Abid Maria Paracha Iva Çepele Awais Paracha Joseph Rueve Akbar Fidahussain Humza Rehman McKimmon Engelhardt Noor Alyasiry Zohair Siddiqui Satvik Vasireddy Bishal Kadariya Nikith Rao Rohan Das Wilson Rodriguez Dixie Meyer Source Type: research
Role of opioid use in gastrointestinal obstruction and perforation: A retrospective review
CONCLUSION: Pain killers should always be prescribed with caution and for a short duration. Alternative options for pain relief should be made available, and doctors should be trained. Drug abusers tend to have a gastrointestinal complication at an early age, which means they are prone to further complications and recurrence if the problem is not addressed on time.PMID:38533716 | DOI:10.5055/jom.0850 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - March 27, 2024 Category: Addiction Authors: Divya Bishnoi Priyanka Sharma Anant Kumar Rathi Source Type: research
Examining the relationship between head trauma and opioid use disorder: A systematic review
CONCLUSION: Findings indicate that therapists and clinicians must consider a risk profile for persons with TBI and follow an integrated care approach to account for mental health, prior substance misuse, presenting somatic symptoms, and current medication regimen during evaluation.PMID:38533717 | DOI:10.5055/jom.0846 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - March 27, 2024 Category: Addiction Authors: Ali Abid Maria Paracha Iva Çepele Awais Paracha Joseph Rueve Akbar Fidahussain Humza Rehman McKimmon Engelhardt Noor Alyasiry Zohair Siddiqui Satvik Vasireddy Bishal Kadariya Nikith Rao Rohan Das Wilson Rodriguez Dixie Meyer Source Type: research
Molecules, Vol. 29, Pages 1480: Monitoring Pharmaceuticals and Personal Care Products in Healthcare Effluent Wastewater Samples and the Effectiveness of Drug Removal in Wastewater Treatment Plants Using the UHPLC-MS/MS Method
This study reveals the prevalence of several different drugs; mean concentrations of 702 μg L−1 of iomeprol, 48.8 μg L−1 of iopromide, 29.9 μg L−1 of gabapentin, 42.0 μg L−1 of caffeine and 82.5 μg L−1 of paracetamol were present. An analysis of 20 samples from ten WWTPs revealed different removal efficiencies for different analytes. Paracetamol was present in the inflow samples of all ten WWTPs and its removal efficiency was 100%. Analytes such as caffeine, ketoprofen, naproxen or atenolol showed hi...
Source: Molecules - March 27, 2024 Category: Chemistry Authors: Lucia Molnarova Tatana Halesova Daniela Tomesova Marta Vaclavikova Zuzana Bosakova Tags: Article Source Type: research
The impact of tightened prescribing restrictions for PBS-subsidised opioid medicines and the introduction of half-pack sizes, Australia, 2020-21: an interrupted time series analysis
CONCLUSIONS: The introduction of new PBS rules for subsidised opioid medicines was followed by a decline in PBS-subsidised dispensing. Some people may have bypassed the new restrictions by switching to private prescriptions, but our findings suggest that opioid medicine use in Australia declined as a result of the new restrictions.PMID:38522006 | DOI:10.5694/mja2.52257 (Source: Medical Journal of Australia)
Source: Medical Journal of Australia - March 24, 2024 Category: General Medicine Authors: Forrest C Koch Jake Olivier Jonathan Brett Nicholas A Buckley Natasa Gisev Sallie Pearson Benjamin Daniels Source Type: research
The impact of tightened prescribing restrictions for PBS-subsidised opioid medicines and the introduction of half-pack sizes, Australia, 2020-21: an interrupted time series analysis
CONCLUSIONS: The introduction of new PBS rules for subsidised opioid medicines was followed by a decline in PBS-subsidised dispensing. Some people may have bypassed the new restrictions by switching to private prescriptions, but our findings suggest that opioid medicine use in Australia declined as a result of the new restrictions.PMID:38522006 | DOI:10.5694/mja2.52257 (Source: Med J Aust)
Source: Med J Aust - March 24, 2024 Category: General Medicine Authors: Forrest C Koch Jake Olivier Jonathan Brett Nicholas A Buckley Natasa Gisev Sallie Pearson Benjamin Daniels Source Type: research
The impact of tightened prescribing restrictions for PBS-subsidised opioid medicines and the introduction of half-pack sizes, Australia, 2020-21: an interrupted time series analysis
CONCLUSIONS: The introduction of new PBS rules for subsidised opioid medicines was followed by a decline in PBS-subsidised dispensing. Some people may have bypassed the new restrictions by switching to private prescriptions, but our findings suggest that opioid medicine use in Australia declined as a result of the new restrictions.PMID:38522006 | DOI:10.5694/mja2.52257 (Source: Medical Journal of Australia)
Source: Medical Journal of Australia - March 24, 2024 Category: General Medicine Authors: Forrest C Koch Jake Olivier Jonathan Brett Nicholas A Buckley Natasa Gisev Sallie Pearson Benjamin Daniels Source Type: research
The impact of tightened prescribing restrictions for PBS-subsidised opioid medicines and the introduction of half-pack sizes, Australia, 2020-21: an interrupted time series analysis
CONCLUSIONS: The introduction of new PBS rules for subsidised opioid medicines was followed by a decline in PBS-subsidised dispensing. Some people may have bypassed the new restrictions by switching to private prescriptions, but our findings suggest that opioid medicine use in Australia declined as a result of the new restrictions.PMID:38522006 | DOI:10.5694/mja2.52257 (Source: Med J Aust)
Source: Med J Aust - March 24, 2024 Category: General Medicine Authors: Forrest C Koch Jake Olivier Jonathan Brett Nicholas A Buckley Natasa Gisev Sallie Pearson Benjamin Daniels Source Type: research
The impact of tightened prescribing restrictions for PBS-subsidised opioid medicines and the introduction of half-pack sizes, Australia, 2020-21: an interrupted time series analysis
CONCLUSIONS: The introduction of new PBS rules for subsidised opioid medicines was followed by a decline in PBS-subsidised dispensing. Some people may have bypassed the new restrictions by switching to private prescriptions, but our findings suggest that opioid medicine use in Australia declined as a result of the new restrictions.PMID:38522006 | DOI:10.5694/mja2.52257 (Source: Medical Journal of Australia)
Source: Medical Journal of Australia - March 24, 2024 Category: General Medicine Authors: Forrest C Koch Jake Olivier Jonathan Brett Nicholas A Buckley Natasa Gisev Sallie Pearson Benjamin Daniels Source Type: research
The impact of tightened prescribing restrictions for PBS-subsidised opioid medicines and the introduction of half-pack sizes, Australia, 2020-21: an interrupted time series analysis
CONCLUSIONS: The introduction of new PBS rules for subsidised opioid medicines was followed by a decline in PBS-subsidised dispensing. Some people may have bypassed the new restrictions by switching to private prescriptions, but our findings suggest that opioid medicine use in Australia declined as a result of the new restrictions.PMID:38522006 | DOI:10.5694/mja2.52257 (Source: Med J Aust)
Source: Med J Aust - March 24, 2024 Category: General Medicine Authors: Forrest C Koch Jake Olivier Jonathan Brett Nicholas A Buckley Natasa Gisev Sallie Pearson Benjamin Daniels Source Type: research
REKOVER study protocol: a pRospective patient treatment rEgistry of tramadol and dexKetoprofen trometamol oral fixed-dose combination (SKUDEXA) in mOderate to seVere acutE pain in Real-world setting in Asia
Introduction
Satisfactory management of acute pain remains a major medical challenge despite the availability of multiple therapeutic options including the fixed-dose combination (FDC) drugs. Tramadol and dexketoprofen trometamol (TRAM/DKP) 75/25 mg FDC was launched in 2018 in Asia and is widely used in the management of moderate to severe acute pain. There are limited data on its effectiveness and safety in Asian patients, and therefore, a need to better understand its usage patterns in clinical practice. We aim to understand the usage pattern of TRAM/DKP FDC, its effectiveness and tolerability in patients with moderate t...
Source: BMJ Open - March 19, 2024 Category: General Medicine Authors: Ho, K. Y., Gyanwali, B., Dimayuga, C., Eufemio, E. M., Bernardo, E., Raju, G., Chong, K. W., Waithayayothin, K., Ona, L., Castro, M. A. L., Sawaddiruk, P., Salvador, R. C., Roohi, S. A., Tangwiwat, S., Wilairatana, V., Oon, Z. H., Gupta, A., Nagrale, D. Tags: Open access, Anaesthesia Source Type: research
The effect of an ultrasound-guided sacral erector spinae plane block on the postoperative pain of lumbar discectomy: a randomized controlled trial
CONCLUSIONS: In lumbar discectomy surgery, ultrasound-guided SESPB provided adequate analgesia by reducing opioid consumption and pain scores without complications.PMID:38482636 | DOI:10.23736/S0375-9393.23.17830-8 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 14, 2024 Category: Anesthesiology Authors: Bilge Olgun Kele ş Elvan Tekir Yilmaz Source Type: research
Comparative Risk of Injury with Concurrent Use of Opioids and Skeletal Muscle Relaxants
In conclusion, the relative injury rate associated with different SMRs used concurrently with the three most dispensed opioids appears to vary depending on the specific opioid and the order of combination initiation. If confirmed by future studies, clinicians should consider the varying injury rates when prescribing SMRs to individuals using hydrocodone, oxycodone, and tramadol.PMID:38482733 | DOI:10.1002/cpt.3248 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - March 14, 2024 Category: Drugs & Pharmacology Authors: Cheng Chen Sean Hennessy Colleen M Brensinger Todd A Miano Warren B Bilker Sascha Dublin Sophie P Chung John R Horn Anika Tiwari Charles E Leonard Source Type: research
The effect of an ultrasound-guided sacral erector spinae plane block on the postoperative pain of lumbar discectomy: a randomized controlled trial
CONCLUSIONS: In lumbar discectomy surgery, ultrasound-guided SESPB provided adequate analgesia by reducing opioid consumption and pain scores without complications.PMID:38482636 | DOI:10.23736/S0375-9393.23.17830-8 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 14, 2024 Category: Anesthesiology Authors: Bilge Olgun Kele ş Elvan Tekir Yilmaz Source Type: research
Comparative Risk of Injury with Concurrent Use of Opioids and Skeletal Muscle Relaxants
In conclusion, the relative injury rate associated with different SMRs used concurrently with the three most dispensed opioids appears to vary depending on the specific opioid and the order of combination initiation. If confirmed by future studies, clinicians should consider the varying injury rates when prescribing SMRs to individuals using hydrocodone, oxycodone, and tramadol.PMID:38482733 | DOI:10.1002/cpt.3248 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - March 14, 2024 Category: Drugs & Pharmacology Authors: Cheng Chen Sean Hennessy Colleen M Brensinger Todd A Miano Warren B Bilker Sascha Dublin Sophie P Chung John R Horn Anika Tiwari Charles E Leonard Source Type: research
