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Tramadol effects on physical performance and sustained attention during a 20-min indoor cycling time-trial: A randomised controlled trial - Holgado D, Zandonai T, Zabala M, Hopker J, Perakakis P, Luque-Casado A, Ciria L, Guerra-Hernandez E, Sanabria D.
OBJECTIVES: To investigate the effect of tramadol on performance during a 20-min cycling time-trial (Experiment 1), and to test whether sustained attention would be impaired during cycling after tramadol intake (Experiment 2). DESIGN: Randomized, d... (Source: SafetyLit)
Source: SafetyLit - November 14, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

November 2017 RxNorm Release Available for Download
The RxNorm November 2017 Release is now available for download. The November release is consistent with the 2017AB Unified Medical Language System (UMLS) Metathesaurus Release Files. A new Qualitative Distinction “Matrix Delivery” is included to help distinguish tramadol containing drugs that cannot be prescribed interchangeably with other tramadol drugs. (Source: UMLS News)
Source: UMLS News - November 6, 2017 Category: Databases & Libraries Source Type: news

Nigeria:Rising Drug Abuse
[This Day] Everyday, over a 500,000 bottles of codeine are consumed by young Nigerians across the country, same with the intake of tramadol, rohypnol, marijuana, and other opioids, an alarming trend that has subtly eaten deeply into the Nigerian fabric with children of all classes having a field day abusing these drugs. But parents, stakeholders and the society continue to live in self-denial as a time bomb waits to explode. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 1, 2017 Category: African Health Source Type: news

A 15-year overview of increasing tramadol utilisation and associated mortality and the impact of tramadol classification in the United Kingdom - Chen TC, Chen LC, Knaggs RD.
This study aimed to develop hypotheses to explain the increasing tramadol utilisation, evaluate the impact of tramadol classification, and explore the trend between tramadol utilisation and related deaths in the United Kingdom. METHODS: Th... (Source: SafetyLit)
Source: SafetyLit - September 28, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Ghana: High Dose Tramadol Floods Market
[Business Day] President of the Pharmaceutical Society of Ghana (PSGH), Pharm. Benjamin Kwame Botwe has warned against the high proliferation and abuse of high dose tramadol on the market. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 25, 2017 Category: African Health Source Type: news

Opioid painkiller overdoses more than double in a decade
Number of hospital admissions in England rose to 11,660 last year as doctors say drugs are being prescribed too readilyThe number of patients admitted to hospital for overdosing on powerful and potentially addictive opioid painkillers has more than doubled in a decade, with doctors saying it is the “very worrying” consequence of the drugs being prescribed too readily.Data from NHS Digital shows an increase in people attending hospital with poisoning from prescription opioids such as codeine, morphine, oxycodone,fentanyl and tramadol rising from 4,891 in 2005-06 to 11,660 last year in England.Continue reading......
Source: Guardian Unlimited Science - September 13, 2017 Category: Science Authors: Sarah Marsh Tags: Drugs Health NHS Science Society UK news Source Type: news

FDA to Examine Opioids in Kids' Cough Meds ... Again
(MedPage Today) -- Special meeting to focus on products with codeine and tramadol (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - August 21, 2017 Category: Pediatrics Source Type: news

Tramadol: for Pain (Ultram, Ultram ER, Conzip)
Title: Tramadol: for Pain (Ultram, Ultram ER, Conzip)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 8/17/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - August 17, 2017 Category: Rheumatology Source Type: news

Tramadol Side Effects
Title: Tramadol Side EffectsCategory: MedicationsCreated: 8/3/2017 12:00:00 AMLast Editorial Review: 8/3/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - August 3, 2017 Category: Drugs & Pharmacology Source Type: news

Tramadol (Ultram) Side Effects
Title: Tramadol (Ultram) Side EffectsCategory: MedicationsCreated: 8/3/2017 12:00:00 AMLast Editorial Review: 8/3/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - August 3, 2017 Category: Rheumatology Source Type: news

FDA Drug Safety Communication: FDA evaluating the risks of using the pain medicine tramadol in children aged 17 and younger
[9-21-2015] The U.S. Food and Drug Administration (FDA) is investigating the use of the pain medicine tramadol in children ages 17 years and younger, because of the rare but serious risk of slowed or difficult breathing. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 1, 2017 Category: Drugs & Pharmacology Source Type: news

Tramadol May Offer a Better Option for Opioid Withdrawal Tramadol May Offer a Better Option for Opioid Withdrawal
Extended-release formulations of the analgesic tramadol hydrochloride may provide an attractive alternative to two commonly used medications for opioid withdrawal.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 14, 2017 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Extended-Release Tramadol May Ease Opioid Withdrawal Symptoms (FREE)
By Kelly Young Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM Extended-release tramadol may help reduce withdrawal symptoms in patients being treated for opioid use disorder, according to a JAMA … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 12, 2017 Category: Primary Care Source Type: news

Clinical trial examines tramadol to treat opioid withdrawal
Researchers at Johns Hopkins University have found the drug tramadol, when combined with other therapies, may be effective for treating opioid withdrawal. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 12, 2017 Category: Consumer Health News Source Type: news

Tramadol with or without paracetamol (acetaminophen) for cancer pain
This Cochrane Review finds very low quality data suggesting tramadol produced pain relief in some adults with pain due to cancer and is not as effective as morphine. There is no evidence for children. The place of tramadol in managing cancer pain and its role as step 2 of the WHO analgesic ladder is unclear. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 28, 2017 Category: Consumer Health News Source Type: news

Great New Toxicology Podcast
In the first episode of “The Dantastic Mr. Tox & Howard Show,” Drs. Dan Rusyniak and Howard Greller — formerly of the Journal of Medical Toxicology Podcast — have a superb discussion about the current expanding opioid crisis with Dr. David Juurlink from Sunnybrook Health Sciences Centre in Toronto. Topics covered include opioid-induced hyperalgesia, the key difference between relieving pain and relieving suffering, and why tramadol is generally such a poor drug. The episode is smart, succinct, and highly recommended. I look forward to future podcasts. To listen, cli...
Source: The Poison Review - June 16, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical daniel rusyniak dantastic mr. tox & howard david juurlink howard greller podcast Source Type: news

Emergence Agitation Control in Pediatric Adenotonsillectomy Emergence Agitation Control in Pediatric Adenotonsillectomy
Emergence agitation is a frequent complication in children undergoing adenotonsillectomy. Which is a better choice for controlling postoperative pain and agitation: tramadol or dexmedetomidine?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 10, 2017 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Tramadol vs. Vicodin
Title: Tramadol vs. VicodinCategory: MedicationsCreated: 5/9/2017 12:00:00 AMLast Editorial Review: 5/9/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - May 9, 2017 Category: Drugs & Pharmacology Source Type: news

'Unnecessary' painkillers could leave thousands addicted, doctors warn
Prescriptions for powerful opioid painkillers have doubled from 12m to 24m in past decade, NHS Digital figures revealPrescription pain killers: share your stories with usPowerful and potentially addictive opiate painkillers are being handed out too readily, leading doctors have warned after it emerged that the number of times the drugs are being prescribed in the UK has doubled in the past decade.The Faculty of Pain Medicine and the Royal Pharmaceutical Society said they were worried about the high and growing use of opioid drugs such as codeine and tramadol – while other experts warn that hundreds of thousands of pa...
Source: Guardian Unlimited Science - May 5, 2017 Category: Science Authors: Sarah Marsh Tags: Drugs Health UK news NHS Science Society Source Type: news

Tramadol vs. Codeine
Title: Tramadol vs. CodeineCategory: MedicationsCreated: 5/3/2017 12:00:00 AMLast Editorial Review: 5/3/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - May 3, 2017 Category: Drugs & Pharmacology Source Type: news

Trump nominee to head FDA clears key panel, moves to full Senate for vote
The Senate health committee voted 14-9 Thursday to approve physician Scott Gottlieb to be the next commissioner of the Food and Drug Administration, sending the nomination to the full Senate. All 12 Republicans on the committee voted in favor of Gottlieb, a former venture capitalist who served as an FDA deputy commissioner during the George […]Related:FDA cracks down on companies pushing vegetable extracts and creams as cancer curesFDA warns of dangers of codeine and tramadol for children and breast-feeding mothersFDA nominee says nation’s opioid crisis is as serious as Ebola, Zika threats (Source: Washington ...
Source: Washington Post: To Your Health - April 27, 2017 Category: Consumer Health News Source Type: news

Dangerous bleeding after childbirth could be treated with a $1 injection
One of the most heart-wrenching public health problems facing the world has been the large number of women who die during or after childbirth despite all our medical progress. Melinda Gates has called the issue one of her top priorities and committed more than $1.5 billion from her family’s foundation to the cause. Countless scientists have explored the issue […]Related:Surgeon general is removed by Trump administration, replaced by deputy for nowFDA warns of dangers of codeine and tramadol for children and breast-feeding mothersA rare tick-borne disease infected a baby, the first case in a...
Source: Washington Post: To Your Health - April 26, 2017 Category: Consumer Health News Source Type: news

FDA cracks down on companies pushing vegetable extracts and creams as cancer cures
Asparagus extract. Exotic teas. Topical creams for your pet — and you. These and dozens of other products are being touted falsely as having "anti-cancer" properties, according to federal regulators who are trying to stop the practice. The Food and Drug Administration, in warning letters released Tuesday, ordered 14 companies to stop making the bogus claims or […]Related:FDA warns of dangers of codeine and tramadol for children and breast-feeding mothersThe federal panel that opposed prostate cancer screening just changed its mindPhysician recommendations about breast cancer screening vary,...
Source: Washington Post: To Your Health - April 26, 2017 Category: Consumer Health News Source Type: news

FDA cracks down on companies pushing fraudulent cancer claims
The Food and Drug Administration ordered 14 companies to stop making bogus claims about cancer cures — including asparagus extract, exotic teas and topical creams for pets — or face possible product seizures and criminal prosecution. The letters covered more than five-dozen unapproved products that the companies touted as preventing, treating or curing cancer, a violation of […]Related:FDA warns of dangers of codeine and tramadol for children and breast-feeding mothersThe federal panel that opposed prostate cancer screening just changed its mindPhysician recommendations about breast cancer scre...
Source: Washington Post: To Your Health - April 25, 2017 Category: Consumer Health News Source Type: news

Tramadol vs. Hydrocodone
Title: Tramadol vs. HydrocodoneCategory: MedicationsCreated: 4/24/2017 12:00:00 AMLast Editorial Review: 4/24/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - April 24, 2017 Category: Drugs & Pharmacology Source Type: news

D.C. Week: Trump, House GOP Trying Again for ACA Repeal
(MedPage Today) -- Just say'no'to codeine or tramadol for kids under 12, FDA urges (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 22, 2017 Category: Psychiatry Source Type: news

Surgeon general is removed by Trump administration, replaced by deputy for now
Surgeon General Vivek H. Murthy released a landmark report on the country's addiction epidemic, calling it a “moral test for America." Related:FDA warns of dangers of codeine and tramadol for children and breast-feeding mothersA rare tick-borne disease infected a baby, the first case in a new stateAntidepressants not as harmful during pregnancy as previously thought, a new study shows (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - April 22, 2017 Category: Consumer Health News Source Type: news

FDA: No Prescription Codeine, Tramadol for Kids Under 12
On April 20, the FDA issued a safety announcement restricting the use of codeine and tramadol in children and requiring labeling changes to prescription medications containing these ingredients. (Source: AAFP News)
Source: AAFP News - April 21, 2017 Category: Primary Care Source Type: news

FDA warns against codeine, tramadol for children
The Food and Drug Administration says medications containing codeine or tramadol should not be given to children, and warns that these drugs could cause serious risks including difficulty breathing and death. (Source: CNN.com - Health)
Source: CNN.com - Health - April 21, 2017 Category: Consumer Health News Source Type: news

FDA strengthens warning against codeine and tramadol for children
The Food and Drug Administration says medications containing codeine or tramadol should not be given to children, and warns that these drugs could cause serious risks including difficulty breathing and death. (Source: CNN.com - Health)
Source: CNN.com - Health - April 21, 2017 Category: Consumer Health News Source Type: news

Don't Give Kids Medicines With Codeine, Tramadol: FDA
Title: Don't Give Kids Medicines With Codeine, Tramadol: FDACategory: Health NewsCreated: 4/20/2017 12:00:00 AMLast Editorial Review: 4/21/2017 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - April 21, 2017 Category: Pediatrics Source Type: news

FDA: Codeine Now Contraindicated for Pain and Cough in Kids (FREE)
By Amy Orciari Herman Edited by Andr é Sofair, MD, MPH, and William E. Chavey, MD, MS The FDA has issued new warnings against using prescription codeine and tramadol in children and adolescents. Reviewing adverse event reports from nearly 50 years, the agency found 64 reports … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - April 21, 2017 Category: Primary Care Source Type: news

FDA: Don't Give Kids Meds With Codeine, Tramadol
Agency strengthens warning labels on these medications to address dangers (Source: WebMD Health)
Source: WebMD Health - April 20, 2017 Category: Consumer Health News Source Type: news

F.D.A. Strengthens Warnings for Painkillers in Children
Children and nursing mothers should not take codeine or tramadol, the agency cautions. (Source: NYT Health)
Source: NYT Health - April 20, 2017 Category: Consumer Health News Authors: CATHERINE SAINT LOUIS Tags: Pain-Relieving Drugs Children and Childhood Breastfeeding Codeine Parenting Labeling and Labels (Product) Food and Drug Administration Source Type: news

Don't Use Tramadol and Codeine in Kids Under 12, FDA Warns Don't Use Tramadol and Codeine in Kids Under 12, FDA Warns
The two opioids pose the risk for potentially fatal respiratory depression in young children. The FDA also is restricting their use in older children.News Alerts (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - April 20, 2017 Category: Drugs & Pharmacology Tags: Pediatrics News Alert Source Type: news

US regulators BAN under-12s from using strong cough syrups
Makers of pain medicines that contain codeine and tramadol will now have to change the labels to ban users from giving them to children under 12 years old. (Source: the Mail online | Health)
Source: the Mail online | Health - April 20, 2017 Category: Consumer Health News Source Type: news

FDA warns of dangers of codeine and tramadol for children and breast-feeding mothers
The Food and Drug Administration on Thursday warned parents against giving their children prescription medicines with codeine and tramadol, saying the drugs could lead to severe breathing problems and death. The agency said it would require manufacturers to make label changes to warn that the drugs shouldn't be used for anyone under 12 and should […]Related:A rare tick-borne disease infected a baby, the first case in a new stateAntidepressants not as harmful during pregnancy as previously thought, a new study showsA protein from human umbilical cords revitalizes memory — at least in mice (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - April 20, 2017 Category: Consumer Health News Source Type: news

Don ’ t Give Kids Medicines With Codeine, Tramadol: FDA
Agency strengthens warning labels on these medications to address dangers (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - April 20, 2017 Category: Respiratory Medicine Tags: Pediatrics, Pharmacy, Pulmonology, News, Source Type: news

FDA: Codeine, Tramadol unsafe for children under 12
Parents shouldn't give children medications containing codeine or tramadol, because they can cause life-threatening breathing problems, the FDA warned Thursday. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 20, 2017 Category: Consumer Health News Source Type: news

Don't Give Kids Medicines with Codeine, Tramadol: FDA
Agency strengthens warning labels on these medications to address dangers Source: HealthDay Related MedlinePlus Pages: Breastfeeding, Medicines and Children, Pain Relievers (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 20, 2017 Category: Consumer Health News Source Type: news

FDA: No Codeine or Tramadol for Children Under 12 -- Period
(MedPage Today) -- Warnings for children with medical conditions, breastfeeding moms (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - April 20, 2017 Category: American Health Source Type: news

A rare tick-borne disease infected a baby, the first case in a new state
It started with fever and vomiting. Then the 5-month-old baby developed facial twitching, stiffening of his right arm and seizures. The family rushed him to Connecticut Children’s Medical Center. Clinicians there performed tests, including a brain MRI that showed clear signs of a serious infection. The testing showed that the baby didn’t have meningitis, an […]Related:FDA warns of dangers of codeine and tramadol for children and breast-feeding mothersAntidepressants not as harmful during pregnancy as previously thought, a new study showsA protein from human umbilical cords revitalizes memory — at l...
Source: Washington Post: To Your Health - April 20, 2017 Category: Consumer Health News Source Type: news

FDA Drug Safety Communication: FDA restricts use of prescription codeine pain and cough medicines and tramadol pain medicines in children; recommends against use in breastfeeding women
FDA is restricting the use of codeine and tramadol medicines in children. Codeine is approved to treat pain and cough, and tramadol is approved to treat pain. These medicines carry serious risks, including slowed or difficult breathing and death, which appear to be a greater risk in children younger than 12 years and must not be used in these children. These medicines should also be limited in some older children. Single-ingredient codeine and all tramadol-containing products are FDA-approved only for use in adults. We are also recommending against using codeine and tramadol medicines in breastfeeding mothers due to possib...
Source: FDA Center for Drug Evaluation and Research - What's New - April 20, 2017 Category: Drugs & Pharmacology Source Type: news

FDA statement from Douglas Throckmorton, M.D., deputy center director for regulatory programs, Center for Drug Evaluation and Research, on new warnings about the use of codeine and tramadol in children & nursing mothers
The health and safety of children is a top priority at the FDA, which is why today we are requiring a series of changes to the labeling of two types of opioid medications in order to help better protect children from serious risks associated with these medicines – codeine (found in some prescription pain and cough medicines and some over-the-counter cough medicines) and tramadol (found in some prescription pain medicines). (Source: Food and Drug Administration)
Source: Food and Drug Administration - April 20, 2017 Category: American Health Source Type: news

Don't Give Kids Medicines With Codeine, Tramadol: FDA
THURSDAY, April 20, 2017 -- Parents shouldn't give their children any medications containing the narcotics codeine or tramadol, because they can cause life-threatening breathing problems, the U.S. Food and Drug Administration warned... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 20, 2017 Category: Journals (General) Source Type: news

Codeine and Tramadol Can Cause Breathing Problems for Children
The FDA is strengthening drug labels for codeine and tramadol to protect children and nursing babies. (Source: FDA Consumer Health Information Updates)
Source: FDA Consumer Health Information Updates - April 20, 2017 Category: Consumer Health News Source Type: news

Drugs Vanish at Some VA Hospitals
WASHINGTON (AP) — Federal authorities are stepping up investigations at Department of Veterans Affairs medical centers due to a sharp increase in opioid theft, missing prescriptions or unauthorized drug use by VA employees since 2009, according to government data obtained by The Associated Press. Doctors, nurses or pharmacy staff at federal hospitals — the vast majority within the VA system — siphoned away controlled substances for their own use or street sales, or drugs intended for patients simply disappeared. Aggravating the problem is that some VA hospitals have been lax in tracking drug supplies. Co...
Source: Arkansas Business - Health Care - February 20, 2017 Category: American Health Source Type: news

Trends in Tramadol: Pharmacology, Metabolism, and Misuse Trends in Tramadol: Pharmacology, Metabolism, and Misuse
Learn about the unique characteristics of tramadol, its pharmacogenomic considerations, and its potential for abuse in this comprehensive review.Anesthesia & Analgesia (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 15, 2017 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Some addicts are so desperate for drugs that they ’ re now taking medication prescribed to pets
It was the third time Heather Pereira had taken her golden retriever to the same neighborhood animal clinic in Kentucky. The first was on a Friday in October 2014, when Pereira took the injured 4-year-old dog to the Elizabethtown Animal Hospital, not far from Louisville. After the veterinarian sewed up a cut, Pereira requested Tramadol, a drug used to treat […]Related:No, Gwyneth Paltrow, women should not put jade eggs in their vaginas, gynecologist saysNIH Director Francis Collins to stay in his post for nowNew global coalition launched to create vaccines, prevent epidemics (Source: Washing...
Source: Washington Post: To Your Health - January 23, 2017 Category: Consumer Health News Source Type: news