Qdolo (Tramadol Hydrochloride Oral Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 24, 2021 Category: Drugs & Pharmacology Source Type: news

Urologic Surgery Tied to Persistent Opioid Usage, Particularly With Tramadol Urologic Surgery Tied to Persistent Opioid Usage, Particularly With Tramadol
People who undergo urologic surgery are more likely to have persistent opioid usage afterward than matched non-surgical controls, and patients have a higher risk of persistent use with tramadol than other opioids, a new study suggests.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 24, 2021 Category: Surgery Tags: Urology News Source Type: news

Nonmedical use of tramadol among secondary school students in Benin, Africa - Bio-Sya A, Gandjo HJ, Klikpo ETE, Kouglenou O, Agbanlinsou AC, Damien GB, Kpatchavi AC, Allabi AC.
This study aimed to assess the prevalence, factors assoc... (Source: SafetyLit)
Source: SafetyLit - August 19, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Marked and prolonged serotonin toxicity in a tramadol-poisoned patient with a pharmacokinetic study - Bianconi G, Malissin I, Labat L, Khoudour N, Houz é P, Pallet N, Megarbane B, Declèves X.
BACKGROUND: Tramadol poisoning rarely causes serotonin toxicity, which mechanisms remain poorly understood. We investigated alterations in tramadol pharmacokinetics in a tramadol-poisoned patient who presented with marked and prolonged serotonin toxicity. ... (Source: SafetyLit)
Source: SafetyLit - July 25, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Codeine and tramadol use in athletes: a potential for abuse - Zandonai T, Escorial M, Peir ó AM.
Analgesic use by athletes is common (Overbye, 2020). It has been observed that athletes used analgesics up to four times more often than their age-matched general population (Holgado et al., 2018a). Notably, codeine and tramadol are not included in the WAD... (Source: SafetyLit)
Source: SafetyLit - July 3, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Acute tramadol ingestion with transient acute kidney injury in an adolescent female - Mike TB, DeVault H, Blackford MG.
Renal toxicity has been described with tramadol overdoses; however, it is typically associated with rhabdomyolysis, multiorgan failure and/or mortality. Our patient was a 16-year-old female who was evaluated following an intentional tramadol ingestion, est... (Source: SafetyLit)
Source: SafetyLit - May 28, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

DR MICHAEL MOSLEY: Should doctors now prescribe dummy pills to ease pain?
DR MICHAEL MOSLEY: Deaths from taking high-strength painkillers, such as tramadol and codeine, have doubled over the past ten years, there is clearly a need for safe and effective alternatives. (Source: the Mail online | Health)
Source: the Mail online | Health - April 16, 2021 Category: Consumer Health News Source Type: news

Women in England almost twice as likely as men to be prescribed opiate painkillers
Experts worried about high use of drugs such as codeine and tramadol after prescriptions rose during Covid pandemic‘I was told to live with it’: women tell of doctors dismissing their painWomen in England are almost twice as likely as men to be prescribed powerful and potentially addictive opiate painkillers, prompting experts to warn that female pain is overly medicated and not properly investigated.The number of people prescribed drugs such as codeine and tramadol – often used for chronic pain – rose to 1.18 million in the first 10 months of 2020. Of these, 745,047 were women and 434,697 were men, a Guardian anal...
Source: Guardian Unlimited Science - April 16, 2021 Category: Science Authors: Sarah Marsh and Pamela Duncan Tags: Women's health Drugs Science Society UK news Source Type: news

Study shows opioid use among US patients with knee osteoarthritis costs 14 billion dollars in societal costs
(Wiley) Although guidelines do not recommend use of opioids to manage pain for individuals with knee osteoarthritis, a recent study published early online in Arthritis Care& Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Professionals, estimates that 858,000 Americans use opioids such as tramadol and oxycodone for their knee pain, equating to $14 billion in lifetime opioid-related societal costs, or nearly $0.5 billion annually. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2021 Category: International Medicine & Public Health Source Type: news

Machine learning algorithms to predict seizure due to acute tramadol poisoning - Behnoush B, Bazmi E, Nazari SH, Khodakarim S, Looha MA, Soori H.
This study was designed to develop and evaluate machine learning algorithms for predicting seizure due to acute tramadol poisoning, identifying high-risk patients and facilitating appropriate clinical decision-making. METHODS: Several... (Source: SafetyLit)
Source: SafetyLit - February 8, 2021 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Nigeria: Increased Risk As Drug Smugglers Rebrand Tramadol
[ISS] Manufacturers in India have rebranded the opioid Tramadol to Tafrodol so as to evade detection by customs officials at Nigeria's ports and borders. While the name change makes the drug look like Tramadol, Tafrodol contains two ingredients that should not be combined and can reportedly cause respiratory infection, coma and even instant death. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 28, 2021 Category: African Health Source Type: news

FDA Drug Safety Communication: FDA restricts use of prescription codeine pain and cough medicines and tramadol pain medicines in children; recommends against use in breastfeeding women
FDA is restricting the use of codeine and tramadol medicines in children. Codeine is approved to treat pain and cough, and tramadol is approved to treat pain. These medicines carry serious risks, including slowed or difficult breathing and death, which appear to be a greater risk in children younger than 12 years and must not be used in these children. These medicines should also be limited in some older children. Single-ingredient codeine and all tramadol-containing products are FDA-approved only for use in adults. We are also recommending against using codeine and tramadol medicines in breastfeeding mothers due to possib...
Source: FDA Center for Drug Evaluation and Research - What's New - January 7, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Assessment of tramadol blood concentration in cases of acute tramadol overdose - Tawfik HM, Abd El Wahab MB.
Tramadol is a synthetic analgesic drug that has been used for acute and chronic pain. It has a potential risk of addiction and overdoses due to its common illegal abuse. The analgesic effect of tramadol is dose dependent and in medical literature no study ... (Source: SafetyLit)
Source: SafetyLit - December 28, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Avenue Therapeutics gets regulatory update for intravenous tramadol, says Cipla
In October this year, Avenue Therapeutics Inc had received a complete response letter (CRL) from the USFDA which stated that the regulator has determined that it cannot approve the application for IV tramadol in its present form. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 18, 2020 Category: Pharmaceuticals Source Type: news

Cumberland County Man Admits Conspiring to Distribute Opioids, Launder Millions of Dollars in Drug Proceeds
FDA OCI, Alton Chatmon, Bridgeton NJ, guilty plea, Tramadol, synthetic opioid, butalbital, prescription pills, money laundering, drug trafficking proceeds, shell companies, pharmacist, suspended license, wire transfer, conspiracy, Fioricet, fictitious businesses, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - December 17, 2020 Category: Medical Law Authors: DOJ Source Type: news