Effect of soy isoflavone supplementation on blood pressure: a meta-analysis of randomized controlled trials
Previous experimental studies have suggested that the consumption of soy isoflavones may have a potential impact on lowering blood pressure. Nevertheless, epidemiological studies have presented conflicting out... (Source: Nutrition Journal)
Source: Nutrition Journal - March 7, 2024 Category: Nutrition Authors: Lifu Lei, Suocheng Hui, Yushi Chen, Hongjia Yan, Jian Yang and Shiwen Tong Tags: Review Source Type: research
Phenolics and flavonoids from Polygonum posumbu and comparision of flavonoid compounds content in different tissues (leaves, stems and roots)
Fitoterapia. 2024 Feb 24:105864. doi: 10.1016/j.fitote.2024.105864. Online ahead of print.ABSTRACTThe growing global need for antioxidative phenolics and flavonoids for maintenance of human health resulted into search of new sustainable unexplored medicinal plants used by the traditional healers for various ailments. Many synthetic based products of phenolics and flavonoids have been used, however the demand of eco-friendly, natural herbal based products are increasing. As a result, the current study aims to explore traditional potential of Polygonum posumbu related to its phenolics and flavonoids. Optimization of extracti...
Source: Fitoterapia - February 26, 2024 Category: Biochemistry Authors: Premi Devi Pukhrambam Khomdram Khedashwori Devi Chingoileima Maibam Roseeta Devi Mutum Moirangthem Lakshmipriyari Devi Sudripta Das Source Type: research
Phenolics and flavonoids from Polygonum posumbu and comparision of flavonoid compounds content in different tissues (leaves, stems and roots)
Fitoterapia. 2024 Feb 24:105864. doi: 10.1016/j.fitote.2024.105864. Online ahead of print.ABSTRACTThe growing global need for antioxidative phenolics and flavonoids for maintenance of human health resulted into search of new sustainable unexplored medicinal plants used by the traditional healers for various ailments. Many synthetic based products of phenolics and flavonoids have been used, however the demand of eco-friendly, natural herbal based products are increasing. As a result, the current study aims to explore traditional potential of Polygonum posumbu related to its phenolics and flavonoids. Optimization of extracti...
Source: Fitoterapia - February 26, 2024 Category: Biochemistry Authors: Premi Devi Pukhrambam Khomdram Khedashwori Devi Chingoileima Maibam Roseeta Devi Mutum Moirangthem Lakshmipriyari Devi Sudripta Das Source Type: research
Phenolics and flavonoids from Polygonum posumbu and comparision of flavonoid compounds content in different tissues (leaves, stems and roots)
Fitoterapia. 2024 Feb 24:105864. doi: 10.1016/j.fitote.2024.105864. Online ahead of print.ABSTRACTThe growing global need for antioxidative phenolics and flavonoids for maintenance of human health resulted into search of new sustainable unexplored medicinal plants used by the traditional healers for various ailments. Many synthetic based products of phenolics and flavonoids have been used, however the demand of eco-friendly, natural herbal based products are increasing. As a result, the current study aims to explore traditional potential of Polygonum posumbu related to its phenolics and flavonoids. Optimization of extracti...
Source: Fitoterapia - February 26, 2024 Category: Biochemistry Authors: Premi Devi Pukhrambam Khomdram Khedashwori Devi Chingoileima Maibam Roseeta Devi Mutum Moirangthem Lakshmipriyari Devi Sudripta Das Source Type: research
Dietary Plant Metabolites Induced Epigenetic Modification as a Novel Strategy for the Management of Prostate Cancer
Mini Rev Med Chem. 2024 Feb 21. doi: 10.2174/0113895575283895240207065454. Online ahead of print.ABSTRACTProstate cancer is a widespread malignancy among men, with a substantial global impact on morbidity and mortality. Despite advances in conventional therapies, the need for innovative and less toxic treatments remains a priority. Emerging evidence suggests that dietary plant metabolites possess epigenetic-modifying properties, making them attractive candidates for prostate cancer treatment. The present work reviews the epigenetic effects of dietary plant metabolites in the context of prostate cancer therapy. We first out...
Source: Mini Reviews in Medicinal Chemistry - February 22, 2024 Category: Chemistry Authors: Vaibhav Singh Ekta Shirbhate Rakesh Kore Aditya Mishra Varsha Johariya Ravichandran Veerasamy Amit K Tiwari Harish Rajak Source Type: research
Dietary Plant Metabolites Induced Epigenetic Modification as a Novel Strategy for the Management of Prostate Cancer
Mini Rev Med Chem. 2024 Feb 21. doi: 10.2174/0113895575283895240207065454. Online ahead of print.ABSTRACTProstate cancer is a widespread malignancy among men, with a substantial global impact on morbidity and mortality. Despite advances in conventional therapies, the need for innovative and less toxic treatments remains a priority. Emerging evidence suggests that dietary plant metabolites possess epigenetic-modifying properties, making them attractive candidates for prostate cancer treatment. The present work reviews the epigenetic effects of dietary plant metabolites in the context of prostate cancer therapy. We first out...
Source: Mini Reviews in Medicinal Chemistry - February 22, 2024 Category: Chemistry Authors: Vaibhav Singh Ekta Shirbhate Rakesh Kore Aditya Mishra Varsha Johariya Ravichandran Veerasamy Amit K Tiwari Harish Rajak Source Type: research
Dietary Plant Metabolites Induced Epigenetic Modification as a Novel Strategy for the Management of Prostate Cancer
Mini Rev Med Chem. 2024 Feb 21. doi: 10.2174/0113895575283895240207065454. Online ahead of print.ABSTRACTProstate cancer is a widespread malignancy among men, with a substantial global impact on morbidity and mortality. Despite advances in conventional therapies, the need for innovative and less toxic treatments remains a priority. Emerging evidence suggests that dietary plant metabolites possess epigenetic-modifying properties, making them attractive candidates for prostate cancer treatment. The present work reviews the epigenetic effects of dietary plant metabolites in the context of prostate cancer therapy. We first out...
Source: Mini Reviews in Medicinal Chemistry - February 22, 2024 Category: Chemistry Authors: Vaibhav Singh Ekta Shirbhate Rakesh Kore Aditya Mishra Varsha Johariya Ravichandran Veerasamy Amit K Tiwari Harish Rajak Source Type: research
Dietary Plant Metabolites Induced Epigenetic Modification as a Novel Strategy for the Management of Prostate Cancer
Mini Rev Med Chem. 2024 Feb 21. doi: 10.2174/0113895575283895240207065454. Online ahead of print.ABSTRACTProstate cancer is a widespread malignancy among men, with a substantial global impact on morbidity and mortality. Despite advances in conventional therapies, the need for innovative and less toxic treatments remains a priority. Emerging evidence suggests that dietary plant metabolites possess epigenetic-modifying properties, making them attractive candidates for prostate cancer treatment. The present work reviews the epigenetic effects of dietary plant metabolites in the context of prostate cancer therapy. We first out...
Source: Mini Reviews in Medicinal Chemistry - February 22, 2024 Category: Chemistry Authors: Vaibhav Singh Ekta Shirbhate Rakesh Kore Aditya Mishra Varsha Johariya Ravichandran Veerasamy Amit K Tiwari Harish Rajak Source Type: research
Molecules, Vol. 29, Pages 955: ROS Scavenging Effect of Selected Isoflavones in Provoked Oxidative Stress Conditions in Human Skin Fibroblasts and Keratinocytes
neusz Sowa
Isoflavones, belonging to polyphenolic compounds, show structural similarity to natural estrogens, and in this context, they have been extensively studied. Some of them are also applied as cosmetic additives; however, little is known regarding their effects on skin cells. In this investigation, common isoflavones, including genistein, daidzein, glycitein, formononetin, and biochanin A, as well as coumestrol, were evaluated for antioxidant activity and their impact on human skin fibroblasts and keratinocytes. Antioxidant effects were assessed using DPPH, ABTS, and FRAP tests, and the ability to scavenge react...
Source: Molecules - February 22, 2024 Category: Chemistry Authors: Magdalena W ójciak Piotr Drozdowski Aleksandra Ziemlewska Martyna Zag órska-Dziok Zofia Nizio ł-Łukaszewska Tomasz Kubrak Ireneusz Sowa Tags: Communication Source Type: research
The Use of Isoflavones as Lung Cancer Chemoprevention Agents and their Implications in Treatment through Radio Sensitization
Curr Med Chem. 2024 Feb 1. doi: 10.2174/0109298673278897231229121524. Online ahead of print.ABSTRACTEpidemiological trends in cancer research show that lung cancer can affect up to 1 in 15 men and 1 in 17 women. With incidence rates as high as these and significant associated mortality and morbidity, it is no wonder that lung cancer is one of the main areas of research focused on cancer. Advances in targeted treatments and specialized irradiation protocols have allowed the treatment of more advanced cases. However, as the patient numbers grow, so does the need for cancer-preventive strategies. The present narrative review ...
Source: Current Medicinal Chemistry - February 19, 2024 Category: Chemistry Authors: Efstratios Athanasiou Savvas Papageorgiou Marianna Foteini Dafni Ioannis Kelesis Maria Vasileiou Theodora Tatsiou Vasiliki Kouveloglou Panagiotis Kanatas Ioannis Stouras Athanasios Gatsis Vasiliki Taxiarchoula Agiassoti Petros Nasimpian Dimitrios Dafnoudi Source Type: research
The Use of Isoflavones as Lung Cancer Chemoprevention Agents and their Implications in Treatment through Radio Sensitization
Curr Med Chem. 2024 Feb 1. doi: 10.2174/0109298673278897231229121524. Online ahead of print.ABSTRACTEpidemiological trends in cancer research show that lung cancer can affect up to 1 in 15 men and 1 in 17 women. With incidence rates as high as these and significant associated mortality and morbidity, it is no wonder that lung cancer is one of the main areas of research focused on cancer. Advances in targeted treatments and specialized irradiation protocols have allowed the treatment of more advanced cases. However, as the patient numbers grow, so does the need for cancer-preventive strategies. The present narrative review ...
Source: Current Medicinal Chemistry - February 19, 2024 Category: Chemistry Authors: Efstratios Athanasiou Savvas Papageorgiou Marianna Foteini Dafni Ioannis Kelesis Maria Vasileiou Theodora Tatsiou Vasiliki Kouveloglou Panagiotis Kanatas Ioannis Stouras Athanasios Gatsis Vasiliki Taxiarchoula Agiassoti Petros Nasimpian Dimitrios Dafnoudi Source Type: research
Polyphenol exposure of mothers and infants assessed by LC-MS/MS based biomonitoring in breast milk
In conclusion, the developed method was demonstrated to be fit-for-purpose to simultaneously (semi-) quantify a wide variety of polyphenols in breast milk. It also demonstrated that various polyphenols including their biotransformation products were present in breast milk and therefore likely transferred to infants where they might impact microbiome development and infant health.PMID:38363307 | DOI:10.1007/s00216-024-05179-y (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - February 16, 2024 Category: Chemistry Authors: Sabrina Berger Ian Oesterle Kolawole I Ayeni Chibundu N Ezekiel Annette Rompel Benedikt Warth Source Type: research
Polyphenol exposure of mothers and infants assessed by LC-MS/MS based biomonitoring in breast milk
In conclusion, the developed method was demonstrated to be fit-for-purpose to simultaneously (semi-) quantify a wide variety of polyphenols in breast milk. It also demonstrated that various polyphenols including their biotransformation products were present in breast milk and therefore likely transferred to infants where they might impact microbiome development and infant health.PMID:38363307 | DOI:10.1007/s00216-024-05179-y (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - February 16, 2024 Category: Chemistry Authors: Sabrina Berger Ian Oesterle Kolawole I Ayeni Chibundu N Ezekiel Annette Rompel Benedikt Warth Source Type: research
