Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research
Curr Issues Mol Biol. 2024 Mar 7;46(3):2166-2180. doi: 10.3390/cimb46030140.ABSTRACTThe purpose of this study was to evaluate the effect of genistein in nano, micro, and macro forms on the intensity of the DMBA-induced tumor process in rats and to understand the mechanisms of this action. The effect of genistein supplementation on the content of selected eicosanoids (HETEs, HODE, and HEPE) in the serum of rats was evaluated. The levels and expression of genes encoding various pro-inflammatory cytokines (IL-1, IL-6) and MMP-9 in the blood of rats were also investigated. The biological material for the study was blood obtain...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Karolina Bany ś Ma łgorzata Jelińska Ma łgorzata Wrzosek Dorota Skrajnowska Robert Wrzesie ń Wojciech Bielecki Barbara Bobrowska-Korczak Source Type: research
Phytocompounds targeting epigenetic modulations: an assessment in cancer
For centuries, plants have been serving as sources of potential therapeutic agents. In recent years, there has been a growing interest in investigating the effects of plant-derived compounds on epigenetic processes, a novel and captivating Frontier in the field of epigenetics research. Epigenetic changes encompass modifications to DNA, histones, and microRNAs that can influence gene expression. Aberrant epigenetic changes can perturb key cellular processes, including cell cycle control, intercellular communication, DNA repair, inflammation, stress response, and apoptosis. Such disruptions can contribute to cancer developme...
Source: Frontiers in Pharmacology - March 26, 2024 Category: Drugs & Pharmacology Source Type: research
Profiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation
ConclusionThe identification of bioactive molecules, such as genistein and SCFAs, capable of modulating anti-inflammatory signaling cascades in the stomach's gastric and neuroendocrine tissues can explain the reported biological effects in GAD and is supported by in vivo data. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - March 25, 2024 Category: Food Science Authors: Richard Ethier,
Arun Krishnamurthy,
Michael Jeffrey,
Thomas A. Tompkins Tags: Research Article Source Type: research
