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Study in mice finds dietary levels of genistein may adversely affect female fertility
(University of Illinois at Urbana-Champaign) A new study of mice by scientists at the University of Illinois raises concerns about the potential impact that long-term exposure to genistein prior to conception may have on fertility and pregnancy. The study was conducted by food science and human nutrition professor William G. Helferich, comparative biosciences professor Jodi A. Flaws, Illinois alumna Shreya Patel and animal sciences research specialist James A. Hartman. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 14, 2017 Category: International Medicine & Public Health Source Type: news

Breast cancer treatment may be enhanced by soy isoflavones
A study, published inCurrent Developments in Nutrition,found that the soy component, genistein, may slow the progress of breast cancer tumours.Medical News Today (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 1, 2017 Category: Endocrinology Source Type: news

Soy Isoflavones Inducing Overt Hypothyroidism Soy Isoflavones Inducing Overt Hypothyroidism
This case demonstrates that consuming certain foods containing soy isoflavones--in this case a health drink--can lead to severe hypothyroidism in persons with thyroid conditions.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 1, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

UA Cancer Center research team explores anti-breast cancer properties of soy
(University of Arizona Health Sciences) Genistein, a major compound in soy foods, might aid in the proper functioning of a gene that can malfunction to cause breast cancer. A UA Cancer Center team is exploring the gene's potential to treat a form of breast cancer and help prevent the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 30, 2017 Category: International Medicine & Public Health Source Type: news

How Soy Can Both Prevent Breast Cancer And Fuel Its Spread
To eat soy or not: That’s the question many U.S. women have been asking. Tofu, miso paste and other soybean-based foods are high-quality sources of protein that are low in calories and saturated fat. And studies have shown that they can help prevent cancer. Yet many doctors recommend that women who have, or are at risk of developing, a common form of breast cancer called estrogen-receptor-positive breast cancer avoid eating soybean-based foods because they contain compounds called isoflavones. Some studies suggest that isoflavones can mimic the hormone estrogen and encourage tumor growth. Now, in an animal study, res...
Source: Science - The Huffington Post - February 3, 2017 Category: Science Source Type: news

How Soy Can Both Prevent Breast Cancer And Fuel Its Spread
To eat soy or not: That’s the question many U.S. women have been asking. Tofu, miso paste and other soybean-based foods are high-quality sources of protein that are low in calories and saturated fat. And studies have shown that they can help prevent cancer. Yet many doctors recommend that women who have, or are at risk of developing, a common form of breast cancer called estrogen-receptor-positive breast cancer avoid eating soybean-based foods because they contain compounds called isoflavones. Some studies suggest that isoflavones can mimic the hormone estrogen and encourage tumor growth. Now, in an animal study, res...
Source: Healthy Living - The Huffington Post - February 3, 2017 Category: Consumer Health News Source Type: news

Soy Isoflavones Tied to Improved Metabolic Markers in PCOS Soy Isoflavones Tied to Improved Metabolic Markers in PCOS
Women with polycystic ovary syndrome may benefit from taking a soy supplement or drinking a cup of soy milk a day, a preliminary study suggests.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - August 4, 2016 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Soy may help protect women with PCOS from diabetes, heart disease
(The Endocrine Society) Women who have polycystic ovary syndrome -- a common cause of female infertility -- may be able to improve their metabolic and cardiovascular health by consuming soy isoflavones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology& Metabolism. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 4, 2016 Category: Global & Universal Source Type: news

Soy supplements, herbal remedies may reduce hot flashes
(Reuters Health) – Soy isoflavones in foods or supplements, and some herbal remedies may help reduce menopause symptoms like hot flashes and vaginal dryness, according to a review of 62 studies. (Source: Reuters: Health)
Source: Reuters: Health - June 21, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Soy shows promise as natural anti-microbial agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study. Soybean derivatives are already a mainstay in food products, such as cooking oils, cheeses, ice cream, margarine, food spreads, canned foods and baked goods. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 25, 2016 Category: Science Source Type: news

Soy shows promise as natural anti-microbial agent: Study
(University of Guelph) Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 25, 2016 Category: Biology Source Type: news

Soy Supplement Did Not Improve AsthmaSoy Supplement Did Not Improve Asthma
Soy isoflavones did not improve lung function or clinical outcomes in patients older than 12 years with poorly controlled asthma in a randomized clinical trial. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 27, 2015 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Mitochondriotropic Nanoemulsified Genistein-Loaded Vehicles for Cancer Therapy
Genistein (Gen), a major soy isoflavone, produces extensive pro-apoptotic anticancer effects, mediated predominantly via induction of mitochondrial damage. Based on several biophysical model criteria, our rational assumptions for the native mitochondrial selectivity of Gen allowed its design as a cationic lipid-based nanocarrier (NC) system. Proof-of-concept nano-formulations, lipidic micelles (Mic), and nanoemulsions (NEs) incorporated Gen, which serves as therapeutic and targeting moieties, specific for mitochondria. Our in vitro experimental data demonstrated superior physicochemical properties and significant cytotoxic...
Source: Springer protocols feed by Pharmacology/Toxicology - February 5, 2015 Category: Drugs & Pharmacology Source Type: news

Soy Isoflavones: No Evidence of Endometrial Harm at 3 YearsSoy Isoflavones: No Evidence of Endometrial Harm at 3 Years
A study that found soy isoflavone supplements ineffective in preventing bone loss now shows that at least they do not appear harmful over the long term. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 19, 2014 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Genistein in soybeans may Inhibit HIV Infection
A compound found in soybeans may become an effective HIV treatment without the drug resistance issues faced by current therapies, according to new research by George Mason University researchers. It's in the early stages, but genistein, derived from soybeans and other plants, shows promise in inhibiting the HIV infection, says Yuntao Wu, a professor with the George Mason-based National Center for Biodefense and Infectious Diseases and the Department of Molecular and Microbiology. Still, that doesn't mean people should begin eating large amounts of soy products... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 31, 2013 Category: Consumer Health News Tags: HIV / AIDS Source Type: news

Are SOYA BEANS the key to wrinkle-free skin? Hormone in the vegetable can keep us looking youthful, say scientists
Genistein, a natural plant-hormone in soya, has been found to boost the production of collagen, the protein which gives skin its elasticity, according to the that depletes with age, according to the cosmetic firm Swisscode. (Source: the Mail online | Health)
Source: the Mail online | Health - April 22, 2013 Category: Consumer Health News Source Type: news

GCP Therapy May Extend Life Expectancy Of Prostate Cancer Patients With Low Response To Androgen-Deprivation Therapy
A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found. Men with prostate cancer that has spread to other parts of the body, known as metastatic cancer, and who have had their testosterone lowered with drug therapy are most likely to benefit. The study, recently published in Endocrine-Related Cancer, was conducted in prostate cancer cells and in mice... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 24, 2013 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

GCP Could Lengthen Life Expectancy Of Prostate Cancer Patients
The life expectancy of some prostate cancer patients could be lengthened with a natural, non-toxic substance called genistein-combined polysaccharide (GCP). The finding came from a new study on prostate cancer cells and mice conducted by researchers from University of California, Davis, and was published in Endocrine-Related Cancer. The men who have the highest probability to benefit from GCP are those with metastatic prostate cancer - cancer that has spread to other parts of the body - and have already used drug therapy to lower their testosterone levels... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 23, 2013 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Mushroom-supplemented soybean extract shows therapeutic promise for advanced prostate cancer
(University of California - Davis Health System) A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2013 Category: Global & Universal Source Type: news

Increasing effectiveness of androgen deprivation
Mooso et al. showed that Filamin A (FlnA) nuclear localisation induced apoptosis in castration-resistant prostate cancer (CRPC) cells during androgen deprivation therapy (ADT). The natural product genistein-combined polysaccharide (GCP) had a similar effect, by inducing FlnA cleavage and nuclear localisation. In a mouse model of prostate cancer recurrence, GCP, but not vehicle, impeded relapse following castration. These results demonstrate the efficacy of GCP in promoting FlnA nuclear localisation in prostate cancer. Mooso et al. (2013) Endocrine-Related Cancer 19, 759–777. Read the full article at DOI: 10.1530/ERC...
Source: Society for Endocrinology - January 8, 2013 Category: Endocrinology Source Type: news