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Mpox-associated supraglottitis in an immunocompetent, reportedly sexually abstinent child
Proc (Bayl Univ Med Cent). 2024 Feb 29;37(3):482-484. doi: 10.1080/08998280.2024.2314408. eCollection 2024.ABSTRACTMpox is a double-stranded DNA virus of the Orthopoxvirus genus related to smallpox virus endemic to Africa with more than 16,000 cases reported in nonendemic countries in 2022. Classically associated with adult men who have sex with men (MSM), Mpox was once labeled a public health emergency by the World Health Organization as concerning to the general population. Supraglottitis is a rare complication of Mpox that is underreported in the literature and presents a potential airway emergency. Prompt identificatio...
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Matthew Mitchell Mopileola Tomi Adewumi Lauren Welby Berra Randall Holdgraf Source Type: research

Viruses, Vol. 16, Pages 620: Antibodies Induced by Smallpox Vaccination after at Least 45 Years Cross-React with and In Vitro Neutralize Mpox Virus: A Role for Polyclonal B Cell Activation?
Conclusions: ELISA and WB performed using supernatant of VV- or MPXV-infected cells are suitable to identify individuals vaccinated against smallpox at more than 45 years from immunization and individuals convalescing from a recent MPXV infection. ELISA and WB results show a good correlation with PRNT. Data confirm that a smallpox vaccination induces a long-lasting memory in terms of specific IgG and that antibodies raised against VV may neutralize MPXV in vitro. Finally, higher titers of VV-specific antibodies and higher frequency of VV-specific memory T cells in LTBI individuals suggest a role of polyclonal non-specific ...
Source: Viruses - April 17, 2024 Category: Virology Authors: Sabrina Mariotti Giulietta Venturi Maria Vincenza Chiantore Raffaela Teloni Riccardo De Santis Antonello Amendola Claudia Fortuna Giulia Marsili Giorgia Grilli Maria Stella Lia Seble Tekle Kiros Filippo Lagi Alessandro Bartoloni Angelo Iacobino Raffaele C Tags: Article Source Type: research

In Commemoration of Dr. Mostafa Pourtaghva Shahrestani, a Pioneer in Infectious Disease Research
Arch Iran Med. 2024 Feb 1;27(2):105-109. doi: 10.34172/aim.2024.16.ABSTRACTIt is important to honor the contributions of scientific leaders who have dedicated their lives to advancing knowledge and serving their country. One way is to document their experiences and personalities in a documentary format, which can serve as a historical record and an inspiration for future generations. Dr. Mostafa Pourtaghva Shahrestani, a renowned physician and specialist in infectious diseases and tropical medicine, has made significant contributions to public health in Iran. He has played a crucial role in controlling infectious diseases ...
Source: Archives of Iranian Medicine - April 15, 2024 Category: Middle East Health Authors: Fatemeh Bardestani Mohammad Ali Rad Mohammad Hossein Azizi Mohammad Mehdi Gouya Ehsan Mostafavi Source Type: research

Vaccination, Dispossession, and the Indigenous Interior
This article explores a poorly understood smallpox vaccination campaign targeting Native Americans in the 1830s. While previous scholars have addressed the motivations of U.S. officials in launching the campaign, the author focuses on Indigenous people's interest in disease prevention and their reception of American physicians and vaccine technology across a broad swath of North America. Resistance to vaccination was not uncommon among Native people, yet many were open to the new form of preventive medicine, including some who sought it out and others who demanded it from the government. Departing from a scholarly consensu...
Source: Bulletin of the History of Medicine - April 8, 2024 Category: History of Medicine Authors: Seth Archer Source Type: research