Evaluating the Human Immune Response to the JYNNEOS Vaccine
Conditions: Vaccinia; Virus Diseases Interventions: Biological: JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection; Procedure: Phlebotomy; Procedure: Research bronchoscopy; Procedure: Skin punch biopsy; Procedure: Bone marrow aspiration Sponsors: Washington University School of Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials
Study of the Safety, Tolerability, Pharmacokinetics of NIOCH-14 in Volunteers Aged 18-50 Years
Conditions: Smallpox; Monkeypox; Cowpox; Vaccinia Virus Infection Interventions: Drug: NIOCH-14, 200 mg capsule: 1 capsule (200 mg) of NIOCH-14 once orally; Drug: NIOCH-14, 200 mg capsule: 3 capsules (200 mg each) of NIOCH-14 once orally. (Total 600 mg NIOCH-14 per day); Drug: NIOCH-14, 200 mg capsule: 6 capsules (200 mg each) of NIOCH-14 per day orally. (Total 1200 mg NIOCH-14 per day); Drug: NIOCH-14, 200 mg capsule: 1 capsule (200 mg) of NIOCH-14 a day orally for 6 days; Drug: NIOCH-14, 200 mg capsule: 3 capsules (200 mg each) of NIOCH-14 a day orally for 6 days. (Total 600 mg NIOCH-14 per d...
Source: ClinicalTrials.gov - August 4, 2023 Category: Research Source Type: clinical trials
Study Evaluating the Bioequivalence of Brincidofovir Form H and Form II Tablets in Healthy Adults
Condition: Smallpox Intervention: Drug: Brincidofovir Sponsor: Emergent BioSolutions Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 7, 2023 Category: Research Source Type: clinical trials
