Effects of Sleep Hygiene on Sleep Disturbance in Patients with Parkinsonism
Background: Patients with Parkinsonism often encounter various sleep-related issues, including insomnia, sleep fragmentation, REM sleep behavior disorder(RBD), Restless Legs Syndrome(RLS), Excessive Daytime Sleepiness(EDS), and circadian rhythm disruptions. However, to date, the focus has primarily centered on alleviating symptoms through medical interventions, with limited research addressing the enhancement of sleep disturbances through sleep hygiene practices. We conducted a cross-sectional study to examine the impact of sleep hygiene on sleep disturbance in Parkinsonism patients. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: J.Y. Yun, C.Y. Lee, H. Kim Source Type: research
Targeting sedentary behavior decreases depressive symptoms and improves sleep in people with Parkinson ’s Disease
Background: Physical Therapy (PT) and regular exercise are an integral part of the management of Parkinson's Disease (PD). Exercise is also known to have a mitigating effect on depressive symptoms. There is increasing evidence that decreasing sedentary behavior is also a valuable tool to manage PD symptoms. We looked at the effect of decreasing sedentary behavior on depressive symptoms in PD by offering an opportunity to replace sedentary behavior with slow paced standing and stepping behavior in the home environment. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: M. van Emde Boas, C. Pongmala, A. Griggs, G. Carli, N.I. Bohnen Source Type: research
Effects of Continuous Subcutaneous Infusion of Foslevodopa/Foscarbidopa on Sleep Dysfunction in People With Parkinson's
Background: The study objective was to assess whether 24-hour/day continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (LDp/CDp) improves Parkinson ’s Disease Sleep Scale-2 (PDSS-2) subdomains in people with Parkinson’s (PwP). The PDSS-2 provides a Total Score (TS) and subdomain scores for: Motor Symptoms at Night (MS), Parkinson’s Disease Symptoms at Night (PDS), and Disturbed Sleep (DS). A double-blind 12-week phase 3 trial of LDp/CDp C SCI versus levodopa-carbidopa immediate-release (LD/CD-IR) oral tablets (NCT04380142) suggested improvements in the intention-to-treat (ITT) population PDSS-2 TS. (So...
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: R. Hauser, B. Bergmans, I. Malaty, D. Cobb, J. Homola, L. Bergmann, R. Gupta, J. Jia, M. Shah, K.R. Chaudhuri Source Type: research
Improvement of non-motor symptoms with NE3107 adjunctive to Carbidopa / Levodopa in patients with Parkinson`s disease: A Phase 2A, placebo-controlled study
Background: NE3107 is an oral, blood-brain barrier –permeable, anti-inflammatory insulin-sensitizer that binds extracellular signal-regulated kinase and inhibits inflammatory nuclear factor kappa B and tumor necrosis factor alpha (TNF-α) signaling. Inflammation, particularly TNF-α, may have a role in sleep regulation, fatigue, and restless legs symptoms. Therefore, we evaluated the effects of NE3107 treatment on non-motor symptoms (NMS) in patients with carbidopa/levodopa (C/L)-treated Parkinson’s disease (PD) experiencing motor fluctuations. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: J. Palumbo, C. Reading, C. Ahlem, N. Osman, J. Zhang, J. Aldred, R. Rodriguez, E. Rivera-Rivera, S. Isaacson, R. Kumar, A. Ellenbogen, A. Lang Source Type: research
Opicapone Effect on Sleep Disorders in Fluctuating Parkinson ’s Disease Patients: Findings from the OASIS Trial
Background: Motor fluctuations (MF) and associated sleep disorders are common in Parkinson ’s disease (PD) patients receiving levodopa/dopa decarboxylase inhibitors, negatively affecting their quality of life. Opicapone (OPC) proved to be effective in reducing end-of-dose MF in patients with PD. The OASIS study evaluated OPC’s effects on sleep disorders in PD patients with MF. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: J.J. Ferreira, M.F. Gago, R. Costa, M.M.F. Fonseca, J. Almeida, J.-F. Rocha, J. Holenz, C. Trenkwalder Source Type: research
Late-onset narcolepsy type 1 comorbid with anti-IgLON5 disease in an older male patient
Journal of Clinical Sleep Medicine,Volume 20, Issue 5, Page 829-832, May 2024. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - May 1, 2024 Category: Sleep Medicine Authors: Xiaoli Wang
Na Yuan
Xinbo Zhang
Yonghong Liu
Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi ’an, China Source Type: research
Treatment of REM sleep behavior disorder with trazodone: report of 3 cases
Journal of Clinical Sleep Medicine,Volume 20, Issue 5, Page 821-823, May 2024. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - May 1, 2024 Category: Sleep Medicine Authors: Jorden Barrow
Martina Vendrame
1Lehigh Valley Fleming Neuroscience Institute, Lehigh Valley Health Network, Allentown, Pennsylvania
2Morsani College of Medicine, University of South Florida, Tampa, Florida Source Type: research
Cannabidiol for moderate –severe insomnia: a randomized controlled pilot trial of 150 mg of nightly dosing
Journal of Clinical Sleep Medicine,Volume 20, Issue 5, Page 753-763, May 2024. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - May 1, 2024 Category: Sleep Medicine Authors: Andrea J. Narayan
Luke A. Downey
Sarah Rose
Lauren Di Natale
Amie C. Hayley
1Centre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, Australia
2Institute for Breathing and Sleep, Austin Hospital, Melbourne, Australia Source Type: research
Association of preadmission insomnia symptoms with objective in-hospital sleep and clinical outcomes among hospitalized patients
Journal of Clinical Sleep Medicine,Volume 20, Issue 5, Page 681-687, May 2024. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - May 1, 2024 Category: Sleep Medicine Authors: Julie M. Neborak
Valerie G. Press
William F. Parker
Juan C. Rojas
Max Byron
Swati Goyal
David O. Meltzer
Babak Mokhlesi
Vineet M. Arora
1Rush University Medical Center, Chicago, Illinois
2University of Chicago Hospitals, Chicago, Illinois
3Northwestern Un Source Type: research
Prevalence of pulmonary hypertension in obstructive sleep apnea and its relation to disease severity
Journal of Clinical Sleep Medicine,Volume 20, Issue 5, Page 675-680, May 2024. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - May 1, 2024 Category: Sleep Medicine Authors: Ian Milligan
Anna Kate Shaw
Roberta Leu
Usama Kanaan
Erik Michelfelder
1Children ’s Healthcare of Atlanta, Atlanta, Georgia
2Department of Pediatric Cardiology, Emory University, Atlanta, Georgia
3Department of Pediatric Sleep Medicine, Emory University Source Type: research
The moderating role of conscientiousness in the temporal association of stress on sleep
This study examined whether daytime stress predicts sleep the following night, and the moderating role of neuroticism and conscientiousness in this relationship. To introduce stress variability in natural daily stressors, we measured college students (N = 92) during exams (e.g. high academic stress) and at the start of new course period (e.g. low academic stress). Both objective (actigraphy) and subjective sleep, and daily self-reported stress, were measured for 14 days and personality traits once. Reported daily stress was significantly higher in the exam period compared with baseline, suggesting that our natural manipula...
Source: Journal of Sleep Research - April 30, 2024 Category: Sleep Medicine Authors: Conny W E M Quaedflieg Camilla Bossi Jessica Bruijel Source Type: research
Insomnia and risk of mortality in older adults
J Sleep Res. 2024 Apr 29:e14229. doi: 10.1111/jsr.14229. Online ahead of print.ABSTRACTExisting evidence linking insomnia to all-cause mortality in older individuals remains inconclusive. We conducted a retrospective study of a large cohort of veterans aged 65-80 years old identified from the Corporate Data Warehouse, a large data repository derived from the Veterans Health Administration integrated medical records. Veterans' enrollees with and without International Classification of Diseases, Ninth and Tenth Revision, codes corresponding to insomnia diagnosis between 1 January 2010 and 30 March 2019 were assessed for elig...
Source: Journal of Sleep Research - April 30, 2024 Category: Sleep Medicine Authors: Yolanda Lawson Gregory E Wilding Ali A El-Solh Source Type: research
Fever-induced acute sleep terrors in children and adolescents following SARS-CoV-2 infection
CONCLUSION: SARS-CoV-2 infection may precipitate acute sleep terrors in children and adolescents. The course of these sleep terrors is generally benign, with all patients achieving spontaneous complete remission over time.PMID:38689200 | DOI:10.1007/s11325-024-03038-9 (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 30, 2024 Category: Sleep Medicine Authors: Xiaoli Wang Na Yuan Jiang Zhu Bi Wang Wenjuan Zhang Yonghong Liu Source Type: research
Identifying and Mitigating Sound Sources to Enhance Patients' Sleep
Am J Crit Care. 2024 May 1;33(3):210. doi: 10.4037/ajcc2024102.NO ABSTRACTPMID:38688849 | DOI:10.4037/ajcc2024102 (Source: American Journal of Critical Care)
Source: American Journal of Critical Care - April 30, 2024 Category: Nursing Authors: Meredith Padilla Source Type: research