Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)
The objective of this funding opportunity is to support non-pharmacological interventions to promote sleep health, reduce sleep health disparities, and examine sleep as a modifiable factor to reduce health disparities for other health outcomes among populations that experience health disparities. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 19, 2024 Category: Research Source Type: funding
Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
Funding Opportunity RFA-MH-25-130 from the NIH Guide for Grants and Contracts. NIMH seeks applications for pilot research to adapt, optimize, and test empirically supported behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. Pilot trials should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach in real world settings, and to conduct a preliminary test of the interventions impact on target mechanisms and sleep and mental health outcomes, and to obtain preliminary dat...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 17, 2024 Category: Research Source Type: funding
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This NOFO will ut...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 2, 2024 Category: Research Source Type: funding
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be establis...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 1, 2024 Category: Research Source Type: funding
Mechanisms of Cognitive Fluctuations in ADRD Populations (R01 - Clinical Trial Optional)
Funding Opportunity RFA-NS-25-014 from the NIH Guide for Grants and Contracts. "Fluctuating cognition can occur in many types of dementia and is a core clinical feature of Dementia with Lewy Bodies. Cognitive fluctuations can last from seconds to days, are unpredictable (e.g., do not just occur in the evenings, as with sun-downing), and are associated with poor daily functioning for the patient. A number of small studies have suggested that cognitive fluctuations in subjects with dementia may be related to epileptiform discharges and impaired oscillatory activity on EEG, but it is not clear that these are the only facto...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 18, 2024 Category: Research Source Type: funding
Notice of NICHD Withdrawal from Participation in NOT-HL-23-117 "Notice of Special Interest (NOSI): Palliative Care in the Care Continuum among Persons with Serious Heart, Lung, Blood and Sleep (HLBS) Diseases and their Caregivers"
Notice NOT-HD-23-037 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 24, 2023 Category: Research Source Type: funding
NHLBI Program Project Applications (P01 Clinical Trials Optional)
Funding Opportunity PAR-24-065 from the NIH Guide for Grants and Contracts. The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 20, 2023 Category: Research Source Type: funding
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
Funding Opportunity PAR-24-049 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this NOFO will support research projects that are designed to provide results that will be sufficient to inform the fu...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 3, 2023 Category: Research Source Type: funding
Notice of Special Interest (NOSI): Palliative Care in the Care Continuum among Persons with Serious Heart, Lung, Blood and Sleep (HLBS) Diseases and their Caregivers
Notice NOT-HL-23-117 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 19, 2023 Category: Research Source Type: funding
Request for Information (RFI): Exploring the role of Generative AI in enhancing the use of Big Data in Heart, Lung, Blood, and Sleep (HLBS) research.
Notice NOT-HL-23-097 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 3, 2023 Category: Research Source Type: funding
Validating digital health technologies for monitoring biomarkers in ADRD clinical trials (R61/R33 - Clinical Trials Optional)
Funding Opportunity RFA-NS-24-026 from the NIH Guide for Grants and Contracts. The goal of this RFA is to enable partnerships between academics and companies that make wearable devices to validate their digital health technologies (DHTs) as digital monitoring biomarkers in ADRD populations. Applications will be required to optimize their DHTs in diverse patient populations from two or more early stage clinically diagnosed ADRD. Studies must demonstrate the accuracy of the digital markers to differentiate clinically meaningful features (such as sleep stage) and establish the longitudinal relationship between the features...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 1, 2023 Category: Research Source Type: funding
The Role of Sleep Deficiency in Persons with Type 1 Diabetes: Sleep, Glycemic Control, and Cardiovascular Risk (R34 Clinical Trial Optional)
Funding Opportunity RFA-HL-24-009 from the NIH Guide for Grants and Contracts. This NOFO will support preliminary studies aimed to obtain information necessary to guide the design of a full randomized control trial to test whether sleep and circadian targeted interventions improve the clinical course and treatment outcomes in individuals with Type 1 Diabetes (T1D). Applications should focus on pilot studies to inform practical and potentially sustainable strategies to improve processes of care and cardiometabolic health outcomes in individuals with T1D. The scope of research for this NOFO includes a range of feasibility...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 20, 2023 Category: Research Source Type: funding
The Role of Sleep Deficiency in Persons with Type 1 Diabetes: Sleep, Glycemic Control, and Cardiovascular Risk (R01 Clinical Trial Optional)
Funding Opportunity RFA-HL-24-008 from the NIH Guide for Grants and Contracts. The purpose of this NOFO is to elucidate the contribution of sleep deficiency and circadian disruption to metabolic and cardiovascular pathobiology, disease trajectory, and treatment response in individuals living with Type 1 Diabetes (T1D). The RFA will support clinically relevant, mechanism focused research on the interface between sleep, circadian rhythms biology, T1D and cardiovascular disease. Multi-disciplinary teams bridging sleep/circadian, diabetes, and cardiovascular research are encouraged. Proposed research should be relevant to t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 20, 2023 Category: Research Source Type: funding
Mechanistic Studies to Investigate the Interrelationship Between Sleep and/or Circadian Rhythms and Substance Use Disorders (R01 Basic Experimental Studies with Humans Required)
Funding Opportunity RFA-DA-24-021 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support basic science experimental studies involving humans that expand our knowledge of theinterrelationships between sleep/circadian rhythms and substance use disorders (SUDs). These mechanistic studies will offer insights into the fundamental processes that link SUDs to disorders of sleep/circadian rhythm and vice-versa, and may also have implications for managing risks associated with developing SUDs and/or identifying new targets for prevention and therapeutics. (Source: NIH ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 18, 2023 Category: Research Source Type: funding
Mechanistic Studies to Investigate the Interrelationship Between Sleep and/or Circadian Rhythms and Substance Use Disorders (R01 Clinical Trials Not Allowed)
Funding Opportunity RFA-DA-24-020 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support basic science experimental studies that expand our knowledge of theinterrelationships between sleep/circadian rhythms and substance use disorders (SUDs). These mechanistic studies will offer insights into the fundamental processes that link SUDs to disorders of sleep/circadian rhythm and vice-versa, and may also have implications for managing risks associated with developing SUDs and/or identifying new targets for prevention and therapeutics. (Source: NIH Funding Opportuni...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 18, 2023 Category: Research Source Type: funding
