Very Young Children Exposed to Anesthesia May Be at Higher Risk of Childhood Bipolar Disorder
Infants and toddlers who are exposed to general anesthesia may be at increased risk for bipolar disorder later in childhood compared with infants and toddlers who are not exposed, according to areport inSchizophrenia Bulletin. The association remained after adjusting for other childhood comorbidities and parental psychiatric diagnoses.“In the context of pediatric care, it is essential to recognize the substantial perioperative trauma experienced by children, both physically and psychologically,” wrote Mingyang Sun, M.D., of the People’s Hospital of Zhenghzou University in Henan, China, and colleagues. “Emerging evi...
Source: Psychiatr News - April 24, 2024 Category: Psychiatry Tags: anesthesia bipolar disorder children general anesthesia hospital risk factor sevoflurane Taiwan toddlers Source Type: research
Advances in pediatric anesthesia services over the past 10 years in French-speaking sub-Saharan Africa
CONCLUSION: Progress have been made over the last 10 years in French-speaking SSA to improve infrastructures, human resources, education, medications, and equipment for pediatric anesthesia in French-speaking SSA. However, major efforts must be continued. Standards adapted to the local context should be formulated.PMID:38655778 | DOI:10.1111/pan.14904 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - April 24, 2024 Category: Anesthesiology Authors: K élan Bertille Ki Fatou Fleur Sanou Marie Ndoye Diop Ismael Guibla Mamadou Traore Joseph Donamou Moustapha Mangane Yvette Kabre Hadjara Daddy Buhendwa Jean Paul Cikwanine Hamza Sama Joseph Akodjenou Adjougoulta Koboy Do-A-Nduo Bonte Junete Metogo Mbengo Source Type: research
The incidences of nausea and vomiting after general anesthesia with remimazolam versus sevoflurane: a prospective randomized controlled trial
CONCLUSIONS: Compared to sevoflurane, opting for remimazolam as an intraoperative hypnotic may decrease the incidence of PONV and reduce antiemetic use for 24 h after laparoscopic surgery.PMID:38637272 | DOI:10.4097/kja.23939 (Source: Korean Journal of Anesthesiology)
Source: Korean Journal of Anesthesiology - April 18, 2024 Category: Anesthesiology Authors: Yeong Min Yoo Jae Hong Park Ki Hwa Lee Ah Hyeon Yi Tae Kyun Kim Source Type: research
Choice of anesthesia technique is associated with earlier hospital discharge and reduced costs after transcatheter transfemoral aortic valve implantation
CONCLUSIONS: Advancements in TAVI technologies, conscious sedation and a collaborative, multidisciplinary team approach reduces overall length of hospital stay and procedure costs.PMID:38617787 | PMC:PMC11009576 | DOI:10.21037/jtd-23-1739 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Carla Luzzi David Orlov Karen Foley Eric Horlick Mark Osten Robert James Cusimano George Djaiani Source Type: research
Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency
In this study, we used molecular docking, dual whole-cell patch-clamp, and Western blotting to investigate the impact of connexin phosphorylation on GJ chemical gating by α-pinene and other GJ inhibitors (octanol, carbenoxolone, mefloquine, intracellular pH, glycyrrhetinic acid, and sevoflurane) in HeLa cells expressing exogenous Cx43 (full length and truncated at amino acid 258) and other connexins typical of heart and/or nervous system (Cx36, Cx40, Cx45, and Cx47), and in cells expressing endogenous Cx43 (Novikoff and U-87). We found that Ca2+-regulated kinases, such as Ca2+/calmodulin-dependent kinase II, atypical prot...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 9, 2024 Category: Drugs & Pharmacology Authors: Rokas Mickus Vytautas Ra škevičius Ieva Sarapinien ė Valeryia Mikalayeva Rytis Prekeris Vytenis Arvydas Skeberdis Source Type: research
Influencing Factors of Delirium during Recovery in Urological Postoperative Patients Undergoing Sevoflurane Anaesthesia
CONCLUSIONS: Age, history of diabetes, operation time, ASA classification and sevoflurane inhalation concentration are the influencing factors.PMID:38583014 | DOI:10.56434/j.arch.esp.urol.20247702.27 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Chuan He Yuhong Sun Yu Meng Huanli Qian Source Type: research
Effects of sevoflurane on lung alveolar epithelial wound healing and survival in a sterile in vitro model of acute respiratory distress syndrome
In this study, we investigated the effects of sevoflurane on lung injury in cultured human carcinoma-derived lung alveolar epithelial (A549) cells. We found that sevoflurane was associated with improved wound healing after exposure to inflammatory cytokines, with preserved cell proliferation but no effect on cell migration properties. Sevoflurane exposure was also associated with enhanced cell viability and active autophagy in A549 cells exposed to cytokines. These findings suggest that sevoflurane may have beneficial effects on lung epithelial injury by promoting alveolar epithelial wound healing and by influencing the su...
Source: Experimental Cell Research - April 7, 2024 Category: Cytology Authors: Florian Loubet C édric Robert Charlotte Leclaire Camille Theilli ère C écile Saint-Béat Woodys Lenga Ma Bonda Ruoyang Zhai R égine Minet-Quinard Corinne Belville Loic Blanchon Vincent Sapin Marc Garnier Matthieu Jabaudon Source Type: research
Influencing Factors of Delirium during Recovery in Urological Postoperative Patients Undergoing Sevoflurane Anaesthesia
CONCLUSIONS: Age, history of diabetes, operation time, ASA classification and sevoflurane inhalation concentration are the influencing factors.PMID:38583014 | DOI:10.56434/j.arch.esp.urol.20247702.27 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Chuan He Yuhong Sun Yu Meng Huanli Qian Source Type: research
