Choice of anesthesia technique is associated with earlier hospital discharge and reduced costs after transcatheter transfemoral aortic valve implantation
CONCLUSIONS: Advancements in TAVI technologies, conscious sedation and a collaborative, multidisciplinary team approach reduces overall length of hospital stay and procedure costs.PMID:38617787 | PMC:PMC11009576 | DOI:10.21037/jtd-23-1739 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Carla Luzzi David Orlov Karen Foley Eric Horlick Mark Osten Robert James Cusimano George Djaiani Source Type: research
Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency
In this study, we used molecular docking, dual whole-cell patch-clamp, and Western blotting to investigate the impact of connexin phosphorylation on GJ chemical gating by α-pinene and other GJ inhibitors (octanol, carbenoxolone, mefloquine, intracellular pH, glycyrrhetinic acid, and sevoflurane) in HeLa cells expressing exogenous Cx43 (full length and truncated at amino acid 258) and other connexins typical of heart and/or nervous system (Cx36, Cx40, Cx45, and Cx47), and in cells expressing endogenous Cx43 (Novikoff and U-87). We found that Ca2+-regulated kinases, such as Ca2+/calmodulin-dependent kinase II, atypical prot...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 9, 2024 Category: Drugs & Pharmacology Authors: Rokas Mickus Vytautas Ra škevičius Ieva Sarapinien ė Valeryia Mikalayeva Rytis Prekeris Vytenis Arvydas Skeberdis Source Type: research
Influencing Factors of Delirium during Recovery in Urological Postoperative Patients Undergoing Sevoflurane Anaesthesia
CONCLUSIONS: Age, history of diabetes, operation time, ASA classification and sevoflurane inhalation concentration are the influencing factors.PMID:38583014 | DOI:10.56434/j.arch.esp.urol.20247702.27 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Chuan He Yuhong Sun Yu Meng Huanli Qian Source Type: research
Effects of sevoflurane on lung alveolar epithelial wound healing and survival in a sterile in vitro model of acute respiratory distress syndrome
In this study, we investigated the effects of sevoflurane on lung injury in cultured human carcinoma-derived lung alveolar epithelial (A549) cells. We found that sevoflurane was associated with improved wound healing after exposure to inflammatory cytokines, with preserved cell proliferation but no effect on cell migration properties. Sevoflurane exposure was also associated with enhanced cell viability and active autophagy in A549 cells exposed to cytokines. These findings suggest that sevoflurane may have beneficial effects on lung epithelial injury by promoting alveolar epithelial wound healing and by influencing the su...
Source: Experimental Cell Research - April 7, 2024 Category: Cytology Authors: Florian Loubet C édric Robert Charlotte Leclaire Camille Theilli ère C écile Saint-Béat Woodys Lenga Ma Bonda Ruoyang Zhai R égine Minet-Quinard Corinne Belville Loic Blanchon Vincent Sapin Marc Garnier Matthieu Jabaudon Source Type: research
Influencing Factors of Delirium during Recovery in Urological Postoperative Patients Undergoing Sevoflurane Anaesthesia
CONCLUSIONS: Age, history of diabetes, operation time, ASA classification and sevoflurane inhalation concentration are the influencing factors.PMID:38583014 | DOI:10.56434/j.arch.esp.urol.20247702.27 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Chuan He Yuhong Sun Yu Meng Huanli Qian Source Type: research
