Sirtuin 3 (SIRT3) improves sevoflurane-induced postoperative cognitive impairment by regulating mitochondrial oxidative stress
Cell Mol Biol (Noisy-le-grand). 2024 Feb 29;70(2):62-66. doi: 10.14715/cmb/2024.70.2.9.ABSTRACTOne of the most prevalent co-operative disorders is postoperative cognitive dysfunction (POCD), however, its pathogenesis remains unclear. Thus, the aim of this work was to evaluate SIRT3's impact on cognitive decline in aged mice under anesthesia. Adeno-associated virus SIRT3 vector (AAV-SIRT3) or empty vector (AAV-VEH) was injected into the hippocampal region of aged mice after sevoflurane induction in order to upregulate the expression of SIRT3. The expression levels of SIRT3, pro-inflammatory cytokines, and apoptotic factors ...
Source: Mol Biol Cell - March 2, 2024 Category: Molecular Biology Authors: Changzong Dai Changquan Fu Zhiguo Yi Xiaohong Guan Jiandong Deng Source Type: research
Application of remimazolam-0.6% sevoflurane anesthesia for flash visual evoked potential monitoring during pituitary adenoma resection: a non-inferiority randomized controlled trial
Flash visual evoked potential (FVEP) is a critical method for monitoring intraoperative visual function during neurosurgery. A new benzodiazepine drug called remimazolam has recently been used for general anes... (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - February 29, 2024 Category: Anesthesiology Authors: Fu Shi, Ranran Tang, Xiangrong Du, Xin Li and Guisheng Wu Tags: Research Source Type: research
Sevoflurane Alters Serum Metabolites in Elders and Aging Mice and Increases Inflammation in Hippocampus
CONCLUSION: Sevoflurane-induced alterations in serum metabolites in both elderly patients and aging mice, subsequently contributing to increased inflammation in the hippocampus.PMID:38415263 | PMC:PMC10898602 | DOI:10.2147/JIR.S448959 (Source: Cell Research)
Source: Cell Research - February 28, 2024 Category: Cytology Authors: Tingting Wang Xia Wu Xiaoli Zhao Jiaqi Li Jian Yu Maozheng Sheng Mingyuan Gao Yutang Cao Jiawen Wang Xiaozhen Guo Kai Zeng Source Type: research
Sevoflurane preconditioning in living liver donation is associated with better initial graft function after pediatric transplantation: a retrospective study
ConclusionSignificantly fewer children who received a graft from a donor in whom only sevoflurane was used to maintain anesthesia developed IPGF. Although additional research is needed, this preconditioning strategy may provide an option to prevent IPGF after living liver donation. (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 28, 2024 Category: Surgery Source Type: research
Effect of Sevoflurane Anesthesia on Diastolic Function: A Prospective Observational Study
CONCLUSIONS: In this study, echocardiographic parameters of diastolic function, including septal e', E, E/A, and DT, improved with sevoflurane anesthesia in patients with preexisting diastolic dysfunction, but remained unchanged in patients with normal diastolic function.PMID:38412113 | DOI:10.1213/ANE.0000000000006924 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 27, 2024 Category: Anesthesiology Authors: Sang Hyun Lee Hyun Joo Ahn Gyeong Min Kim MiKyung Yang Jie Ae Kim Sangmin M Lee Burn Young Heo Ji Won Choi Jin Young Lee Heejoon Jeong Jeayoun Kim Source Type: research
Effect of Sevoflurane Anesthesia on Diastolic Function: A Prospective Observational Study
CONCLUSIONS: In this study, echocardiographic parameters of diastolic function, including septal e', E, E/A, and DT, improved with sevoflurane anesthesia in patients with preexisting diastolic dysfunction, but remained unchanged in patients with normal diastolic function.PMID:38412113 | DOI:10.1213/ANE.0000000000006924 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 27, 2024 Category: Anesthesiology Authors: Sang Hyun Lee Hyun Joo Ahn Gyeong Min Kim MiKyung Yang Jie Ae Kim Sangmin M Lee Burn Young Heo Ji Won Choi Jin Young Lee Heejoon Jeong Jeayoun Kim Source Type: research
Sevoflurane Alters Serum Metabolites in Elders and Aging Mice and Increases Inflammation in Hippocampus
(Source: Journal of Inflammation Research)
Source: Journal of Inflammation Research - February 23, 2024 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Retraction Note: Effect of apoptosis in neural stem cells treated with sevoflurane
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12871-024-02448-2. (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - February 23, 2024 Category: Anesthesiology Authors: Jianlei Qiu, Pengcai Shi, Wude Mao, Yuyi Zhao, Wenshuai Liu and Yuelan Wang Tags: Retraction Note Source Type: research
Sevoflurane exerts antidepressant-like effects via the BDNF-TrkB pathway
In conclusion, this study provides evidence supporting the notion that sevoflurane exerts its antidepressant-like effect via the BDNF-TrkB signaling pathway.PMID:38387696 | DOI:10.1016/j.bbr.2024.114918 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - February 22, 2024 Category: Neurology Authors: Shaohua You Yishuang Wu Yongxin Guo Meng Wu Mingzi Ran Fuyang Cao Xinyu Hao Lujia Yang Hong Zhang Weidong Mi Li Tong Source Type: research
Sevoflurane exerts antidepressant-like effects via the BDNF-TrkB pathway
In conclusion, this study provides evidence supporting the notion that sevoflurane exerts its antidepressant-like effect via the BDNF-TrkB signaling pathway.PMID:38387696 | DOI:10.1016/j.bbr.2024.114918 (Source: Brain Research)
Source: Brain Research - February 22, 2024 Category: Neurology Authors: Shaohua You Yishuang Wu Yongxin Guo Meng Wu Mingzi Ran Fuyang Cao Xinyu Hao Lujia Yang Hong Zhang Weidong Mi Li Tong Source Type: research
Sevoflurane exerts antidepressant-like effects via the BDNF-TrkB pathway
In conclusion, this study provides evidence supporting the notion that sevoflurane exerts its antidepressant-like effect via the BDNF-TrkB signaling pathway.PMID:38387696 | DOI:10.1016/j.bbr.2024.114918 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - February 22, 2024 Category: Neurology Authors: Shaohua You Yishuang Wu Yongxin Guo Meng Wu Mingzi Ran Fuyang Cao Xinyu Hao Lujia Yang Hong Zhang Weidong Mi Li Tong Source Type: research
Sevoflurane exerts antidepressant-like effects via the BDNF-TrkB pathway
In conclusion, this study provides evidence supporting the notion that sevoflurane exerts its antidepressant-like effect via the BDNF-TrkB signaling pathway.PMID:38387696 | DOI:10.1016/j.bbr.2024.114918 (Source: Brain Research)
Source: Brain Research - February 22, 2024 Category: Neurology Authors: Shaohua You Yishuang Wu Yongxin Guo Meng Wu Mingzi Ran Fuyang Cao Xinyu Hao Lujia Yang Hong Zhang Weidong Mi Li Tong Source Type: research
Effect of Propofol Infusion on Need for Rescue Antiemetics in Postanesthesia Care Unit After Volatile Anesthesia: A Retrospective Cohort Study
CONCLUSIONS: The addition of propofol infusions to volatile-based anesthesia is associated with a dose-dependent reduction in the need for rescue antiemetics in the PACU regardless of the number of prophylactic antiemetics, duration of procedure, and type of volatile agent used, without affecting PACU recovery time.PMID:38381704 | DOI:10.1213/ANE.0000000000006906 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 21, 2024 Category: Anesthesiology Authors: Juraj Sprung Atousa Deljou Darrell R Schroeder David O Warner Toby N Weingarten Source Type: research
Immunotherapeutic Properties of Dexmedetomidine on Pain Management and Cardiovascular Function in Videolaparoscopic Cholecystectomies: A Randomized, Two-Arm, Double-Blinded, Placebo-Controlled Trial
CONCLUSIONS: Dexmedetomidine provided anti-inflammatory activity, sympatholytic effect and analgesia with cardiovascular safety. It reinforces the therapeutic nature of highly selective α2-adrenergic agonists when combined within anesthetic interventions.PMID:38383315 | DOI:10.1177/15533506241234591 (Source: Surgical Innovation)
Source: Surgical Innovation - February 21, 2024 Category: Surgery Authors: Gustavo Nascimento Silva Virna Guedes Brand ão Marcelo Vaz Perez Sandoval Lage Sobrinho Jo ão Gabriel de Cerqueira Campos Villardi Priscilla Mendon ça do Sacramento Luiz Claudio Pereira Ribeiro Rossano Kepler Alvim Fiorelli Source Type: research
Effect of Propofol Infusion on Need for Rescue Antiemetics in Postanesthesia Care Unit After Volatile Anesthesia: A Retrospective Cohort Study
CONCLUSIONS: The addition of propofol infusions to volatile-based anesthesia is associated with a dose-dependent reduction in the need for rescue antiemetics in the PACU regardless of the number of prophylactic antiemetics, duration of procedure, and type of volatile agent used, without affecting PACU recovery time.PMID:38381704 | DOI:10.1213/ANE.0000000000006906 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 21, 2024 Category: Anesthesiology Authors: Juraj Sprung Atousa Deljou Darrell R Schroeder David O Warner Toby N Weingarten Source Type: research
