Inappropriate antibiotic prescribing and its determinants among outpatient children in 3 low- and middle-income countries: A multicentric community-based cohort study
by Antoine Ardillon, Lison Rambli ère, Elsa Kermorvant-Duchemin, Touch Sok, Andrianirina Zafitsara Zo, Jean-Baptiste Diouf, Pring Long, Siyin Lach, Fatoumata Diene Sarr, Laurence Borand, Felix Cheysson, Jean-Marc Collard, Perlinot Herindrainy, Agathe de Lauzanne, Muriel Vray, Elisabeth Delarocque-Astagneau, Didier Guillemot, Bich-T ram Huynh, On behalf of the BIRDY study group
BackgroundAntibiotic resistance is a global public health issue, particularly in low- and middle-income countries (LMICs), where antibiotics required to treat resistant infections are not affordable. LMICs also bear a disproportionately high burden ...
Source: PLoS Medicine - June 6, 2023 Category: Internal Medicine Authors: Antoine Ardillon Source Type: research
Metabolic Profile of Individuals with and without Type 2 Diabetes from Sub-Saharan Africa
In conclusion, the T2D group exhibited modifications in metabolites previously shown to be associated with T2D risk in populations from other areas of the world. Future studies should seek to test whether these metabolites could be used as predictors for T2D-related complications in people from sub-Saharan Africa.PMID:37264938 | DOI:10.1021/acs.jproteome.3c00070 (Source: Cell Research)
Source: Cell Research - June 2, 2023 Category: Cytology Authors: Sarah C Skinner Travis Nemkov Mor Diaw Ma ïmouna Ndour Mbaye Demba Diedhiou Djiby Sow Fatou Gueye Philom ène Lopez Philippe Connes Angelo D'Alessandro Source Type: research
Viruses, Vol. 15, Pages 1261: Novel Amplicon-Based Sequencing Approach to West Nile Virus
This study was carried out on different strains from lineage 1 and 2 from Senegal and Italy. The presented protocol/approach showed good coverage using samples derived from several vertebrate hosts and may be valuable for West Nile genomic surveillance. (Source: Viruses)
Source: Viruses - May 27, 2023 Category: Virology Authors: Moussa Mo ïse Diagne Marie Henriette Dior Ndione Giulia Mencattelli Amadou Diallo El hadji Ndiaye Marco Di Domenico Diawo Diallo Mouhamed Kane Valentina Curini Ndeye Marieme Top Maurilia Marcacci Ma ïmouna Mbanne Massimo Ancora Barbara Secondini Valeria Tags: Article Source Type: research
Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017
Malaria control is highly dependent on the effectiveness of artemisinin-based combination therapy (ACT), the current frontline malaria curative treatment. Unfortunately, the emergence and spread of parasites r... (Source: Malaria Journal)
Source: Malaria Journal - May 26, 2023 Category: Infectious Diseases Authors: Mamadou Samb Yade, Baba Di èye, Romain Coppée, Aminata Mbaye, Mamadou Alpha Diallo, Khadim Diongue, Justine Bailly, Atikatou Mama, Awa Fall, Alphonse Birane Thiaw, Ibrahima Mbaye Ndiaye, Tolla Ndiaye, Amy Gaye, Abdoulaye Tine, Younouss Diédhiou, Amadou Tags: Research Source Type: research
Hardening determinants among adult daily smokers in nine African countries: Data from the Global Adult Tobacco Survey
Prev Med Rep. 2023 May 5;34:102226. doi: 10.1016/j.pmedr.2023.102226. eCollection 2023 Aug.ABSTRACTLittle has been reported about hardening nor softening indicators in Africa where smoking prevalence is low. We aimed to examine the determinants of hardening in nine African countries. We conducted two separate analyses using data from the most recent Global Adult Tobacco Survey in Botswana, Cameroon, Egypt, Ethiopia, Kenya, Nigeria, Senegal, Tanzania, and Uganda (total sample of 72,813 respondents): 1) multilevel logistic regression analysis to assess individual and country-level factors associated with hardcore, high depen...
Source: Cancer Control - May 25, 2023 Category: Cancer & Oncology Authors: Chandrashekhar T Sreeramareddy Esteve Fernandez Ariadna Feliu Source Type: research
Viruses, Vol. 15, Pages 1233: Genomic Epidemiology of SARS-CoV-2 in Urban Settings in Senegal
p
Pierre-Edouard Fournier
We used whole genome sequencing to identify and analyze mutations in SARS-CoV-2 in urban settings during the deadliest wave of the COVID-19 epidemic—from March to April 2021—in Senegal. Nasopharyngeal samples testing positive for SARS-CoV-2 were sequenced on the Illumina NovaSeq 6000 sequencing system using the COVIDSeq protocol. A total of 291 genotypable consensus genome sequences were obtained. Phylogenetic analyses grouped the genomes into 16 distinct PANGOLIN lineages. The major lineage was B.1.1.420, despite circulation of the Alpha variant of concern (VOC)....
Source: Viruses - May 24, 2023 Category: Virology Authors: Anna Julienne Selb é Ndiaye Mamadou Beye Gora Lo Idir Kacel Aissatou Sow Nafissatou Leye Abdou Padane Aminata Mboup Halimatou Diop-Ndiaye Cheikh Sokhna Coumba Tour é Kane Philippe Colson Florence Fenollar Souleymane Mboup Pierre-Edouard Fournier Tags: Article Source Type: research
Sensitivity and specificity of human point-of-care circulating cathodic antigen (POC-CCA) test in African livestock for rapid diagnosis of schistosomiasis: A Bayesian latent class analysis
by Beatriz Calvo-Urbano, Elsa L éger, Isobel Gabain, Claudia J. De Dood, Nicolas D. Diouf, Anna Borlase, James W. Rudge, Paul L. A. M. Corstjens, Mariama Sène, Govert J. Van Dam, Martin Walker, Joanne P. Webster
Schistosomiasis is a major neglected tropical disease (NTD) affecting both humans and animals. The morbidity and mortality inflicted upon livestock in the Afrotropical region has been largely overlooked, in part due to a lack of validated sensitive and specific tests, which do not require specialist training or equipment to deliver and interpret. As stressed within the recent WHO NTD 2021 –2030 Roadmap and Rev...
Source: PLoS Neglected Tropical Diseases - May 22, 2023 Category: Tropical Medicine Authors: Beatriz Calvo-Urbano Source Type: research
Genes, Vol. 14, Pages 1107: Molecular Survey of Rodent-Borne Infectious Agents in the Ferlo Region, Senegal
This study highlights the diversity of infectious agents circulating in rodent populations and the importance of describing potential new species and evaluating their pathogenicity and zoonotic potential. (Source: Genes)
Source: Genes - May 18, 2023 Category: Genetics & Stem Cells Authors: Mangombi-Pambou Granjon Flirden Kane Niang Davoust Fenollar Mediannikov Tags: Article Source Type: research
Percutaneous coronary intervention in the management of acute coronary syndromes in Senegal : Challenges and results
CONCLUSION: Treatment of ACS by PCI is a reality in Senegal with a considerable success rate. However, intervention delays remain one of the major challenges of this management.PMID:37182378 | DOI:10.1016/j.ancard.2023.101603 (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - May 14, 2023 Category: Cardiology Authors: Serigne Cheikh Tidiane Ndao Mame Madjiguene Ka Waly Niang Mboup Rabab Yassine Abdoulaye Diallo Khadidiatou Dia Mouhamed Ch érif Mboup Source Type: research
A 24-Year-Old Woman With Cough, Arthralgia, and Skin Ulcerations
Chest. 2023 May;163(5):e223-e229. doi: 10.1016/j.chest.2022.12.038.ABSTRACTA 24-year-old Senegalese woman without remarkable history except anemia and iron deficiency related to excessive menstrual bleeding and sickle cell trait was admitted to our internal medicine department with 4-month fever, weight loss (-13 kg), dyspnea for limited efforts, intermittent productive cough, and bilateral metacarpophalangeal (MCP) and interphalangeal arthralgia. She was born and lived in France. She traveled previously to Senegal in 2015. She had no history of tobacco, alcohol, or drug use nor proximity with animals. She was taking no me...
Source: Chest - May 10, 2023 Category: Respiratory Medicine Authors: Thibault Leveque Anastasia Pavlidi Thomas Lacoste-Palasset Aur élie Cazes Jonathan Messika Philippe Montravers Brice Lortat-Jacob Yves-Herv é Castier Vincent Bunel Rapha ël Borie Damien S ène Yves Allenbach Bruno M égarbane Clo é Comarmond Source Type: research
A 24-Year-Old Woman With Cough, Arthralgia, and Skin Ulcerations
Chest. 2023 May;163(5):e223-e229. doi: 10.1016/j.chest.2022.12.038.ABSTRACTA 24-year-old Senegalese woman without remarkable history except anemia and iron deficiency related to excessive menstrual bleeding and sickle cell trait was admitted to our internal medicine department with 4-month fever, weight loss (-13 kg), dyspnea for limited efforts, intermittent productive cough, and bilateral metacarpophalangeal (MCP) and interphalangeal arthralgia. She was born and lived in France. She traveled previously to Senegal in 2015. She had no history of tobacco, alcohol, or drug use nor proximity with animals. She was taking no me...
Source: Chest - May 10, 2023 Category: Respiratory Medicine Authors: Thibault Leveque Anastasia Pavlidi Thomas Lacoste-Palasset Aur élie Cazes Jonathan Messika Philippe Montravers Brice Lortat-Jacob Yves-Herv é Castier Vincent Bunel Rapha ël Borie Damien S ène Yves Allenbach Bruno M égarbane Clo é Comarmond Source Type: research
Evaluation of knowledge of priapism in sickle cell patients in Senegal
ConclusionPriapism is a common complication of sickle cell disease in Senegalese adults which is not well known by sickle cell patients. The health authorities must undertake efforts to raise awareness of priapism as a complication amongst sickle cell patients. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - May 10, 2023 Category: Urology & Nephrology Source Type: research
Identification of < i > Bulinus forskalii < /i > as a potential intermediate host of < i > Schistosoma h æmatobium < /i > in Senegal
by Papa Mouhamadou Gaye, Souleymane Doucour é, Doudou Sow, Cheikh Sokhna, Stéphane Ranque
Understanding the transmission ofSchistosoma h æmatobium in the Senegal River Delta requires knowledge of the snails serving as intermediate hosts. Accurate identification of both the snails and the infectingSchistosoma species is therefore essential. Cercarial emission tests and multi-locus (COX1 and ITS) genetic analysis were performed onBulinus forskalii snails to confirm their susceptibility toS.h æmatobium infection. A total of 55Bulinus forskalii, adequately identified by MALDI-TOF mass spectrometry, were assessed. Cercaria...
Source: PLoS Neglected Tropical Diseases - May 9, 2023 Category: Tropical Medicine Authors: Papa Mouhamadou Gaye Source Type: research
COVID-19 surveillance in Democratic Republic of Congo, Nigeria, Senegal and Uganda: strengths, weaknesses and key Lessons
As part of efforts to rapidly identify and care for individuals with COVID-19, trace and quarantine contacts, and monitor disease trends over time, most African countries implemented interventions to strengthe... (Source: BMC Public Health)
Source: BMC Public Health - May 8, 2023 Category: Consumer Health News Authors: Olufunmilayo Ibitola Fawole, Segun Bello, Ayo Stephen Adebowale, Eniola Adetola Bamgboye, Mobolaji Modinat Salawu, Rotimi Felix Afolabi, Magbagbeola David Dairo, Alice Namale, Suzanne Kiwanuka, Fred Monje, Noel Namuhani, Steven Kabwama, Susan Kizito, Rawl Tags: Research Source Type: research
Hepatitis B prevention and treatment needs in women in Senegal (ANRS 12356 AmBASS survey)
Although mother-to-child transmission (MTCT) of hepatitis B virus (HBV) is prevalent in West Africa, epidemiological data on HBV infection in women remain scarce. We studied i) hepatitis B surface antigen (HBs... (Source: BMC Public Health)
Source: BMC Public Health - May 5, 2023 Category: Consumer Health News Authors: Tchadine Djaogol, Lauren P érières, Fabienne Marcellin, Assane Diouf, Maria Patrizia Carrieri, Aldiouma Diallo and Sylvie Boyer Tags: Research Source Type: research
